DK609985A - Adhesin-antigener, antistoffer mod disse og dna-fragmenter, som indkoder antigenerne - Google Patents

Adhesin-antigener, antistoffer mod disse og dna-fragmenter, som indkoder antigenerne Download PDF

Info

Publication number
DK609985A
DK609985A DK609985A DK609985A DK609985A DK 609985 A DK609985 A DK 609985A DK 609985 A DK609985 A DK 609985A DK 609985 A DK609985 A DK 609985A DK 609985 A DK609985 A DK 609985A
Authority
DK
Denmark
Prior art keywords
antigenes
adhesin
antibodies against
encod
dna fragments
Prior art date
Application number
DK609985A
Other languages
English (en)
Other versions
DK171258B1 (da
DK609985D0 (da
Inventor
Frederik Carl Peter Lindberg
Bjoern Olof Lund
Britt Monika Baaga
Mari Elisabet Norgren
Mikael Goeransson
Bernt Eric Anund Uhlin
Jan Staffan Normark
David Lee Lark
Original Assignee
Syn Tek Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syn Tek Ab filed Critical Syn Tek Ab
Priority to DK609985A priority Critical patent/DK171258B1/da
Publication of DK609985D0 publication Critical patent/DK609985D0/da
Publication of DK609985A publication Critical patent/DK609985A/da
Application granted granted Critical
Publication of DK171258B1 publication Critical patent/DK171258B1/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/025Enterobacteriales, e.g. Enterobacter
    • A61K39/0258Escherichia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/21Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pseudomonadaceae (F)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/22Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/235Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bordetella (G)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/245Escherichia (G)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/305Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
    • C07K14/31Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/33Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/40Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/82Subcellular parts of microorganisms
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/806Antigenic peptides or proteins
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/82Proteins from microorganisms
    • Y10S530/825Bacteria

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Mycology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
DK609985A 1984-05-02 1985-12-30 Antigent præparat indeholdende en determinant fra et adhesin-polypeptid, fremgangsmåder til fremstilling af deteminanten og adhesin-polypeptidet, anvendelser af determinanten og adhesin-polypeptidet, vaccine indeholdende determinanten, fremgangsmåde til fremstilling af vaccinen, antistof rettet mod determinanten, fremgangsmåde til fremstilling af antistoffet, præparatet til passiv immunisering DK171258B1 (da)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DK609985A DK171258B1 (da) 1984-05-02 1985-12-30 Antigent præparat indeholdende en determinant fra et adhesin-polypeptid, fremgangsmåder til fremstilling af deteminanten og adhesin-polypeptidet, anvendelser af determinanten og adhesin-polypeptidet, vaccine indeholdende determinanten, fremgangsmåde til fremstilling af vaccinen, antistof rettet mod determinanten, fremgangsmåde til fremstilling af antistoffet, præparatet til passiv immunisering

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
DK219084 1984-05-02
DK2190/84A DK219084D0 (da) 1984-05-02 1984-05-02 Antigen
DK8500045 1985-05-02
PCT/DK1985/000045 WO1985005037A1 (en) 1984-05-02 1985-05-02 Adhesin antigens, antibodies and dna fragment encoding the antigen, methods and means for diagnosis and immunization etc.
DK609985A DK171258B1 (da) 1984-05-02 1985-12-30 Antigent præparat indeholdende en determinant fra et adhesin-polypeptid, fremgangsmåder til fremstilling af deteminanten og adhesin-polypeptidet, anvendelser af determinanten og adhesin-polypeptidet, vaccine indeholdende determinanten, fremgangsmåde til fremstilling af vaccinen, antistof rettet mod determinanten, fremgangsmåde til fremstilling af antistoffet, præparatet til passiv immunisering
DK609985 1985-12-30

Publications (3)

Publication Number Publication Date
DK609985D0 DK609985D0 (da) 1985-12-30
DK609985A true DK609985A (da) 1985-12-30
DK171258B1 DK171258B1 (da) 1996-08-12

