ATE91629T1 - Adhesin-antigene, antikoerper und dns-fragmente die das antigen kodieren, verfahren und mittel zur diagnose und immunisierung, usw. - Google Patents

Adhesin-antigene, antikoerper und dns-fragmente die das antigen kodieren, verfahren und mittel zur diagnose und immunisierung, usw.

Info

Publication number
ATE91629T1
ATE91629T1 AT85902487T AT85902487T ATE91629T1 AT E91629 T1 ATE91629 T1 AT E91629T1 AT 85902487 T AT85902487 T AT 85902487T AT 85902487 T AT85902487 T AT 85902487T AT E91629 T1 ATE91629 T1 AT E91629T1
Authority
AT
Austria
Prior art keywords
antigen
adhesin
antibodies
immunization
diagnosis
Prior art date
Application number
AT85902487T
Other languages
English (en)
Inventor
Frederik Carl Peter Lindberg
Bjoern Olof Lund
Britt Monika Baaga
Mari Elisabet Norgren
Mikael Goeransson
Bernt Eric Anund Uhlin
Jan Staffan Normark
David Lee Lark
Original Assignee
Symbicom Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Symbicom Ab filed Critical Symbicom Ab
Application granted granted Critical
Publication of ATE91629T1 publication Critical patent/ATE91629T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/025—Enterobacteriales, e.g. Enterobacter
    • A61K39/0258—Escherichia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/21—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pseudomonadaceae (F)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/22—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/235—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bordetella (G)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/245—Escherichia (G)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
    • C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/33—Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/82—Subcellular parts of microorganisms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/806—Antigenic peptides or proteins
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/82—Proteins from microorganisms
    • Y10S530/825—Bacteria

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Mycology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
AT85902487T 1984-05-02 1985-05-02 Adhesin-antigene, antikoerper und dns-fragmente die das antigen kodieren, verfahren und mittel zur diagnose und immunisierung, usw. ATE91629T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DK2190/84A DK219084D0 (da) 1984-05-02 1984-05-02 Antigen
PCT/DK1985/000045 WO1985005037A1 (en) 1984-05-02 1985-05-02 Adhesin antigens, antibodies and dna fragment encoding the antigen, methods and means for diagnosis and immunization etc.
EP85902487A EP0179887B1 (de) 1984-05-02 1985-05-02 Adhesin-antigene, antikörper und dns-fragmente die das antigen kodieren, verfahren und mittel zur diagnose und immunisierung, usw.

Publications (1)

Publication Number Publication Date
ATE91629T1 true ATE91629T1 (de) 1993-08-15

Family

ID=8110676

Family Applications (1)

Application Number Title Priority Date Filing Date
AT85902487T ATE91629T1 (de) 1984-05-02 1985-05-02 Adhesin-antigene, antikoerper und dns-fragmente die das antigen kodieren, verfahren und mittel zur diagnose und immunisierung, usw.

Country Status (13)

Country Link
US (3) US4795803A (de)
EP (1) EP0179887B1 (de)
JP (2) JP2974028B2 (de)
KR (1) KR950000688B1 (de)
AT (1) ATE91629T1 (de)
AU (1) AU593770B2 (de)
CA (1) CA1340847C (de)
DE (1) DE3587468T2 (de)
DK (2) DK219084D0 (de)
FI (1) FI93310C (de)
IE (1) IE59826B1 (de)
RU (1) RU1787165C (de)
WO (1) WO1985005037A1 (de)

