ATE97001T1 - Topisch anzuwendende defibrotid enthaltende arzneizubereitungen. - Google Patents

Topisch anzuwendende defibrotid enthaltende arzneizubereitungen.

Info

Publication number: ATE97001T1
Authority: AT; Austria
Prior art keywords: topical; defibrotid; containing medications; medications; therapy
Prior art date: 1989-09-07

Application number

AT90202172T

Other languages

English (en)

Inventor

Marisa Mantovani

Giuseppe Prino

Roberto Porta

Original Assignee

Crinos Industria Farmaco

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-09-07

Filing date

1990-08-10

Publication date

1993-11-15

1990-08-10 Application filed by Crinos Industria Farmaco filed Critical Crinos Industria Farmaco

1993-11-15 Application granted granted Critical

1993-11-15 Publication of ATE97001T1 publication Critical patent/ATE97001T1/de

Links

230000000699 topical effect Effects 0.000 title abstract 2
229940079593 drug Drugs 0.000 title 1
239000003814 drug Substances 0.000 title 1
JNWFIPVDEINBAI-UHFFFAOYSA-N [5-hydroxy-4-[4-(1-methylindol-5-yl)-5-oxo-1H-1,2,4-triazol-3-yl]-2-propan-2-ylphenyl] dihydrogen phosphate Chemical compound C1=C(OP(O)(O)=O)C(C(C)C)=CC(C=2N(C(=O)NN=2)C=2C=C3C=CN(C)C3=CC=2)=C1O JNWFIPVDEINBAI-UHFFFAOYSA-N 0.000 abstract 1
239000008280 blood Substances 0.000 abstract 1
210000004369 blood Anatomy 0.000 abstract 1
229960004120 defibrotide Drugs 0.000 abstract 1
230000007170 pathology Effects 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
238000002560 therapeutic procedure Methods 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/755—Polymers containing halogen
- A61K31/76—Polymers containing halogen of vinyl chloride
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Epidemiology (AREA)
Molecular Biology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Vascular Medicine (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

AT90202172T 1989-09-07 1990-08-10 Topisch anzuwendende defibrotid enthaltende arzneizubereitungen. ATE97001T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
IT8921651A IT1231509B (it)	1989-09-07	1989-09-07	Composizione farmceutica ad uso topico per la terapia della fragilita' capillare.

Publications (1)

Publication Number	Publication Date
ATE97001T1 true ATE97001T1 (de)	1993-11-15

Family

ID=11184862

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT90202172T ATE97001T1 (de)	1989-09-07	1990-08-10	Topisch anzuwendende defibrotid enthaltende arzneizubereitungen.

Country Status (12)

Country	Link
US (1)	US5116617A (de)
EP (1)	EP0416678B1 (de)
JP (1)	JPH0399019A (de)
KR (1)	KR910005876A (de)
AT (1)	ATE97001T1 (de)
AU (1)	AU623028B2 (de)
CA (1)	CA2021874A1 (de)
DE (1)	DE69004532T2 (de)
DK (1)	DK0416678T3 (de)
ES (1)	ES2045768T3 (de)
IT (1)	IT1231509B (de)
PT (1)	PT95212B (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1147777A1 (de) *	2000-04-18	2001-10-24	Crinos Industria Farmacobiologica S.p.A.	Kombination von Defibrotid und G-CSF und ihre Verwendung zur Aktivierung der hämatopoiestischen Vorläuferzellen
US8771663B2 (en)	2000-04-18	2014-07-08	Gentium Spa	Formulation having mobilising activity
US7029657B2 (en) *	2002-08-02	2006-04-18	Balance Pharmaceuticals, Inc.	Nasal spray steroid formulation and method
EP1872787A1 (de) *	2006-06-27	2008-01-02	Gentium S.p.A.	Verwendung von Defibrotide als Heparanasehemmer
EP2103689A1 (de)	2008-03-19	2009-09-23	Gentium S.p.A.	Synthetische Phosphodiester-Oligonukleotide und deren therapeutische Verwendungen
EP2637672B1 (de)	2010-11-12	2018-08-22	Gentium S.r.l.	Defibrotid zur prophylaxe und/oder behandlung von graft-versus-host-reaktion (gvhr)
KR102038357B1 (ko)	2012-06-22	2019-10-31	젠티엄 에스알엘	디파이브로타이드의 생물학적 활성 측정을 위한 유우글로불린에 기초한 방법
EP3026122A1 (de)	2014-11-27	2016-06-01	Gentium S.p.A.	Zellenbasiertes Verfahren zur Bestimmung der Wirksamkeit von Defibrotid
EP3661484A1 (de)	2017-08-03	2020-06-10	Jazz Pharmaceuticals Ireland Limited	Formulierungen mit einer nukleinsäure in hoher konzentration
WO2019200251A1 (en)	2018-04-12	2019-10-17	Jazz Pharmaceuticals, Inc.	Defibrotide for the prevention and treatment of cytokine release syndrome and neurotoxicity associated with immunodepletion
WO2020118165A1 (en)	2018-12-07	2020-06-11	Jazz Pharmaceuticals Ireland Limited	Subcutaneous delivery of high concentration formulations
US20230190783A1 (en)	2020-02-28	2023-06-22	Jazz Pharmaceuticals Ireland Limited	Delivery of low viscosity formulations
US20230086833A1 (en)	2020-04-17	2023-03-23	Jazz Pharmaceuticals Ireland Limited	Defibrotide treatment for the prevention of organ rejection and injury
TW202308659A (zh)	2021-05-06	2023-03-01	愛爾蘭商爵士製藥愛爾蘭有限責任公司	用於急性呼吸窘迫症候群之治療及預防的去纖維蛋白多核苷酸

