BE878662A - Nouveau & -aryl &,&-bis (w-(amino disubstitue) alkyl) acetamides et composes apparentes utiles comme medicaments anti-arythmiques et leur procede de preparation - Google Patents

Nouveau & -aryl &,&-bis (w-(amino disubstitue) alkyl) acetamides et composes apparentes utiles comme medicaments anti-arythmiques et leur procede de preparation

Info

Publication number
BE878662A
BE878662A BE0/197051A BE197051A BE878662A BE 878662 A BE878662 A BE 878662A BE 0/197051 A BE0/197051 A BE 0/197051A BE 197051 A BE197051 A BE 197051A BE 878662 A BE878662 A BE 878662A
Authority
BE
Belgium
Prior art keywords
disubstitue
acetamides
aryl
bis
amino
Prior art date
Application number
BE0/197051A
Other languages
English (en)
Inventor
P Yonan
Original Assignee
Searle & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Searle & Co filed Critical Searle & Co
Publication of BE878662A publication Critical patent/BE878662A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
BE0/197051A 1978-09-08 1979-09-07 Nouveau & -aryl &,&-bis (w-(amino disubstitue) alkyl) acetamides et composes apparentes utiles comme medicaments anti-arythmiques et leur procede de preparation BE878662A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/940,527 US4217306A (en) 1978-05-01 1978-09-08 α-Aryl-α,α-bis[ω-(disubstituted amino)alkyl]-acetamides

Publications (1)

Publication Number Publication Date
BE878662A true BE878662A (fr) 1980-03-07

Family

ID=25474978

Family Applications (1)

Application Number Title Priority Date Filing Date
BE0/197051A BE878662A (fr) 1978-09-08 1979-09-07 Nouveau & -aryl &,&-bis (w-(amino disubstitue) alkyl) acetamides et composes apparentes utiles comme medicaments anti-arythmiques et leur procede de preparation

Country Status (20)

Country Link
US (1) US4217306A (fr)
JP (1) JPS5592350A (fr)
AT (3) AT364813B (fr)
AU (1) AU5068679A (fr)
BE (1) BE878662A (fr)
CA (1) CA1136622A (fr)
DE (1) DE2936287A1 (fr)
DK (1) DK374879A (fr)
ES (1) ES483985A1 (fr)
FR (1) FR2435462A1 (fr)
GB (1) GB2030984B (fr)
GR (1) GR72494B (fr)
IL (1) IL58200A (fr)
IT (1) IT1120561B (fr)
NL (1) NL7906745A (fr)
NO (1) NO792901L (fr)
NZ (1) NZ191505A (fr)
PT (1) PT70151B (fr)
SE (1) SE7907432L (fr)
ZA (1) ZA794764B (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5097035A (en) * 1984-07-09 1992-03-17 G. D. Searle & Co. Monobasic disobutamide derivatives
US4639524A (en) * 1984-07-09 1987-01-27 G. D. Searle & Co. Monobasic disobutamide derivatives
US4791199A (en) * 1985-09-19 1988-12-13 G. D. Searle & Co. Process for antiarrhythmic 1,3-diazabicyclo[4.4.0]dec-2-en-4-ones
EP0370712A3 (fr) * 1988-11-18 1991-10-02 Ajinomoto Co., Inc. Dérivés de l'éthylamine et médicaments hypotenseurs les contenant
FR2686339B1 (fr) * 1992-01-22 1994-03-11 Adir Cie Nouveaux amides et sulfonamides naphtaleniques, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent.
US5432284A (en) * 1993-09-08 1995-07-11 G. D. Searle & Co. Process for the preparation of heterocyclic alkylamide derivatives

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2884436A (en) * 1954-08-28 1959-04-28 Nl Combinatie Chem Ind Parasympathicolytically active alpha, alpha-diphenyl-gamma-dialkylaminobutyramide compounds and manufacture thereof
US3022314A (en) * 1955-06-20 1962-02-20 Upjohn Co Alpha-phenyl-omega-amino-alkanamides
US3022302A (en) * 1956-03-15 1962-02-20 Pharmacia Ab Manufacture of nu, nu-disubstituted amides of aryl acetic acids
US3078275A (en) * 1956-05-28 1963-02-19 Upjohn Co N, n-disubstituted-alpha-(tertiaryaminoalkyl)-alpha, alpha-diphenylacetamides
US2894955A (en) * 1956-11-19 1959-07-14 Upjohn Co Organic compounds
US3225091A (en) * 1962-02-01 1965-12-21 Lilly Co Eli Anticholinergic substituted butyramides
NL124729C (fr) * 1963-05-14
BE689347A (fr) 1965-12-09 1967-04-14 Madan Ag
BE673495A (fr) 1965-12-09 1966-04-01 Madan Ag Amides et N-hydroxyamides dérivés d'acides para-alkyloxyarylacétiques substitués et leur préparation
US4107205A (en) * 1977-03-11 1978-08-15 G. D. Searle & Co. α-Aryl-α,α-bis[ω-(disubstituted amino)alkyl]acetamides and related compounds

Also Published As

Publication number Publication date
ATA600180A (de) 1982-07-15
PT70151B (pt) 1981-12-11
ATA600280A (de) 1982-07-15
ATA592679A (de) 1981-04-15
NO792901L (no) 1980-03-11
GB2030984B (en) 1983-07-27
ES483985A1 (es) 1980-04-16
IL58200A0 (en) 1979-12-30
AT370088B (de) 1983-02-25
FR2435462A1 (fr) 1980-04-04
JPS5592350A (en) 1980-07-12
NL7906745A (nl) 1980-03-11
CA1136622A (fr) 1982-11-30
DE2936287A1 (de) 1980-03-20
AT364813B (de) 1981-11-25
AT370087B (de) 1983-02-25
AU5068679A (en) 1980-03-27
GR72494B (fr) 1983-11-15
IT1120561B (it) 1986-03-26
SE7907432L (sv) 1980-03-09
NZ191505A (en) 1982-03-30
GB2030984A (en) 1980-04-16
DK374879A (da) 1980-03-09
PT70151A (en) 1979-09-01
IT7950202A0 (it) 1979-09-07
IL58200A (en) 1982-12-31
US4217306A (en) 1980-08-12
ZA794764B (en) 1981-04-29

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