ATE92032T1 - Arylessigsaeuremonoester, deren herstellung und verwendung. - Google Patents
Arylessigsaeuremonoester, deren herstellung und verwendung.Info
- Publication number
- ATE92032T1 ATE92032T1 AT89313075T AT89313075T ATE92032T1 AT E92032 T1 ATE92032 T1 AT E92032T1 AT 89313075 T AT89313075 T AT 89313075T AT 89313075 T AT89313075 T AT 89313075T AT E92032 T1 ATE92032 T1 AT E92032T1
- Authority
- AT
- Austria
- Prior art keywords
- hydrogen
- optionally substituted
- arylacetic acid
- methyl
- protecting group
- Prior art date
Links
- 239000002253 acid Substances 0.000 title abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 6
- 239000001257 hydrogen Substances 0.000 abstract 6
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 5
- 150000002148 esters Chemical class 0.000 abstract 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
- 125000006239 protecting group Chemical group 0.000 abstract 2
- UUFQTNFCRMXOAE-UHFFFAOYSA-N 1-methylmethylene Chemical compound C[CH] UUFQTNFCRMXOAE-UHFFFAOYSA-N 0.000 abstract 1
- 101100167062 Caenorhabditis elegans chch-3 gene Proteins 0.000 abstract 1
- 150000008065 acid anhydrides Chemical class 0.000 abstract 1
- 125000004450 alkenylene group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 150000002431 hydrogen Chemical class 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 229930014626 natural product Natural products 0.000 abstract 1
- 230000003287 optical effect Effects 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 125000000547 substituted alkyl group Chemical group 0.000 abstract 1
- 125000003107 substituted aryl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/74—Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring
- C07C69/753—Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring of polycyclic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/08—Preparation of carboxylic acid esters by reacting carboxylic acids or symmetrical anhydrides with the hydroxy or O-metal group of organic compounds
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP31573088 | 1988-12-14 | ||
| EP89313075A EP0373931B1 (de) | 1988-12-14 | 1989-12-14 | Arylessigsäuremonoester, deren Herstellung und Verwendung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE92032T1 true ATE92032T1 (de) | 1993-08-15 |
Family
ID=18068843
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT89313075T ATE92032T1 (de) | 1988-12-14 | 1989-12-14 | Arylessigsaeuremonoester, deren herstellung und verwendung. |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US5117039A (de) |
| EP (1) | EP0373931B1 (de) |
| KR (1) | KR0144685B1 (de) |
| AT (1) | ATE92032T1 (de) |
| DE (1) | DE68907873T2 (de) |
| ES (1) | ES2058557T3 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1992022560A1 (fr) * | 1991-06-19 | 1992-12-23 | Shionogi Seiyaku Kabushiki Kaisha | Intermediaire optiquement actif et production de celui-ci |
| US6727277B1 (en) | 2002-11-12 | 2004-04-27 | Kansas State University Research Foundation | Compounds affecting cholesterol absorption |
| WO2011141934A1 (en) | 2010-05-13 | 2011-11-17 | Matrix Laboratories Ltd. | An improved process for the preparation of an intermediate of hmg-coa reductase inhibitors |
| JP6181063B2 (ja) | 2011-11-28 | 2017-08-16 | マイラン ラボラトリーズ リミテッドMylan Laboratories Limited | HMG−CoAレダクターゼ阻害剤の中間体の新規な製造方法 |
| CN103408580B (zh) * | 2013-06-03 | 2014-11-19 | 南京欧信医药技术有限公司 | 一种他汀类药物合成中间体的制备方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT257569B (de) * | 1965-05-06 | 1967-10-10 | Kwizda Fa F Johann | Verfahren zur Herstellung von bicyclischen oder polycyclischen vicinalen Dicarbonsäuren der trans Konfiguration und deren Derivaten |
| CA1278577C (en) * | 1985-11-18 | 1991-01-02 | Tatsuo Tsuri | Bicyclic sulfonamide derivatives |
-
1989
- 1989-12-07 US US07/447,518 patent/US5117039A/en not_active Expired - Fee Related
- 1989-12-14 AT AT89313075T patent/ATE92032T1/de not_active IP Right Cessation
- 1989-12-14 DE DE89313075T patent/DE68907873T2/de not_active Expired - Fee Related
- 1989-12-14 EP EP89313075A patent/EP0373931B1/de not_active Expired - Lifetime
- 1989-12-14 KR KR1019890018555A patent/KR0144685B1/ko not_active Expired - Fee Related
- 1989-12-14 ES ES89313075T patent/ES2058557T3/es not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP0373931A3 (de) | 1991-05-15 |
| US5117039A (en) | 1992-05-26 |
| KR900009533A (ko) | 1990-07-04 |
| HK1003786A1 (en) | 1998-11-06 |
| DE68907873D1 (de) | 1993-09-02 |
| EP0373931A2 (de) | 1990-06-20 |
| DE68907873T2 (de) | 1993-11-11 |
| ES2058557T3 (es) | 1994-11-01 |
| EP0373931B1 (de) | 1993-07-28 |
| KR0144685B1 (ko) | 1998-07-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |