BE1002109A3 - Composition pharmaceutique a activite analgesique. - Google Patents

Composition pharmaceutique a activite analgesique. Download PDF

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Publication number
BE1002109A3
BE1002109A3 BE8700823A BE8700823A BE1002109A3 BE 1002109 A3 BE1002109 A3 BE 1002109A3 BE 8700823 A BE8700823 A BE 8700823A BE 8700823 A BE8700823 A BE 8700823A BE 1002109 A3 BE1002109 A3 BE 1002109A3
Authority
BE
Belgium
Prior art keywords
pharmaceutical composition
analgesic activity
ibuprofen
arginine
usable
Prior art date
Application number
BE8700823A
Other languages
English (en)
Inventor
Annibale Gazzaniga
Walter Gianesello
Federico Stroppolo
Luigi Vigano
Original Assignee
Zambon Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zambon Spa filed Critical Zambon Spa
Application granted granted Critical
Publication of BE1002109A3 publication Critical patent/BE1002109A3/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0007—Effervescent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1611—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Neurosurgery (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

Une composition pharmaceutique formée de Ibuprofène 33-46% p/p, L'arginine 34-51 % p/p, Bicarbonate de sodium 9-29 % p/p est utilisable pour la confection de préparations pharmaceutiques sous forme de granulés solubles dans l'eau.
BE8700823A 1986-08-01 1987-07-24 Composition pharmaceutique a activite analgesique. BE1002109A3 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT21358/86A IT1197038B (it) 1986-08-01 1986-08-01 Composizione farmaceutica ad attivita' analgesica

Publications (1)

Publication Number Publication Date
BE1002109A3 true BE1002109A3 (fr) 1990-07-10

Family

ID=11180633

Family Applications (1)

Application Number Title Priority Date Filing Date
BE8700823A BE1002109A3 (fr) 1986-08-01 1987-07-24 Composition pharmaceutique a activite analgesique.

Country Status (17)

Country Link
US (1) US4834966A (fr)
JP (1) JP2585005B2 (fr)
AT (1) AT394945B (fr)
AU (1) AU595342B2 (fr)
BE (1) BE1002109A3 (fr)
BG (1) BG60832B2 (fr)
CA (1) CA1286992C (fr)
CH (1) CH673394A5 (fr)
DE (1) DE3725176C2 (fr)
FR (1) FR2602141B1 (fr)
GB (1) GB2193093B (fr)
GR (1) GR871197B (fr)
IE (1) IE60276B1 (fr)
IT (1) IT1197038B (fr)
MX (1) MX9203167A (fr)
NL (1) NL194031C (fr)
ZA (1) ZA875397B (fr)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4861797A (en) * 1987-10-15 1989-08-29 Oratech Pharmaceutical Development Corporation Liquid ibuprofen compositions and methods of making them
JPH0256416A (ja) * 1988-08-19 1990-02-26 Daikyo Yakuhin Kogyo Kk 苦味を抑えた顆粒剤
DE3922441A1 (de) * 1989-07-07 1991-01-17 Pharmatrans Sanaq Ag Ibuprofen- und s-(+)-ibuprofen-zubereitungen und verfahren zu ihrer herstellung
US5262179A (en) * 1989-09-13 1993-11-16 Nicholas Kiwi Pty Ltd. Non-effervescent ibuprofen compositions
GB8920693D0 (en) * 1989-09-13 1989-10-25 Nicholas Kiwi Pty Ltd Non-effervescent ibuprofen compositions
IT1245890B (it) * 1991-04-12 1994-10-25 Alfa Wassermann Spa Formulazioni farmaceutiche per uso orale gastroresistenti contenenti acidi biliari.
IT1272149B (it) * 1993-03-26 1997-06-11 Zambon Spa Composizione farmeceutiche ad attivita' analgesica
IT1264855B1 (it) * 1993-06-21 1996-10-17 Zambon Spa Composizioni farmaceutiche contenenti sali dell'acido s(+)-2-(4-isobutilfenil) propionico con amminoacidi basici
IT1264856B1 (it) * 1993-06-21 1996-10-17 Zambon Spa Composizione farmaceutica ad attivita' analgesica
IT1264857B1 (it) 1993-06-21 1996-10-17 Zambon Spa Composizione farmaceutica liquida per uso orale contenente acido 2-(4-isobutilfenil) propionico
IT1266583B1 (it) * 1993-07-30 1997-01-09 Zambon Spa Processo per la preparazione di sali dell'acido 2-(4-isobutilfenil)- propionico
DE19502789A1 (de) * 1995-01-28 1996-08-01 Dirk Krischenowski Arzneimittel
DE19606151C2 (de) * 1996-02-20 1999-05-12 Losan Pharma Gmbh Ibuprofen-Brausezubereitung sowie Verfahren zur Herstellung derselben
DE19800812C2 (de) * 1998-01-12 2000-05-11 Juergen C Froelich Verbesserte orale Darreichungsformen von L-Arginin-HCl
IT1301966B1 (it) * 1998-07-30 2000-07-20 Zambon Spa Composizioni farmaceutiche ad attivita' analgesica
WO2001022939A1 (fr) * 1999-09-29 2001-04-05 Fmc Corporation Granulations par cellulose hydrolyzee de sels de medicaments
WO2002019833A2 (fr) * 2000-09-07 2002-03-14 Akpharma Inc. Compositions de bonbons comestibles et procede d'utilisation de ces dernieres
US20020099037A1 (en) * 2001-01-19 2002-07-25 Akpharma, Inc. Method for alleviating syndromes and conditions of discomfort of the mammalian intestinal and genito-urinary tracts
WO2002069936A2 (fr) * 2001-03-02 2002-09-12 Dr. Reddy's Laboratories Ltd. Composition pharmaceutique amelioree d'ibuprofene et procede de production de telles compositions
US20030008003A1 (en) * 2001-04-10 2003-01-09 Fahkreddin Jamali Compositions for enhanced absorption of NSAIDs
US6727286B2 (en) 2001-11-02 2004-04-27 Cumberland Pharmaceuticals Inc. Pharmaceutical composition of 2-(4-isobutylphenyl) propionic acid
BRPI0409127A (pt) * 2003-04-11 2006-03-28 Pfizer combinação farmacêutica compreendendo eletriptano e bicarbonato de sódio
JP4913359B2 (ja) * 2004-05-07 2012-04-11 第一三共ヘルスケア株式会社 イブプロフェン含有医薬組成物
WO2005115345A1 (fr) 2004-05-28 2005-12-08 Imaginot Pty Ltd Systeme d'administration orale de compose therapeutique
US8216610B2 (en) * 2004-05-28 2012-07-10 Imaginot Pty Ltd. Oral paracetamol formulations
EP1800667A1 (fr) 2005-12-23 2007-06-27 Losan Pharma GmbH Granulate d'ibuprofen solubilisé rapidement
RU2403033C2 (ru) 2005-03-22 2010-11-10 Лозан Фарма Гмбх Солюбилизированный ибупрофен
EP3263117A1 (fr) 2005-11-28 2018-01-03 Imaginot Pty Ltd. Système d'administration d'un composé thérapeutique oral
ES2303468B1 (es) * 2007-01-22 2009-06-08 Masterfarm, S.L "una composicion farmaceutica pulverulenta que comprende ibuprofeno".
RU2715680C2 (ru) * 2009-06-22 2020-03-03 ВАЙЕТ ЭлЭлСи Таблетки ибупрофена натрия и способы изготовления фармацевтических композиций, включающих ибупрофен натрия
ES2353541B1 (es) 2009-07-30 2011-09-20 Farmalider, S.A. Combinacion de ingredientes activos cosmeticos y composicion cosmetica obtenida a partir de la misma, y su utilizacion.
CN101810568A (zh) * 2010-03-29 2010-08-25 南京泛太化工医药研究所 含有布洛芬的注射剂及其制备方法
MX2010004974A (es) * 2010-05-04 2011-11-23 Senosiain S A De C V Lab Combinacion de un aine y un aminoacido.

