BE855992A - Inhibiteurs de testoterone 5 alpha-reductase, leur preparation et leur utilisation - Google Patents

Inhibiteurs de testoterone 5 alpha-reductase, leur preparation et leur utilisation

Info

Publication number
BE855992A
BE855992A BE178682A BE178682A BE855992A BE 855992 A BE855992 A BE 855992A BE 178682 A BE178682 A BE 178682A BE 178682 A BE178682 A BE 178682A BE 855992 A BE855992 A BE 855992A
Authority
BE
Belgium
Prior art keywords
testoterone
alpha
preparation
reductase inhibitors
reductase
Prior art date
Application number
BE178682A
Other languages
English (en)
Original Assignee
Richardson Merrell Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richardson Merrell Inc filed Critical Richardson Merrell Inc
Publication of BE855992A publication Critical patent/BE855992A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J21/005—Ketals
    • C07J21/006—Ketals at position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0055—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives
    • C07J41/0061—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives one of the carbon atoms being part of an amide group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C07J9/005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane containing a carboxylic function directly attached or attached by a chain containing only carbon atoms to the cyclopenta[a]hydrophenanthrene skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BE178682A 1976-06-23 1977-06-22 Inhibiteurs de testoterone 5 alpha-reductase, leur preparation et leur utilisation BE855992A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/698,824 US4088760A (en) 1976-06-23 1976-06-23 Testosterone 5α-reductase inhibitors

Publications (1)

Publication Number Publication Date
BE855992A true BE855992A (fr) 1977-10-17

Family

ID=24806807

Family Applications (1)

Application Number Title Priority Date Filing Date
BE178682A BE855992A (fr) 1976-06-23 1977-06-22 Inhibiteurs de testoterone 5 alpha-reductase, leur preparation et leur utilisation

Country Status (4)

Country Link
US (1) US4088760A (fr)
BE (1) BE855992A (fr)
PH (1) PH15306A (fr)
ZA (1) ZA772084B (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5494914A (en) * 1992-05-21 1996-02-27 Endorecherche Inhibitors for testosterone 5α-reductase activity

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1088094B (it) * 1976-10-14 1985-06-04 Hoffmann La Roche Derivati del pregnano
US4191759A (en) * 1978-04-13 1980-03-04 Merck & Co., Inc. N-substituted-17β-carbamoylandrost-4-en-3-one 5α reductase inhibitors
CA1154008A (fr) * 1979-05-02 1983-09-20 Thomas R. Blohm INHIBITEURS DE STEROIDE 5.alpha.-REDUCTASE
US4255345A (en) * 1980-02-19 1981-03-10 Henkel Corporation Steroid production
AT368759B (de) * 1980-05-12 1982-11-10 Henkel Kgaa Verfahren zur herstellung von neuen steroid-20carbons[ureverbindungen
US4814324A (en) * 1987-03-06 1989-03-21 Merck & Co., Inc. Sterol inhibitors of testosterone 5α-reductase
US4910226A (en) * 1987-04-29 1990-03-20 Smithkline Beckman Corporation Steroid 5-alpha-reductase inhibitors
US4981677A (en) * 1987-09-23 1991-01-01 L'oreal Petrolatum-containing aerosol foam concentrate
US5116606A (en) * 1989-03-09 1992-05-26 Alt John P Skin treatment method and solution
JP3029907B2 (ja) * 1991-12-20 2000-04-10 理化学研究所 抗肥満剤
US5264427A (en) * 1992-01-29 1993-11-23 Research Corporation Technologies, Inc. 20-substituted pregnene derivatives and their use as androgen synthesis inhibitors
IT1270853B (it) * 1993-05-20 1997-05-13 Sanofi Elf Procedimento per la preparazione di derivati taurocolanici
US6352724B1 (en) * 1995-03-13 2002-03-05 Lesli A. Taylor Method for treating acne and/or rosacea
US5661141A (en) * 1995-03-27 1997-08-26 Petrow; Vladimir 19-oxygenated steroids as therapeutic agents

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3153615A (en) * 1962-11-06 1964-10-20 Merck & Co Inc Methods of reducing plasma cholesterol
DE1493169A1 (de) * 1965-09-03 1969-06-04 Schering Ag Verfahren zur Herstellung von 5 beta-Bisnorcholanderivaten
DE1643004A1 (de) * 1967-02-07 1971-04-08 Schering Ag Bisnorcholenderivate und Verfahren zu ihrer Herstellung
US3560558A (en) * 1968-10-30 1971-02-02 Shionogi & Co Hexahydroindane dicarboxylic acid derivatives
US3917829A (en) * 1971-11-08 1975-11-04 Research Corp Novel methods of inhibiting the activity of testosterone 5{60 -reductase

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5494914A (en) * 1992-05-21 1996-02-27 Endorecherche Inhibitors for testosterone 5α-reductase activity

Also Published As

Publication number Publication date
PH15306A (en) 1982-11-12
ZA772084B (en) 1978-06-28
US4088760A (en) 1978-05-09

Similar Documents

Publication Publication Date Title
BE884300A (fr) Amides, leur preparation et leur utilisation
BE879586A (fr) Phosphinylalcanoyl prolines, leur preparation et leur utilisation
BE870666A (fr) Compositions catalytiques, leur preparation et leur utilisation
BE870665A (fr) Nouvelles compositions catalytiques, leur preparation et leur utilisation
BE860972A (fr) 0-aryl n-phosphonomethylglycinonitriles et leur utilisation comme herbicides
BE882601A (fr) Mercaptoacyldipeptides, leur preparation et leur utilisation
BE852283A (fr) Compositions carcinostatiques et leur utilisation
BE860606A (fr) Alliages de nickel-mischmetal-calcium et leur utilisation
BE855992A (fr) Inhibiteurs de testoterone 5 alpha-reductase, leur preparation et leur utilisation
BE839255A (fr) Piperazinylimino rifamycines, leur preparation et leur utilisation
BE876040A (fr) Nouvelles piperazines substituees, leur preparation et leur utilisation
BE871807A (fr) 4-quinolyl-guanidines, leur preparation et leur utilisation
BE887323A (fr) 17alpha-acyloxy-5 beta-corticoides et 17alpha-acyloxy-5alpha-corticoides, leur preparation et leur utilisation
BE838833A (fr) Composes 3-acyloxymethyl-cephemes, leur preparation et leur utilisation
BE885117A (fr) 3-amino-oxazolidin-2-ones, leur preparation et leur utilisation
BE882010A (fr) Tetrahydrobenzothiazolylimidazolidinones et leur utilisation
BE859221A (fr) Bis-carbamoylsulfures n-substitues et leur preparation
BE839256A (fr) Piperazinylimino rifamycines, leur preparation et leur utilisation
BE861694A (fr) 3-carboxy-4-oxo-1,4-dihydro-1,8-naphtyridines et leur preparation
BE868953A (fr) Peptides, leur preparation et leur utilisation
BE894056A (fr) 2-oxo-azetidines, leur preparation et leur utilisation
BE825039A (fr) Leuco-colorants d'indolyl-methylene, leur preparation et leur utilisation
BE866728A (fr) 1,2,4-triazoles, leur preparation et leur utilisation
BE891585A (fr) 5 alpha-androstane-17 beta-carboxylates et 5 beta-androstane-17 beta-carboxylates, leur preparation et leur utilisation
BE854237A (fr) 1,2,3-thiadiazol-5-yl-urees, leur procede de preparation et leur utilisation