BE897883A - Acide azetidinyl sulfonique et analogues a action therapeutique - Google Patents

Acide azetidinyl sulfonique et analogues a action therapeutique

Info

Publication number
BE897883A
BE897883A BE0/211621A BE211621A BE897883A BE 897883 A BE897883 A BE 897883A BE 0/211621 A BE0/211621 A BE 0/211621A BE 211621 A BE211621 A BE 211621A BE 897883 A BE897883 A BE 897883A
Authority
BE
Belgium
Prior art keywords
analogs
sulfonic acid
therapeutic action
hydrogen atom
azetidinyl
Prior art date
Application number
BE0/211621A
Other languages
English (en)
Inventor
W A Slusarchyk
D R Kronenthal
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Publication of BE897883A publication Critical patent/BE897883A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/085—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a nitrogen atom directly attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Beta-lactames portant un substituant (R5,R6,O, C SO3H) en position 1 et un substituant acylamine en position 3. Ils répondant à la formule (I), dans laquelle R1 est un radical acyle, un atome d'hydrogène ou un groupement protecteur de la fonction amine, R2 est un atome d'hydrogène ou un radical méthoxy, R3, R4, R5, et R6 sont identiques ou différents et sont chacun, de préférence, un atome d'hydrogène ou un radical alkyle inférieur. Ces composés sont utilisables comme agents antibactériens.
BE0/211621A 1982-10-06 1983-09-30 Acide azetidinyl sulfonique et analogues a action therapeutique BE897883A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US43317582A 1982-10-06 1982-10-06

Publications (1)

Publication Number Publication Date
BE897883A true BE897883A (fr) 1984-03-30

Family

ID=23719123

Family Applications (1)

Application Number Title Priority Date Filing Date
BE0/211621A BE897883A (fr) 1982-10-06 1983-09-30 Acide azetidinyl sulfonique et analogues a action therapeutique

Country Status (27)

Country Link
JP (1) JPS5988462A (fr)
KR (1) KR900005132B1 (fr)
AU (1) AU568312B2 (fr)
BE (1) BE897883A (fr)
CA (1) CA1253501A (fr)
CH (1) CH658858A5 (fr)
DD (1) DD222016A5 (fr)
DE (1) DE3336262A1 (fr)
DK (1) DK457983A (fr)
ES (1) ES8504814A1 (fr)
FI (1) FI833631A7 (fr)
FR (1) FR2534253B1 (fr)
GB (1) GB2129428B (fr)
GR (1) GR79704B (fr)
HU (1) HU190507B (fr)
IE (1) IE56600B1 (fr)
IL (1) IL69917A (fr)
IT (1) IT1171722B (fr)
LU (1) LU85033A1 (fr)
NL (1) NL8303410A (fr)
NO (1) NO833626L (fr)
NZ (1) NZ205642A (fr)
PH (1) PH24175A (fr)
PT (1) PT77458B (fr)
SE (1) SE8305509L (fr)
SU (1) SU1318146A3 (fr)
ZA (1) ZA837491B (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1985004876A1 (fr) * 1984-04-24 1985-11-07 Takeda Chemical Industries, Ltd. Derives de 2-azetidinone et leur procede de preparation
EP0135194A1 (fr) * 1983-09-16 1985-03-27 Takeda Chemical Industries, Ltd. Azétidinones et leur préparation
US4581170A (en) * 1984-08-03 1986-04-08 E. R. Squibb & Sons, Inc. N-hydroxyl protecting groups and process and intermediates for the preparation of 3-acylamino-1-hydroxy-2-azetidinones
EP0171064B1 (fr) * 1984-08-06 1995-07-12 Fujisawa Pharmaceutical Co., Ltd. Dérivés de l'azétidinone et procédé pour leur préparation
UY34585A (es) 2012-01-24 2013-09-02 Aicuris Gmbh & Co Kg Compuestos b-lactámicos sustituidos con amidina, su preparación y uso

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4337197A (en) * 1980-10-31 1982-06-29 E. R. Squibb & Sons, Inc. O-sulfated β-lactam hydroxamic acids and intermediates

Also Published As

Publication number Publication date
PT77458B (en) 1986-02-26
CA1253501A (fr) 1989-05-02
KR840006337A (ko) 1984-11-29
FR2534253A1 (fr) 1984-04-13
GB8326626D0 (en) 1983-11-09
NO833626L (no) 1984-04-09
NL8303410A (nl) 1984-05-01
JPS5988462A (ja) 1984-05-22
ES526282A0 (es) 1985-04-16
FI833631A0 (fi) 1983-10-06
GB2129428B (en) 1986-03-19
DK457983D0 (da) 1983-10-04
FR2534253B1 (fr) 1985-07-26
IL69917A (en) 1987-10-20
DK457983A (da) 1984-04-07
PT77458A (en) 1983-11-01
KR900005132B1 (ko) 1990-07-20
AU568312B2 (en) 1987-12-24
IE56600B1 (en) 1991-10-09
LU85033A1 (fr) 1984-05-10
ES8504814A1 (es) 1985-04-16
SU1318146A3 (ru) 1987-06-15
DE3336262A1 (de) 1984-04-12
IE832354L (en) 1984-04-06
ZA837491B (en) 1984-06-27
SE8305509L (sv) 1984-04-07
GR79704B (fr) 1984-10-31
DD222016A5 (de) 1985-05-08
GB2129428A (en) 1984-05-16
CH658858A5 (fr) 1986-12-15
FI833631A7 (fi) 1984-04-07
HU190507B (en) 1986-09-29
IT8323172A0 (it) 1983-10-06
PH24175A (en) 1990-03-22
AU1993983A (en) 1984-04-12
IL69917A0 (en) 1984-01-31
NZ205642A (en) 1986-08-08
IT1171722B (it) 1987-06-10
SE8305509D0 (sv) 1983-10-06

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: E.R. SQUIBB & SONS INC.

Effective date: 19930930