Family

ID=8110676

Family Applications (2)

Application Number Title Priority Date Filing Date
DK2190/84A DK219084D0 (da) 1984-02-02 1984-05-02 Antigen
DK609985A DK171258B1 (da) 1984-05-02 1985-12-30 Antigent præparat indeholdende en determinant fra et adhesin-polypeptid, fremgangsmåder til fremstilling af deteminanten og adhesin-polypeptidet, anvendelser af determinanten og adhesin-polypeptidet, vaccine indeholdende determinanten, fremgangsmåde til fremstilling af vaccinen, antistof rettet mod determinanten, fremgangsmåde til fremstilling af antistoffet, præparatet til passiv immunisering

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK2190/84A DK219084D0 (da) 1984-02-02 1984-05-02 Antigen

Country Status (13)

Country Link
US (3) US4795803A (da)
EP (1) EP0179887B1 (da)
JP (2) JP2974028B2 (da)
KR (1) KR950000688B1 (da)
AT (1) ATE91629T1 (da)
AU (1) AU593770B2 (da)
CA (1) CA1340847C (da)
DE (1) DE3587468T2 (da)
DK (2) DK219084D0 (da)
FI (1) FI93310C (da)
IE (1) IE59826B1 (da)
RU (1) RU1787165C (da)
WO (1) WO1985005037A1 (da)