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2154279A1 (de) *	1970-11-03	1972-05-25	Crinos Industria Farmaco	Medikamente für das fibrinolytische System
IT1043823B (it) *	1970-11-03	1980-02-29	Prephar	Procedimento per l estrazione di acidi nucleici da organi animali
IT1170215B (it) *	1983-09-12	1987-06-03	Crinos Industria Farmaco	Composizione farmaceutica per il trattamento di stati di insufficienza renale acuta
IT1170214B (it) *	1983-09-12	1987-06-03	Crinos Industria Farmaco	Composizione farmaceutica per la cura delle arteriopatie periferiche
IT1206341B (it) *	1984-02-16	1989-04-14	Crinos Industria Farmaco	Composizione farmaceutica per il trattamento dell'ischemia acuta del miocardio.

1989
- 1989-09-07 IT IT8921651A patent/IT1231509B/it active
1990
- 1990-07-20 AU AU59173/90A patent/AU623028B2/en not_active Ceased
- 1990-07-24 CA CA002021874A patent/CA2021874A1/en not_active Abandoned
- 1990-08-10 KR KR1019900012316A patent/KR910005876A/ko not_active Abandoned
- 1990-08-10 ES ES90202172T patent/ES2045768T3/es not_active Expired - Lifetime
- 1990-08-10 DE DE90202172T patent/DE69004532T2/de not_active Expired - Fee Related
- 1990-08-10 EP EP90202172A patent/EP0416678B1/de not_active Expired - Lifetime
- 1990-08-10 DK DK90202172.4T patent/DK0416678T3/da active
- 1990-08-10 AT AT90202172T patent/ATE97001T1/de not_active IP Right Cessation
- 1990-08-16 US US07/568,126 patent/US5116617A/en not_active Expired - Fee Related
- 1990-09-03 JP JP2230745A patent/JPH0399019A/ja active Pending
- 1990-09-05 PT PT95212A patent/PT95212B/pt not_active IP Right Cessation

Also Published As

Publication number	Publication date
CA2021874A1 (en)	1991-03-08
ES2045768T3 (es)	1994-01-16
EP0416678B1 (de)	1993-11-10
DE69004532D1 (de)	1993-12-16
DK0416678T3 (da)	1993-12-20
PT95212A (pt)	1991-05-22
JPH0399019A (ja)	1991-04-24
EP0416678A1 (de)	1991-03-13
IT1231509B (it)	1991-12-07
KR910005876A (ko)	1991-04-27
AU623028B2 (en)	1992-04-30
US5116617A (en)	1992-05-26
DE69004532T2 (de)	1994-02-24
IT8921651A0 (it)	1989-09-07
AU5917390A (en)	1991-03-14
PT95212B (pt)	1997-06-30

Legal Events

Date	Code	Title	Description
1994-09-15	UEP	Publication of translation of european patent specification
1999-05-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
DE122004000023I2 (de)	2009-05-07	Pharmazeutische Zusammensetzung
DE3863963D1 (de)	1991-09-05	Pharmazeutische zusammensetzungen.
DE68901417D1 (de)	1992-06-11	Pharmazeutische zusammensetzung.
SE8801813L (sv)	1988-11-15	Pharmaceutical composition
FI940850A7 (fi)	1994-03-09	Laite lääkkeen annostelemiseksi ihon kautta
FI922364A0 (fi)	1992-05-22	Farmaceutiska kompositioner.
FR2649613B1 (fr)	1991-09-27	Medicament vaso-actif
FI873113L (fi)	1988-01-16	Tvaettmedelskomposition.
IT8622683A0 (it)	1986-12-15	Dispositivo terapeutico per la somministrazione di medicamenti.
NO863029D0 (no)	1986-07-28	Farmasoeytisk doseringsenhet.
DK360188D0 (da)	1988-06-29	Laegemiddelafgivelsesorgan
IT8820386A0 (it)	1988-04-29	Composizioni farmaceutiche orosolubili contenti acetilcisteina.
DK0416678T3 (da)	1993-12-20	Topiske præparater indeholdende Defibrotid
DE3583765D1 (de)	1991-09-19	Hydantoinderivate und diese enthaltende pharmazeutische zusammensetzungen.
FI883673A0 (fi)	1988-08-05	Farmaceutiska kompositioner.
FI863618A7 (fi)	1987-03-12	Laekemedel foer haestar.
NO870533D0 (no)	1987-02-11	Terapeutisk aktive 3-alkoksy-2-aminopropylaminer.
NO900297L (no)	1990-07-24	Vaeskeformig farmasoeytisk preparat inneholdende piperidinoalkanolderivater.
FI851567A7 (fi)	1985-11-11	Lääkeruiskun annostelulaite.
DE68907609D1 (de)	1993-08-19	Arzneimittelzusammensetzung.
DE3866789D1 (de)	1992-01-23	Pharmazeutische zusammensetzungen.
IT8722647A0 (it)	1987-11-13	Composizione farmaceutica per somministrazione nasale.
ATE78161T1 (de)	1992-08-15	4-aroylimidazol-2-on enthaltende pharmazeutische zusammensetzung.
DE3667915D1 (de)	1990-02-08	Pharmazeutische zusammensetzung.
IT1215261B (it)	1990-01-31	Composizioni farmaceutiche adattivita' antigalattopoietica.