BE900855A - Compositions pour le traitement prophylactique de l'osteite et de l'osteomyelite. - Google Patents

Compositions pour le traitement prophylactique de l'osteite et de l'osteomyelite.

Info

Publication number
BE900855A
BE900855A BE0/213858A BE213858A BE900855A BE 900855 A BE900855 A BE 900855A BE 0/213858 A BE0/213858 A BE 0/213858A BE 213858 A BE213858 A BE 213858A BE 900855 A BE900855 A BE 900855A
Authority
BE
Belgium
Prior art keywords
osteomyelitis
bone
compositions
prophylactic treatment
compounds
Prior art date
Application number
BE0/213858A
Other languages
English (en)
Original Assignee
Geistlich Soehne Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Geistlich Soehne Ag filed Critical Geistlich Soehne Ag
Publication of BE900855A publication Critical patent/BE900855A/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/15—Six-membered rings
    • C07D285/16—Thiadiazines; Hydrogenated thiadiazines
    • C07D285/18—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Saccharide Compounds (AREA)

Abstract

L'invention concerne des composés de la formule (I) dans laquelle R1 et R2 représentent chacun un atome d'hydrogène ou un radical alkyle en C1 à C et R2 peut également représenter un radical de la formule (II) dans laquelle R est tel que défini précédemment , ainsi que les compositions pharmaceutiques qui contiennent ces composés en vue de combattre l'apparition d'une ostéite ou d'une ostéomyélite plus particulièrement chez des patients souffrant de blessures osseuses d'origine traumatique.
BE0/213858A 1983-10-20 1984-10-19 Compositions pour le traitement prophylactique de l'osteite et de l'osteomyelite. BE900855A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB838328073A GB8328073D0 (en) 1983-10-20 1983-10-20 Chemical compounds

Publications (1)

Publication Number Publication Date
BE900855A true BE900855A (fr) 1985-02-15

Family

ID=10550497

Family Applications (1)

Application Number Title Priority Date Filing Date
BE0/213858A BE900855A (fr) 1983-10-20 1984-10-19 Compositions pour le traitement prophylactique de l'osteite et de l'osteomyelite.

Country Status (10)