Families Citing this family (58)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4736017A (en) * 1984-04-30 1988-04-05 The Board Of Trustees Of The Leland Stanford Junior University Chemically defined vaccine against urinary infections
US4584195A (en) * 1984-06-21 1986-04-22 The Board Of Trustees Of The Leland Stanford Junior University Broad spectrum vaccine against gonorrhea
US4740585A (en) * 1984-07-30 1988-04-26 The Board Of Trustees Of The Leland Stanford Junior University Synthetic vaccine against urinary infections
JPS62500933A (ja) * 1984-10-31 1987-04-16 コモンウエルス サイエンテイフイツク アンド インダストリアル リサ−チ オ−ガニゼ−シヨン 改良された抗原製剤
US5288617A (en) * 1984-10-31 1994-02-22 Commonwealth Scientific And Industrial Research Organization Method of producing an antigenic preparation
IL78775A (en) * 1985-05-15 1992-06-21 Biotech Australia Pty Ltd Oral vaccines
DE3689713T2 (de) * 1985-08-01 1994-07-07 Miles Inc Schützende Antikörper gegen serotypische Determinanten von flagellären Antigenen.
US4900659A (en) * 1986-01-30 1990-02-13 Enzo Biochem, Inc. Nucleotide sequence composition and method for detection of Neisseria gonorrhoeae and method for screening for a nucleotide sequence that is specific for a genetically distinct group
US4801690A (en) * 1986-03-24 1989-01-31 Bactex, Inc. Novel lectins derived from bacterial pili
SE8601940D0 (sv) * 1986-04-25 1986-04-25 Kabigen Ab Preparation of fused proteins, antibodies and processes therefor
US4786592A (en) * 1986-06-18 1988-11-22 Scripps Clinic And Research Foundation Neisseria gonorrhoeae lectin useful as a vaccine and diagnostic marker and means for producing this lectin
US7087742B1 (en) 1986-11-24 2006-08-08 Gen-Probe Incorporated Oligonucleotide probes for the detection and/or quantitation of non-viral organisms
US7138516B1 (en) 1986-11-24 2006-11-21 Gen-Probe Incorporated Oligonucleotide probes for the detection and/or quantitation of non-viral organisms
US5036003A (en) * 1987-08-21 1991-07-30 Monsanto Company Antibodies to VPF
AU601510B2 (en) * 1987-11-06 1990-09-13 Immunomed Corporation Preparation of bacterium pili subunits and vaccines containing pili subunits
SE8801894D0 (sv) * 1988-05-20 1988-05-20 Alfa Laval Agri Int Fibronektinbindande protein
US5055455A (en) 1988-09-28 1991-10-08 Brigham And Women's Hospital Capsular polysaccharide adhesin antigen, preparation, purification and use
US7172863B1 (en) 1988-12-09 2007-02-06 Gen-Probe Incorporated Nucleic acid probes and methods for detecting Neisseria gonorrhoeae
CA1340530C (en) * 1989-04-28 1999-05-04 Kok Kheong Lee Synthetic pseudomonas aeruginosa pilin peptide and related vaccines and diagnostics
SE8901687D0 (sv) * 1989-05-11 1989-05-11 Alfa Laval Agri Int Fibronectin binding protein as well as its preparation
US5202113A (en) * 1990-04-30 1993-04-13 The United States Of America As Represented By The Department Of Health And Human Services Plaque-inhibiting protein from bacteroides loeschei and methods for using the same
DK0553113T3 (da) * 1990-08-02 1999-08-09 Antex Biolog Inc Adhæsionsreceptorer for patogene eller opportunistiske mikroorganismer
US5440014A (en) * 1990-08-10 1995-08-08 H+E,Uml/Oo/ K; Magnus Fibronectin binding peptide
JPH06504670A (ja) * 1990-12-21 1994-06-02 マイクロカーブ インコーポレイティド 微生物に関する脂質レセプター及び対応の付着因子、付着因子をコードするdna配列、並びにそれらの利用方法
US5843463A (en) * 1990-12-21 1998-12-01 Antexbiologics, Inc. Adhesin-oligosaccharide conjugate vaccine for Haemophilus influenzae
US5834591A (en) * 1991-01-31 1998-11-10 Washington University Polypeptides and antibodies useful for the diagnosis and treatment of pathogenic neisseria and other microorganisms having type 4 pilin
US5980908A (en) * 1991-12-05 1999-11-09 Alfa Laval Ab Bacterial cell surface protein with fibronectin, fibrinogen, collagen and laminin binding ability, process for the manufacture of the protein and prophylactic treatment
AU662783B2 (en) * 1992-01-08 1995-09-14 De Staat Der Nederlanden Vertegenwoordigd Door De Minister Van Welzijn, Volksgezonheid En Cultuur Whooping cough vaccine
