ATE88894T1 - Methode zur behandlung von kachexie und bestimmte dafuer anzuwendende verbindungen. - Google Patents

Methode zur behandlung von kachexie und bestimmte dafuer anzuwendende verbindungen.

Info

Publication number
ATE88894T1
ATE88894T1 AT89306147T AT89306147T ATE88894T1 AT E88894 T1 ATE88894 T1 AT E88894T1 AT 89306147 T AT89306147 T AT 89306147T AT 89306147 T AT89306147 T AT 89306147T AT E88894 T1 ATE88894 T1 AT E88894T1
Authority
AT
Austria
Prior art keywords
hydrogen
alkyl
cachexia
treatment
halogen
Prior art date
Application number
AT89306147T
Other languages
English (en)
Inventor
Yo Takiguchi
Jun Ohsumi
Yasuo Shimoji
Kazuhiko Sasagawa
Original Assignee
Sankyo Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co filed Critical Sankyo Co
Application granted granted Critical
Publication of ATE88894T1 publication Critical patent/ATE88894T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Storage Of Fruits Or Vegetables (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT89306147T 1988-06-16 1989-06-16 Methode zur behandlung von kachexie und bestimmte dafuer anzuwendende verbindungen. ATE88894T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP14913788 1988-06-16
EP89306147A EP0347252B1 (de) 1988-06-16 1989-06-16 Methode zur Behandlung von Kachexie und bestimmte dafür anzuwendende Verbindungen

Publications (1)

Publication Number Publication Date
ATE88894T1 true ATE88894T1 (de) 1993-05-15

Family

ID=15468558

Family Applications (2)

Application Number Title Priority Date Filing Date
AT92201695T ATE121744T1 (de) 1988-06-16 1989-06-16 Neue triazolopyrimidin- und pyrazolopyrimidinderivate zur behandlung von kachexie.
AT89306147T ATE88894T1 (de) 1988-06-16 1989-06-16 Methode zur behandlung von kachexie und bestimmte dafuer anzuwendende verbindungen.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT92201695T ATE121744T1 (de) 1988-06-16 1989-06-16 Neue triazolopyrimidin- und pyrazolopyrimidinderivate zur behandlung von kachexie.

Country Status (9)