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2508895A1 (de) * 1974-03-07 1975-09-18 Prodotti Antibiotici Spa Salze von phenylalkancarbonsaeuren mit basischen aminosaeuren
EP0172014A2 (fr) * 1984-08-17 1986-02-19 The Upjohn Company Formulations à base d'ibuprofène
DE3638414A1 (de) * 1985-11-12 1987-05-21 Zambon Spa Brausezusammensetzung mit analgetischer wirkung

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2036890B1 (fr) * 1969-04-15 1973-01-12 Orsymonde
US4294819A (en) * 1980-08-18 1981-10-13 Bristol-Myers Company Alkaline analgesic capsule
DE3328401A1 (de) * 1983-08-05 1985-02-21 Merckle GmbH, 7902 Blaubeuren Injizierbare loesung zur behandlung von entzuendungen
US4569937A (en) * 1985-02-11 1986-02-11 E. I. Du Pont De Nemours And Company Analgesic mixture of oxycodone and ibuprofen
GB8528195D0 (en) * 1985-11-15 1985-12-18 Boots Co Plc Therapeutic compositions

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2508895A1 (de) * 1974-03-07 1975-09-18 Prodotti Antibiotici Spa Salze von phenylalkancarbonsaeuren mit basischen aminosaeuren
EP0172014A2 (fr) * 1984-08-17 1986-02-19 The Upjohn Company Formulations à base d'ibuprofène
DE3638414A1 (de) * 1985-11-12 1987-05-21 Zambon Spa Brausezusammensetzung mit analgetischer wirkung

Also Published As

Publication number Publication date
CH673394A5 (fr) 1990-03-15
FR2602141A1 (fr) 1988-02-05
BG60832B2 (bg) 1996-04-30
DE3725176C2 (de) 1995-06-14
AT394945B (de) 1992-07-27
NL194031B (nl) 2001-01-02
IE871745L (en) 1988-02-01
FR2602141B1 (fr) 1990-11-30
JPS6341420A (ja) 1988-02-22
AU595342B2 (en) 1990-03-29
CA1286992C (fr) 1991-07-30
ZA875397B (en) 1988-02-01
GB2193093B (en) 1990-03-28
IT8621358A0 (it) 1986-08-01
NL194031C (nl) 2001-05-03
AU7554087A (en) 1988-02-04
ATA187887A (de) 1992-01-15
GB8716301D0 (en) 1987-08-19
JP2585005B2 (ja) 1997-02-26
US4834966A (en) 1989-05-30
DE3725176A1 (de) 1988-02-04
MX9203167A (es) 1992-07-01
NL8701729A (nl) 1988-03-01
IE60276B1 (en) 1994-06-29
IT8621358A1 (it) 1988-02-01
IT1197038B (it) 1988-11-25
GR871197B (en) 1987-12-04
GB2193093A (en) 1988-02-03

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Legal Events

Date Code Title Description
RE20 Patent expired

Owner name: S.A. *INPHARZAM

Effective date: 20070724