ATE99317T1 - Verfahren zur chlorierung von zuckern. - Google Patents

Verfahren zur chlorierung von zuckern.

Info

Publication number: ATE99317T1
Authority: AT; Austria
Prior art keywords: reaction; thionyl chloride; groups; sugar; partly protected
Prior art date: 1988-08-03

Application number

AT89307933T

Other languages

English (en)

Inventor

Nigel John Homer

Graham Jackson

George Henry Sankey

Philip John Simpson

Original Assignee

Tate & Lyle Plc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-08-03

Filing date

1989-08-03

Publication date

1994-01-15

1989-08-03 Application filed by Tate & Lyle Plc filed Critical Tate & Lyle Plc

1994-01-15 Application granted granted Critical

1994-01-15 Publication of ATE99317T1 publication Critical patent/ATE99317T1/de

Links

238000000034 method Methods 0.000 title abstract 2
FYSNRJHAOHDILO-UHFFFAOYSA-N thionyl chloride Chemical compound ClS(Cl)=O FYSNRJHAOHDILO-UHFFFAOYSA-N 0.000 abstract 8
235000000346 sugar Nutrition 0.000 abstract 6
JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 abstract 4
238000006243 chemical reaction Methods 0.000 abstract 4
WCTKUENARPWTAY-UHFFFAOYSA-N ac1l9mss Chemical class OS(Cl)=O WCTKUENARPWTAY-UHFFFAOYSA-N 0.000 abstract 3
125000001309 chloro group Chemical group Cl* 0.000 abstract 2
238000006073 displacement reaction Methods 0.000 abstract 2
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
239000012442 inert solvent Substances 0.000 abstract 2
238000003780 insertion Methods 0.000 abstract 2
230000037431 insertion Effects 0.000 abstract 2
UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 abstract 2
150000003839 salts Chemical group 0.000 abstract 2
LSNNMFCWUKXFEE-UHFFFAOYSA-N Sulfurous acid Chemical group OS(O)=O LSNNMFCWUKXFEE-UHFFFAOYSA-N 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
230000015572 biosynthetic process Effects 0.000 abstract 1
125000004432 carbon atom Chemical group C* 0.000 abstract 1
239000000460 chlorine Substances 0.000 abstract 1
238000000354 decomposition reaction Methods 0.000 abstract 1
125000001183 hydrocarbyl group Chemical group 0.000 abstract 1
238000002955 isolation Methods 0.000 abstract 1
150000008163 sugars Chemical class 0.000 abstract 1
239000000725 suspension Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
- C07H5/02—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to halogen
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H11/00—Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Health & Medical Sciences (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Life Sciences & Earth Sciences (AREA)
Saccharide Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Glass Compositions (AREA)
Iron Core Of Rotating Electric Machines (AREA)

AT89307933T 1988-08-03 1989-08-03 Verfahren zur chlorierung von zuckern. ATE99317T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB888818430A GB8818430D0 (en)	1988-08-03	1988-08-03	Process
EP89307933A EP0354050B1 (de)	1988-08-03	1989-08-03	Verfahren zur Chlorierung von Zuckern

Publications (1)

Publication Number	Publication Date
ATE99317T1 true ATE99317T1 (de)	1994-01-15

Family

ID=10641538

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT89307933T ATE99317T1 (de)	1988-08-03	1989-08-03	Verfahren zur chlorierung von zuckern.

Country Status (13)

