AU710856B2 - The irs family of genes - Google Patents

The irs family of genes Download PDF

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Publication number
AU710856B2
AU710856B2 AU38301/95A AU3830195A AU710856B2 AU 710856 B2 AU710856 B2 AU 710856B2 AU 38301/95 A AU38301/95 A AU 38301/95A AU 3830195 A AU3830195 A AU 3830195A AU 710856 B2 AU710856 B2 AU 710856B2
Authority
AU
Australia
Prior art keywords
irs
ser
gly
pro
xaa xaa
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU38301/95A
Other languages
English (en)
Other versions
AU3830195A (en
Inventor
Jacalyn H. Pierce
Xiao Jian Sun
Morris F. White Jr.
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Joslin Diabetes Center Inc
US Department of Health and Human Services
Original Assignee
Joslin Diabetes Center Inc
US Department of Health and Human Services
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Joslin Diabetes Center Inc, US Department of Health and Human Services filed Critical Joslin Diabetes Center Inc
Publication of AU3830195A publication Critical patent/AU3830195A/en
Application granted granted Critical
Publication of AU710856B2 publication Critical patent/AU710856B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AU38301/95A 1994-10-03 1995-10-03 The irs family of genes Ceased AU710856B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/317310 1994-10-03
US08/317,310 US5858701A (en) 1994-10-03 1994-10-03 DNA encoding an insulin receptor substrate
PCT/US1995/013041 WO1996010629A1 (en) 1994-10-03 1995-10-03 The irs family of genes

Publications (2)

Publication Number Publication Date
AU3830195A AU3830195A (en) 1996-04-26
AU710856B2 true AU710856B2 (en) 1999-09-30

Family

ID=23233096

Family Applications (1)

Application Number Title Priority Date Filing Date
AU38301/95A Ceased AU710856B2 (en) 1994-10-03 1995-10-03 The irs family of genes

Country Status (6)

Country Link
US (1) US5858701A (de)
EP (1) EP0781326A4 (de)
JP (1) JPH11500601A (de)
AU (1) AU710856B2 (de)
CA (1) CA2201474A1 (de)
WO (1) WO1996010629A1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6054280A (en) * 1995-03-20 2000-04-25 Lemmon; Mark A. Methods for diagnosis and treatment of PH domain signal transduction disorders
AU7181198A (en) * 1996-11-13 1998-06-03 Receptron Corporation Assays for non-insulin dependent diabetes
US5891674A (en) * 1997-06-19 1999-04-06 Incyte Pharmaceuticals, Inc. Insulin receptor tyrosine kinase substrate
SE0002189D0 (sv) 2000-06-09 2000-06-09 Metcon Medicin Ab New method and assay
WO2001094410A1 (en) * 2000-06-08 2001-12-13 Metcon Medicin Ab Insulin regulated substance (irs-2) induced by pioglitazone, assay and use thereof
US20020051786A1 (en) * 2000-06-23 2002-05-02 Kahn C. Ronald Modulators of p85 expression
EP1581307B1 (de) * 2003-01-02 2014-09-24 Gerard M. Housey Irs-modulatoren
WO2005012234A1 (en) * 2003-07-30 2005-02-10 The Hospital For Sick Children Compounds for modulating cell proliferation
EP3461813A1 (de) * 2004-05-23 2019-04-03 Gerard M. Housey Theramuteinmodulatoren
US8431110B2 (en) 2005-05-23 2013-04-30 Hmi Medical Innovations, Llc. Compounds and method of identifying, synthesizing, optimizing and profiling protein modulators
CN103789389B (zh) * 2005-11-23 2017-01-04 杰勒德·M·豪斯 鉴定、合成、优化和表征蛋白调节剂的化合物和方法
US20070161006A1 (en) * 2006-01-10 2007-07-12 Vita Genomics, Inc. Single nucleotide polymorphisms in protein-tyrosine phosphatase receptor-type delta for the diagnosis of susceptibility to infection and asthma
CA2762987A1 (en) * 2009-05-22 2010-11-25 Joseph Collard Treatment of transcription factor e3 (tfe3) and insulin receptor substrate 2 (irs2) related diseases by inhibition of natural antisense transcript to tfe3
US8383591B2 (en) 2010-12-21 2013-02-26 Gene Signal International S.A. Peptides for treating cancer
CN103379913B (zh) * 2010-12-21 2015-11-25 基因信号国际公司 用于治疗癌症的肽
US20160022752A1 (en) 2013-03-12 2016-01-28 HMI Medical Innovations, LLC Plant extracts with anti-diabetic and other useful activities
JP2020519688A (ja) 2017-05-12 2020-07-02 ハウジー ファーマシューティカル リサーチ ラボラトリーズ、エル．エル．シー． 抗糖尿病活性および他の有用な活性を有する植物抽出物

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992013083A1 (en) * 1991-01-18 1992-08-06 Joslin Diabetes Center, Inc. Nucleic acid encoding insulin receptor substrate-1 (irs-1), irs-1 protein, diseases, therapy associated with the metabolism of irs-1
WO1994029345A1 (en) * 1993-06-10 1994-12-22 Novo Nordisk A/S Mutant dna encoding insulin receptor substrate 1

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5260200A (en) * 1991-01-18 1993-11-09 Joslin Diabetes Center, Inc. Isolated DNA encoding an insulin receptor substrate

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992013083A1 (en) * 1991-01-18 1992-08-06 Joslin Diabetes Center, Inc. Nucleic acid encoding insulin receptor substrate-1 (irs-1), irs-1 protein, diseases, therapy associated with the metabolism of irs-1
WO1994029345A1 (en) * 1993-06-10 1994-12-22 Novo Nordisk A/S Mutant dna encoding insulin receptor substrate 1

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NATURE, VOL.372, 10/11/1994, E.ARAKI ET.AL., PP.186-190 *

Also Published As

Publication number Publication date
AU3830195A (en) 1996-04-26
EP0781326A4 (de) 1999-10-06
US5858701A (en) 1999-01-12
JPH11500601A (ja) 1999-01-19
EP0781326A1 (de) 1997-07-02
WO1996010629A1 (en) 1996-04-11
CA2201474A1 (en) 1996-04-11

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Legal Events

Date Code Title Description
MK14 Patent ceased section 143(a) (annual fees not paid) or expired