Families Citing this family (58)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4736017A (en) * 1984-04-30 1988-04-05 The Board Of Trustees Of The Leland Stanford Junior University Chemically defined vaccine against urinary infections
US4584195A (en) * 1984-06-21 1986-04-22 The Board Of Trustees Of The Leland Stanford Junior University Broad spectrum vaccine against gonorrhea
US4740585A (en) * 1984-07-30 1988-04-26 The Board Of Trustees Of The Leland Stanford Junior University Synthetic vaccine against urinary infections
US5288617A (en) * 1984-10-31 1994-02-22 Commonwealth Scientific And Industrial Research Organization Method of producing an antigenic preparation
WO1986002557A1 (en) * 1984-10-31 1986-05-09 Commonwealth Scientific And Industrial Research Or Improved antigenic preparation
IL78775A (en) * 1985-05-15 1992-06-21 Biotech Australia Pty Ltd Oral vaccines
EP0211352B1 (de) * 1985-08-01 1994-03-16 Miles Inc. Schützende Antikörper gegen serotypische Determinanten von flagellären Antigenen
US4900659A (en) * 1986-01-30 1990-02-13 Enzo Biochem, Inc. Nucleotide sequence composition and method for detection of Neisseria gonorrhoeae and method for screening for a nucleotide sequence that is specific for a genetically distinct group
US4801690A (en) * 1986-03-24 1989-01-31 Bactex, Inc. Novel lectins derived from bacterial pili
SE8601940D0 (sv) * 1986-04-25 1986-04-25 Kabigen Ab Preparation of fused proteins, antibodies and processes therefor
US4786592A (en) * 1986-06-18 1988-11-22 Scripps Clinic And Research Foundation Neisseria gonorrhoeae lectin useful as a vaccine and diagnostic marker and means for producing this lectin
US7087742B1 (en) 1986-11-24 2006-08-08 Gen-Probe Incorporated Oligonucleotide probes for the detection and/or quantitation of non-viral organisms
US7090972B1 (en) 1986-11-24 2006-08-15 Gen-Probe Incorporated Methods for determining the presence of non-viral organisms in a sample
US5036003A (en) * 1987-08-21 1991-07-30 Monsanto Company Antibodies to VPF
AU601510B2 (en) * 1987-11-06 1990-09-13 Immunomed Corporation Preparation of bacterium pili subunits and vaccines containing pili subunits
SE8801894D0 (sv) * 1988-05-20 1988-05-20 Alfa Laval Agri Int Fibronektinbindande protein
US5055455A (en) 1988-09-28 1991-10-08 Brigham And Women's Hospital Capsular polysaccharide adhesin antigen, preparation, purification and use
US7172863B1 (en) 1988-12-09 2007-02-06 Gen-Probe Incorporated Nucleic acid probes and methods for detecting Neisseria gonorrhoeae
CA1340530C (en) * 1989-04-28 1999-05-04 Kok Kheong Lee Synthetic pseudomonas aeruginosa pilin peptide and related vaccines and diagnostics
SE8901687D0 (sv) * 1989-05-11 1989-05-11 Alfa Laval Agri Int Fibronectin binding protein as well as its preparation
US5202113A (en) * 1990-04-30 1993-04-13 The United States Of America As Represented By The Department Of Health And Human Services Plaque-inhibiting protein from bacteroides loeschei and methods for using the same
ES2127198T3 (es) * 1990-08-02 1999-04-16 Antex Biolog Inc Receptores de adhesion para microorganismos patogenos u oportunistas.
US5440014A (en) * 1990-08-10 1995-08-08 H+E,Uml/Oo/ K; Magnus Fibronectin binding peptide
EP0563240A1 (de) * 1990-12-21 1993-10-06 MicroCarb Inc. Lipid-rezeptoren für mikroorganismen und korrespondierende adhesine, dna-sequenzen kodierend für adhesine, und ihre anwendung
US5843463A (en) * 1990-12-21 1998-12-01 Antexbiologics, Inc. Adhesin-oligosaccharide conjugate vaccine for Haemophilus influenzae
US5834591A (en) * 1991-01-31 1998-11-10 Washington University Polypeptides and antibodies useful for the diagnosis and treatment of pathogenic neisseria and other microorganisms having type 4 pilin
US5980908A (en) * 1991-12-05 1999-11-09 Alfa Laval Ab Bacterial cell surface protein with fibronectin, fibrinogen, collagen and laminin binding ability, process for the manufacture of the protein and prophylactic treatment
AU662783B2 (en) * 1992-01-08 1995-09-14 De Staat Der Nederlanden Vertegenwoordigd Door De Minister Van Welzijn, Volksgezonheid En Cultuur Whooping cough vaccine
JP3429313B2 (ja) * 1993-05-18 2003-07-22 オハイオ・ステイト・リサーチ・ファウンデーション 中耳炎ワクチン
US5648240A (en) * 1994-05-24 1997-07-15 Texas A&M University MHC II analog from Staphylococcus aureus
