ATE89315T1 - Faktor viii-analog, verfahren zu dessen herstellung und dieses enthaltende zusammensetzung. - Google Patents

Faktor viii-analog, verfahren zu dessen herstellung und dieses enthaltende zusammensetzung.

Info

Publication number
ATE89315T1
ATE89315T1 AT88402078T AT88402078T ATE89315T1 AT E89315 T1 ATE89315 T1 AT E89315T1 AT 88402078 T AT88402078 T AT 88402078T AT 88402078 T AT88402078 T AT 88402078T AT E89315 T1 ATE89315 T1 AT E89315T1
Authority
AT
Austria
Prior art keywords
factor viii
analogue
production
composition containing
deleted
Prior art date
Application number
AT88402078T
Other languages
English (en)
Inventor
Pierre Meulien
Andrea Pavirani
Original Assignee
Transgene Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9354094&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE89315(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Transgene Sa filed Critical Transgene Sa
Application granted granted Critical
Publication of ATE89315T1 publication Critical patent/ATE89315T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT88402078T 1987-08-11 1988-08-10 Faktor viii-analog, verfahren zu dessen herstellung und dieses enthaltende zusammensetzung. ATE89315T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8711415A FR2619314B1 (fr) 1987-08-11 1987-08-11 Analogue du facteur viii, procede de preparation et composition pharmaceutique le contenant
EP88402078A EP0303540B1 (de) 1987-08-11 1988-08-10 Faktor VIII-Analog, Verfahren zu dessen Herstellung und dieses enthaltende Zusammensetzung

Publications (1)

Publication Number Publication Date
ATE89315T1 true ATE89315T1 (de) 1993-05-15

Family

ID=9354094

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88402078T ATE89315T1 (de) 1987-08-11 1988-08-10 Faktor viii-analog, verfahren zu dessen herstellung und dieses enthaltende zusammensetzung.

Country Status (8)

Country Link
US (1) US5112950A (de)
EP (1) EP0303540B1 (de)
JP (1) JP2694280B2 (de)
AT (1) ATE89315T1 (de)
CA (1) CA1341169C (de)
DE (1) DE3880922T2 (de)
ES (1) ES2054842T3 (de)
FR (1) FR2619314B1 (de)

Families Citing this family (99)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
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US6346513B1 (en) 1987-06-12 2002-02-12 Baxter Trading Gmbh Proteins with factor VIII activity: process for their preparation using genetically-engineered cells and pharmaceutical compositions containing them
SE465222C5 (sv) * 1989-12-15 1998-02-10 Pharmacia & Upjohn Ab Ett rekombinant, humant faktor VIII-derivat och förfarande för dess framställning
DE69101634T4 (de) * 1990-01-26 1994-12-01 Immuno Ag Rekombinant hergestellte blutfaktoren, verfahren zur exprimierung besagter blutfaktoren sowie in besagtem prozess verwendeter rekombinanter vaccina-virus.
FR2657884B1 (fr) * 1990-02-05 1994-09-02 Tm Innovation Procede pour la preparation du facteur viii humain et d'analogues du facteur viii.
US5997864A (en) 1995-06-07 1999-12-07 Novo Nordisk A/S Modified factor VII
US5833982A (en) * 1991-02-28 1998-11-10 Zymogenetics, Inc. Modified factor VII
US5661008A (en) * 1991-03-15 1997-08-26 Kabi Pharmacia Ab Recombinant human factor VIII derivatives
DE69229390T2 (de) * 1991-08-26 1999-11-11 Immuno Ag, Wien Direkt molekuläre Klonierung eines modifizierten Genoms eines Chordopocken-Virus
DK53792D0 (da) * 1992-04-24 1992-04-24 Novo Nordisk As Fremgangsmaade til fremstilling af proteiner
WO1994011525A1 (en) * 1992-11-17 1994-05-26 Novo Nordisk A/S Improved recombinant production of proteins having factor viii:c activity
SE504074C2 (sv) * 1993-07-05 1996-11-04 Pharmacia Ab Proteinberedning för subkutan, intramuskulär eller intradermal administrering
DE4437544A1 (de) * 1994-10-20 1996-04-25 Behringwerke Ag Einsatz von vWF-enthaltenden Konzentraten als Kombinationstherapie bei Therapie mit Antithrombotika und Fibrinolytika
US6221349B1 (en) 1998-10-20 2001-04-24 Avigen, Inc. Adeno-associated vectors for expression of factor VIII by target cells
US6200560B1 (en) * 1998-10-20 2001-03-13 Avigen, Inc. Adeno-associated virus vectors for expression of factor VIII by target cells
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EP1233064A1 (de) 2001-02-09 2002-08-21 Aventis Behring Gesellschaft mit beschränkter Haftung Modifizierte Faktor VIII cDNA und deren Verwendung bei der Produktion von Faktor VIII
EP1284290A1 (de) * 2001-08-08 2003-02-19 Aventis Behring GmbH Erhöhung der Expression von Faktor VIII durch Insertion von spleissbaren Nukleotidsequenzen in Faktor VIII cDNA
WO2003057709A2 (en) * 2001-10-19 2003-07-17 Sirna Therapeutics, Inc Method and reagent for the detection of proteins and peptides
EP1424344A1 (de) * 2002-11-29 2004-06-02 Aventis Behring Gesellschaft mit beschränkter Haftung Modifizierte cDNA des Factors VIII und Derivate davon
US7041635B2 (en) 2003-01-28 2006-05-09 In2Gen Co., Ltd. Factor VIII polypeptide
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EP2345731B1 (de) 2003-09-30 2015-10-21 The Trustees of the University of Pennsylvania Adenoassoziierte Virus-Claden, Sequenzen, diese enthaltende Vektoren und ihre Verwendungen
EP1789096A4 (de) * 2004-09-07 2009-07-08 Archemix Corp Aptamere für den von-willebrand-faktor und ihre verwendung als therapeutika für thrombotische erkrankungen
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TW202003554A (zh) 2013-08-14 2020-01-16 美商百歐維拉提夫治療公司 因子ｖｉｉｉ－ｘｔｅｎ融合物及其用途
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Family Cites Families (5)

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ES8801674A1 (es) * 1985-04-12 1988-02-16 Genetics Inst Un procedimiento para la preparacion de una proteina que presenta actividad procoagulante.
KR910006424B1 (ko) * 1985-08-21 1991-08-24 인코텍스 비.브이 편성브리프(brief) 제조방법
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IL84168A0 (en) * 1986-10-15 1988-03-31 Rorer Int Overseas Human factor viii-c analogs,process for the preparation thereof and pharmaceutical compositions containing the same

Also Published As

Publication number Publication date
EP0303540B1 (de) 1993-05-12
FR2619314A1 (fr) 1989-02-17
DE3880922D1 (de) 1993-06-17
US5112950A (en) 1992-05-12
JP2694280B2 (ja) 1997-12-24
ES2054842T3 (es) 1994-08-16
DE3880922T2 (de) 1993-08-26
EP0303540A1 (de) 1989-02-15
CA1341169C (fr) 2001-01-16
JPS6479124A (en) 1989-03-24
FR2619314B1 (fr) 1990-06-15

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