ATE93628T1 - Peridinin-chlorophyll-komplex als fluoreszierende erkennungszeichen. - Google Patents

Peridinin-chlorophyll-komplex als fluoreszierende erkennungszeichen.

Info

Publication number: ATE93628T1
Authority: AT; Austria
Prior art keywords: pair; peridinin chlorophyll; fluorescent; chlorophyll complex; fluorescent identifier
Prior art date: 1987-10-21

Application number

AT88309940T

Other languages

English (en)

Inventor

Diether J Recktenwald

Original Assignee

Becton Dickinson Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-10-21

Filing date

1988-10-21

Publication date

1993-09-15

1988-10-21 Application filed by Becton Dickinson Co filed Critical Becton Dickinson Co

1993-09-15 Application granted granted Critical

1993-09-15 Publication of ATE93628T1 publication Critical patent/ATE93628T1/de

Links

UYRDHEJRPVSJFM-VSWVFQEASA-N [(1s,3r)-3-hydroxy-4-[(3e,5e,7e,9e,11z)-11-[4-[(e)-2-[(1r,3s,6s)-3-hydroxy-1,5,5-trimethyl-7-oxabicyclo[4.1.0]heptan-6-yl]ethenyl]-5-oxofuran-2-ylidene]-3,10-dimethylundeca-1,3,5,7,9-pentaenylidene]-3,5,5-trimethylcyclohexyl] acetate Chemical compound C[C@@]1(O)C[C@@H](OC(=O)C)CC(C)(C)C1=C=C\C(C)=C\C=C\C=C\C=C(/C)\C=C/1C=C(\C=C\[C@]23[C@@](O2)(C)C[C@@H](O)CC3(C)C)C(=O)O\1 UYRDHEJRPVSJFM-VSWVFQEASA-N 0.000 title 1
229930002875 chlorophyll Natural products 0.000 title 1
235000019804 chlorophyll Nutrition 0.000 title 1
ATNHDLDRLWWWCB-AENOIHSZSA-M chlorophyll a Chemical compound C1([C@@H](C(=O)OC)C(=O)C2=C3C)=C2N2C3=CC(C(CC)=C3C)=[N+]4C3=CC3=C(C=C)C(C)=C5N3[Mg-2]42[N+]2=C1[C@@H](CCC(=O)OC\C=C(/C)CCC[C@H](C)CCC[C@H](C)CCCC(C)C)[C@H](C)C2=C5 ATNHDLDRLWWWCB-AENOIHSZSA-M 0.000 title 1
UTIQDNPUHSAVDN-UHFFFAOYSA-N peridinin Natural products CC(=O)OC1CC(C)(C)C(=C=CC(=CC=CC=CC=C2/OC(=O)C(=C2)C=CC34OC3(C)CC(O)CC4(C)C)C)C(C)(O)C1 UTIQDNPUHSAVDN-UHFFFAOYSA-N 0.000 title 1
238000003556 assay Methods 0.000 abstract 2
239000003153 chemical reaction reagent Substances 0.000 abstract 1
230000000295 complement effect Effects 0.000 abstract 1
239000007850 fluorescent dye Substances 0.000 abstract 1
239000003446 ligand Substances 0.000 abstract 1
230000009870 specific binding Effects 0.000 abstract 1

Classifications

- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G01N33/532—Production of labelled immunochemicals
- G01N33/533—Production of labelled immunochemicals with fluorescent label
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/968—High energy substrates, e.g. fluorescent, chemiluminescent, radioactive
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/80—Fluorescent dyes, e.g. rhodamine
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/802—Chromogenic or luminescent peptides

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Immunology (AREA)
Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Biomedical Technology (AREA)
Chemical & Material Sciences (AREA)
Hematology (AREA)
Urology & Nephrology (AREA)
Food Science & Technology (AREA)
General Physics & Mathematics (AREA)
Cell Biology (AREA)
Biotechnology (AREA)
Medicinal Chemistry (AREA)
Physics & Mathematics (AREA)
Analytical Chemistry (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
Microbiology (AREA)
Pathology (AREA)
Investigating Or Analysing Biological Materials (AREA)
Plural Heterocyclic Compounds (AREA)
Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Medicines Containing Plant Substances (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

AT88309940T 1987-10-21 1988-10-21 Peridinin-chlorophyll-komplex als fluoreszierende erkennungszeichen. ATE93628T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US07/111,209 US4876190A (en)	1987-10-21	1987-10-21	Peridinin-chlorophyll complex as fluorescent label
EP88309940A EP0314406B1 (de)	1987-10-21	1988-10-21	Peridinin-Chlorophyll-Komplex als fluoreszierende Erkennungszeichen

Publications (1)

Publication Number	Publication Date
ATE93628T1 true ATE93628T1 (de)	1993-09-15

Family

ID=22337182

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT88309940T ATE93628T1 (de)	1987-10-21	1988-10-21	Peridinin-chlorophyll-komplex als fluoreszierende erkennungszeichen.

