ATE87925T1 - Erythromycin-a-derivate und verfahren zu ihrer herstellung. - Google Patents

Erythromycin-a-derivate und verfahren zu ihrer herstellung.

Info

Publication number
ATE87925T1
ATE87925T1 AT87311097T AT87311097T ATE87925T1 AT E87925 T1 ATE87925 T1 AT E87925T1 AT 87311097 T AT87311097 T AT 87311097T AT 87311097 T AT87311097 T AT 87311097T AT E87925 T1 ATE87925 T1 AT E87925T1
Authority
AT
Austria
Prior art keywords
group
lower alkyl
erythromycin
together form
formula
Prior art date
Application number
AT87311097T
Other languages
English (en)
Inventor
Shigeo Morimoto
Tohru Matsunaga
Takashi Adachi
Masato Kashimura
Toshifumi Asaka
Kaoru Sota
Yoshiaki Watanabe
Kazuto Sekiuchi
Original Assignee
Taisho Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Taisho Pharmaceutical Co Ltd filed Critical Taisho Pharmaceutical Co Ltd
Application granted granted Critical
Publication of ATE87925T1 publication Critical patent/ATE87925T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT87311097T 1986-12-17 1987-12-16 Erythromycin-a-derivate und verfahren zu ihrer herstellung. ATE87925T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP30065386 1986-12-17
EP87311097A EP0272110B1 (de) 1986-12-17 1987-12-16 Erythromycin-A-Derivate und Verfahren zu ihrer Herstellung

Publications (1)

Publication Number Publication Date
ATE87925T1 true ATE87925T1 (de) 1993-04-15

Family

ID=17887449

Family Applications (1)

Application Number Title Priority Date Filing Date
AT87311097T ATE87925T1 (de) 1986-12-17 1987-12-16 Erythromycin-a-derivate und verfahren zu ihrer herstellung.

Country Status (5)

Country Link
US (1) US4990602A (de)
EP (1) EP0272110B1 (de)
KR (1) KR960000434B1 (de)
AT (1) ATE87925T1 (de)
DE (1) DE3785315T2 (de)

Families Citing this family (104)

* Cited by examiner, † Cited by third party
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CN101875678B (zh) 2009-04-30 2012-06-27 浙江华义医药有限公司 一种制备克拉霉素的方法
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CN102250173B (zh) * 2010-05-18 2015-07-08 上海医药工业研究院 一种6-o-甲基红霉素a衍生物和克拉霉素的制备方法
CN102250180B (zh) * 2010-05-18 2015-07-22 上海医药工业研究院 2’,4”-o-二(三甲基硅基)-红霉素a衍生物和克拉霉素制备方法
WO2011146829A1 (en) * 2010-05-20 2011-11-24 Cempra Pharmaceuticals, Inc. Processes for preparing macrolides and ketolides and intermediates therefor
JP6042334B2 (ja) 2010-09-10 2016-12-14 センプラ ファーマシューティカルズ，インコーポレイテッド 疾患治療のための水素結合形成フルオロケトライド
CN104470527B (zh) 2012-03-27 2019-05-28 森普拉制药公司 用于施用大环内酯抗生素的肠胃外制剂
CN103880901A (zh) * 2012-12-23 2014-06-25 菏泽市方明制药有限公司 一种克拉霉素中间甲化物的制备方法
RU2015138796A (ru) 2013-03-14 2017-04-19 Семпра Фармасьютикалс, Инк. Способы и составы для лечения респираторных заболеваний
WO2014145210A1 (en) 2013-03-15 2014-09-18 Cempra Pharmaceuticals, Inc. Convergent processes for preparing macrolide antibacterial agents
CN105418709A (zh) * 2015-12-18 2016-03-23 山东理工职业学院 一种制备克拉霉素杂质的方法
CN106749462A (zh) * 2016-11-11 2017-05-31 杭州新桂实业有限公司 一种高效绿色克拉霉素中间体合成工艺
CN115286654B (zh) * 2022-07-07 2023-07-18 浙江国邦药业有限公司 一种克拉霉素中间体的合成方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
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JPS60214796A (ja) * 1984-04-06 1985-10-28 Taisho Pharmaceut Co Ltd ６−０−メチルエリスロマイシン類の製法
PT82162B (en) * 1985-03-12 1987-08-06 Beecham Group Plc Chemical compounds
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Also Published As

Publication number Publication date
DE3785315T2 (de) 1993-07-22
US4990602A (en) 1991-02-05
KR880007524A (ko) 1988-08-27
KR960000434B1 (ko) 1996-01-06
EP0272110B1 (de) 1993-04-07
EP0272110A2 (de) 1988-06-22
EP0272110A3 (en) 1989-10-25
DE3785315D1 (de) 1993-05-13

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EELA Cancelled due to lapse of time