WO1996000233A1 (en) * 1994-06-24 1996-01-04 Children's Hospital And Medical Center Escherichia coli o157:h7 epithelial adhesin
DE19534579C2 (de) * 1995-09-18 2000-06-08 Max Planck Gesellschaft Nucleinsäure-Moleküle codierend Proteine, die die Adhäsion von Neisseria-Zellen an humane Zellen vermitteln
US6872398B2 (en) * 1995-12-22 2005-03-29 The United States Of America As Represented By The Secretary Of The Army Conjugate vaccine against gram-negative bacterial infections
NZ333250A (en) * 1996-06-10 2000-05-26 Thomas Boren Helicobacter pylori blood group antigen binding adhesion protein
EP1047784B2 (de) * 1998-01-14 2015-03-18 Novartis Vaccines and Diagnostics S.r.l. Antigene aus neisseria meningitidis
US7252828B2 (en) 1998-07-15 2007-08-07 The Brigham And Women's Hospital, Inc. Polysaccharide vaccine for staphylococcal infections
US6692739B1 (en) 1998-08-31 2004-02-17 Inhibitex, Inc. Staphylococcal immunotherapeutics via donor selection and donor stimulation
EP1121149A4 (de) * 1998-08-31 2002-03-20 Inhibitex Inc Immunotherapeutika gegen staphylokokkus mittels donor selektion und donor stimulation
US20040001863A1 (en) * 1998-12-03 2004-01-01 Shau-Chi Chi Immortal cell line derived from grouper Epinephelus coioides and its applications therein
GB9924351D0 (en) * 1999-10-14 1999-12-15 Brennan Frank Immunomodulation methods and compositions
ATE385808T1 (de) * 1999-12-21 2008-03-15 Merial Sas Mindestens ein cryptosporidium parvum-antigen und mindestens ein antigen eines anderen darmkrankheitserregers enthaltende zusammensetzungen und impfstoffe
CA2881568C (en) * 2000-10-27 2019-09-24 Novartis Vaccines And Diagnostics, Inc. Nucleic acids and proteins from streptococcus groups a & b
PT1377314E (pt) 2001-01-26 2012-01-02 Inhibitex Inc Anticorpos monoclonais para a proteína clfa e método de utilização no tratamento ou prevenção de infecções
US7396822B2 (en) 2001-05-24 2008-07-08 Vaxiion Therapeutics, Inc. Immunogenic minicells and methods of use
US20030194798A1 (en) 2001-05-24 2003-10-16 Surber Mark W. Minicell compositions and methods
US7132101B2 (en) * 2002-02-27 2006-11-07 Duquesne University Of The Holy Ghost Compositions and methods for eliciting an immune response to gram-negative bacterial infections
US20040067544A1 (en) * 2002-06-27 2004-04-08 Viola Vogel Use of adhesion molecules as bond stress-enhanced nanoscale binding switches
PL229487B1 (pl) 2002-11-12 2018-07-31 Brigham & Womens Hospital Inc Kompozycja zawierająca polimer β-1,6-glukozaminy, kompozycja zawierająca przeciwciało, kompozycja farmaceutyczna, sposób wytwarzania wyodrębnionego polisacharydu, sposób identyfikacji obecności deacetylowanej poli-N-acetyloglukozaminy (dPNAG) i/ lub poli-N-acetyloglukozaminy (PNAG), wyodrębniony polisacharyd do zastosowania w leczeniu lub profilaktyce zakażenia, wyodrębniony polisacharyd do zastosowania do wytwarzania przeciwciał, w tym przeciwciał monoklonalnych, wyodrębniony polisacharyd do zastosowania w identyfikacji przeciwciała monoklonalnego
AU2003290867A1 (en) 2002-11-12 2004-06-03 The Brigham And Women's Hospital, Inc. Methods and products for treating staphylococcal infections
WO2006055024A2 (en) * 2004-04-05 2006-05-26 Vaxiion Therapeutics, Inc. Minicells as vaccines
ES2415358T3 (es) 2004-04-21 2013-07-25 The Brigham And Women's Hospital, Inc. Péptidos de fijación a la poli-N-acetil glucosamina (PNAG/DPNAG) y procedimientos para el uso de los mismos
US7585236B2 (en) * 2006-08-02 2009-09-08 Wilson Sporting Goods Co. Game ball having optimally positioned grooves and/or ridges
US8251846B2 (en) * 2006-08-02 2012-08-28 Wilson Sporting Goods Co. Game ball having optimally positioned grooves
US7686713B2 (en) * 2007-04-11 2010-03-30 Wilson Sporting Goods Co. Racquet stringing machine
CN101784655A (zh) * 2007-04-27 2010-07-21 菲尼克斯股份有限公司 可溶性重组二十面体病毒样颗粒的改良生成和体内装配
CN102159540B (zh) 2008-07-21 2015-08-12 布赖汉姆妇女医院 与合成的β-1,6葡糖胺寡糖相关的方法和组合物
CA2827443C (en) 2011-02-15 2021-07-06 Vaxiion Therapeutics, Inc. Therapeutic compositions and methods for antibody and fc-containing targeting molecule-based targeted delivery of bioactive molecules by bacterial minicells
US12397014B2 (en) 2019-02-05 2025-08-26 The Brigham And Women's Hospital, Inc. Polysaccharide compositions for use in treating filariasis

