BE2022C521I2 - - Google Patents

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Publication number
BE2022C521I2
BE2022C521I2 BE2022C521C BE2022C521C BE2022C521I2 BE 2022C521 I2 BE2022C521 I2 BE 2022C521I2 BE 2022C521 C BE2022C521 C BE 2022C521C BE 2022C521 C BE2022C521 C BE 2022C521C BE 2022C521 I2 BE2022C521 I2 BE 2022C521I2
Authority
BE
Belgium
Application number
BE2022C521C
Other languages
Dutch (nl)
Original Assignee
Siga Tech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Siga Tech Inc filed Critical Siga Tech Inc
Publication of BE2022C521I2 publication Critical patent/BE2022C521I2/nl

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/58[b]- or [c]-condensed
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
BE2022C521C 2003-06-20 2022-05-30 BE2022C521I2 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US48018203P 2003-06-20 2003-06-20

Publications (1)

Publication Number Publication Date
BE2022C521I2 true BE2022C521I2 (es) 2024-04-23

Family

ID=33539267

Family Applications (1)

Application Number Title Priority Date Filing Date
BE2022C521C BE2022C521I2 (es) 2003-06-20 2022-05-30

Country Status (11)

Country Link
EP (1) EP1638938B1 (es)
JP (2) JP4884216B2 (es)
AU (1) AU2004249250C1 (es)
BE (1) BE2022C521I2 (es)
CA (1) CA2529761C (es)
DK (1) DK1638938T3 (es)
ES (1) ES2632313T3 (es)
FR (1) FR22C1022I1 (es)
NL (1) NL301177I2 (es)
PL (1) PL1638938T3 (es)
WO (1) WO2004112718A2 (es)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8530509B2 (en) 2003-06-20 2013-09-10 Siga Technologies, Inc. Compounds, compositions and methods for treatment and prevention of orthopoxvirus infections and associated diseases
US7737168B2 (en) 2003-06-20 2010-06-15 Siga Technologies, Inc. Compounds, compositions, and methods for treatment and prevention of orthopoxvirus infections and associated diseases
EP1638938B1 (en) * 2003-06-20 2017-04-12 Siga Technologies Inc. Compounds, compositions and methods for treatment and prevention of orthopoxvirus infections and associated diseases
AU2012268859B2 (en) * 2003-06-20 2016-05-05 Siga Technologies, Inc. Chemicals, compositions, and methods for treatment and prevention of orthopoxvirus infections and associated diseases
CA2576850C (en) * 2004-08-30 2013-06-25 Janssen Pharmaceutica N.V. Tricyclic lactam derivatives as 11-beta hydroxysteroid dehydrogenase inhibitors
US8410149B2 (en) 2004-12-06 2013-04-02 Siga Technologies Inc. Sulfonyl semicarbazides, semicarbazides and ureas, pharmaceutical compositions thereof, and methods for treating hemorrhagic fever viruses, including infections associated with arenaviruses
AU2005314252B2 (en) 2004-12-06 2012-09-27 Siga Technologies, Inc. Compounds and methods for treating hemorrhagic fever viruses
US7994221B2 (en) 2004-12-06 2011-08-09 Siga Technologies, Inc. Sulfonyl semicarbazides, carbonyl semicarbazides, semicarbazides and ureas, pharmaceutical compositions thereof, and methods for treating hemorrhagic fever viruses, including infections associated with arenaviruses
EP2842559A3 (en) * 2005-04-08 2015-03-18 Chimerix, Inc. Compounds, compositions and methods for the treatment of viral infections and other medical disorders
US8642577B2 (en) * 2005-04-08 2014-02-04 Chimerix, Inc. Compounds, compositions and methods for the treatment of poxvirus infections
CN104758281A (zh) * 2007-04-23 2015-07-08 西佳技术公司 用于治疗和预防正痘病毒感染和相关疾病的化合物、组合物和方法
ES2572631T3 (es) 2008-01-25 2016-06-01 Chimerix, Inc. Métodos de tratamiento de infecciones virales
WO2011011519A1 (en) 2009-07-21 2011-01-27 Chimerix, Inc. Compounds, compositions and methods for treating ocular conditions