DK0699076T3 (da) * 1993-05-18 2003-03-03 Univ Ohio State Res Found Vaccine mod mellemørebetændelse
US5648240A (en) * 1994-05-24 1997-07-15 Texas A&M University MHC II analog from Staphylococcus aureus
WO1996000233A1 (en) * 1994-06-24 1996-01-04 Children's Hospital And Medical Center Escherichia coli o157:h7 epithelial adhesin
DE19534579C2 (de) * 1995-09-18 2000-06-08 Max Planck Gesellschaft Nucleinsäure-Moleküle codierend Proteine, die die Adhäsion von Neisseria-Zellen an humane Zellen vermitteln
US6872398B2 (en) * 1995-12-22 2005-03-29 The United States Of America As Represented By The Secretary Of The Army Conjugate vaccine against gram-negative bacterial infections
ES2281914T3 (es) * 1996-06-10 2007-10-01 Thomas Boren Antigeno del grupo de union a adhesina de helicobacter pylori.
AU1979599A (en) * 1998-01-14 1999-08-02 Chiron S.P.A. (neisseria meningitidis) antigens
US7252828B2 (en) 1998-07-15 2007-08-07 The Brigham And Women's Hospital, Inc. Polysaccharide vaccine for staphylococcal infections
US6692739B1 (en) 1998-08-31 2004-02-17 Inhibitex, Inc. Staphylococcal immunotherapeutics via donor selection and donor stimulation
WO2000012132A1 (en) * 1998-08-31 2000-03-09 Inhibitex, Inc. Staphylococcal immunotherapeutics via donor selection and donor stimulation
US20040001863A1 (en) * 1998-12-03 2004-01-01 Shau-Chi Chi Immortal cell line derived from grouper Epinephelus coioides and its applications therein
GB9924351D0 (en) * 1999-10-14 1999-12-15 Brennan Frank Immunomodulation methods and compositions
EP1248646B1 (en) * 1999-12-21 2008-02-13 Merial Compositions and vaccines containing antigen(s) of cryptosporidium parvum and of another enteric pathogen
US7939087B2 (en) * 2000-10-27 2011-05-10 Novartis Vaccines And Diagnostics, Inc. Nucleic acids and proteins from Streptococcus groups A & B
WO2002072600A2 (en) 2001-01-26 2002-09-19 Inhibitex, Inc. Monoclonal antibodies to the clfa protein and method of use in treating or preventing infections
US7396822B2 (en) 2001-05-24 2008-07-08 Vaxiion Therapeutics, Inc. Immunogenic minicells and methods of use
US20030194798A1 (en) 2001-05-24 2003-10-16 Surber Mark W. Minicell compositions and methods
US7132101B2 (en) * 2002-02-27 2006-11-07 Duquesne University Of The Holy Ghost Compositions and methods for eliciting an immune response to gram-negative bacterial infections
AU2003256329A1 (en) * 2002-06-27 2004-01-19 University Of Washington Use of adhesion molecules as bond stress-enhanced nanoscale binding switches
WO2004043407A2 (en) 2002-11-12 2004-05-27 The Brigham And Women's Hospital, Inc. Methods and products for treating staphylococcal infections
PT1565478T (pt) 2002-11-12 2017-11-14 The Brigham And Women`S Hospital Inc Vacina de polissacáridos para infeções estafilocócicas
US20060002956A1 (en) * 2004-04-05 2006-01-05 Surber Mark W Minicells as vaccines
EP2468769A1 (en) 2004-04-21 2012-06-27 The Brigham and Women's Hospital, Inc. Poly-N-acetyl glucosamine (PNAG/DPNAG)-binding peptides and methods of use thereof
US7585236B2 (en) * 2006-08-02 2009-09-08 Wilson Sporting Goods Co. Game ball having optimally positioned grooves and/or ridges
US8251846B2 (en) * 2006-08-02 2012-08-28 Wilson Sporting Goods Co. Game ball having optimally positioned grooves
US7686713B2 (en) * 2007-04-11 2010-03-30 Wilson Sporting Goods Co. Racquet stringing machine
JP2010524508A (ja) * 2007-04-27 2010-07-22 ダウ グローバル テクノロジーズ インコーポレイティド 可溶性組換え二十面体ウイルス様粒子の生産及びインビボ組織化の改善
KR20150041178A (ko) 2008-07-21 2015-04-15 더 브리검 앤드 우먼즈 하스피털, 인크. 합성 베타-1,6 글루코사민 올리고당에 관한 방법 및 조성물
EP2675474B1 (en) 2011-02-15 2019-01-16 Vaxiion Therapeutics, LLC Therapeutic compositions and methods for antibody and fc-containing targeting molecule-based targeted delivery of bioactive molecules by bacterial minicells
US12397014B2 (en) 2019-02-05 2025-08-26 The Brigham And Women's Hospital, Inc. Polysaccharide compositions for use in treating filariasis

