MA24729A1 - Macrolides nouveaux. - Google Patents

Macrolides nouveaux.

Info

Publication number
MA24729A1
MA24729A1 MA25407A MA25407A MA24729A1 MA 24729 A1 MA24729 A1 MA 24729A1 MA 25407 A MA25407 A MA 25407A MA 25407 A MA25407 A MA 25407A MA 24729 A1 MA24729 A1 MA 24729A1
Authority
MA
Morocco
Prior art keywords
compounds
new macrolides
macrolides
new
infections
Prior art date
Application number
MA25407A
Other languages
English (en)
Inventor
Philip Dirlam John
Alastair Irvine Hamish
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of MA24729A1 publication Critical patent/MA24729A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

L'INVENTION CONCERNE DES COMPOSÉS DE FORMULE DANS LAQUELLE R1, R2, R3, R4 ET Y REPRÉSENTENT DIVERS RADICAUX. ELLE CONCERNE ÉGALEMENT UN PROCÉDÉ POUR LEUR PRÉPARATION AINSI QUE DES COMPOSITIONS PHARMACEUTIQUES LES CONTENANT. APPLICATION : UTILISATION DE CES COMPOSÉS ET COMPOSITIONS DANS LE TRAITEMENT DE DIVERSES INFECTIONS BACTÉRIENNES ET INFECTIONS PAR DES PROTOZOAIRES.
MA25407A 1998-01-02 1998-12-30 Macrolides nouveaux. MA24729A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US7034398P 1998-01-02 1998-01-02

Publications (1)

Publication Number Publication Date
MA24729A1 true MA24729A1 (fr) 1999-07-01

Family

ID=22094723

Family Applications (1)

Application Number Title Priority Date Filing Date
MA25407A MA24729A1 (fr) 1998-01-02 1998-12-30 Macrolides nouveaux.

Country Status (34)