Country Status (6)

Country	Link
US (1)	US4876190A (de)
EP (1)	EP0314406B1 (de)
JP (1)	JPH0614043B2 (de)
AT (1)	ATE93628T1 (de)
DE (1)	DE3883478T2 (de)
ES (1)	ES2059533T3 (de)

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US5224058A (en) *	1990-05-01	1993-06-29	Becton, Dickinson And Company	Method for data transformation
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EP0916085A4 (de) *	1996-08-02	2005-12-07	Univ California	Verwendung von phytofluors als fluoreszenzmarker
US6544797B1 (en)	1997-04-09	2003-04-08	Biosite Diagnostics, Inc.	Compositions and methods for inhibiting light-induced inactivation of biological reagents
US7745142B2 (en)	1997-09-15	2010-06-29	Molecular Devices Corporation	Molecular modification assays
US7632651B2 (en)	1997-09-15	2009-12-15	Mds Analytical Technologies (Us) Inc.	Molecular modification assays
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US6133429A (en) *	1997-10-03	2000-10-17	Becton Dickinson And Company	Chromophores useful for the preparation of novel tandem conjugates
US6821740B2 (en) *	1998-02-25	2004-11-23	Becton, Dickinson And Company	Flow cytometric methods for the concurrent detection of discrete functional conformations of PRB in single cells
US6200766B1 (en)	1998-12-03	2001-03-13	Becton Dickinson And Company	Methods and reagents for quantitation of HLA-DR expression on peripheral blood cells
US6423505B1 (en)	1998-12-03	2002-07-23	Becton Dickinson And Company	Methods and reagents for quantitation of HLA-DR and CD11b expression on peripheral blood cells
US6197520B1 (en) *	1999-08-13	2001-03-06	University Of Utah Research Foundation	Solution-based color compensation adjusted for temperature and electronic gains
US8048659B1 (en)	1999-10-08	2011-11-01	Leif Robert C	Conjugated polymer tag complexes
US20050032132A1 (en) *	2001-07-25	2005-02-10	Hisae Niki	Cancer diagnostics
WO2003019155A1 (fr) *	2001-08-27	2003-03-06	Asahi Kasei Kabushiki Kaisha	Procede d'analyse de l'interaction entre materiau et substance biologique
JP5805358B2 (ja) *	2005-02-02	2015-11-04	ブルース・ミルネ・ホール	特異抗原に活性化したｃｄ４＋、ｃｄ２５＋ｔ細胞
WO2007055905A2 (en)	2005-11-07	2007-05-18	Amorcyte, Inc.	Compositions and methods of vascular injury repair
EP2052076A4 (de)	2006-08-02	2010-07-14	Newsouth Innovations Pty Ltd	Verfahren zur identifizierung von gegen ein antigen aktivierten, cd8 exprimierenden cd4+cd25+-t-zellen
EP2155782A2 (de) *	2007-03-26	2010-02-24	Dako Denmark A/S	Mhc-peptid-komplexe und anwendungen davon bei infektionskrankheiten
WO2009003493A2 (en) *	2007-07-03	2009-01-08	Dako Denmark A/S	Mhc multimers, methods for their generation, labeling and use
US7816135B2 (en)	2007-07-05	2010-10-19	Becton, Dickinson And Company	Method of analyzing lymphocytes
WO2009039854A2 (en)	2007-09-27	2009-04-02	Dako Denmark A/S	Mhc multimers in tuberculosis diagnostics, vaccine and therapeutics
DK2254592T3 (da)	2008-02-28	2019-09-09	Dako Denmark As	MHC-multimerer til Borrelia-diagnostik og sygdom
WO2010009735A2 (en)	2008-07-23	2010-01-28	Dako Denmark A/S	Combinatorial analysis and repair
GB0817244D0 (en) *	2008-09-20	2008-10-29	Univ Cardiff	Use of a protein kinase inhibitor to detect immune cells, such as T cells
US11992518B2 (en)	2008-10-02	2024-05-28	Agilent Technologies, Inc.	Molecular vaccines for infectious disease
WO2010037402A1 (en)	2008-10-02	2010-04-08	Dako Denmark A/S	Molecular vaccines for infectious disease
US8153442B2 (en) *	2009-10-21	2012-04-10	Siemens Healthcare Diagnostics Inc.	Stabilization of signal generation in particles used in assays
JP5709880B2 (ja)	2009-10-23	2015-04-30	アモーサイトインコーポレイテッド	血管の機能不全による進行性心筋傷害治療のための組成物および方法
US9533010B2 (en)	2011-10-31	2017-01-03	Amorcyte, Llc	Compositions and methods for treating progressive myocardial injury due to a vascular insufficiency
GB201205288D0 (en)	2012-03-26	2012-05-09	Protein Technologies Ltd	Peridinin-chlorophyll binding proteins
EP3504316B1 (de)	2016-08-29	2021-06-23	Hackensack University Medical Center	Verfahren zur behandlung einer immunkrankheit durch verringerung der autoreaktivität in einem t-zellkompartiment
EP3555127B1 (de)	2016-12-16	2024-12-18	H. Lundbeck A/S	Wirkstoffe, verwendungen und verfahren
EP3676612A4 (de) *	2017-08-31	2021-05-26	Agilent Technologies, Inc.	Zusammensetzung zur stabilisierung von percp enthaltenden antikörperformulierungen
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WO2020127222A2 (en)	2018-12-17	2020-06-25	Immudex Aps	Panel comprising borrelia mhc multimers
CN114563362B (zh) *	2022-01-29	2022-11-04	大连海事大学	一种船舶压载水微藻含量的检测方法

