ATE96037T1 - Mehrphasige injizierbare emulsionen. - Google Patents
Mehrphasige injizierbare emulsionen.Info
- Publication number
- ATE96037T1 ATE96037T1 AT90910772T AT90910772T ATE96037T1 AT E96037 T1 ATE96037 T1 AT E96037T1 AT 90910772 T AT90910772 T AT 90910772T AT 90910772 T AT90910772 T AT 90910772T AT E96037 T1 ATE96037 T1 AT E96037T1
- Authority
- AT
- Austria
- Prior art keywords
- pct
- formula
- sec
- active substances
- representing
- Prior art date
Links
- 239000000839 emulsion Substances 0.000 title abstract 2
- 239000013543 active substance Substances 0.000 abstract 2
- 239000000470 constituent Substances 0.000 abstract 2
- 239000012071 phase Substances 0.000 abstract 2
- 239000002671 adjuvant Substances 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 239000008346 aqueous phase Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000001804 emulsifying effect Effects 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/113—Multiple emulsions, e.g. oil-in-water-in-oil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dispersion Chemistry (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Colloid Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8908917A FR2649012B1 (fr) | 1989-07-03 | 1989-07-03 | Emulsions multiphasiques injectables |
| PCT/FR1990/000484 WO1991000106A1 (fr) | 1989-07-03 | 1990-06-29 | Emulsions multiphasiques injectables |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE96037T1 true ATE96037T1 (de) | 1993-11-15 |
Family
ID=9383409
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT90910772T ATE96037T1 (de) | 1989-07-03 | 1990-06-29 | Mehrphasige injizierbare emulsionen. |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US5424067A (de) |
| EP (1) | EP0480981B1 (de) |
| JP (1) | JP2851422B2 (de) |
| AT (1) | ATE96037T1 (de) |
| AU (1) | AU643690B2 (de) |
| BR (1) | BR9007501A (de) |
| DE (1) | DE69004094T2 (de) |
| DK (1) | DK0480981T3 (de) |
| ES (1) | ES2061054T3 (de) |
| FR (1) | FR2649012B1 (de) |
| NZ (1) | NZ234336A (de) |
| WO (1) | WO1991000106A1 (de) |
Families Citing this family (54)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2681246B1 (fr) * | 1991-04-05 | 1995-02-10 | Oreal | Composition cosmetique sous forme d'emulsion triple. |
| CA2083553A1 (en) * | 1991-11-25 | 1993-05-26 | Kuniharu Seki | Immunogen composition |
| FR2702373B1 (fr) * | 1993-03-08 | 1996-06-07 | Rhone Merieux | Emulsions vaccinales fluides eau-dans-l'huile contenant une huile métabolisable. |
| FR2717694B1 (fr) * | 1994-03-22 | 1996-05-03 | Seppic Sa | Une composition comprenant un plasmide recombinant et ses utilisations comme vaccin et médicament. |
| US5690942A (en) † | 1995-06-02 | 1997-11-25 | American Home Products Corporation | Adjuvants for viral vaccines |
| DE69636889T2 (de) * | 1995-11-30 | 2007-12-06 | Nof Corp. | Öladjuvierter Impfstoff und Verfahren zu seiner Herstellung |
| GB9626865D0 (en) * | 1996-12-24 | 1997-02-12 | Cyanamid Websters Pty Limited | Veterinary vaccines |
| AU776364B2 (en) * | 1996-12-24 | 2004-09-09 | Zoetis Services Llc | Veterinary vaccines |
| EP1023083A4 (de) * | 1997-10-17 | 2006-06-14 | Wyeth Corp | Veterinär-impfstoffe |
| US6524592B2 (en) | 1997-10-17 | 2003-02-25 | American Home Products Corporation | Veterinary vaccines |
| AU769539B2 (en) * | 1999-01-29 | 2004-01-29 | Zoetis Services Llc | Adjuvants for use in vaccines |
| FR2800280B1 (fr) * | 1999-10-29 | 2003-09-19 | Seppic Sa | Nouvelle composition vaccinale et utilisation d'agents tensioactifs comme adjuvants d'immunite |
| JP2001131087A (ja) * | 1999-11-05 | 2001-05-15 | Chemo Sero Therapeut Res Inst | オイルアジュバントワクチン |
| US20020058040A1 (en) * | 1999-12-23 | 2002-05-16 | Stephen Grimes | Stable immunogenic composition for frozen storage |
| FR2814956B1 (fr) | 2000-10-06 | 2003-01-24 | Seppic Sa | Nouvelle composition vaccinale, procede pour sa preparation, utilisation comme composition injectale en medecine humaine ou veterinaire et nouveau procede de conservation |