Country Link
US (2) US6472371B1 (fr)
EP (1) EP1044207A1 (fr)
JP (1) JP2002500230A (fr)
KR (1) KR100352809B1 (fr)
CN (1) CN1284081A (fr)
AP (1) AP9801420A0 (fr)
AR (4) AR014948A1 (fr)
AU (1) AU756409B2 (fr)
BG (1) BG104644A (fr)
BR (1) BR9814601A (fr)
CA (1) CA2316919C (fr)
CO (1) CO4970821A1 (fr)
CZ (1) CZ20002458A3 (fr)
DZ (1) DZ2698A1 (fr)
EA (1) EA200000594A1 (fr)
GT (1) GT199800206A (fr)
HR (1) HRP20000442A2 (fr)
HU (1) HUP0100420A3 (fr)
IL (1) IL137024A0 (fr)
IS (1) IS5528A (fr)
MA (1) MA24729A1 (fr)
NO (1) NO20003347L (fr)
NZ (1) NZ504986A (fr)
OA (1) OA11438A (fr)
PA (1) PA8465301A1 (fr)
PE (1) PE20000049A1 (fr)
PL (1) PL341642A1 (fr)
SK (1) SK9782000A3 (fr)
TN (1) TNSN98238A1 (fr)
TW (1) TW520374B (fr)
UY (2) UY25330A1 (fr)
WO (1) WO1999035156A1 (fr)
YU (1) YU41500A (fr)
ZA (1) ZA9811939B (fr)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AP9801420A0 (en) 1998-01-02 1998-12-31 Pfizer Prod Inc Novel macrolides.
AP1060A (en) 1998-01-02 2002-04-23 Pfizer Prod Inc Novel erythromycin derivatives.
EP1437360A3 (fr) * 1998-08-19 2005-04-06 Pfizer Products Inc. C11-carbamates des macrolides antibactériens
US6043227A (en) * 1998-08-19 2000-03-28 Pfizer Inc. C11 carbamates of macrolide antibacterials
EP1754700A3 (fr) 1999-01-27 2007-05-09 Kosan Biosciences, Inc. synthese de polycetides
JP2002542197A (ja) 1999-04-16 2002-12-10 オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド ケトライド抗菌剤
US6590083B1 (en) 1999-04-16 2003-07-08 Ortho-Mcneil Pharmaceutical, Inc. Ketolide antibacterials
US6451768B1 (en) 1999-04-16 2002-09-17 Kosan Biosciences, Inc. Macrolide antiinfective agents
TR200103395T2 (tr) 1999-05-24 2002-04-22 Pfizer Products Inc. 13-metil eritromisin türevleri.
JPWO2003072589A1 (ja) * 2002-02-26 2005-06-16 明治製菓株式会社 新規１５員環アザライド及び新規１６員環ジアザライド誘導体とその製造法
DE602005009381D1 (de) 2004-09-23 2008-10-09 Schering Plough Ltd Bekämpfung von parasiten in tieren durch verwendung neuer trifluormethansulfonanilidoximetherderivate
DE602005017419D1 (de) * 2004-11-19 2009-12-10 Schering Plough Ltd Kontrolle von parasiten bei tieren mittels verwendung von parasitiziden 2-phenyl-3-(1h-pyrrol-2-yl) acrylonitril-derivaten
EA011281B1 (ru) 2004-12-21 2009-02-27 Пфайзер Продактс Инк. Макролиды
AR054380A1 (es) * 2005-06-09 2007-06-20 Schering Plough Ltd Control de parasitos en animales con derivados de n- ((feniloxi) fenil) -1,1,1-trifluorometansulfonamida y de n-(fenilsulfanil) fenil) -1,1,1-trifluorometansulfonamida
US8119667B2 (en) * 2005-12-29 2012-02-21 Schering-Plough Animal Health Corporation Carbonates of fenicol antibiotics
US20070238700A1 (en) * 2006-04-10 2007-10-11 Winzenberg Kevin N N-phenyl-1,1,1-trifluoromethanesulfonamide hydrazone derivative compounds and their usage in controlling parasites
EP2102154A1 (fr) * 2006-12-13 2009-09-23 Schering-Plough Ltd. Promédicaments solubles dans l'eau de chloramphénicol, thiamphénicol et analogues de ceux-ci
MX2009006282A (es) * 2006-12-13 2009-06-23 Schering Plough Ltd Profarmacos solubles en agua de florfenicol y sus analogos.
TWI430995B (zh) 2007-06-26 2014-03-21 Du Pont 萘異唑啉無脊椎有害動物控制劑
EP2182945B1 (fr) 2007-06-27 2015-08-05 E. I. du Pont de Nemours and Company Procédé de lutte contre les parasites des animaux
WO2009064953A1 (fr) * 2007-11-15 2009-05-22 Enanta Pharmaceuticals, Inc. Utilisation de dérivés de tylosine ou de macrolides pontés pour le traitement d'affections intestinales inflammatoires non spécifiques
TWI468407B (zh) 2008-02-06 2015-01-11 Du Pont 中離子農藥
JP2011529895A (ja) * 2008-07-30 2011-12-15 インターベツト・インターナシヨナル・ベー・ベー フロルフェニコール中間体として有用なオキサゾリン保護アミノジオール化合物を調製する方法
WO2011017347A2 (fr) 2009-08-05 2011-02-10 E. I. Du Pont De Nemours And Company Pesticides méso-ioniques
UA107804C2 (xx) 2009-08-05 2015-02-25 Du Pont Суміші мезоіонних пестицидів
UA110924C2 (uk) 2009-08-05 2016-03-10 Е. І. Дю Пон Де Немур Енд Компані Мезоіонні пестициди
KR20120050467A (ko) 2009-08-05 2012-05-18 이 아이 듀폰 디 네모아 앤드 캄파니 메소이온성 살충제
EP2576523B1 (fr) 2010-05-27 2016-01-13 E. I. du Pont de Nemours and Company Forme cristalline du 4-[5-[3-chloro-5-(trifluorométhyl)phényl]-4,5-dihydro-5-(trifluorométhyl)-3-isoxazolyl]-n-[2-oxo-2-[(2,2,2-trifluoroéthyl)amino]éthyl]-1-naphtalènecarboxamide
WO2012087630A1 (fr) 2010-12-20 2012-06-28 E.I. Du Pont De Nemours And Company Composés de pyridine et de pyrimidine utilisés pour lutter contre des nuisibles invertébrés
US20140011757A1 (en) * 2011-01-31 2014-01-09 Meiji Seika Pharma Co., Ltd. Novel macrolide derivative
AU2012273133A1 (en) 2011-06-20 2013-11-07 E. I. Du Pont De Nemours And Company Heterocyclic compounds for treating helminth infections
CN102260306B (zh) * 2011-07-22 2012-07-18 山东鲁抗舍里乐药业有限公司 一种制备泰拉霉素的方法
CN103958476A (zh) 2011-11-28 2014-07-30 纳幕尔杜邦公司 N-(4-喹啉基甲基)磺酰胺衍生物以及它们作为驱肠虫剂的用途
WO2013158422A1 (fr) 2012-04-17 2013-10-24 E. I. Du Pont De Nemours And Company Composés hétérocycliques pour la lutte contre des animaux nuisibles invertébrés
WO2014099837A1 (fr) 2012-12-18 2014-06-26 E. I. Du Pont De Nemours And Company Sulfonamide anti-helminthique
CN103965273B (zh) * 2013-08-23 2016-05-25 普莱柯生物工程股份有限公司 一种大环内酯类化合物
CN105669798B (zh) * 2013-08-23 2019-07-26 普莱柯生物工程股份有限公司 一种大环内酯类化合物

