ATE96038T1 - Ein metabolisierbares oel enthaltende impfstoffe und wirkstofftraeger. - Google Patents
Ein metabolisierbares oel enthaltende impfstoffe und wirkstofftraeger.Info
- Publication number
- ATE96038T1 ATE96038T1 AT90910773T AT90910773T ATE96038T1 AT E96038 T1 ATE96038 T1 AT E96038T1 AT 90910773 T AT90910773 T AT 90910773T AT 90910773 T AT90910773 T AT 90910773T AT E96038 T1 ATE96038 T1 AT E96038T1
- Authority
- AT
- Austria
- Prior art keywords
- pct
- sec
- vaccines
- date
- emulsion
- Prior art date
Links
- 229960005486 vaccine Drugs 0.000 title abstract 2
- 239000000839 emulsion Substances 0.000 abstract 2
- 239000003921 oil Substances 0.000 abstract 2
- 239000002671 adjuvant Substances 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 239000003995 emulsifying agent Substances 0.000 abstract 1
- 238000002347 injection Methods 0.000 abstract 1
- 239000007924 injection Substances 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dermatology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Fats And Perfumes (AREA)
- Semiconductor Integrated Circuits (AREA)
- Metal-Oxide And Bipolar Metal-Oxide Semiconductor Integrated Circuits (AREA)
- Design And Manufacture Of Integrated Circuits (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8908918A FR2649013B1 (fr) | 1989-07-03 | 1989-07-03 | Vaccins et vecteurs de principes actifs fluides contenant une huile metabolisable |
| EP90910773A EP0480982B2 (de) | 1989-07-03 | 1990-06-29 | Ein metabolisierbares öl enthaltende impfstoffe und wirkstoffträger |
| PCT/FR1990/000485 WO1991000107A1 (fr) | 1989-07-03 | 1990-06-29 | Vaccins et vecteurs de principes actifs fluides contenant une huile metabolisable |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE96038T1 true ATE96038T1 (de) | 1993-11-15 |
Family
ID=9383410
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT90910773T ATE96038T1 (de) | 1989-07-03 | 1990-06-29 | Ein metabolisierbares oel enthaltende impfstoffe und wirkstofftraeger. |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US5422109A (de) |
| EP (1) | EP0480982B2 (de) |
| JP (1) | JP3007142B2 (de) |
| AT (1) | ATE96038T1 (de) |
| AU (1) | AU655155B2 (de) |
| BR (1) | BR9007502A (de) |
| DE (1) | DE69004095T3 (de) |
| DK (1) | DK0480982T3 (de) |
| ES (1) | ES2061055T5 (de) |
| FR (1) | FR2649013B1 (de) |
| NZ (1) | NZ234337A (de) |
| WO (1) | WO1991000107A1 (de) |
Families Citing this family (67)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2083553A1 (en) * | 1991-11-25 | 1993-05-26 | Kuniharu Seki | Immunogen composition |
| JP3723231B2 (ja) * | 1991-12-23 | 2005-12-07 | ディミナコ アクチェンゲゼルシャフト | アジュバント |
| AU679902B2 (en) * | 1992-09-30 | 1997-07-17 | Ohio State University Research Foundation, The | Vaccines and antigenic conjugates |
| FR2700957B1 (fr) * | 1993-01-29 | 1995-03-03 | Seppic Sa | Composition de vaccin sous-unitaire recombinant vivant et procédé de préparation. |
| FR2702373B1 (fr) * | 1993-03-08 | 1996-06-07 | Rhone Merieux | Emulsions vaccinales fluides eau-dans-l'huile contenant une huile métabolisable. |
| FR2702374B1 (fr) * | 1993-03-08 | 1995-04-14 | Rhone Merieux | Emulsions vaccinales fluides eau-dans-l'huile contenant une huile métabolisable. |
| US6117432A (en) * | 1995-04-20 | 2000-09-12 | Societe D'exploitation De Produits Pour Les Industries Chimiques (S.E.P.P.I.C.) | Therapeutic composition comprising an antigen or an in vivo generator of a compound comprising an amino acid sequence |
| US6689370B1 (en) | 1995-04-20 | 2004-02-10 | Societe D'exploitation De Produits Pour Les Industries Chimiques (S.E.P.P.I.C.) | Therapeutic composition comprising an antigen or an in vivo generator of a compound comprising an amino acid sequence |
