DK0426817T3 - Indretninger til anvendelse ved kemiske testprocedurer - Google Patents

Indretninger til anvendelse ved kemiske testprocedurer

Info

Publication number
DK0426817T3
DK0426817T3 DK90908261.2T DK90908261T DK0426817T3 DK 0426817 T3 DK0426817 T3 DK 0426817T3 DK 90908261 T DK90908261 T DK 90908261T DK 0426817 T3 DK0426817 T3 DK 0426817T3
Authority
DK
Denmark
Prior art keywords
pct
cavity
sec
carries
devices
Prior art date
Application number
DK90908261.2T
Other languages
English (en)
Inventor
John Worthington Attridge
Alan Martin Smith
Original Assignee
Applied Research Systems
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Applied Research Systems filed Critical Applied Research Systems
Application granted granted Critical
Publication of DK0426817T3 publication Critical patent/DK0426817T3/da

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/7703—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/648—Specially adapted constructive features of fluorimeters using evanescent coupling or surface plasmon coupling for the excitation of fluorescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0822—Slides
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/16—Surface properties and coatings
    • B01L2300/168—Specific optical properties, e.g. reflective coatings
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0406—Moving fluids with specific forces or mechanical means specific forces capillary forces
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G01N2021/0346—Capillary cells; Microcells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/7703—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides
    • G01N2021/7706—Reagent provision
    • G01N2021/7733—Reservoir, liquid reagent
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N2021/7769—Measurement method of reaction-produced change in sensor
    • G01N2021/7786—Fluorescence

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Optics & Photonics (AREA)
  • Medicinal Chemistry (AREA)
  • Plasma & Fusion (AREA)
  • Dispersion Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DK90908261.2T 1989-05-18 1990-05-17 Indretninger til anvendelse ved kemiske testprocedurer DK0426817T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB898911462A GB8911462D0 (en) 1989-05-18 1989-05-18 Devices for use in chemical test procedures

Publications (1)

Publication Number Publication Date
DK0426817T3 true DK0426817T3 (da) 1994-02-21

Family

ID=10656979

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90908261.2T DK0426817T3 (da) 1989-05-18 1990-05-17 Indretninger til anvendelse ved kemiske testprocedurer

Country Status (11)

Country Link
US (1) US5192502A (da)
EP (1) EP0426817B1 (da)
JP (1) JP2525958B2 (da)
AT (1) ATE96228T1 (da)
AU (1) AU617254B2 (da)
CA (1) CA2031515C (da)
DE (1) DE69004049T2 (da)
DK (1) DK0426817T3 (da)
ES (1) ES2045921T3 (da)
GB (1) GB8911462D0 (da)
WO (1) WO1990014590A1 (da)