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU853813B (en) 1913-03-31 1914-04-11 George Reid Angus Improvements in the manufacture of filter frames for beer and other liquids
GB1472624A (en) * 1974-09-02 1977-05-04 Canadian Patents Dev Enteric disease vaccine
US4461838A (en) * 1975-04-25 1984-07-24 Bactex, Inc. Gonococcal Pili processes for the preparation thereof and the use thereof for the detection of and prevention of infections caused by Neisseria gonorrhoeae
BE841068A (fr) * 1975-04-25 1976-10-25 Procede de preparation de cristaux de poils gonococciques et leurs applications a la detection et a la prevention des infections dues a neisseria gonorrhoeae
GB1553664A (en) * 1975-06-12 1979-09-26 Unilever Ltd Antigenic compositions
US4136167A (en) * 1975-06-12 1979-01-23 Internationale Octrooi Maatschappij "Octropa" B.V. Process for reducing the incidence of neonatal diarrhoea in pigs
US4237115A (en) * 1977-11-23 1980-12-02 Bactex, Inc. Method of immunization against enterotoxogenic infection by Escherichia coli
US4336336A (en) * 1979-01-12 1982-06-22 President And Fellows Of Harvard College Fused gene and method of making and using same
FR2466251B1 (fr) * 1979-10-03 1983-03-18 Agronomique Inst Nat Rech Vaccin animal anticolibacillaire, obtention et application
US4311797A (en) * 1979-09-18 1982-01-19 University Of Saskatchewan Anucleated live E. coli vaccine
SE8001748L (sv) * 1980-03-05 1981-09-06 Kaellenius Gunilla Kompositioner for terapeutisk eller diagnostisk anvendning jemte forfarande for terapeutik
US4454117A (en) * 1980-09-15 1984-06-12 Bactex, Inc. Immunization against infection by Escherichia coli
GB2094314A (en) * 1981-02-05 1982-09-15 Wellcome Found Recombinant DNA
NZ199866A (en) * 1981-03-09 1984-11-09 Cetus Corp Vaccine for prevention of gastroenteric disease:non-pathogenic strain genetically engineered to comprise genes for adhesin and/or toxoids
US4443431A (en) * 1981-05-27 1984-04-17 The United States Of America As Represented By The Department Of Health And Human Services Neisseria gonorrhoeae vaccine
NZ202203A (en) * 1981-10-19 1986-05-09 Molecular Genetics Inc Producing anti-adhesin antibodies
US4443549A (en) * 1981-10-19 1984-04-17 Molecular Genetics, Inc. Production of monoclonal antibodies against bacterial adhesins
FR2516385A1 (fr) * 1981-11-19 1983-05-20 Merieux Inst Vaccin anti-aphteux et anti-colibacillaire et son procede de preparation
JPS58502181A (ja) * 1982-01-18 1983-12-22 サンド・アクチエンゲゼルシヤフト 新規プラスミドと細菌株並びにその製造法
EP0089940A1 (de) * 1982-03-23 1983-09-28 BioCarp AB Oligosaccharide umfassende Zusammensetzung für therapeutische oder diagnostische Verwendung
US4597967A (en) * 1982-07-27 1986-07-01 The University Of Tennessee Research Corp. Synthetic polypeptide fragments
US4521334A (en) * 1982-07-27 1985-06-04 The University Of Tennesse Research Corporation Synthetic polypeptide fragments
NZ205392A (en) * 1982-09-02 1987-03-06 Unilever Plc Preparation of immunoglobulins against e.coli pili
US4652448A (en) * 1982-10-07 1987-03-24 Molecular Genetics, Inc. Use of monoclonal antibodies against bacterial adhesins
US4736017A (en) * 1984-04-30 1988-04-05 The Board Of Trustees Of The Leland Stanford Junior University Chemically defined vaccine against urinary infections
US4801690A (en) * 1986-03-24 1989-01-31 Bactex, Inc. Novel lectins derived from bacterial pili
US4786592A (en) * 1986-06-18 1988-11-22 Scripps Clinic And Research Foundation Neisseria gonorrhoeae lectin useful as a vaccine and diagnostic marker and means for producing this lectin