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU853813B (en) 1913-03-31 1914-04-11 George Reid Angus Improvements in the manufacture of filter frames for beer and other liquids
GB1472624A (en) * 1974-09-02 1977-05-04 Canadian Patents Dev Enteric disease vaccine
GB1549345A (en) * 1975-04-25 1979-08-08 Bactex Inc Gonococcal pili processes for the preparation thereof and the use thereof
US4461838A (en) * 1975-04-25 1984-07-24 Bactex, Inc. Gonococcal Pili processes for the preparation thereof and the use thereof for the detection of and prevention of infections caused by Neisseria gonorrhoeae
GB1553664A (en) * 1975-06-12 1979-09-26 Unilever Ltd Antigenic compositions
US4136167A (en) * 1975-06-12 1979-01-23 Internationale Octrooi Maatschappij "Octropa" B.V. Process for reducing the incidence of neonatal diarrhoea in pigs
US4237115A (en) * 1977-11-23 1980-12-02 Bactex, Inc. Method of immunization against enterotoxogenic infection by Escherichia coli
US4336336A (en) * 1979-01-12 1982-06-22 President And Fellows Of Harvard College Fused gene and method of making and using same
FR2466251B1 (fr) * 1979-10-03 1983-03-18 Agronomique Inst Nat Rech Vaccin animal anticolibacillaire, obtention et application
US4311797A (en) * 1979-09-18 1982-01-19 University Of Saskatchewan Anucleated live E. coli vaccine
SE8001748L (sv) * 1980-03-05 1981-09-06 Kaellenius Gunilla Kompositioner for terapeutisk eller diagnostisk anvendning jemte forfarande for terapeutik
US4454117A (en) * 1980-09-15 1984-06-12 Bactex, Inc. Immunization against infection by Escherichia coli
GB2094314A (en) * 1981-02-05 1982-09-15 Wellcome Found Recombinant DNA
WO1982003088A1 (en) * 1981-03-09 1982-09-16 Corp Cetus Vaccines
US4443431A (en) * 1981-05-27 1984-04-17 The United States Of America As Represented By The Department Of Health And Human Services Neisseria gonorrhoeae vaccine
US4443549A (en) * 1981-10-19 1984-04-17 Molecular Genetics, Inc. Production of monoclonal antibodies against bacterial adhesins
NZ202203A (en) * 1981-10-19 1986-05-09 Molecular Genetics Inc Producing anti-adhesin antibodies
FR2516385A1 (fr) * 1981-11-19 1983-05-20 Merieux Inst Vaccin anti-aphteux et anti-colibacillaire et son procede de preparation
JPS58502181A (ja) * 1982-01-18 1983-12-22 サンド・アクチエンゲゼルシヤフト 新規プラスミドと細菌株並びにその製造法
DK131083A (da) * 1982-03-23 1983-09-24 Svenska Sockerfabriks Ab Fremgangsmaade til fremstilling af terapeutiske eller diagnostiske praeparater
US4521334A (en) * 1982-07-27 1985-06-04 The University Of Tennesse Research Corporation Synthetic polypeptide fragments
US4597967A (en) * 1982-07-27 1986-07-01 The University Of Tennessee Research Corp. Synthetic polypeptide fragments
NZ205392A (en) * 1982-09-02 1987-03-06 Unilever Plc Preparation of immunoglobulins against e.coli pili
US4652448A (en) * 1982-10-07 1987-03-24 Molecular Genetics, Inc. Use of monoclonal antibodies against bacterial adhesins
US4736017A (en) * 1984-04-30 1988-04-05 The Board Of Trustees Of The Leland Stanford Junior University Chemically defined vaccine against urinary infections
US4801690A (en) * 1986-03-24 1989-01-31 Bactex, Inc. Novel lectins derived from bacterial pili
US4786592A (en) * 1986-06-18 1988-11-22 Scripps Clinic And Research Foundation Neisseria gonorrhoeae lectin useful as a vaccine and diagnostic marker and means for producing this lectin