Families Citing this family (64)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9008261D0 (en) * 1990-04-11 1990-06-13 Ares Serono Res & Dev Ltd Method of improving assay sensitivity
GB9212302D0 (en) * 1992-06-10 1992-07-22 Applied Research Systems Method for improving measurement precision in evanescent wave optical biosensor assays
GB9212305D0 (en) * 1992-06-10 1992-07-22 Applied Research Systems Sensor for optical assay
WO1994027137A2 (en) * 1993-05-18 1994-11-24 University Of Utah Research Foundation Apparatus and methods for multianalyte homogeneous fluoroimmunoassays
US5512492A (en) * 1993-05-18 1996-04-30 University Of Utah Research Foundation Waveguide immunosensor with coating chemistry providing enhanced sensitivity
AU749504B2 (en) * 1993-05-18 2002-06-27 University Of Utah Research Foundation Apparatus and methods for multianalyte homogeneous fluoroimmunoassays
US5919712A (en) 1993-05-18 1999-07-06 University Of Utah Research Foundation Apparatus and methods for multi-analyte homogeneous fluoro-immunoassays
US5677196A (en) * 1993-05-18 1997-10-14 University Of Utah Research Foundation Apparatus and methods for multi-analyte homogeneous fluoro-immunoassays
JP3326708B2 (ja) * 1993-08-31 2002-09-24 日水製薬株式会社 光学的測定装置およびその方法
GB9325718D0 (en) * 1993-12-16 1994-02-16 Ars Holding 89 Nv Sensor device for sandwich assay
GB9404749D0 (en) * 1994-03-10 1994-04-27 Ars Holding 89 Nv Device for use in spectrophotometry
US5490972A (en) * 1994-04-29 1996-02-13 Johnson & Johnson Clinical Diagnostics, Inc. Raising mechanism for incubator cover
JP3488925B2 (ja) * 1994-09-08 2004-01-19 ライフスキヤン・インコーポレーテツド 条片上標準を備えた分析物検出用の光学読取式条片
US5515170A (en) * 1994-09-08 1996-05-07 Lifescan, Inc. Analyte detection device having a serpentine passageway for indicator strips
US5563031A (en) * 1994-09-08 1996-10-08 Lifescan, Inc. Highly stable oxidative coupling dye for spectrophotometric determination of analytes
US6335203B1 (en) * 1994-09-08 2002-01-01 Lifescan, Inc. Optically readable strip for analyte detection having on-strip orientation index
US5526120A (en) * 1994-09-08 1996-06-11 Lifescan, Inc. Test strip with an asymmetrical end insuring correct insertion for measuring
GB9419001D0 (en) 1994-09-21 1994-11-09 Applied Research Systems Assay method
US5599668A (en) * 1994-09-22 1997-02-04 Abbott Laboratories Light scattering optical waveguide method for detecting specific binding events
US5814565A (en) * 1995-02-23 1998-09-29 University Of Utah Research Foundation Integrated optic waveguide immunosensor
US5909227A (en) * 1995-04-12 1999-06-01 Eastman Kodak Company Photograph processing and copying system using coincident force drop-on-demand ink jet printing
US6143247A (en) * 1996-12-20 2000-11-07 Gamera Bioscience Inc. Affinity binding-based system for detecting particulates in a fluid
EP1291441A3 (en) * 1995-09-12 2003-03-19 Becton, Dickinson and Company Device and method for DNA amplification and assay
US6794127B1 (en) 1997-06-16 2004-09-21 Diversa Corporation Capillary array-based sample screening
US6972183B1 (en) 1997-06-16 2005-12-06 Diversa Corporation Capillary array-based enzyme screening
GB9609653D0 (en) * 1996-05-09 1996-07-10 Applied Research Ars Holding N Method of assay
US6511854B1 (en) * 1997-07-31 2003-01-28 The Uab Research Foundation Regenerable biosensor using total internal reflection fluorescence with electrochemical control
US6222619B1 (en) 1997-09-18 2001-04-24 University Of Utah Research Foundation Diagnostic device and method
DE19753847A1 (de) 1997-12-04 1999-06-10 Roche Diagnostics Gmbh Analytisches Testelement mit Kapillarkanal
DE19753851A1 (de) * 1997-12-04 1999-06-10 Roche Diagnostics Gmbh Vorrichtung zum kapillaren Flüssigkeitstransport
DE19753850A1 (de) 1997-12-04 1999-06-10 Roche Diagnostics Gmbh Probennahmevorrichtung
US6438279B1 (en) 1999-01-07 2002-08-20 Cornell Research Foundation, Inc. Unitary microcapiliary and waveguide structure and method of fabrication
KR100883079B1 (ko) 1999-07-05 2009-02-10 노파르티스 아게 플랫폼, 플랫폼을 가지는 장치, 및 플랫폼을 사용하는 방법
US6771376B2 (en) * 1999-07-05 2004-08-03 Novartis Ag Sensor platform, apparatus incorporating the platform, and process using the platform
US6395483B1 (en) 1999-09-02 2002-05-28 3M Innovative Properties Company Arrays with mask layers