Country	Link
US (1)	US4977254A (de)
EP (1)	EP0354050B1 (de)
JP (1)	JP3055910B2 (de)
KR (1)	KR0137951B1 (de)
AT (1)	ATE99317T1 (de)
CA (1)	CA1316532C (de)
DE (1)	DE68911788T2 (de)
DK (1)	DK170805B1 (de)
ES (1)	ES2062010T3 (de)
GB (2)	GB8818430D0 (de)
IE (1)	IE61917B1 (de)
PT (1)	PT91357B (de)
RU (1)	RU1836375C (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0373118A3 (de) *	1988-12-07	1991-10-16	Ciba-Geigy Ag	Verfahren zur Herstellung von geschützten Mono- und Oligozuckerhalogeniden
US5136031A (en) *	1990-07-09	1992-08-04	Tate & Lyle Public Limited Company	Chlorination of sugars
DE4227752A1 (de) *	1992-08-21	1994-02-24	Basf Ag	Verfahren zur Herstellung von Alkylglykosiden
US6555677B2 (en) *	2000-10-31	2003-04-29	Merck & Co., Inc.	Phase transfer catalyzed glycosidation of an indolocarbazole
EP1339728B1 (de)	2000-11-17	2013-02-27	Tate & Lyle Technology Limited	Verbesserte sucralose enthaltende zusammensetzung und verfahren zur kristallisation von sucralose
US6943248B2 (en)	2003-04-30	2005-09-13	Tate & Lyle Public Limited Company	Crystalline form of sucralose, and method for producing it
US20050214425A1 (en) *	2004-03-23	2005-09-29	Roma Vazirani	Sugar substitute prepared with nutritive and high-intensity sweeteners
GB2417555A (en) *	2004-07-28	2006-03-01	John Charles Fry	Sucralose analysis
US20060247180A1 (en) *	2005-04-29	2006-11-02	Bergey James L	Purgative composition and uses thereof
US20100222568A1 (en) *	2005-08-30	2010-09-02	Rakesh Ratnam	Removal of pyridine and pyridine analogs from reaction mass containing sucrose esters
US7741477B2 (en) *	2006-01-10	2010-06-22	Alembic Limited	Process for purification of sucralose
CN1814609B (zh) *	2006-03-06	2010-11-10	盐城捷康三氯蔗糖制造有限公司	一种提高三氯蔗糖合成收率的方法
CA2656797A1 (en) *	2006-07-06	2008-01-10	Alembic Limited	An improved process for the preparation of sucralose of high purity
US8258291B2 (en) *	2006-10-25	2012-09-04	Mamtek International Limited	Process for the preparation of sucralose by the chlorination of sugar with triphosgene (BTC)
US20080103295A1 (en) *	2006-10-25	2008-05-01	David Losan Ho	Process for the preparation of sucrose-6-ester by esterification in the presence of solid superacid catalyst
JP5337046B2 (ja) *	2006-12-05	2013-11-06	テートアンドライルテクノロジーリミテッド	トリチルクロライド回収
CN100591684C (zh) *	2006-12-27	2010-02-24	盐城捷康三氯蔗糖制造有限公司	三氯蔗糖结晶方法
KR20080073879A (ko) *	2007-02-07	2008-08-12	주식회사 일신케미칼	수크랄로오스의 제조방법
CN101260126B (zh) *	2007-03-06	2010-12-22	盐城捷康三氯蔗糖制造有限公司	三氯蔗糖的结晶方法
US20080300392A1 (en) *	2007-06-04	2008-12-04	Polymed Therapeutics, Inc.	Novel chlorination process for preparing sucralose
US20080300401A1 (en) *	2007-06-04	2008-12-04	Polymed Therapeutics, Inc.	Novel chlorination process for preparing sucralose
US7932380B2 (en) *	2008-03-06	2011-04-26	Wanhe International (Group) Co. Ltd.	Process for the preparation of sucralose
US20100022765A1 (en) *	2008-07-23	2010-01-28	David Losan Ho	Methods for extracting and purifying sucralose intermediate
CN102241708B (zh) *	2011-05-10	2013-10-30	山东大学	一种半乳糖苷化合物及其制备方法
CN105153247B (zh) *	2015-08-28	2017-11-21	山东康宝生化科技有限公司	一种解决固体光气法合成三氯蔗糖酯时蔗糖酯结块的方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB2036007A (en) *	1978-10-18	1980-06-25	Tate & Lyle Ltd	A Method for the Preparation of 2-chloro-2-deoxy Saccharides
EP0031651B1 (de) *	1979-12-20	1983-03-23	TATE & LYLE PUBLIC LIMITED COMPANY	Verfahren zur Herstellung von 4,1',6'-Trichlor-4,1',6'-trideoxy-galactosucrose
DE3165986D1 (en) *	1980-07-08	1984-10-18	Tate & Lyle Plc	Process for the preparation of 4, 1',6'-trichloro-4,1',6'-trideoxygalactosucrose (tgs)
DE3102516A1 (de) *	1981-01-27	1982-08-12	Hoechst Ag, 6000 Frankfurt	Verfahren zur herstellung von optisch aktiven 2-chlorpropionsaeureestern
ATE10003T1 (de) *	1981-08-21	1984-11-15	Tate & Lyle Public Limited Company	4'-halogen-substituierte sucrosederivate.
US4605784A (en)	1984-12-19	1986-08-12	Eastman Kodak Company	Process for the preparation of ether-containing chlorides
GB8500862D0 (en) *	1985-01-14	1985-02-20	Tate & Lyle Plc	Composition
GB8525871D0 (en) *	1985-10-21	1985-11-27	Tate & Lyle Plc	Chemical compound
GB8525954D0 (en) *	1985-10-21	1985-11-27	Mcneilab Inc	Chlorination of carbohydrates &c alcohols

