IT7950202A0 - Derivati alfa-aril-alfa alfa-bisomega-ammino bisostituiti alchilacetammidici ditati di proprieta'farmacologiche antiaritmia - Google Patents

Derivati alfa-aril-alfa alfa-bisomega-ammino bisostituiti alchilacetammidici ditati di proprieta'farmacologiche antiaritmia

Info

Publication number
IT7950202A0
IT7950202A0 IT7950202A IT5020279A IT7950202A0 IT 7950202 A0 IT7950202 A0 IT 7950202A0 IT 7950202 A IT7950202 A IT 7950202A IT 5020279 A IT5020279 A IT 5020279A IT 7950202 A0 IT7950202 A0 IT 7950202A0
Authority
IT
Italy
Prior art keywords
aril
alfa
alpha derivatives
alpha
derivatives
Prior art date
Application number
IT7950202A
Other languages
English (en)
Other versions
IT1120561B (it
Inventor
Peter K Yonan
Original Assignee
Skokie Illinois U S A G D Sear
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Skokie Illinois U S A G D Sear filed Critical Skokie Illinois U S A G D Sear
Publication of IT7950202A0 publication Critical patent/IT7950202A0/it
Application granted granted Critical
Publication of IT1120561B publication Critical patent/IT1120561B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IT50202/79A 1978-09-08 1979-09-07 Derivati alfa-aril-alfa alfa-bis omega-ammino bisostituiti alchilacetammidici ditati di proprieta' farmacologiche antiaritmia IT1120561B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/940,527 US4217306A (en) 1978-05-01 1978-09-08 α-Aryl-α,α-bis[ω-(disubstituted amino)alkyl]-acetamides

Publications (2)

Publication Number Publication Date
IT7950202A0 true IT7950202A0 (it) 1979-09-07
IT1120561B IT1120561B (it) 1986-03-26

Family

ID=25474978

Family Applications (1)

Application Number Title Priority Date Filing Date
IT50202/79A IT1120561B (it) 1978-09-08 1979-09-07 Derivati alfa-aril-alfa alfa-bis omega-ammino bisostituiti alchilacetammidici ditati di proprieta' farmacologiche antiaritmia

Country Status (20)

Country Link
US (1) US4217306A (it)
JP (1) JPS5592350A (it)
AT (3) AT364813B (it)
AU (1) AU5068679A (it)
BE (1) BE878662A (it)
CA (1) CA1136622A (it)
DE (1) DE2936287A1 (it)
DK (1) DK374879A (it)
ES (1) ES483985A1 (it)
FR (1) FR2435462A1 (it)
GB (1) GB2030984B (it)
GR (1) GR72494B (it)
IL (1) IL58200A (it)
IT (1) IT1120561B (it)
NL (1) NL7906745A (it)
NO (1) NO792901L (it)
NZ (1) NZ191505A (it)
PT (1) PT70151B (it)
SE (1) SE7907432L (it)
ZA (1) ZA794764B (it)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4639524A (en) * 1984-07-09 1987-01-27 G. D. Searle & Co. Monobasic disobutamide derivatives
US5097035A (en) * 1984-07-09 1992-03-17 G. D. Searle & Co. Monobasic disobutamide derivatives
US4791199A (en) * 1985-09-19 1988-12-13 G. D. Searle & Co. Process for antiarrhythmic 1,3-diazabicyclo[4.4.0]dec-2-en-4-ones
EP0370712A3 (en) * 1988-11-18 1991-10-02 Ajinomoto Co., Inc. Ethylamine derivatives and hypotensives containing the same
FR2686339B1 (fr) * 1992-01-22 1994-03-11 Adir Cie Nouveaux amides et sulfonamides naphtaleniques, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent.
US5432284A (en) * 1993-09-08 1995-07-11 G. D. Searle & Co. Process for the preparation of heterocyclic alkylamide derivatives