Country Link
US (2) US5055479A (de)
EP (2) EP0508549B1 (de)
JP (1) JPH0276880A (de)
KR (1) KR910000737A (de)
AT (2) ATE121744T1 (de)
CA (1) CA1329199C (de)
DE (2) DE68906309T2 (de)
ES (1) ES2057126T3 (de)
IE (2) IE930392L (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1330079C (en) * 1988-10-13 1994-06-07 Michihiko Tsujitani Pyrrolo (3,2-e)pyrazolo(1,5-a)pyrimidine derivative and medicine comprising the same
US5264220A (en) * 1991-11-12 1993-11-23 Long David M Jr Method of extending the vascular dwell-time of particulate therapeutic and particulate diagnostic agents
JPH10218881A (ja) * 1997-02-03 1998-08-18 Pola Chem Ind Inc 新規なピロロピラゾロピリミジン誘導体
TWI271406B (en) 1999-12-13 2007-01-21 Eisai Co Ltd Tricyclic condensed heterocyclic compounds, preparation method of the same and pharmaceuticals comprising the same
US20020061897A1 (en) 2000-03-30 2002-05-23 Elliott Richard L. Neuropeptide Y antagonists
JP2002043785A (ja) 2000-07-28 2002-02-08 Murata Mfg Co Ltd シールドケース及びそれを用いた電子機器及びそれを用いた電子装置及びシールドケースの製造方法
DZ3415A1 (fr) 2000-08-31 2002-03-07 Chiron Corp Guanidinobenzamides comme mc4-r agonistes.
PT1385823E (pt) 2001-04-09 2007-01-31 Novartis Vaccines & Diagnostic Compostos de guanidino como agonistas do receptor de melanocortina-4 (r-mc4)
DK1433480T3 (da) * 2001-07-13 2011-04-11 Btg Internat Ltd Company Lægemiddel indeholdende pyrimidin-derivat
US20030195187A1 (en) * 2002-02-04 2003-10-16 Chiron Corporation Guanidino compounds
US20050124652A1 (en) * 2002-02-04 2005-06-09 Rustum Boyce Guanidino compounds
US20030207814A1 (en) * 2002-02-04 2003-11-06 Chiron Corporation Novel guanidinyl derivatives
US20070004743A1 (en) * 2002-02-25 2007-01-04 Xiao Linda L Intranasal administration of mc4-r agonists
DE60333937D1 (de) * 2002-05-23 2010-10-07 Novartis Vaccines & Diagnostic Substituierte quinazolinone verbindungen
US7051505B2 (en) * 2002-08-21 2006-05-30 Greg Brannstrom Tomato harvester
US7329658B2 (en) * 2003-02-06 2008-02-12 Pfizer Inc Cannabinoid receptor ligands and uses thereof
US7176210B2 (en) * 2003-02-10 2007-02-13 Pfizer Inc. Cannabinoid receptor ligands and uses thereof
KR20060018217A (ko) * 2003-05-23 2006-02-28 카이론 코포레이션 Mc4-r 작용제로서 구아니디노-치환된 퀴나졸리논 화합물
US20050009919A1 (en) * 2003-07-07 2005-01-13 Clouatre Dallas L. Treating cachexia and excessive catabolism with (-)-hydroxycitric acid
WO2005051391A1 (en) * 2003-11-19 2005-06-09 Chiron Corporation Quinazolinone compounds with reduced bioaccumulation
US8257684B2 (en) * 2008-03-26 2012-09-04 Neurosigma, Inc. Methods for identifying and targeting autonomic brain regions
BRPI0911659B8 (pt) 2008-04-15 2021-05-25 Eisai R&D Man Co Ltd composto 3-fenilpirazolo[5,1-b]tiazol e composição farmacêutica compreendendo o mesmo
GB0917774D0 (en) * 2009-10-09 2009-11-25 Senexis Ltd Novel pharmaceutical compounds
GB0917775D0 (en) 2009-10-09 2009-11-25 Btg Int Ltd Novel pharmaceutical compounds
WO2012027239A1 (en) * 2010-08-23 2012-03-01 Schering Corporation NOVEL PYRAZOLO[1,5-a]PYRROLO[3,2-e]PYRIMIDINE DERIVATIVES AS mTOR INHIBITORS
KR20160101398A (ko) 2015-02-17 2016-08-25 순천대학교 산학협력단 바륨타이타네이트층을 포함하는 복합 세라믹 전극의 제조방법

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS51141896A (en) * 1975-05-31 1976-12-07 Sankyo Co Ltd Process for preparing fused ring triazoropyrimidine derivatives
DE2704030A1 (de) * 1976-02-12 1977-08-18 Sandoz Ag Neue organische verbindungen, ihre herstellung und verwendung
JPS5353697A (en) * 1976-10-20 1978-05-16 Sankyo Co Ltd Tricyclic triazolopyrimidine derivatives
US4619933A (en) * 1979-09-28 1986-10-28 The Upjohn Company 6-aryl pyrimidines for treating aplastic anemia
GB2138418B (en) * 1982-02-19 1985-12-04 Mochida Pharm Co Ltd Novel s-triazole(1,5-a)pyrimidine derivatives
CA1330079C (en) * 1988-10-13 1994-06-07 Michihiko Tsujitani Pyrrolo (3,2-e)pyrazolo(1,5-a)pyrimidine derivative and medicine comprising the same

Also Published As

Publication number Publication date
EP0347252A2 (de) 1989-12-20
EP0508549A2 (de) 1992-10-14
IE62915B1 (en) 1995-03-08
EP0347252A3 (de) 1991-03-27
EP0347252B1 (de) 1993-05-05
IE891963L (en) 1989-12-16
ATE121744T1 (de) 1995-05-15
JPH0276880A (ja) 1990-03-16
EP0508549B1 (de) 1995-04-26
EP0508549A3 (de) 1992-11-25
DE68906309D1 (de) 1993-06-09
DE68906309T2 (de) 1994-01-05
US5086057A (en) 1992-02-04
US5055479A (en) 1991-10-08
DE68922408D1 (de) 1995-06-01
CA1329199C (en) 1994-05-03
IE930392L (en) 1989-12-16
KR910000737A (ko) 1991-01-30
ES2057126T3 (es) 1994-10-16

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