ATE96795T1 - Heteroarylsubstituierte imidazo(4,5-c>pyridine. - Google Patents

Heteroarylsubstituierte imidazo(4,5-c>pyridine.

Info

Publication number: ATE96795T1
Authority: AT; Austria
Prior art keywords: heteroaryl; pyridine; substituted imidazo; substituted; relates
Prior art date: 1989-09-13

Application number

AT90117520T

Other languages

English (en)

Inventor

Ish K Khanna

Richard Mathias Weier

Original Assignee

Searle & Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-09-13

Filing date

1990-09-11

Publication date

1993-11-15

1990-09-11 Application filed by Searle & Co filed Critical Searle & Co

1993-11-15 Application granted granted Critical

1993-11-15 Publication of ATE96795T1 publication Critical patent/ATE96795T1/de

Links

JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 title 2
UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 title 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
125000004857 imidazopyridinyl group Chemical class N1C(=NC2=C1C=CC=N2)* 0.000 abstract 2
HVAUUPRFYPCOCA-AREMUKBSSA-N 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCCOC[C@@H](OC(C)=O)COP([O-])(=O)OCC[N+](C)(C)C HVAUUPRFYPCOCA-AREMUKBSSA-N 0.000 abstract 1
108010003541 Platelet Activating Factor Proteins 0.000 abstract 1
201000010099 disease Diseases 0.000 abstract 1
208000035475 disorder Diseases 0.000 abstract 1
230000001404 mediated effect Effects 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Pulmonology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)
Electroluminescent Light Sources (AREA)

AT90117520T 1989-09-13 1990-09-11 Heteroarylsubstituierte imidazo(4,5-c>pyridine. ATE96795T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US07/406,674 US4990518A (en)	1989-09-13	1989-09-13	Pharmacologically active heteroaryl substituted imidazo (4,5-c) pyridines
EP90117520A EP0417745B1 (de)	1989-09-13	1990-09-11	Heteroarylsubstituierte Imidazo[4,5-c]pyridine

Publications (1)

Publication Number	Publication Date
ATE96795T1 true ATE96795T1 (de)	1993-11-15

Family

ID=23608994

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT90117520T ATE96795T1 (de)	1989-09-13	1990-09-11	Heteroarylsubstituierte imidazo(4,5-c>pyridine.

Country Status (10)

Country	Link
US (1)	US4990518A (de)
EP (1)	EP0417745B1 (de)
JP (1)	JPH03109386A (de)
AT (1)	ATE96795T1 (de)
CA (1)	CA2025084A1 (de)
DE (1)	DE69004389T2 (de)
DK (1)	DK0417745T3 (de)
ES (1)	ES2059942T3 (de)
IE (1)	IE903314A1 (de)
PT (1)	PT95296A (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5208242A (en) *	1992-08-26	1993-05-04	G. D. Searle & Co.	5-substituted-4-phenyl-5H-imidazo[4,5-c]pyridine derivatives
US5635514A (en) *	1994-10-25	1997-06-03	G. D. Searle & Company	Heteroaralkyl and heteroarylthioalkyl thiophenolic compounds as 5-lipoxgenase inhibitors
WO2002053544A1 (en) *	2000-12-29	2002-07-11	Darwin Discovery Ltd.	Pharmaceutical uses and synthesis of nicotinanilide-n-oxides
GB0215293D0 (en) *	2002-07-03	2002-08-14	Rega Foundation	Viral inhibitors
DK2161273T3 (en) *	2003-12-22	2015-07-20	Leuven K U Res & Dev	Imidazo [4,5-C] pyridine compounds and methods for antiviral therapy
CN101027303A (zh) *	2004-07-27	2007-08-29	吉里德科学公司	咪唑并[4，5－d]嘧啶类、其应用和制备方法
PT1841765E (pt) *	2004-12-21	2009-05-14	Gilead Sciences Inc	Anticorpos para mcp-1 humano
US7754720B2 (en) *	2006-07-07	2010-07-13	Gilead Sciences, Inc.	Pyridazine compound and use thereof
UA99466C2 (en)	2007-07-06	2012-08-27	Гилиад Сайенсиз, Инк.	Crystalline pyridazine compound

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4281005A (en) *	1979-03-05	1981-07-28	Merck & Co., Inc.	Novel 2-pyridylimidazole compounds
DE2927987A1 (de) *	1979-07-11	1981-02-05	Thomae Gmbh Dr K	Neue 2-alkoxyphenyl-imidazo eckige klammer auf 4,5-b eckige klammer zu pyridine, deren herstellung und deren verwendung als arzneimittel
AT382377B (de) *	1985-04-27	1987-02-25	Beecham Group Plc	Verfahren zur herstellung von neuen 7-substituierten aminopyrazolo(4,3-b)pyridinen
US4804658A (en) *	1986-09-15	1989-02-14	G. D. Searle & Co.	Imidazopyridine derivatives and pharmaceutical compositions
MY104933A (en) *	1987-09-30	1994-07-30	Pfizer Ltd	Platelet activating factor antagonists
US5019581A (en) *	1988-03-14	1991-05-28	G. D. Searle & Co.	5-substituted (4,5-c) imidazopyridine compounds which have useful platelet activating factor antagonistic activity
US4914108A (en) *	1988-03-14	1990-04-03	G. D. Searle & Co.	5-substituted(4,5-c)imidazopyridine compounds which have useful platelet activating factor antagonistic activity

1989
- 1989-09-13 US US07/406,674 patent/US4990518A/en not_active Expired - Fee Related
1990
- 1990-09-11 DE DE90117520T patent/DE69004389T2/de not_active Expired - Fee Related
- 1990-09-11 AT AT90117520T patent/ATE96795T1/de active
- 1990-09-11 DK DK90117520.8T patent/DK0417745T3/da active
- 1990-09-11 CA CA002025084A patent/CA2025084A1/en not_active Abandoned
- 1990-09-11 EP EP90117520A patent/EP0417745B1/de not_active Expired - Lifetime
- 1990-09-11 ES ES90117520T patent/ES2059942T3/es not_active Expired - Lifetime
- 1990-09-12 IE IE331490A patent/IE903314A1/en unknown
- 1990-09-12 JP JP2242304A patent/JPH03109386A/ja active Pending
- 1990-09-12 PT PT95296A patent/PT95296A/pt not_active Application Discontinuation

Also Published As

Publication number	Publication date
EP0417745B1 (de)	1993-11-03
IE903314A1 (en)	1991-04-10
JPH03109386A (ja)	1991-05-09
DK0417745T3 (da)	1993-12-13
EP0417745A2 (de)	1991-03-20
ES2059942T3 (es)	1994-11-16
CA2025084A1 (en)	1991-03-14
PT95296A (pt)	1991-05-22
DE69004389T2 (de)	1994-03-24
US4990518A (en)	1991-02-05
DE69004389D1 (de)	1993-12-09
EP0417745A3 (en)	1991-11-06

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