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2884436A (en) * 1954-08-28 1959-04-28 Nl Combinatie Chem Ind Parasympathicolytically active alpha, alpha-diphenyl-gamma-dialkylaminobutyramide compounds and manufacture thereof
US3022314A (en) * 1955-06-20 1962-02-20 Upjohn Co Alpha-phenyl-omega-amino-alkanamides
US3022302A (en) * 1956-03-15 1962-02-20 Pharmacia Ab Manufacture of nu, nu-disubstituted amides of aryl acetic acids
US3078275A (en) * 1956-05-28 1963-02-19 Upjohn Co N, n-disubstituted-alpha-(tertiaryaminoalkyl)-alpha, alpha-diphenylacetamides
US2894955A (en) * 1956-11-19 1959-07-14 Upjohn Co Organic compounds
US3225091A (en) * 1962-02-01 1965-12-21 Lilly Co Eli Anticholinergic substituted butyramides
NL124729C (it) * 1963-05-14
BE673495A (fr) 1965-12-09 1966-04-01 Madan Ag Amides et N-hydroxyamides dérivés d'acides para-alkyloxyarylacétiques substitués et leur préparation
BE689347A (it) 1965-12-09 1967-04-14 Madan Ag
US4107205A (en) * 1977-03-11 1978-08-15 G. D. Searle & Co. α-Aryl-α,α-bis[ω-(disubstituted amino)alkyl]acetamides and related compounds

Also Published As

Publication number Publication date
ATA600180A (de) 1982-07-15
PT70151A (en) 1979-09-01
AT370088B (de) 1983-02-25
AT364813B (de) 1981-11-25
PT70151B (pt) 1981-12-11
DK374879A (da) 1980-03-09
SE7907432L (sv) 1980-03-09
IL58200A (en) 1982-12-31
BE878662A (fr) 1980-03-07
IL58200A0 (en) 1979-12-30
GR72494B (it) 1983-11-15
CA1136622A (en) 1982-11-30
NZ191505A (en) 1982-03-30
ATA600280A (de) 1982-07-15
JPS5592350A (en) 1980-07-12
FR2435462A1 (fr) 1980-04-04
AT370087B (de) 1983-02-25
ATA592679A (de) 1981-04-15
AU5068679A (en) 1980-03-27
GB2030984A (en) 1980-04-16
ES483985A1 (es) 1980-04-16
DE2936287A1 (de) 1980-03-20
NL7906745A (nl) 1980-03-11
NO792901L (no) 1980-03-11
ZA794764B (en) 1981-04-29
IT1120561B (it) 1986-03-26
US4217306A (en) 1980-08-12
GB2030984B (en) 1983-07-27

Similar Documents

Publication Publication Date Title
IT1192347B (it) Derivati di alchilendiamine
SE7907493L (sv) Anilinokinazolinderivat
SE7900380L (sv) Anisamidderivat
FI791081A7 (fi) Tioetiansyraderivat
FI790486A7 (fi) Aminosocker-derivat
FR2517303B1 (fr) Derives d'imidazole
BE875773A (nl) 2'deoxy-5-(halogeenvinyl)-uridines
IT1140976B (it) Derivati di alchil-chetoesopiranosidi
ATE202T1 (de) 2-cycloalkyl-pyrimidin(5)
IT1127231B (it) Derivati spiro-policiclicimidazolidinadionici
IT1209143B (it) Derivati di 7-osso-4-tia-1-aza-biciclo-[3,2,0]eptano
FI792769A7 (fi) 3,4,5-trihydroxipiperidinderivat
IT1122489B (it) Derivati di cloroambucile
IT1110540B (it) Derivati di alcanolammine
LU81071A1 (fr) Vitrai 12
IT1188839B (it) Derivati di arabino-furanosil-citosina
IT1122180B (it) Derivati di 1-fenil-1-propanolo
IT7950202A0 (it) Derivati alfa-aril-alfa alfa-bisomega-ammino bisostituiti alchilacetammidici ditati di proprieta'farmacologiche antiaritmia
DK143979A (da) Chromanonderivater
BE874488A (fr) Derives benzylideniques
IT1116869B (it) Derivati di n-alcheni-moranolina aventi attivita'farmacologica
FI790141A7 (fi) 2 6-dinitrobensenaminer
IT1162702B (it) Derivati di 11-alcanoil-4"-isonitril-oleandomicina
DK149809C (da) 1-alkylsubstituerede pyrazolderivater
IT1115134B (it) Derivati di fenilpirolo