| FR2733151B1 (fr) * | 1995-04-20 | 1997-05-23 | Seppic Sa | Composition therapeutique comprenant un antigene ou un generateur in vivo d'un compose comprenant une sequence d'acides amines |
| US5690942A (en) † | 1995-06-02 | 1997-11-25 | American Home Products Corporation | Adjuvants for viral vaccines |
| ATE353225T1 (de) | 1995-11-30 | 2007-02-15 | Chemo Sero Therapeut Res Inst | Öladjuvierter impfstoff und verfahren zu seiner herstellung |
| GB9626865D0 (en) * | 1996-12-24 | 1997-02-12 | Cyanamid Websters Pty Limited | Veterinary vaccines |
| UA78180C2 (uk) | 1997-10-03 | 2007-03-15 | Меріаль | Кільцевий вірус свині типу ii, вакцини та діагностичні реагенти |
| US6524592B2 (en) * | 1997-10-17 | 2003-02-25 | American Home Products Corporation | Veterinary vaccines |
| NZ508013A (en) * | 1998-05-07 | 2003-08-29 | Corixa Corp | Adjuvant composition for use with an antigen in a vaccine composition |
| FR2800280B1 (fr) | 1999-10-29 | 2003-09-19 | Seppic Sa | Nouvelle composition vaccinale et utilisation d'agents tensioactifs comme adjuvants d'immunite |
| JP2001131087A (ja) * | 1999-11-05 | 2001-05-15 | Chemo Sero Therapeut Res Inst | オイルアジュバントワクチン |
| WO2001045670A2 (en) * | 1999-12-23 | 2001-06-28 | Aphton Corporation | A stable immunogenic composition for frozen storage |
| FR2809961B1 (fr) * | 2000-06-09 | 2004-12-03 | Seppic Sa | Utilisation d'ethers de sucres, comme adjuvants d'immunite dans les compositions vaccinales, compositions therapeutiques les renfermant et leur utilisation comme vaccins |
| SI2266603T1 (sl) | 2000-10-18 | 2012-12-31 | Glaxosmithkline Biologicals S.A. | Tumorska cepiva |
| DE60117164T2 (de) * | 2000-11-07 | 2006-08-03 | Immuno Vaccine Technologies Inc., Halifax | Impfstoffe mit erhöhter immunantwort und verfahren zur deren herstellung |
| DE10113284A1 (de) * | 2001-03-16 | 2002-10-02 | Heinrich Exner | Adjuvans-Emulsion und Verfahren zu deren Verwendung |
| FR2823119B1 (fr) * | 2001-04-05 | 2004-02-20 | Seppic Sa | Adjuvant d'immunite contenant un cation metallique complexe et vaccin le contenant |
| FR2824279B1 (fr) * | 2001-05-04 | 2004-05-28 | Seppic Sa | Emulsion e/h concentree |
| GB0409940D0 (en) * | 2004-05-04 | 2004-06-09 | Glaxosmithkline Biolog Sa | Vaccine |
| CA2523032A1 (en) | 2005-10-07 | 2007-04-07 | Immunovaccine Technologies Inc. | Vaccines for cancer therapy |
| GB0607088D0 (en) | 2006-04-07 | 2006-05-17 | Glaxosmithkline Biolog Sa | Vaccine |
| KR101515078B1 (ko) | 2005-12-22 | 2015-04-24 | 글락소스미스클라인 바이오로지칼즈 에스.에이. | 백신 |
| EP2476433A1 (de) | 2006-03-30 | 2012-07-18 | GlaxoSmithKline Biologicals S.A. | Immunogene Zusammensetzung |
| PL2068918T5 (pl) | 2006-09-26 | 2024-12-02 | Access To Advanced Health Institute | Kompozycja szczepionki zawierająca syntetyczny adiuwant |
| US20090181078A1 (en) | 2006-09-26 | 2009-07-16 | Infectious Disease Research Institute | Vaccine composition containing synthetic adjuvant |
| CA2690708A1 (en) | 2007-06-26 | 2008-12-31 | Glaxosmithkline Biologicals S.A. | Vaccine |
| CN106310293A (zh) | 2007-09-27 | 2017-01-11 | 免疫疫苗技术有限公司 | 在包括连续疏水相的载体中的脂质体在体内输送多核苷酸中的应用 |
| US20100209452A1 (en) * | 2007-10-03 | 2010-08-19 | Immunovaccine Technologies, Inc | Compositions comprising an antigen, an amphipathic compound and a hydrophobic carrier, and uses thereof |
| FR2922767B1 (fr) | 2007-10-24 | 2009-12-18 | Seppic Sa | Procede de preparation d'une composition vaccinale comprenant au moins un antigene et au moins un adjuvant. |