US7167615B1 (en) 1999-11-05 2007-01-23 Board Of Regents, The University Of Texas System Resonant waveguide-grating filters and sensors and methods for making and using same
US6492133B1 (en) * 2000-05-01 2002-12-10 3M Innovative Properties Company Reflective disc assay devices, systems and methods
JP2002202305A (ja) * 2000-12-28 2002-07-19 Ebara Corp アフィニテイー検出分析チップ、その作製方法、それを用いる検出方法及び検出システム
US7310543B2 (en) * 2001-03-26 2007-12-18 Kumetrix, Inc. Silicon microprobe with integrated biosensor
DE10134650B4 (de) 2001-07-20 2009-12-03 Roche Diagnostics Gmbh System zur Entnahme kleiner Körperflüssigkeitsmengen
DE10220296A1 (de) * 2002-05-07 2003-11-20 Roche Diagnostics Gmbh Vorrichtung zur Probennahme von flüssigen Proben
US8038337B2 (en) * 2003-02-27 2011-10-18 Beckman Coulter, Inc. Method and device for blending small quantities of liquid in microcavities
EP1596972B1 (de) * 2003-02-27 2008-01-09 Advalytix AG Verfahren und vorrichtung zur erzeugung von bewegung in einem dünnen flüssigkeitsfilm
DE10325313B3 (de) * 2003-02-27 2004-07-29 Advalytix Ag Verfahren und Vorrichtung zur Erzeugung von Bewegung in einem dünnen Flüssigkeitsfilm
JP3878144B2 (ja) * 2003-03-19 2007-02-07 富士フイルムホールディングス株式会社 生化学解析用ユニット
US8207509B2 (en) 2006-09-01 2012-06-26 Pacific Biosciences Of California, Inc. Substrates, systems and methods for analyzing materials
EP3936857B1 (en) 2006-09-01 2023-06-21 Pacific Biosciences Of California, Inc. Substrates, systems and methods for analyzing materials
CA2737505C (en) 2008-09-16 2017-08-29 Pacific Biosciences Of California, Inc. Substrates and optical systems and methods of use thereof
US8994946B2 (en) 2010-02-19 2015-03-31 Pacific Biosciences Of California, Inc. Integrated analytical system and method
CN102985803A (zh) 2010-02-19 2013-03-20 加利福尼亚太平洋生物科学股份有限公司 集成的分析系统和方法
US9372308B1 (en) 2012-06-17 2016-06-21 Pacific Biosciences Of California, Inc. Arrays of integrated analytical devices and methods for production
US9223084B2 (en) 2012-12-18 2015-12-29 Pacific Biosciences Of California, Inc. Illumination of optical analytical devices
US9624540B2 (en) 2013-02-22 2017-04-18 Pacific Biosciences Of California, Inc. Integrated illumination of optical analytical devices
EP3186617A4 (en) 2014-08-27 2018-04-25 Pacific Biosciences Of California, Inc. Arrays of integrated analytcal devices
EP3271762B1 (en) 2015-03-16 2023-01-04 Pacific Biosciences of California, Inc. Analytical system comprising integrated devices and systems for free-space optical coupling
AU2016259012C1 (en) 2015-05-07 2022-11-17 Pacific Biosciences Of California, Inc. Multiprocessor pipeline architecture
EP4425153A3 (en) 2015-06-12 2024-11-20 Pacific Biosciences Of California, Inc. Integrated target waveguide devices and systems for optical coupling
US9851290B2 (en) * 2015-06-22 2017-12-26 Sharp Laboratories Of America, Inc. Particle detector for particulate matter accumulated on a surface
WO2017005621A1 (en) 2015-07-07 2017-01-12 Agc Glass Europe Glass substrate with increased weathering and chemcial resistance
US11602751B2 (en) * 2017-03-31 2023-03-14 Forward Biotech, Inc. Liquid evaluation
WO2020154248A1 (en) 2019-01-21 2020-07-30 Forward Biotech, Inc. Liquid evaluation
CN115362398A (zh) 2020-02-18 2022-11-18 加利福尼亚太平洋生物科学股份有限公司 高度复用的核酸测序系统
TW202244488A (zh) 2021-05-04 2022-11-16 美商加州太平洋生物科學公司 具有縮尺單位單元之整合式分析裝置之陣列
WO2023107663A1 (en) 2021-12-09 2023-06-15 Forward Biotech, Inc. Liquid evaluation device

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4447546A (en) * 1982-08-23 1984-05-08 Myron J. Block Fluorescent immunoassay employing optical fiber in capillary tube
US4978503A (en) * 1984-06-13 1990-12-18 Ares-Serono Research & Development Limited Partnership Devices for use in chemical test procedures
US4824789B1 (en) * 1986-10-10 1996-08-13 Minnesota Mining & Mfg Gas sensor

Also Published As

Publication number Publication date
GB8911462D0 (en) 1989-07-05
CA2031515C (en) 1996-06-04
EP0426817B1 (en) 1993-10-20
JPH03506078A (ja) 1991-12-26
AU5740390A (en) 1990-12-18
DE69004049D1 (de) 1993-11-25
EP0426817A1 (en) 1991-05-15
ES2045921T3 (es) 1994-01-16
US5192502A (en) 1993-03-09
AU617254B2 (en) 1991-11-21
DE69004049T2 (de) 1994-04-07
ATE96228T1 (de) 1993-11-15
WO1990014590A1 (en) 1990-11-29
JP2525958B2 (ja) 1996-08-21
CA2031515A1 (en) 1990-11-19

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