BE872266A - 15-epi-9-deoxy-6,9 alpha-epoxy-delta 5-pgf1 alpha(prostacycline ou pgi2) - Google Patents

15-epi-9-deoxy-6,9 alpha-epoxy-delta 5-pgf1 alpha(prostacycline ou pgi2)

Info

Publication number: BE872266A
Authority: BE; Belgium
Prior art keywords: alpha; prostacycline; pgi2; epi; deoxy
Prior art date: 1977-11-25

Application number

BE191926A

Other languages

English (en)

Original Assignee

Erba Carlo Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1977-11-25

Filing date

1978-11-24

Publication date

1979-03-16

1978-11-24 Application filed by Erba Carlo Spa filed Critical Erba Carlo Spa

1979-03-16 Publication of BE872266A publication Critical patent/BE872266A/fr

Links

101000862089 Clarkia lewisii Glucose-6-phosphate isomerase, cytosolic 1A Proteins 0.000 title 1
KAQKFAOMNZTLHT-VVUHWYTRSA-N epoprostenol Chemical compound O1C(=CCCCC(O)=O)C[C@@H]2[C@@H](/C=C/[C@@H](O)CCCCC)[C@H](O)C[C@@H]21 KAQKFAOMNZTLHT-VVUHWYTRSA-N 0.000 title 1
KAQKFAOMNZTLHT-OZUDYXHBSA-N prostaglandin I2 Chemical compound O1\C(=C/CCCC(O)=O)C[C@@H]2[C@@H](/C=C/[C@@H](O)CCCCC)[C@H](O)C[C@@H]21 KAQKFAOMNZTLHT-OZUDYXHBSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
- C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/04—Drugs for genital or sexual disorders; Contraceptives for inducing labour or abortion; Uterotonics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
- C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
- C07D307/937—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/94—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Diabetes (AREA)
Hematology (AREA)
Pregnancy & Childbirth (AREA)
Gynecology & Obstetrics (AREA)
Obesity (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Furan Compounds (AREA)
Pyrane Compounds (AREA)

BE191926A 1977-11-25 1978-11-24 15-epi-9-deoxy-6,9 alpha-epoxy-delta 5-pgf1 alpha(prostacycline ou pgi2) BE872266A (fr)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
IT30029/77A IT1088036B (it)	1977-11-25	1977-11-25	15-epi-prostaciclina e prostaciclina analoghi

Publications (1)

Publication Number	Publication Date
BE872266A true BE872266A (fr)	1979-03-16

Family

ID=11228900

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BE191926A BE872266A (fr)	1977-11-25	1978-11-24	15-epi-9-deoxy-6,9 alpha-epoxy-delta 5-pgf1 alpha(prostacycline ou pgi2)

Country Status (13)

Country	Link
US (2)	US4285966A (fr)
JP (1)	JPS5481259A (fr)
BE (1)	BE872266A (fr)
CA (1)	CA1198416A (fr)
CH (1)	CH643838A5 (fr)
DE (1)	DE2850885A1 (fr)
FR (1)	FR2409996B1 (fr)
GB (1)	GB2008581B (fr)
HU (1)	HU181425B (fr)
IT (1)	IT1088036B (fr)
NL (1)	NL7811572A (fr)
SE (1)	SE444437B (fr)
ZA (1)	ZA786234B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1098350B (it) *	1977-07-28	1985-09-07	Upjohn Co	Derivati prostaglandinici
DE2902809A1 (de) *	1979-01-25	1980-08-07	Hoechst Ag	Neue analoga von prostacyclin
DE3029984C2 (de)	1980-08-08	1983-12-15	Grünenthal GmbH, 5190 Stolberg	2-Oxabicyclo [3.3.0] octanderivate und diese enthaltende Arzneimittel
US4401824A (en) *	1982-03-08	1983-08-30	The Upjohn Company	Benzopyran compounds, derivatives of prostaglandins
JPS60172941A (ja) *	1984-02-16	1985-09-06	Sankyo Co Ltd	カルバサイクリン類
JPS60181041A (ja) *	1984-02-29	1985-09-14	Sankyo Co Ltd	カルバサイクリン誘導体
US4616034A (en) *	1985-02-28	1986-10-07	G. D. Searle & Co.	15(R)-5-fluoroprostacyclins, pharmaceutical compositions and anti-thrombotic method of use thereof
HU197733B (en) *	1985-05-29	1989-05-29	Chinoin Gyogyszer Es Vegyeszet	Process for producing ephedrin-salts of 7-oxo-prosta-cyclin derivatives

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL51189A (en)	1976-02-04	1985-08-30	Upjohn Co	Prostaglandin analogs
US4158667A (en) *	1976-02-04	1979-06-19	The Upjohn Company	6-Keto PGF analogs
GB1583961A (en)	1976-05-11	1981-02-04	Wellcome Found	Prostacyclin and derivatives thereof
US4123441A (en) *	1976-09-22	1978-10-31	The Upjohn Company	Enlarged-hetero-ring prostacyclin analogs
US4124601A (en) *	1976-12-30	1978-11-07	The Upjohn Company	Certain 5-halo-6,9α-epoxy-14-bromo(or chloro)-PGF1 compounds
AU524786B2 (en)	1977-03-07	1982-10-07	The Upjohn Company	Prostacyclins
ZA782614B (en)	1977-06-06	1979-04-25	Univ Chicago	Novel prostacyclin analogs and chemical synthesis