Also Published As

Publication number Publication date
IE59826B1 (en) 1994-04-06
FI93310C (fi) 1995-03-27
IE851102L (en) 1985-11-02
EP0179887B1 (en) 1993-07-21
DE3587468D1 (de) 1993-08-26
US6291649B1 (en) 2001-09-18
RU1787165C (ru) 1993-01-07
WO1985005037A1 (en) 1985-11-21
US4795803A (en) 1989-01-03
JPH09183791A (ja) 1997-07-15
FI93310B (fi) 1994-12-15
DK171258B1 (da) 1996-08-12
DK609985D0 (da) 1985-12-30
AU4299485A (en) 1985-11-28
KR950000688B1 (ko) 1995-01-27
US5804198A (en) 1998-09-08
FI860015L (fi) 1986-01-02
CA1340847C (en) 1999-12-14
AU593770B2 (en) 1990-02-22
FI860015A0 (fi) 1986-01-02
DE3587468T2 (de) 1993-12-02
ATE91629T1 (de) 1993-08-15
JPS62501355A (ja) 1987-06-04
KR860700090A (ko) 1986-03-31
JP2974028B2 (ja) 1999-11-08
EP0179887A1 (en) 1986-05-07
DK219084D0 (da) 1984-05-02

Similar Documents

Publication Publication Date Title
DK609985A (da) Adhesin-antigener, antistoffer mod disse og dna-fragmenter, som indkoder antigenerne
ATE9062T1 (de) Zusammensetzung fuer die therapeutische oder diagnostische verwendung.
ES490944A0 (es) Un metodo para la preparacion de un anticuerpo monoclonico, de fijacion de complemento
DK154087C (da) Monoklonalt antistof, fremstilling heraf, hybrodimacellelinie til anvendelse ved fremstilling heraf, fremgangsmaade til anvendelse heraf samt diagnostisk praeparat indeholdende antistoffet
DE3587507D1 (de) Monoklonale antikoerper gegen alveolares oberflaechenaktives protein.
DK0419387T3 (da) Hidtil ukendte hydrofile derivater, terapeutisk og diagnostisk anvendelse, diagnostiske eller terapeutiske kit og immunologiske reagenser
ES2130121T3 (es) Antigeno intra-acrosomico de esperma humano para uso en una vacuna anticonceptiva.
DK304087D0 (da) Humant monoklonalt antistof mod lumfadenopati-associeret virus
DK392387D0 (da) Monoklonalt antistrof til diagnostisk anvendelse og fremgangsmaade til fremstilling af et saadan antistof
ES505364A0 (es) Procedimiento para la fabricacion de isomaltulosa (6-0-z- glucopiranosido-d-fructosa) con la ayuda de celulas bacte- rianas inmovilizadas
DE69628298D1 (de) Immunovektoren zum transport in die zelle und den zellkern
NO174855C (no) Monoklonalt antistoff og cellelinje som produserer dette
ATE137864T1 (de) Immunobestimmung von menschlichem osteocalcin, reagenz und satz dafür
ES8604693A1 (es) Un metodo para detectar un anticuerpo o un antigeno contenido en una muestra de fluido de origen biologico.
ES2056919T3 (es) Anticuerpo monoclonal especifico para la fosfolipasa a2 pancreatica humana.
NO885113D0 (no) Monoklonalt antistoff som gjenkjenner alfa-2-3-bindinger.
DE3885975D1 (de) Monoklonale Antikörper gegen menschliche alpha-Atrialnatriüretic-Polypeptide und entsprechende Hybridome, deren Herstellung und Verwendung.
JPS55141452A (en) Synthetic polypeptide
NO852058L (no) Fremgangsmaate og middel for bestemmelse av atl virus antistoffer.
GB916455A (en) Non-toxic antigens and process for producing same
DE68926294D1 (de) Antigen gegen diabetes
NO174632C (no) Monoklonale antistoffer som er i stand til å gjenkjenne gangliosider GQ1B og GT1A og en hyberidom som produserer disse antistoffene
RU93020806A (ru) Способ получения антибруцеллезной сыворотки
DK340887A (da) Antigenisk peptid isoleret fra 28 kd proteinet fras. mansoni og fremgangsmaade til dets isolering, monoklonale antistoffer, der genkender mindst en epitop af peptidet og dets anvendelse til syntese af antistoffer
ES8801959A1 (es) Un procedimiento para ensayos de sangre humana respecto de la presencia de anticuerpos frente al agente etiologico viral de sida

Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PUP Patent expired