Also Published As

Publication number Publication date
WO1985005037A1 (en) 1985-11-21
DE3587468D1 (de) 1993-08-26
FI860015A0 (fi) 1986-01-02
FI93310C (fi) 1995-03-27
DK219084D0 (da) 1984-05-02
IE851102L (en) 1985-11-02
EP0179887B1 (de) 1993-07-21
DK609985A (da) 1985-12-30
KR860700090A (ko) 1986-03-31
JPH09183791A (ja) 1997-07-15
US5804198A (en) 1998-09-08
IE59826B1 (en) 1994-04-06
US6291649B1 (en) 2001-09-18
FI860015L (fi) 1986-01-02
US4795803A (en) 1989-01-03
KR950000688B1 (ko) 1995-01-27
DK171258B1 (da) 1996-08-12
AU4299485A (en) 1985-11-28
DK609985D0 (da) 1985-12-30
FI93310B (fi) 1994-12-15
RU1787165C (ru) 1993-01-07
EP0179887A1 (de) 1986-05-07
CA1340847C (en) 1999-12-14
JP2974028B2 (ja) 1999-11-08
AU593770B2 (en) 1990-02-22
JPS62501355A (ja) 1987-06-04
DE3587468T2 (de) 1993-12-02

Similar Documents

Publication Publication Date Title
ATE91629T1 (de) Adhesin-antigene, antikoerper und dns-fragmente die das antigen kodieren, verfahren und mittel zur diagnose und immunisierung, usw.
PT85995A (en) Process for preparing a chimeric antibody with specifity to human tumor antigen
ATE85080T1 (de) Menschlicher transformationswachstumsfaktor und vorlaeufer oder fragment hiervon, zellen, dna, vektoren und verfahren zu ihrer herstellung, zusammensetzungen und produkte, die diese enthalten, sowie davon abgeleitete antikoerper und diagnostizierverfahren.
ES8705975A1 (es) Un metodo de deteccion o localizacion de celulas de carcinoma humano.
ES530853A0 (es) Un metodo para separar una toxina bacteriana de una muestra biologica
HUT50048A (en) Process for producing streptococcus protein antigen and pharmaceutical compositions comprising same
ATE176156T1 (de) Menschliches intra-akrosomales spermaantigen zur verwendung in einem empfängnisverhütungsimpfstoff
ATE14899T1 (de) Hybridzellinie zur herstellung monoklonaler antikoerper gegen ein menschliches monozytantigen, antikoerper und verfahren.
NO965239D0 (no) Monoklonalt antistoff mot CD44v6
KR910016346A (ko) 광견병 바이러스에 대한 사람 모노클로날 항체, 이의 제조방법 및 용도
NL300020I2 (nl) Produktie van virus-antigenen.
Aune et al. Identification and initial characterization of a nonspecific suppressor factor (macrophage-SF) produced by soluble immune response suppressor (SIRS)-treated macrophages.
AU564575B2 (en) Polyvalent endotoxin specific antibodies
NO861577L (no) Antigen, antistoff og fremgangsmaate for dets fremstilling og anvendelse derav for diagnostisering.
KR890002402A (ko) 인간의 유두종바이러스형 41, 이의 dna 및 이로부터 코드화된 단백질
Kurup Murine monoclonal antibodies binding to the specific antigens of Aspergillus fumigatus associated with allergic bronchopulmonary aspergillosis
ATE58397T1 (de) Monoklonaler antikoerper geeignet zur spezifischen unterscheidung von humanen hepatokarzinomzellen.
EP0232706A3 (de) Blutgruppe-Antigen-Platte
ATE106945T1 (de) Methoden und materialien für die hiv-erkennung und therapie.
AU2613588A (en) Method and compositions relating to regression-associated antigens
GB1378103A (en) Serological reagent and test for neisseria gonorrhoeae antibodies
AU7144787A (en) Tumor-associated antigen (mol wt 68,000-48000; 40,000-80000; 28000-32000; 16000-19000)
NO20022276D0 (no) Human neurokinin-B-forlöper fra placenta
STRAIN et al. EQUINE STRANGLES VACCINE AND THE METHOD OF PREPARING AND USING THE SAME
JPS6490198A (en) Monoclonal antibody, its production and reagent consisting thereof for detecting virus

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EELA Cancelled due to lapse of time