| WO2009146523A1 (en) * | 2008-06-05 | 2009-12-10 | Immunovaccine Technologies Inc. | Compositions comprising liposomes, an antigen, a polynucleotide and a carrier comprising a continuous phase of a hydrophobic substance |
| CA2764374C (en) | 2009-06-05 | 2019-11-19 | Infectious Disease Research Institute | Synthetic glucopyranosyl lipid adjuvants |
| GB0913680D0 (en) | 2009-08-05 | 2009-09-16 | Glaxosmithkline Biolog Sa | Immunogenic composition |
| GB0913681D0 (en) | 2009-08-05 | 2009-09-16 | Glaxosmithkline Biolog Sa | Immunogenic composition |
| EP2353609A1 (de) | 2010-02-04 | 2011-08-10 | Sanofi Pasteur | Immunisierungszusammensetzungen und -verfahren |
| FR2956403B1 (fr) | 2010-02-17 | 2014-10-17 | Afssa | Antigenes polypeptidiques de trichinella, et leurs applications |
| GB201003920D0 (en) | 2010-03-09 | 2010-04-21 | Glaxosmithkline Biolog Sa | Method of treatment |
| EA027236B1 (ru) | 2011-04-08 | 2017-07-31 | Иммьюн Дизайн Корп. | Иммуногенные композиции и способы применения таких композиций для индукции гуморального и клеточного иммунного ответа |
| CN113876945A (zh) | 2011-10-06 | 2022-01-04 | 免疫疫苗技术有限公司 | 包括激活或增加tlr2活性的佐剂的脂质体组合物及其应用 |
| WO2013083753A2 (en) | 2011-12-07 | 2013-06-13 | Institut Pasteur | Identification of a swine parecho-like virus and applications |
| ES2729967T3 (es) | 2012-02-07 | 2019-11-07 | Infectious Disease Res Inst | Formulaciones de adyuvante mejoradas que comprenden agonistas de TLR4 y métodos para usar las mismas |
| HRP20181102T1 (hr) | 2012-05-16 | 2018-09-07 | Immune Design Corp | Cjepiva za hsv-2 |
| SG10201912291YA (en) | 2012-07-24 | 2020-02-27 | Sanofi Pasteur | Vaccine compositions |
| AU2013295016A1 (en) | 2012-07-24 | 2015-01-29 | Sanofi Pasteur | Vaccine compositions for prevention against dengue virus infection |
| BR112015012515B1 (pt) | 2012-11-30 | 2023-04-11 | Sanofi Pasteur | Uso de antígenos, construções de ácido nucleico ou vetores virais capazes de expressar uma partícula do tipo vírus (vlp) da dengue e de uma vacina contra sarampo, uma vacina contra caxumba e uma vacina contra rubéola |
| MX370573B (es) | 2013-04-18 | 2019-12-17 | Immune Design Corp | Monoterapia con glucopiranosil lipido a para usarse en el tratamiento del cancer. |
| US9463198B2 (en) | 2013-06-04 | 2016-10-11 | Infectious Disease Research Institute | Compositions and methods for reducing or preventing metastasis |
| EP2821082A1 (de) | 2013-07-05 | 2015-01-07 | Laboratoire Biodim | Verfahren zur Herstellung eines inaktivierten Lentivirus, insbesondere HIV, Impfstoff, Kit und Verfahren zur Verwendung |
| FR3011850B1 (fr) | 2013-10-15 | 2018-04-06 | Cfl Biotech | Vaccin therapeutique contre le cancer a base de proteines de stress rendues immunogenes |
| US10357554B2 (en) | 2013-11-11 | 2019-07-23 | The United States Of America, As Represented By The Secretary Of The Army | AMA-1 epitopes, antibodies, compositions, and methods of making and using the same |
| WO2015077442A2 (en) | 2013-11-20 | 2015-05-28 | La Jolla Institute For Allergy And Immunology | Grass pollen immunogens and methods and uses for immune response modulation |
| AU2014352986A1 (en) | 2013-11-20 | 2016-06-16 | Alk-Abello A/S | Pan pollen immunogens and methods and uses thereof for immune response modulation |
| IL310015B2 (en) | 2013-12-31 | 2026-02-01 | Access To Advanced Health Inst | Single vial formulation |
| WO2015112485A1 (en) | 2014-01-21 | 2015-07-30 | Immune Design Corp. | Compositions for use in the treatment of allergic conditions |
| WO2015131053A1 (en) | 2014-02-28 | 2015-09-03 | Alk-Abelló A/S | Polypeptides derived from phl p and methods and uses thereof for immune response modulation |