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US4745285A (en) *	1986-08-21	1988-05-17	Becton Dickinson And Company	Multi-color fluorescence analysis with single wavelength excitation

1987
- 1987-10-21 US US07/111,209 patent/US4876190A/en not_active Expired - Lifetime
1988
- 1988-10-21 AT AT88309940T patent/ATE93628T1/de not_active IP Right Cessation
- 1988-10-21 JP JP63265937A patent/JPH0614043B2/ja not_active Expired - Lifetime
- 1988-10-21 EP EP88309940A patent/EP0314406B1/de not_active Expired - Lifetime
- 1988-10-21 ES ES88309940T patent/ES2059533T3/es not_active Expired - Lifetime
- 1988-10-21 DE DE88309940T patent/DE3883478T2/de not_active Expired - Lifetime

Also Published As

Publication number	Publication date
ES2059533T3 (es)	1994-11-16
JPH0614043B2 (ja)	1994-02-23
JPH01147368A (ja)	1989-06-09
US4876190A (en)	1989-10-24
DE3883478T2 (de)	1994-02-17
EP0314406A1 (de)	1989-05-03
EP0314406B1 (de)	1993-08-25
DE3883478D1 (de)	1993-09-30

Legal Events

Date	Code	Title	Description
1994-02-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
DE3883478D1 (de)	1993-09-30	Peridinin-Chlorophyll-Komplex als fluoreszierende Erkennungszeichen.
EP2186910A3 (de)	2011-04-06	Verfahren und Zusammensetzungen für verbesserte Lumineszenztests unter Verwendung von Mikropartikeln
DE69029016D1 (de)	1996-12-05	Heterogene Immuntests
EP0375422A3 (de)	1991-07-24	Zusammensetzung und Methoden zur Bestimmung der Anwesenheit von Amphetaminen in einer Probe, die in Verdacht steht, Amphetamine und/oder Metamphetamine zu enthalten
GB9824632D0 (en)	1999-01-06	Biological compounds
EP0214847A3 (en)	1988-06-01	Squarate dye conjugate, process for making it and its use in assay methods and kits
CA2099433A1 (en)	1994-01-03	Enhancement of signal in immunoassays using microparticles which contain different detectable substances
KR910005862A (ko)	1991-04-27	신규 친수성 유도체, 진단 또는 치료시 그의 응용 그를 함유하는 진단 또는 치료용 키트 및 면역 시약
GB2233450B (en)	1993-06-30	Detecting or quantifing multiple analytes with luminescent reagents
EP0402846A3 (de)	1992-12-02	Fluoreszenzpolarisationsimmunoassay für Tetrahydrocannabinoide
ATE468533T1 (de)	2010-06-15	Enzym-protein-komplex
DK0487301T3 (da)	2000-09-18	Fremgangsmåde til stabilisering af enzymkonjugater
WO2001016184A3 (en)	2001-06-21	Diagnostic assay for type 2 heparin-induced thrombocytopenia
WO2003106649A3 (en)	2004-12-02	CONJUGATE TEST AND USES THEREOF
GB8927365D0 (en)	1990-01-31	Reagent
CA2132708A1 (en)	1993-09-30	Fluorescence immunoassays using fluorescent dyes free of aggregation and serum binding
ATE19828T1 (de)	1986-05-15	Verbessertes fluoreszierendes immunotestsystem.
FR2582103B1 (fr)	1989-05-05	Procede de determination d'une substance biologique dans un echantillon
GB2200448B (en)	1991-01-16	Targetted liposomes and their use in immunoassay
ES2054686T3 (es)	1994-08-16	Equipo de inmunoensayo.
ATE110469T1 (de)	1994-09-15	Nichttrennender festphasen-enzymtest.
MY106963A (en)	1995-08-30	Agglutination assay.
DK0994121T3 (da)	2007-02-12	Forgrenede peptider i analyser for antistoffer
AU647449B2 (en)	1994-03-24	Method for the immunological determination of ligands
AU1062588A (en)	1988-07-28	Immunoassay utilizing microparticle neutralization