| DK1889630T3 (da) | 2000-10-18 | 2012-03-05 | Glaxosmithkline Biolog Sa | Vacciner omfattende MAGE-antigen koblet til protein D-fragment |
| FR2823119B1 (fr) * | 2001-04-05 | 2004-02-20 | Seppic Sa | Adjuvant d'immunite contenant un cation metallique complexe et vaccin le contenant |
| FR2824279B1 (fr) * | 2001-05-04 | 2004-05-28 | Seppic Sa | Emulsion e/h concentree |
| FR2824269B1 (fr) * | 2001-09-03 | 2012-03-02 | Seppic Sa | Composition adjuvante constituee de 1% a 15% de tensioactifs a hlb global compris entre 5 et 8 et de 85% a 99% de corps gras |
| US20050158329A1 (en) * | 2004-01-21 | 2005-07-21 | Ghosh Swapan K. | Novel phytol derived immunoadjuvants and their use in vaccine formulations |
| GB0409940D0 (en) * | 2004-05-04 | 2004-06-09 | Glaxosmithkline Biolog Sa | Vaccine |
| GB0607088D0 (en) | 2006-04-07 | 2006-05-17 | Glaxosmithkline Biolog Sa | Vaccine |
| BRPI0620460B8 (pt) | 2005-12-22 | 2021-05-25 | Glaxosmithkline Biologicals Sa | uso de composição imunogênica para bebês, e, processo para produzir uma vacina |
| MY148405A (en) | 2006-03-30 | 2013-04-30 | Glaxosmithkline Biolog Sa | Immunogenic composition |
| US20070292521A1 (en) * | 2006-06-20 | 2007-12-20 | Schwitzer Co., Ltd | Oral Encapsulated Preparation for Aquatic Animals |
| KR101378872B1 (ko) | 2006-09-26 | 2014-04-11 | 인펙셔스 디지즈 리서치 인스티튜트 (아이디알아이) | 합성 애주번트를 함유하는 백신 조성물 |
| US20090181078A1 (en) | 2006-09-26 | 2009-07-16 | Infectious Disease Research Institute | Vaccine composition containing synthetic adjuvant |
| BRPI0813644B8 (pt) | 2007-06-26 | 2021-05-25 | Glaxosmithkline Biologicals Sa | composição imunogênica, vacina, processo para fabricar a mesma, e, uso da composição imunogênica ou vacina |
| TWI551295B (zh) | 2008-04-18 | 2016-10-01 | 英特威特國際股份有限公司 | 防備胞內勞森菌(Lawsonia intracellularis)用疫苗 |
| SI2437753T1 (sl) | 2009-06-05 | 2016-12-30 | Infectious Disease Research Institute | Sintetični glukopiranozil-lipidni adjuvansi in cepivni sestavki, ki jih vsebujejo |
| GB0913681D0 (en) | 2009-08-05 | 2009-09-16 | Glaxosmithkline Biolog Sa | Immunogenic composition |
| GB0913680D0 (en) | 2009-08-05 | 2009-09-16 | Glaxosmithkline Biolog Sa | Immunogenic composition |
| EP2353609A1 (de) | 2010-02-04 | 2011-08-10 | Sanofi Pasteur | Immunisierungszusammensetzungen und -verfahren |
| GB201003920D0 (en) | 2010-03-09 | 2010-04-21 | Glaxosmithkline Biolog Sa | Method of treatment |
| AU2012243039B2 (en) | 2011-04-08 | 2017-07-13 | Immune Design Corp. | Immunogenic compositions and methods of using the compositions for inducing humoral and cellular immune responses |
| EP2788477A2 (de) | 2011-12-07 | 2014-10-15 | Institut Pasteur | Identifizierung des porcinen parecho-like virus und anwendungen |
| CN110339160A (zh) | 2012-02-07 | 2019-10-18 | 传染性疾病研究院 | 包含tlr4激动剂的改进佐剂制剂及其使用方法 |
| PT2850431T (pt) | 2012-05-16 | 2018-07-23 | Immune Design Corp | Vacinas para hsv-2 |
| MY168959A (en) | 2012-07-24 | 2019-01-28 | Sanofi Pasteur | Vaccine compositions for the prevention of dengue virus infection |
| CA2878599A1 (en) | 2012-07-24 | 2014-01-30 | Jiansheng Yao | Vaccine compositions for prevention against dengue virus infection |
| BR112015012515B1 (pt) | 2012-11-30 | 2023-04-11 | Sanofi Pasteur | Uso de antígenos, construções de ácido nucleico ou vetores virais capazes de expressar uma partícula do tipo vírus (vlp) da dengue e de uma vacina contra sarampo, uma vacina contra caxumba e uma vacina contra rubéola |
| EP3711768A1 (de) | 2013-04-18 | 2020-09-23 | Immune Design Corp. | Gla-monotherapie zur verwendung in der krebsbehandlung |
| US9463198B2 (en) | 2013-06-04 | 2016-10-11 | Infectious Disease Research Institute | Compositions and methods for reducing or preventing metastasis |
| IL310015B2 (en) | 2013-12-31 | 2026-02-01 | Access To Advanced Health Inst | Single vial formulation |
| EA201691452A1 (ru) | 2014-01-21 | 2016-12-30 | Иммьюн Дизайн Корп. | Композиции для применения в лечении аллергических состояний |