| AR102547A1 (es) | 2014-11-07 | 2017-03-08 | Takeda Vaccines Inc | Vacunas contra la enfermedad de manos, pies y boca y métodos de fabricación y su uso |
| AU2015252119A1 (en) | 2014-11-07 | 2016-05-26 | Takeda Vaccines, Inc. | Hand, foot, and mouth vaccines and methods of manufacture and use thereof |
| GB201506948D0 (en) * | 2015-04-23 | 2015-06-10 | Croda Int Plc | Emulsions for injectable formulations |
| GB201518684D0 (en) | 2015-10-21 | 2015-12-02 | Glaxosmithkline Biolog Sa | Vaccine |
| AU2018283973B2 (en) | 2017-06-11 | 2025-04-24 | Molecular Express, Inc. | Methods and compositions for substance use disorder vaccine formulations and uses thereof |
| KR20200117981A (ko) | 2017-11-03 | 2020-10-14 | 다케다 백신즈 인코포레이티드 | 지카 백신 및 면역원성 조성물, 그리고 이를 이용하는 방법들 |
| CA3141577A1 (en) | 2019-05-25 | 2020-12-03 | Infectious Disease Research Institute | Composition and method for spray drying an adjuvant vaccine emulsion |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3678149A (en) * | 1970-01-26 | 1972-07-18 | Samuel J Prigal | Method of enhancing the action of a medicament |
| US3983228A (en) * | 1973-08-28 | 1976-09-28 | Merck & Co., Inc. | Water-in-oil adjuvant composition |
| US4069313A (en) * | 1974-11-19 | 1978-01-17 | Merck & Co., Inc. | Water-in-oil adjuvant composition |
| FR2342073A1 (fr) * | 1976-02-27 | 1977-09-23 | Merieux Inst | Nouveau vaccin antivariolique sous forme de pate et son dispositif d'application |
| FR2501526A1 (fr) * | 1981-03-13 | 1982-09-17 | Montagne Noire Produits Chimiq | Nouveaux emulsionnants et leur application pour la production de vaccins |
| IL74289A (en) * | 1985-02-10 | 1989-02-28 | Israel State | Vaccine system comprising a live-non-virulent vaccine and an adjuvant |
| US4803070A (en) * | 1986-04-15 | 1989-02-07 | Ribi Immunochem Research Inc. | Immunological emulsion adjuvants for polysaccharide vaccines |
-
1989
- 1989-07-03 FR FR8908918A patent/FR2649013B1/fr not_active Expired - Lifetime
-
1990
- 1990-06-29 US US07/778,854 patent/US5422109A/en not_active Expired - Lifetime
- 1990-06-29 BR BR909007502A patent/BR9007502A/pt not_active Application Discontinuation
- 1990-06-29 DE DE69004095T patent/DE69004095T3/de not_active Expired - Fee Related
- 1990-06-29 AT AT90910773T patent/ATE96038T1/de not_active IP Right Cessation
- 1990-06-29 EP EP90910773A patent/EP0480982B2/de not_active Expired - Lifetime
- 1990-06-29 WO PCT/FR1990/000485 patent/WO1991000107A1/fr not_active Ceased
- 1990-06-29 ES ES90910773T patent/ES2061055T5/es not_active Expired - Lifetime
- 1990-06-29 JP JP2510001A patent/JP3007142B2/ja not_active Expired - Fee Related
- 1990-06-29 AU AU59630/90A patent/AU655155B2/en not_active Ceased
- 1990-06-29 DK DK90910773.2T patent/DK0480982T3/da active
- 1990-07-03 NZ NZ234337A patent/NZ234337A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE69004095T2 (de) | 1994-02-17 |
| EP0480982B1 (de) | 1993-10-20 |
| US5422109A (en) | 1995-06-06 |
| FR2649013B1 (fr) | 1991-10-25 |
| DE69004095T3 (de) | 1998-03-05 |
| FR2649013A1 (fr) | 1991-01-04 |
| DE69004095D1 (de) | 1993-11-25 |
| EP0480982A1 (de) | 1992-04-22 |
| ES2061055T3 (es) | 1994-12-01 |
| DK0480982T3 (da) | 1994-03-14 |
| AU5963090A (en) | 1991-01-17 |
| NZ234337A (en) | 1992-12-23 |
| JP3007142B2 (ja) | 2000-02-07 |
| JPH04506521A (ja) | 1992-11-12 |
| AU655155B2 (en) | 1994-12-08 |
| BR9007502A (pt) | 1992-06-23 |
| ES2061055T5 (es) | 1998-03-01 |
| EP0480982B2 (de) | 1997-11-12 |
| WO1991000107A1 (fr) | 1991-01-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |