ATE96228T1 - Vorrichtung fuer chemische testverfahren. - Google Patents

Vorrichtung fuer chemische testverfahren.

Info

Publication number
ATE96228T1
ATE96228T1 AT90908261T AT90908261T ATE96228T1 AT E96228 T1 ATE96228 T1 AT E96228T1 AT 90908261 T AT90908261 T AT 90908261T AT 90908261 T AT90908261 T AT 90908261T AT E96228 T1 ATE96228 T1 AT E96228T1
Authority
AT
Austria
Prior art keywords
pct
cavity
sec
carries
date
Prior art date
Application number
AT90908261T
Other languages
English (en)
Inventor
John Attridge
Alan Martin Smith
Original Assignee
Ars Holding 89 Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ars Holding 89 Nv filed Critical Ars Holding 89 Nv
Application granted granted Critical
Publication of ATE96228T1 publication Critical patent/ATE96228T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/7703—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/648—Specially adapted constructive features of fluorimeters using evanescent coupling or surface plasmon coupling for the excitation of fluorescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0822—Slides
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/16—Surface properties and coatings
    • B01L2300/168—Specific optical properties, e.g. reflective coatings
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0406—Moving fluids with specific forces or mechanical means specific forces capillary forces
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G01N2021/0346—Capillary cells; Microcells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/7703—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides
    • G01N2021/7706—Reagent provision
    • G01N2021/7733—Reservoir, liquid reagent
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N2021/7769—Measurement method of reaction-produced change in sensor
    • G01N2021/7786—Fluorescence

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Optics & Photonics (AREA)
  • Plasma & Fusion (AREA)
  • Medicinal Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AT90908261T 1989-05-18 1990-05-17 Vorrichtung fuer chemische testverfahren. ATE96228T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB898911462A GB8911462D0 (en) 1989-05-18 1989-05-18 Devices for use in chemical test procedures
EP90908261A EP0426817B1 (de) 1989-05-18 1990-05-17 Vorrichtung für chemische testverfahren
PCT/GB1990/000764 WO1990014590A1 (en) 1989-05-18 1990-05-17 Devices for use in chemical test procedures

Publications (1)

Publication Number Publication Date
ATE96228T1 true ATE96228T1 (de) 1993-11-15

Family

ID=10656979

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90908261T ATE96228T1 (de) 1989-05-18 1990-05-17 Vorrichtung fuer chemische testverfahren.

Country Status (11)

Country Link
US (1) US5192502A (de)
EP (1) EP0426817B1 (de)
JP (1) JP2525958B2 (de)
AT (1) ATE96228T1 (de)
AU (1) AU617254B2 (de)
CA (1) CA2031515C (de)
DE (1) DE69004049T2 (de)
DK (1) DK0426817T3 (de)
ES (1) ES2045921T3 (de)
GB (1) GB8911462D0 (de)
WO (1) WO1990014590A1 (de)

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GB9212302D0 (en) * 1992-06-10 1992-07-22 Applied Research Systems Method for improving measurement precision in evanescent wave optical biosensor assays
US5512492A (en) 1993-05-18 1996-04-30 University Of Utah Research Foundation Waveguide immunosensor with coating chemistry providing enhanced sensitivity
AU749504B2 (en) * 1993-05-18 2002-06-27 University Of Utah Research Foundation Apparatus and methods for multianalyte homogeneous fluoroimmunoassays
US5677196A (en) * 1993-05-18 1997-10-14 University Of Utah Research Foundation Apparatus and methods for multi-analyte homogeneous fluoro-immunoassays
WO1994027137A2 (en) * 1993-05-18 1994-11-24 University Of Utah Research Foundation Apparatus and methods for multianalyte homogeneous fluoroimmunoassays
US5919712A (en) 1993-05-18 1999-07-06 University Of Utah Research Foundation Apparatus and methods for multi-analyte homogeneous fluoro-immunoassays
JP3326708B2 (ja) * 1993-08-31 2002-09-24 日水製薬株式会社 光学的測定装置およびその方法
GB9325718D0 (en) * 1993-12-16 1994-02-16 Ars Holding 89 Nv Sensor device for sandwich assay
GB9404749D0 (en) * 1994-03-10 1994-04-27 Ars Holding 89 Nv Device for use in spectrophotometry
US5490972A (en) * 1994-04-29 1996-02-13 Johnson & Johnson Clinical Diagnostics, Inc. Raising mechanism for incubator cover
US5515170A (en) * 1994-09-08 1996-05-07 Lifescan, Inc. Analyte detection device having a serpentine passageway for indicator strips
US5563031A (en) * 1994-09-08 1996-10-08 Lifescan, Inc. Highly stable oxidative coupling dye for spectrophotometric determination of analytes
US5526120A (en) * 1994-09-08 1996-06-11 Lifescan, Inc. Test strip with an asymmetrical end insuring correct insertion for measuring
US6335203B1 (en) * 1994-09-08 2002-01-01 Lifescan, Inc. Optically readable strip for analyte detection having on-strip orientation index
ES2168389T3 (es) * 1994-09-08 2002-06-16 Lifescan Inc Tira de lectura optica y patron incorporado para la deteccion de un analito.
GB9419001D0 (en) 1994-09-21 1994-11-09 Applied Research Systems Assay method
US5599668A (en) * 1994-09-22 1997-02-04 Abbott Laboratories Light scattering optical waveguide method for detecting specific binding events
US5814565A (en) * 1995-02-23 1998-09-29 University Of Utah Research Foundation Integrated optic waveguide immunosensor
US5909227A (en) * 1995-04-12 1999-06-01 Eastman Kodak Company Photograph processing and copying system using coincident force drop-on-demand ink jet printing
EP1291441A3 (de) * 1995-09-12 2003-03-19 Becton, Dickinson and Company Verfahren und Vorrichtung zur DNS-Amplifikation und -Testung
US6794127B1 (en) 1997-06-16 2004-09-21 Diversa Corporation Capillary array-based sample screening
US6972183B1 (en) 1997-06-16 2005-12-06 Diversa Corporation Capillary array-based enzyme screening
GB9609653D0 (en) * 1996-05-09 1996-07-10 Applied Research Ars Holding N Method of assay
AU5895898A (en) * 1996-12-20 1998-07-17 Gamera Bioscience Corporation An affinity binding-based system for detecting particulates in a fluid
US6511854B1 (en) * 1997-07-31 2003-01-28 The Uab Research Foundation Regenerable biosensor using total internal reflection fluorescence with electrochemical control
US6222619B1 (en) 1997-09-18 2001-04-24 University Of Utah Research Foundation Diagnostic device and method
DE19753847A1 (de) * 1997-12-04 1999-06-10 Roche Diagnostics Gmbh Analytisches Testelement mit Kapillarkanal
DE19753851A1 (de) * 1997-12-04 1999-06-10 Roche Diagnostics Gmbh Vorrichtung zum kapillaren Flüssigkeitstransport
DE19753850A1 (de) * 1997-12-04 1999-06-10 Roche Diagnostics Gmbh Probennahmevorrichtung
US6438279B1 (en) 1999-01-07 2002-08-20 Cornell Research Foundation, Inc. Unitary microcapiliary and waveguide structure and method of fabrication
US6771376B2 (en) 1999-07-05 2004-08-03 Novartis Ag Sensor platform, apparatus incorporating the platform, and process using the platform
JP4684507B2 (ja) 1999-07-05 2011-05-18 ノバルティス アーゲー センサープラットホームを使用する方法
US6395483B1 (en) 1999-09-02 2002-05-28 3M Innovative Properties Company Arrays with mask layers
US7167615B1 (en) 1999-11-05 2007-01-23 Board Of Regents, The University Of Texas System Resonant waveguide-grating filters and sensors and methods for making and using same
US6492133B1 (en) 2000-05-01 2002-12-10 3M Innovative Properties Company Reflective disc assay devices, systems and methods
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US8994946B2 (en) 2010-02-19 2015-03-31 Pacific Biosciences Of California, Inc. Integrated analytical system and method
US9372308B1 (en) 2012-06-17 2016-06-21 Pacific Biosciences Of California, Inc. Arrays of integrated analytical devices and methods for production
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US10717671B2 (en) 2015-07-07 2020-07-21 Agc Glass Europe Glass substrate with increased weathering and chemical resistance
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US4978503A (en) * 1984-06-13 1990-12-18 Ares-Serono Research & Development Limited Partnership Devices for use in chemical test procedures
US4824789B1 (en) * 1986-10-10 1996-08-13 Minnesota Mining & Mfg Gas sensor

Also Published As

Publication number Publication date
CA2031515C (en) 1996-06-04
DE69004049T2 (de) 1994-04-07
DE69004049D1 (de) 1993-11-25
AU5740390A (en) 1990-12-18
AU617254B2 (en) 1991-11-21
GB8911462D0 (en) 1989-07-05
ES2045921T3 (es) 1994-01-16
CA2031515A1 (en) 1990-11-19
US5192502A (en) 1993-03-09
EP0426817A1 (de) 1991-05-15
JPH03506078A (ja) 1991-12-26
WO1990014590A1 (en) 1990-11-29
DK0426817T3 (da) 1994-02-21
JP2525958B2 (ja) 1996-08-21
EP0426817B1 (de) 1993-10-20

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