1977
- 1977-11-25 IT IT30029/77A patent/IT1088036B/it active
1978
- 1978-10-30 US US05/955,631 patent/US4285966A/en not_active Expired - Lifetime
- 1978-11-06 ZA ZA00786234A patent/ZA786234B/xx unknown
- 1978-11-10 GB GB7844139A patent/GB2008581B/en not_active Expired
- 1978-11-24 BE BE191926A patent/BE872266A/fr not_active IP Right Cessation
- 1978-11-24 SE SE7812124A patent/SE444437B/sv unknown
- 1978-11-24 HU HU78EA187A patent/HU181425B/hu unknown
- 1978-11-24 CA CA000316849A patent/CA1198416A/fr not_active Expired
- 1978-11-24 DE DE19782850885 patent/DE2850885A1/de not_active Withdrawn
- 1978-11-24 NL NL7811572A patent/NL7811572A/xx not_active Application Discontinuation
- 1978-11-24 FR FR787833311A patent/FR2409996B1/fr not_active Expired
- 1978-11-24 CH CH1207278A patent/CH643838A5/de not_active IP Right Cessation
- 1978-11-25 JP JP14498778A patent/JPS5481259A/ja active Pending
1980
- 1980-04-18 US US06/141,341 patent/US4321205A/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
JPS5481259A (en)	1979-06-28
CA1198416A (fr)	1985-12-24
SE444437B (sv)	1986-04-14
ZA786234B (en)	1979-10-31
CH643838A5 (de)	1984-06-29
FR2409996B1 (fr)	1985-07-26
US4285966A (en)	1981-08-25
NL7811572A (nl)	1979-05-29
US4321205A (en)	1982-03-23
FR2409996A1 (fr)	1979-06-22
GB2008581B (en)	1982-06-30
SE7812124L (sv)	1979-05-26
GB2008581A (en)	1979-06-06
DE2850885A1 (de)	1979-05-31
IT1088036B (it)	1985-06-04
HU181425B (en)	1983-07-28

Legal Events

Date

Code

Title

Description

1987-05-31

RE

Patent lapsed

Owner name: CARLO ERBA S.P.A.

Effective date: 19861130

Publication	Publication Date	Title
NO772943L (no)	1979-02-27	Arbeidsstol.
IT7825232A0 (it)	1978-06-30	Struttura d'angolo.
BE868868A (fr)	1979-01-10	1-thienyl- et furyl-2,3,4,5-tetrahydro-1h-3-benzazepines substituees
NL180032B (nl)	1986-07-16	Stootkussen.
FI773012A7 (fi)	1978-08-25	Foerfarande foer framstaellning av 1,4:3,6-dianhydro-d-glucitol-2-nitrat
TR19604A (tr)	1979-09-01	2,6-dinitroanilin herbisid terkipler
NL7801421A (nl)	1978-09-27	Preparaten.
NO780846L (no)	1978-09-12	Dentinstift.
FI781480A7 (fi)	1978-11-11	Foerfarande foer framstaellning av 5(6)-tiobensimidazolderivat.
FI781962A7 (fi)	1978-12-22	Foerfarande foer framstaellning av 7,8-dihydro-14-hydroxinormorfin
FI783181A7 (fi)	1979-04-22	Framstaellning av 2,6-diaminonebulariner
IT7925612A0 (it)	1979-09-11	Agenti antipertensivi.
IT7830089A0 (it)	1978-11-23	Impianto d'ascensore.
NL7811593A (nl)	1979-05-29	Cooerdinaatuitleesinrichting.
NL7803720A (nl)	1978-10-10	(1,5)pyrido2,3-bbenzothiazepine-derivaten.
BE873054A (fr)	1979-06-22	N,n'-digesubstitueerd cyclisch diamine, alsmede werkwijze ter bereiding daarvan
NL180447C (nl)	1987-02-16	Stootkussen.
IT7831369A0 (it)	1978-12-28	Ancora.
NL7804361A (nl)	1978-10-27	Leucinerijk 3,1-s-alpha2-glycoproteine, zijn berei- ding en toepassing.
PT67637B (pt)	1979-09-20	(2-thio)urees 1,3-disubstituees
NL7805752A (nl)	1978-11-28	Niet-klemmende zuiger.
FI781339A7 (fi)	1978-11-07	Nya 3,5-disubstituerade 1h-1,2,4-triazoler
NL7807020A (nl)	1979-02-20	Hydrosol.
IT1088966B (it)	1985-06-10	13,14-dideidro-prostaglandine
FI772488A7 (fi)	1978-11-05	Foerfarande foer framstaellning av 2,9-dioxatricyklo(4,3,1,03,7)-dekaner