RU2412167C1 (ru) * 2009-12-02 2011-02-20 Федеральное государственное учреждение науки "Государственный научный центр вирусологии и биотехнологии "Вектор" Федеральной службы по надзору в сфере защиты прав потребителей и благополучия человека (ФГУН ГНЦ ВБ "Вектор" Роспотребнадзора) {3,5-диоксо-4-азатетрацикло[5.3.2.02,6.08,10]додец-11-ен-4-ил}тиомочевина, обладающая противовирусной активностью в отношении ортопоксвирусов
RU2412168C1 (ru) * 2009-12-02 2011-02-20 Федеральное государственное учреждение науки "Государственный научный центр вирусологии и биотехнологии "Вектор" Федеральной службы по надзору в сфере защиты прав потребителей и благополучия человека (ФГУН ГНЦ ВБ "Вектор" Роспотребнадзора) Гидрат n-{3,5-диоксо-4-азатетрацикло[5.3.2.02,6.08,10]додец-11-ен-4-ил}-2-гидроксибензамида, обладающий противовирусной активностью в отношении ортопоксвирусов
US9006218B2 (en) 2010-02-12 2015-04-14 Chimerix Inc. Nucleoside phosphonate salts
JP6018041B2 (ja) 2010-03-23 2016-11-02 シガ・テクノロジーズ・インコーポレーテッド St−246の多形型および調製方法
CA2797601A1 (en) 2010-04-26 2011-11-10 Chimerix, Inc. Methods of treating retroviral infections and related dosage regimes
CA2807528C (en) * 2010-08-05 2018-09-25 Siga Technologies, Inc. St-246 liquid formulations and methods
CN101906064A (zh) * 2010-08-09 2010-12-08 中国人民解放军军事医学科学院微生物流行病研究所 St-246的立体异构体的制备方法
RU2440983C1 (ru) * 2010-09-28 2012-01-27 Новосибирский институт органической химии им. Н.Н. Ворожцова Сибирского отделения Российской академии наук (НИОХ СО РАН) Метил, хлор и нитропроизводные n-{3, 5-диоксо-4-азатетрацикло[5.3.2.02,6.08,10]додец-11-ен-4-ил}-2-гидроксибензамида-противовирусные препараты, ингибирующие репликацию различных видов ортопоксвирусов
CN107235890B (zh) 2012-08-16 2020-03-06 西佳技术公司 制备特考韦瑞的方法
WO2015009566A1 (en) 2013-07-19 2015-01-22 Siga Technologies, Inc. Amorphous tecovirimat preparation
KR20240167861A (ko) * 2022-03-27 2024-11-28 보드 오브 리전츠, 더 유니버시티 오브 텍사스 시스템 라노스테롤 합성효소의 소분자 억제제
CN116730995B (zh) * 2022-08-12 2024-06-25 深圳微芯生物科技股份有限公司 一类酰肼类化合物、其制备方法及其应用
CN116003309B (zh) * 2022-08-12 2025-03-04 深圳微芯生物科技股份有限公司 一类酰肼类化合物、其制备方法及其应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2906755A (en) * 1956-11-16 1959-09-29 Schenley Ind Inc N-acyl derivatives of alpha-pyridine carboxylic acid hydrazide
US4061763A (en) * 1975-05-09 1977-12-06 Merck & Co., Inc. Tricyclicdicarboximides
JPS5247844A (en) * 1975-10-15 1977-04-16 Ube Ind Ltd Elastomer compositions
JPS6483065A (en) * 1987-09-25 1989-03-28 Hitachi Chemical Co Ltd Endo-cis-3,6-cyclopropylene-tetra(or hexa)hydrophthalic acid imide derivative and antiarhythmic agent
US5068356A (en) * 1990-02-20 1991-11-26 Atochem North America, Inc. Hindered phenolic n-(amido)imides
US6596771B2 (en) 2001-01-12 2003-07-22 Schering Corporation Drugs for treating viral infections
US6433016B1 (en) 2001-01-12 2002-08-13 Vassil Stefanov Georgiev Drugs for treating viral infections
US20040087548A1 (en) * 2001-02-27 2004-05-06 Salvati Mark E. Fused cyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
EP1638938B1 (en) * 2003-06-20 2017-04-12 Siga Technologies Inc. Compounds, compositions and methods for treatment and prevention of orthopoxvirus infections and associated diseases

Also Published As

Publication number Publication date
JP4884216B2 (ja) 2012-02-29
AU2004249250B2 (en) 2011-09-01
WO2004112718A2 (en) 2004-12-29
EP1638938A4 (en) 2008-09-17
CA2529761C (en) 2013-08-13
JP2007521273A (ja) 2007-08-02
NL301177I2 (nl) 2022-08-23
DK1638938T3 (en) 2017-07-31
JP2011252019A (ja) 2011-12-15
NL301177I1 (nl) 2022-06-08
EP1638938A2 (en) 2006-03-29
AU2004249250A1 (en) 2004-12-29
PL1638938T3 (pl) 2017-10-31
ES2632313T3 (es) 2017-09-12
AU2004249250C1 (en) 2012-04-12
CA2529761A1 (en) 2004-12-29
JP5657489B2 (ja) 2015-01-21
WO2004112718A3 (en) 2005-04-07
EP1638938B1 (en) 2017-04-12
FR22C1022I1 (fr) 2022-07-22

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