Country Link
US (1) US4604391A (fr)
EP (1) EP0139534B1 (fr)
JP (1) JPS60105617A (fr)
AT (1) ATE89731T1 (fr)
AU (1) AU3457484A (fr)
BE (1) BE900855A (fr)
CH (1) CH660969A5 (fr)
DE (2) DE3438470A1 (fr)
GB (1) GB8328073D0 (fr)
IT (1) IT1178155B (fr)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3506288A1 (de) * 1984-09-06 1986-03-13 Johannes 7900 Ulm Reinmüller Vorrichtung zum einlegen in wunden und wundhoehlen
GB8424518D0 (en) * 1984-09-28 1984-11-07 Geistlich Sohne Af Fur Chemisc Chemical compounds
GB8827986D0 (en) * 1988-11-30 1989-01-05 Geistlich Soehne Ag Chemical product
US5819748A (en) * 1988-11-30 1998-10-13 Ed Geistlich Sohne Ag Fur Chemische Industrie Implant for use in bone surgery
GB9015108D0 (en) * 1990-07-09 1990-08-29 Geistlich Soehne Ag Chemical compositions
GB9216155D0 (en) * 1992-07-30 1992-09-09 Geistlich Soehne Ag Treatment of dentoalveolar infections
US6488912B1 (en) 1992-07-30 2002-12-03 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Treatment of dentoalveolar infections with taurolidine and/or taurultam
DE19708782C1 (de) * 1997-03-04 1998-08-06 Claus Prof Dr Herdeis Verfahren zur Herstellung von 2-Aminoethansulfonylazid-säureadditionssalzen, 2-Aminoethansulfonylazid-hydrochlorid sowie dessen Verwendung
US6011030A (en) * 1997-09-22 2000-01-04 Ed. Geistlich Sohne Ag Fur Chemische Industrie Method of treating symptoms of microbial infection or sepsis
US5972933A (en) * 1998-01-08 1999-10-26 Ed. Geistlich Sohne Ag Fur Chemische Industrie Method of treating microbial infections
US6166007A (en) 1998-07-02 2000-12-26 Sodemann; Klaus Antimicrobial locks comprising taurinamide derivatives and carboxylic acids and/or salts thereof
US6350742B1 (en) * 1998-09-11 2002-02-26 Carter-Wallace, Inc. Compositions and methods for treating infections of the ear
RU2228526C2 (ru) * 1999-10-12 2004-05-10 Российский научный центр "Восстановительная травматология и ортопедия" им. акад. Г.А.Илизарова Способ оценки результатов лечения больных хроническим остеомиелитом
CA2393159C (fr) * 1999-12-06 2010-04-20 Paul Calabresi Methodes de traitement de tumeurs
CN100519525C (zh) * 1999-12-06 2009-07-29 葛兰素集团有限公司 芳香砜类及其医疗用途
US20020004502A1 (en) * 2000-01-05 2002-01-10 Redmond H. Paul Treatment of inflammatory bowel disease
CA2462564C (fr) 2001-10-01 2012-07-10 Rhode Island Hospital Procede d'inhibition de metastases
US20050008684A1 (en) * 2003-07-10 2005-01-13 Claus Herdeis Method of treatment for acne, rosacea and ulcers with taurolidine and/or taurultam in a pharmaceutical composition
US7696182B2 (en) 2004-11-02 2010-04-13 Nd Partners, Llc Antimicrobial locking solutions comprising taurinamide derivatives and biologically acceptable salts and acids, with the addition of small concentrations of heparin
EP3028705A1 (fr) * 2006-09-07 2016-06-08 Ed. Geistlich Söhne Ag Für Chemische Industrie Traitement du cancer des os
CA3086396A1 (fr) 2017-12-21 2019-06-27 Cormedix Inc. Procedes et compositions pharmaceutiques pour traiter candida auris dans le sang
ES2918000B2 (es) 2022-03-16 2024-03-20 Univ Madrid Complutense Implantes personalizados con actividad antimicrobiana para prevenir y tratar infecciones oseas
US11738120B1 (en) 2022-04-14 2023-08-29 Cormedix Inc. Synthesis of taurolidine, purity profiles and polymorphs

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1124285A (en) * 1964-10-06 1968-08-21 Geistlich Soehne Ag Novel perhydro-1,2,4-thiadiazine dioxides-(1,1), their preparation and compositionscontaining them
GB1557163A (en) * 1975-06-24 1979-12-05 Geistlich Soehne Ag Dental care preparations
GB1525296A (en) * 1975-08-04 1978-09-20 Geistlich Soehne Ag Antibacterial compositions
US4107305A (en) * 1975-08-04 1978-08-15 Ed. Geistlich Sohne A.G. Fur Chemische Industrie Treatment of endotoxaemia
US4337251A (en) * 1979-05-09 1982-06-29 Ed. Geistlich Sohne Ag Fur Chemische Industrie Method of avoiding and removing adhesions

Also Published As

Publication number Publication date
DE3486150T2 (de) 1993-11-04
ATE89731T1 (de) 1993-06-15
AU3457484A (en) 1985-05-09
EP0139534A2 (fr) 1985-05-02
JPS60105617A (ja) 1985-06-11
EP0139534A3 (en) 1985-10-23
DE3438470A1 (de) 1985-05-30
US4604391A (en) 1986-08-05
IT8449032A0 (it) 1984-10-18
EP0139534B1 (fr) 1993-05-26
CH660969A5 (de) 1987-06-30
IT1178155B (it) 1987-09-09
IT8449032A1 (it) 1986-04-18
DE3486150D1 (de) 1993-07-01
GB8328073D0 (en) 1983-11-23

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: ED. GEISTLICH SOHNE A.G. FUR CHEMISCHE INDUSTRIE

Effective date: 19931031