1988
- 1988-08-03 GB GB888818430A patent/GB8818430D0/en active Pending
1989
- 1989-07-31 GB GB8917468A patent/GB2221462B/en not_active Expired - Lifetime
- 1989-08-02 CA CA000607337A patent/CA1316532C/en not_active Expired - Lifetime
- 1989-08-02 US US07/388,657 patent/US4977254A/en not_active Expired - Lifetime
- 1989-08-02 IE IE249889A patent/IE61917B1/en not_active IP Right Cessation
- 1989-08-02 DK DK379389A patent/DK170805B1/da not_active IP Right Cessation
- 1989-08-02 RU SU894614838A patent/RU1836375C/ru active
- 1989-08-03 EP EP89307933A patent/EP0354050B1/de not_active Expired - Lifetime
- 1989-08-03 KR KR1019890011119A patent/KR0137951B1/ko not_active Expired - Fee Related
- 1989-08-03 ES ES89307933T patent/ES2062010T3/es not_active Expired - Lifetime
- 1989-08-03 AT AT89307933T patent/ATE99317T1/de not_active IP Right Cessation
- 1989-08-03 PT PT91357A patent/PT91357B/pt active IP Right Grant
- 1989-08-03 JP JP1202247A patent/JP3055910B2/ja not_active Expired - Lifetime
- 1989-08-03 DE DE89307933T patent/DE68911788T2/de not_active Expired - Lifetime

Also Published As

Publication number	Publication date
DE68911788D1 (de)	1994-02-10
IE892498L (en)	1990-02-03
GB8917468D0 (en)	1989-09-13
RU1836375C (ru)	1993-08-23
GB8818430D0 (en)	1988-09-07
EP0354050A3 (de)	1991-09-04
JP3055910B2 (ja)	2000-06-26
IE61917B1 (en)	1994-11-30
KR900003190A (ko)	1990-03-26
PT91357B (pt)	1995-05-04
GB2221462B (en)	1992-04-22
PT91357A (pt)	1990-03-08
GB2221462A (en)	1990-02-07
CA1316532C (en)	1993-04-20
DE68911788T2 (de)	1994-04-14
EP0354050B1 (de)	1993-12-29
KR0137951B1 (ko)	1998-04-30
DK379389D0 (da)	1989-08-02
US4977254A (en)	1990-12-11
DK379389A (da)	1990-02-04
EP0354050A2 (de)	1990-02-07
JPH02160796A (ja)	1990-06-20
ES2062010T3 (es)	1994-12-16
DK170805B1 (da)	1996-01-22

Legal Events

Date	Code	Title	Description
1994-09-15	UEP	Publication of translation of european patent specification
2004-05-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
ATE99317T1 (de)	1994-01-15	Verfahren zur chlorierung von zuckern.
ATE33494T1 (de)	1988-04-15	1,8-naphthyridinderivate und verfahren zu ihrer herstellung.
ES483511A1 (es)	1980-09-01	Un procedimiento para la preparaion de nuevas espiro-oxazo- lidinohoinas.
DK328188A (da)	1988-12-18	Pyridinderivater, deres fremstilling og laegemidler indeholdende forbindelserne
EP0667332A4 (de)	1995-12-27	Verfahren zur herstellung von fluorierten dicarbonylverbindungen.
KR840006482A (ko)	1984-11-30	디히드로피라졸로 [3,4-b]피리딘 유도체의 제조방법
ATE61577T1 (de)	1991-03-15	Fluorierte abkoemmlinge von vitamin-d3 und verfahren zu deren herstellung.
KR860009076A (ko)	1986-12-20	폴리이소시아네이트 유기용액의 안정화 방법
NO801615L (no)	1980-12-03	Stabiliserte halogenhydrocarboner.
KR900004754A (ko)	1990-04-12	수크로오스 또는 그 유도체의 염소화 방법 및 수크랄로오스의 제조 방법
DE3781189D1 (de)	1992-09-24	Verfahren zur herstellung von oxazinobenzothiazin-6,6-dioxidderivaten.
AU665980B2 (en)	1996-01-25	Process for producing prostaglandin E
ATE135693T1 (de)	1996-04-15	Halogeno-4-methylpyrazole und verfahren zu ihrer herstellung
ATE307794T1 (de)	2005-11-15	Verfahren zur herstellung von chlorcarbonsäurechloriden
AU537946B2 (en)	1984-07-19	Nicotinic derivatives of glucosamines
DE3879058D1 (de)	1993-04-15	4-piperidincarboxamid-derivate.
IE33955L (en)	1970-08-13	Penicillanic acids
GB2042540B (en)	1982-11-24	Process for the preparation of xanthone derivatives
CA2006665A1 (en)	1990-06-27	Process for purification of 1,2-bis (nicotinamido) propane
KR830002673A (ko)	1983-05-30	시클로프로판카르본산 에스테르의 제조 방법