| US20150359880A1 (en) * | 2014-06-16 | 2015-12-17 | Biomune Company | Dual adjuvant vaccine compositions, preparation and uses |
| AR102547A1 (es) | 2014-11-07 | 2017-03-08 | Takeda Vaccines Inc | Vacunas contra la enfermedad de manos, pies y boca y métodos de fabricación y su uso |
| AR102548A1 (es) | 2014-11-07 | 2017-03-08 | Takeda Vaccines Inc | Vacunas contra la enfermedad de manos, pies y boca y métodos de fabricación y uso |
| GB201518684D0 (en) | 2015-10-21 | 2015-12-02 | Glaxosmithkline Biolog Sa | Vaccine |
| CN106267184B (zh) * | 2016-03-03 | 2020-01-21 | 彭建彪 | 一种水包油包水型乳化剂及其用途和使用方法 |
| MY204084A (en) | 2017-06-11 | 2024-08-06 | Molecular Express Inc | Methods and compositions for substance use disorder vaccine formulations and uses thereof |
| CA3081586A1 (en) | 2017-11-03 | 2019-05-09 | Takeda Vaccines, Inc. | Zika vaccines and immunogenic compositions, and methods of using the same |
| BR112021023726A2 (pt) | 2019-05-25 | 2022-02-15 | Infectious Disease Res Inst | Composição e método para secagem por pulverização de uma emulsão de vacina adjuvante |
| CN115089702B (zh) * | 2022-07-05 | 2026-02-13 | 天康制药股份有限公司 | W/o/w转相疫苗佐剂、制备方法及应用 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1408437A (fr) * | 1963-10-14 | 1965-08-13 | Lummus Co | Procédé de récupération du potentiel calorique d'un gaz liquéfié pendant la regazéification |
| GB1080994A (en) * | 1963-10-25 | 1967-08-31 | Nat Res Dev | Injectable emulsions containing antigens |
| GB1408437A (en) * | 1972-10-16 | 1975-10-01 | C Vet Ltd | Vaccines |
| US3983228A (en) * | 1973-08-28 | 1976-09-28 | Merck & Co., Inc. | Water-in-oil adjuvant composition |
| US4069313A (en) * | 1974-11-19 | 1978-01-17 | Merck & Co., Inc. | Water-in-oil adjuvant composition |
| JPS60199833A (ja) * | 1984-03-26 | 1985-10-09 | Meiji Milk Prod Co Ltd | 医薬品、化粧品等用w/o/w型複合エマルジヨンの製造法 |
| IL74289A (en) * | 1985-02-10 | 1989-02-28 | Israel State | Vaccine system comprising a live-non-virulent vaccine and an adjuvant |
| US4803070A (en) * | 1986-04-15 | 1989-02-07 | Ribi Immunochem Research Inc. | Immunological emulsion adjuvants for polysaccharide vaccines |
| AU614465B2 (en) * | 1989-04-05 | 1991-08-29 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Medicinal emulsions |
| JPH07501259A (ja) * | 1990-06-01 | 1995-02-09 | リサーチ コーポレイション テクノロジーズ,インコーポレイテッド | 自己乳化型ガラス |
-
1989
- 1989-07-03 FR FR8908917A patent/FR2649012B1/fr not_active Expired - Fee Related
-
1990
- 1990-06-29 DK DK90910772.4T patent/DK0480981T3/da active
- 1990-06-29 EP EP90910772A patent/EP0480981B1/de not_active Expired - Lifetime
- 1990-06-29 AT AT90910772T patent/ATE96037T1/de not_active IP Right Cessation
- 1990-06-29 DE DE90910772T patent/DE69004094T2/de not_active Expired - Fee Related
- 1990-06-29 JP JP2510000A patent/JP2851422B2/ja not_active Expired - Fee Related
- 1990-06-29 BR BR909007501A patent/BR9007501A/pt not_active Application Discontinuation
- 1990-06-29 US US07/778,843 patent/US5424067A/en not_active Expired - Lifetime
- 1990-06-29 ES ES90910772T patent/ES2061054T3/es not_active Expired - Lifetime
- 1990-06-29 AU AU59610/90A patent/AU643690B2/en not_active Ceased
- 1990-06-29 WO PCT/FR1990/000484 patent/WO1991000106A1/fr not_active Ceased
- 1990-07-03 NZ NZ234336A patent/NZ234336A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO1991000106A1 (fr) | 1991-01-10 |
| DE69004094T2 (de) | 1994-02-17 |
| NZ234336A (en) | 1992-07-28 |
| AU643690B2 (en) | 1993-11-25 |
| DE69004094D1 (de) | 1993-11-25 |
| JPH04507405A (ja) | 1992-12-24 |
| FR2649012B1 (fr) | 1991-10-25 |
| EP0480981A1 (de) | 1992-04-22 |
| DK0480981T3 (da) | 1993-11-29 |
| AU5961090A (en) | 1991-01-17 |
| JP2851422B2 (ja) | 1999-01-27 |
| EP0480981B1 (de) | 1993-10-20 |
| US5424067A (en) | 1995-06-13 |
| ES2061054T3 (es) | 1994-12-01 |
| BR9007501A (pt) | 1992-06-23 |
| FR2649012A1 (fr) | 1991-01-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |