DK0417745T3 - Heteroarylsubstituerede imidazo(4,5-c)pyridiner - Google Patents

Heteroarylsubstituerede imidazo(4,5-c)pyridiner

Info

Publication number: DK0417745T3
Authority: DK; Denmark
Prior art keywords: pyridines; heteroaryl; substituted imidazo; substituted; relates
Prior art date: 1989-09-13

Application number

DK90117520.8T

Other languages

Danish (da)

English (en)

Inventor

Ish K Khanna

Richard Mathias Weier

Original Assignee

Searle & Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-09-13

Filing date

1990-09-11

Publication date

1993-12-13

1990-09-11 Application filed by Searle & Co filed Critical Searle & Co

1993-12-13 Application granted granted Critical

1993-12-13 Publication of DK0417745T3 publication Critical patent/DK0417745T3/da

Links

UBOOKRVGOBKDMM-UHFFFAOYSA-N 3h-imidazo[4,5-c]pyridine Chemical class C1=NC=C2NC=NC2=C1 UBOOKRVGOBKDMM-UHFFFAOYSA-N 0.000 title 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
125000004857 imidazopyridinyl group Chemical class N1C(=NC2=C1C=CC=N2)* 0.000 abstract 2
HVAUUPRFYPCOCA-AREMUKBSSA-N 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCCOC[C@@H](OC(C)=O)COP([O-])(=O)OCC[N+](C)(C)C HVAUUPRFYPCOCA-AREMUKBSSA-N 0.000 abstract 1
108010003541 Platelet Activating Factor Proteins 0.000 abstract 1
201000010099 disease Diseases 0.000 abstract 1
208000035475 disorder Diseases 0.000 abstract 1
230000001404 mediated effect Effects 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Pulmonology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)
Electroluminescent Light Sources (AREA)

DK90117520.8T 1989-09-13 1990-09-11 Heteroarylsubstituerede imidazo(4,5-c)pyridiner DK0417745T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/406,674 US4990518A (en)	1989-09-13	1989-09-13	Pharmacologically active heteroaryl substituted imidazo (4,5-c) pyridines

Publications (1)

Publication Number	Publication Date
DK0417745T3 true DK0417745T3 (da)	1993-12-13

Family

ID=23608994

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK90117520.8T DK0417745T3 (da)	1989-09-13	1990-09-11	Heteroarylsubstituerede imidazo(4,5-c)pyridiner

Country Status (10)

Country	Link
US (1)	US4990518A (de)
EP (1)	EP0417745B1 (de)
JP (1)	JPH03109386A (de)
AT (1)	ATE96795T1 (de)
CA (1)	CA2025084A1 (de)
DE (1)	DE69004389T2 (de)
DK (1)	DK0417745T3 (de)
ES (1)	ES2059942T3 (de)
IE (1)	IE903314A1 (de)
PT (1)	PT95296A (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5208242A (en) *	1992-08-26	1993-05-04	G. D. Searle & Co.	5-substituted-4-phenyl-5H-imidazo[4,5-c]pyridine derivatives
US5635514A (en) *	1994-10-25	1997-06-03	G. D. Searle & Company	Heteroaralkyl and heteroarylthioalkyl thiophenolic compounds as 5-lipoxgenase inhibitors
WO2002053544A1 (en) *	2000-12-29	2002-07-11	Darwin Discovery Ltd.	Pharmaceutical uses and synthesis of nicotinanilide-n-oxides
GB0215293D0 (en)	2002-07-03	2002-08-14	Rega Foundation	Viral inhibitors
ATE544765T1 (de) *	2003-12-22	2012-02-15	Leuven K U Res & Dev	Imidazoä4,5-cüpyridinverbindungen und verfahren zur antiviralen behandlung
BRPI0513811A (pt) *	2004-07-27	2008-07-15	Gilead Sciences Inc	imidazo [4,5-d] pirimidinas, seus usos e processos de preparação
NZ556624A (en) *	2004-12-21	2010-06-25	Gilead Sciences Inc	5-((3-(2,4-trifluoromethyphenyl)isoxazol-5-yl)methyl)-2-(2-fluorophenyl)-5H-imidazo[4,5-c]pyridine and method of antiviral treatment
SG175604A1 (en) *	2006-07-07	2011-11-28	Gilead Sciences Inc	Novel pyridazine compound and use thereof
UA99466C2 (en)	2007-07-06	2012-08-27	Гилиад Сайенсиз, Инк.	Crystalline pyridazine compound

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4281005A (en) *	1979-03-05	1981-07-28	Merck & Co., Inc.	Novel 2-pyridylimidazole compounds
DE2927987A1 (de) *	1979-07-11	1981-02-05	Thomae Gmbh Dr K	Neue 2-alkoxyphenyl-imidazo eckige klammer auf 4,5-b eckige klammer zu pyridine, deren herstellung und deren verwendung als arzneimittel
AT382377B (de) *	1985-04-27	1987-02-25	Beecham Group Plc	Verfahren zur herstellung von neuen 7-substituierten aminopyrazolo(4,3-b)pyridinen
US4804658A (en) *	1986-09-15	1989-02-14	G. D. Searle & Co.	Imidazopyridine derivatives and pharmaceutical compositions
MY104933A (en) *	1987-09-30	1994-07-30	Pfizer Ltd	Platelet activating factor antagonists
US5019581A (en) *	1988-03-14	1991-05-28	G. D. Searle & Co.	5-substituted (4,5-c) imidazopyridine compounds which have useful platelet activating factor antagonistic activity
US4914108A (en) *	1988-03-14	1990-04-03	G. D. Searle & Co.	5-substituted(4,5-c)imidazopyridine compounds which have useful platelet activating factor antagonistic activity

1989
- 1989-09-13 US US07/406,674 patent/US4990518A/en not_active Expired - Fee Related
1990
- 1990-09-11 DK DK90117520.8T patent/DK0417745T3/da active
- 1990-09-11 ES ES90117520T patent/ES2059942T3/es not_active Expired - Lifetime
- 1990-09-11 CA CA002025084A patent/CA2025084A1/en not_active Abandoned
- 1990-09-11 AT AT90117520T patent/ATE96795T1/de active
- 1990-09-11 EP EP90117520A patent/EP0417745B1/de not_active Expired - Lifetime
- 1990-09-11 DE DE90117520T patent/DE69004389T2/de not_active Expired - Fee Related
- 1990-09-12 IE IE331490A patent/IE903314A1/en unknown
- 1990-09-12 PT PT95296A patent/PT95296A/pt not_active Application Discontinuation
- 1990-09-12 JP JP2242304A patent/JPH03109386A/ja active Pending

Also Published As

Publication number	Publication date
CA2025084A1 (en)	1991-03-14
IE903314A1 (en)	1991-04-10
ES2059942T3 (es)	1994-11-16
EP0417745B1 (de)	1993-11-03
EP0417745A3 (en)	1991-11-06
EP0417745A2 (de)	1991-03-20
PT95296A (pt)	1991-05-22
JPH03109386A (ja)	1991-05-09
DE69004389D1 (de)	1993-12-09
DE69004389T2 (de)	1994-03-24
ATE96795T1 (de)	1993-11-15
US4990518A (en)	1991-02-05

Publication	Publication Date	Title
DE3773737D1 (de)	1991-11-21	4,5,6,7-tetrahydro-1h-imidazo(4,5-c)pyridinderivate und analoge mit antihypertensiver wirkung.
PT87745A (pt)	1988-07-01	Process for the preparation of pharmaceutical compounds containing cyclosporins
DK0471236T3 (da)	1995-07-24	Imidazopyridinderivater og deres anvendelse
NO873125D0 (no)	1987-07-27	Fremgangsmaate for fremstilling av antibakterielle forbindelser.
ES2191659T3 (es)	2003-09-16	Derivados heterociclicos substituidos utiles como inhibidores de la agregacion plaquetaria.
ES2086579T3 (es)	1996-07-01	Antagonista de leucotrieno b4.
ATE96795T1 (de)	1993-11-15	Heteroarylsubstituierte imidazo(4,5-c>pyridine.
FI882358A0 (fi)	1988-05-19	Cykliska antikoagulationspeptider.
ZA883444B (de)	1988-11-16
ATE40369T1 (de)	1989-02-15	Purinderivate.
NO905254L (no)	1991-06-07	Fremgangsmaate for fremstilling av substituerte cykloheksener.
ATE201406T1 (de)	2001-06-15	Bizyklische verbindungen als eaa rezeptor antagonisten
ATE169917T1 (de)	1998-09-15	Imidazo (4,5-c)pyridinderivate als paf antagonisten
ATE122044T1 (de)	1995-05-15	Pyrrolo(1,2-a>imidazol- und imidazo(1,2- a>pyridinderivate und ihre anwendung als 5- lipoxygenase inhibitoren.
ATE88176T1 (de)	1993-04-15	2-hydroxy-3-aryloxy-propylaminderivate mit kardiovaskulaerer wirkung.
DK305184A (da)	1984-12-24	Hexahydropyrrolo(2,1-a)isoquinolin-derivater
YU158691A (sh)	1994-06-10	2-(4-PIPERIDINIL)-1H-PIRIDO[4,3-b]INDOL-1-ONI IN SORODNE SPOJINE, INTERMEDIATI IN POSTOPEK ZA NJIHOVO PROPRAVO
ITMI920082A1 (it)	1993-07-17	Derivati solforati di acidi biliari