BE1000723A4 - Utilisation de gangliosides exogenes dans des maladies tumorales comme facteur de protection contre la toxicite de medicaments antitumoraux. - Google Patents

Utilisation de gangliosides exogenes dans des maladies tumorales comme facteur de protection contre la toxicite de medicaments antitumoraux. Download PDF

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Publication number
BE1000723A4
BE1000723A4 BE8700719A BE8700719A BE1000723A4 BE 1000723 A4 BE1000723 A4 BE 1000723A4 BE 8700719 A BE8700719 A BE 8700719A BE 8700719 A BE8700719 A BE 8700719A BE 1000723 A4 BE1000723 A4 BE 1000723A4
Authority
BE
Belgium
Prior art keywords
tumor
factor against
protective factor
against toxicity
gangliosides
Prior art date
Application number
BE8700719A
Other languages
English (en)
Inventor
Valle Francesco Della
Original Assignee
Fidia Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fidia Spa filed Critical Fidia Spa
Application granted granted Critical
Publication of BE1000723A4 publication Critical patent/BE1000723A4/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Un agent de prévention et de prophylaxie des effets toxiques généraux ou des effets neurotoxiques chroniques occasionnés par l'administration d'agents antinéoplasiques, que l'on doit administrer aux patients avent l'administration de ces agents néoplasiques et qui comprend comme ingrédient actif un mélange de gangliosides GM1, GD1a, GD1b et GT1b.
BE8700719A 1986-06-30 1987-06-26 Utilisation de gangliosides exogenes dans des maladies tumorales comme facteur de protection contre la toxicite de medicaments antitumoraux. BE1000723A4 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8648203A IT1208751B (it) 1986-06-30 1986-06-30 Possibile uso dei gangliosidi esogeni in malattie tumorali come fattore protettivo contro la neurotossicita' da farmaci antitumorali

Publications (1)

Publication Number Publication Date
BE1000723A4 true BE1000723A4 (fr) 1989-03-21

Family

ID=11265194

Family Applications (1)

Application Number Title Priority Date Filing Date
BE8700719A BE1000723A4 (fr) 1986-06-30 1987-06-26 Utilisation de gangliosides exogenes dans des maladies tumorales comme facteur de protection contre la toxicite de medicaments antitumoraux.

Country Status (16)

Country Link
US (1) US5229373A (fr)
EP (1) EP0251298B1 (fr)
JP (1) JPS6327434A (fr)
AT (1) ATE69381T1 (fr)
AU (1) AU601988B2 (fr)
BE (1) BE1000723A4 (fr)
CA (1) CA1314219C (fr)
DE (2) DE3774501D1 (fr)
DK (1) DK165621C (fr)
ES (1) ES2038621T3 (fr)
FR (1) FR2601248B1 (fr)
GR (2) GR871005B (fr)
IL (1) IL82944A (fr)
IT (1) IT1208751B (fr)
LU (1) LU86930A1 (fr)
ZA (1) ZA874597B (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1254280B (it) * 1992-03-13 1995-09-14 Fidia Spa Composizioni farmaceutiche comprendenti monosialoganglioside gm1 o un suo derivato atte al trattamento della malattia di parkinson
US6765087B1 (en) * 1992-08-21 2004-07-20 Vrije Universiteit Brussel Immunoglobulins devoid of light chains
DE4430041A1 (de) † 1994-08-24 1996-02-29 Milupa Ag Allergieprotektive Formelnahrung
US5567684A (en) * 1994-09-14 1996-10-22 The Regents Of The University Of California Synthetic ganglioside derivatives
JP2005527467A (ja) 2001-08-29 2005-09-15 ネオーズ テクノロジーズ， インコーポレイテッド 新規な合成ガングリオシド誘導体およびその組成物
CA2518171C (fr) 2003-03-06 2013-07-09 Neose Technologies, Inc. Procedes et compositions pour la synthese enzymatique de gangliosides
KR20100127842A (ko) * 2008-03-26 2010-12-06 유니버시티 오브 옥스퍼드 소포체 표적화 리포좀
WO2010111530A1 (fr) 2009-03-25 2010-09-30 Seneb Biosciences, Inc. Glycolipides en tant que traitement de maladies
US20120148547A1 (en) * 2009-09-01 2012-06-14 Hadasit Medical Reasearch Services & Development Ltd. Combination of vitamin e and beta-glycosphingolipids in compositions and methods for preventing and treating hepatic disorders

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1168205B (it) * 1983-07-21 1987-05-20 Wellcome Italia Derivato di monsialo ganglioside dotato di attivita' antibatterica, antifungina ed antitumorale, composizioni che lo contengono e procedimento per la loro preparazione
IT1182209B (it) * 1985-02-18 1987-09-30 Fidia Farmaceutici Uso terapeutico del monosialoganglioside gm1 e dei suoi derivati in gravi patologie di infarti cerebrali

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
Chemical Abstracts, vol. 107, no. 15, 12 octobre 1987 (Columbus, Ohio, US) K. Hellmann et al.: "Effect of high dose mitozantrone with Cronassial on the Lewis lung carcinoma and L1210 leukemia", voir page 26 *
Chemical Abstracts, vol. 108, no. 23, 6 juin 1988 (Columbus, Ohio, US) K. Hellmann et al.: "Mitozantrone therapeutic index improvement by gangliosides", voir page 25 *
Chemical Abstracts, vol. 108, no. 5, 1er fevrier 1988, (Columbus, Ohio, US) K. Hellmann et al.: "Reduction of vincristine toxicity by Cronassial", voir page 37 *

Also Published As

Publication number Publication date
EP0251298A2 (fr) 1988-01-07
JPS6327434A (ja) 1988-02-05
ZA874597B (en) 1988-03-30
DK333787A (da) 1987-12-31
DK333787D0 (da) 1987-06-29
US5229373A (en) 1993-07-20
DK165621B (da) 1992-12-28
AU7490887A (en) 1988-01-07
GR871005B (en) 1987-10-23
IT8648203A0 (it) 1986-06-30
FR2601248B1 (fr) 1989-08-25
EP0251298B1 (fr) 1991-11-13
IT1208751B (it) 1989-07-10
IL82944A (en) 1993-04-04
AU601988B2 (en) 1990-09-27
FR2601248A1 (fr) 1988-01-15
LU86930A1 (fr) 1987-11-11
DE3774501D1 (de) 1991-12-19
DE3721562A1 (de) 1988-03-03
GR3003790T3 (fr) 1993-03-16
EP0251298A3 (en) 1988-10-26
DK165621C (da) 1993-06-01
ES2038621T3 (es) 1993-08-01
ATE69381T1 (de) 1991-11-15
CA1314219C (fr) 1993-03-09

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: FIDIA S.P.A.

Effective date: 19930630