Family Cites Families (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3652537A (en) 1969-11-21 1972-03-28 Lilly Co Eli Epierythromycylamine and epierythromycyl b amine
US3923784A (en) 1973-09-10 1975-12-02 Hoffmann La Roche Erythromycin a derivatives
SI7910768A8 (en) 1979-04-02 1996-06-30 Pliva Pharm & Chem Works Process for pripering 11-aza-4-0-cladinosyl-6-0-desosaminyl-15-ethyl- 7,13,14-trihydroxy-3,5,7,9,12,14-hexamethyl- oxacyclopentadecane-2-one and their derivatives
US4474768A (en) 1982-07-19 1984-10-02 Pfizer Inc. N-Methyl 11-aza-10-deoxo-10-dihydro-erytromycin A, intermediates therefor
US4585759A (en) 1985-01-22 1986-04-29 Pfizer Inc. Antibacterial derivatives of a neutral macrolide
DE3860503D1 (de) 1987-09-03 1990-10-04 Pliva Pharm & Chem Works 10-dihydro-10-deoxo-11-azaerythronolid-a-verbindungen,verfahren und zwischenprodukte zu ihrer herstellung und ihre verwendung in arzneimitteln und in deren herstellung.
US5141926A (en) 1990-04-18 1992-08-25 Abbott Laboratories Erythromycin derivatives
WO1993013663A1 (fr) 1992-01-17 1993-07-22 Abbott Laboratories Procede permettant d'effectuer la biosynthese de polycetides specifiques
US5824513A (en) 1991-01-17 1998-10-20 Abbott Laboratories Recombinant DNA method for producing erythromycin analogs
US5985844A (en) 1992-03-26 1999-11-16 Merck & Co., Inc. Homoerythromycin A derivatives modified at the 4"-and 8A-positions
CA2065218A1 (fr) 1991-04-11 1992-10-12 Robert R. Wilkening Procede d'obtention de 9-desoxo-8a-aza-8a-homoerythromycine a et de ses derives 8a-alkyle
US5523399A (en) 1991-12-27 1996-06-04 Taisho Pharmaceutical Co., Ltd. 5-O-desosaminylerythronolide derivatives
FR2691464B1 (fr) * 1992-05-21 1995-06-02 Roussel Uclaf Nouveaux dérivés de la 1-oxa 6-azacyclopentadécane 13,15-dione, leur procédé de préparation et leur application comme médicaments.
US5332807A (en) * 1993-04-14 1994-07-26 Merck & Co., Inc. Process of producing 8A- and 9A-azalide antibiotics
US5441939A (en) * 1994-03-04 1995-08-15 Pfizer Inc. 3"-desmethoxy derivatives of erythromycin and azithromycin
US6271255B1 (en) 1996-07-05 2001-08-07 Biotica Technology Limited Erythromycins and process for their preparation
US6162794A (en) 1997-05-09 2000-12-19 Pfizer Inc. Erythromycin derivatives
HN1998000074A (es) * 1997-06-11 1999-01-08 Pfizer Prod Inc Derivados de macrolidos c-4 sustituidos
HN1998000086A (es) * 1997-06-11 1999-03-08 Pfizer Prod Inc Derivados de 9 - desofo - 9 aza - 9a - homoeritromicina a - c - 4 sustituidos.
US6407074B1 (en) 1997-06-11 2002-06-18 Pfizer Inc C-4″-substituted macrolide derivatives
US20020025937A1 (en) 2000-03-20 2002-02-28 Yong-Jin Wu 9-oxime erythromycin derivatives
WO1999000124A1 (fr) 1997-06-26 1999-01-07 Merck & Co., Inc. 9a-azalides, compositions a base de ces composes et procedes therapeutiques
US6339063B1 (en) 1997-09-10 2002-01-15 Merck & Co., Inc. 9a-azalides as veterinary antimicrobial agents
HN1998000159A (es) 1997-10-29 1999-02-09 Monsanto Co Derivados de 9- amino - 3 ceto eritromicina
PA8461401A1 (es) 1997-10-29 2000-05-24 Pfizer Prod Inc Derivados de eritromicina triciclicos
AP9801420A0 (en) 1998-01-02 1998-12-31 Pfizer Prod Inc Novel macrolides.
AP1060A (en) 1998-01-02 2002-04-23 Pfizer Prod Inc Novel erythromycin derivatives.
DK0941998T3 (da) 1998-03-03 2004-09-20 Pfizer Prod Inc 3,6-ketalmakrolidantibiotika
AU3439899A (en) 1998-06-03 1999-12-20 Pfizer Products Inc. Tricyclic 3-keto derivatives of 6-o-methylerythromycin
US6043227A (en) 1998-08-19 2000-03-28 Pfizer Inc. C11 carbamates of macrolide antibacterials
US6100240A (en) 1998-10-09 2000-08-08 Pfizer Inc Macrolide derivatives
CZ20011512A3 (cs) 1998-11-03 2001-09-12 Pfizer Products Inc. Nová makrolidová antibiotika
UA70972C2 (uk) 1998-11-20 2004-11-15 Пфайзер Продактс Інк. 13-членні азаліди і їх застосування як антибіотиків
TR200103395T2 (tr) 1999-05-24 2002-04-22 Pfizer Products Inc. 13-metil eritromisin türevleri.
EP1101769A3 (fr) 1999-11-18 2001-10-24 Pfizer Products Inc. Dérivés de l'érythromycine contenant de l'azote
WO2003014136A1 (fr) 2001-08-08 2003-02-20 Taisho Pharmaceutical Co., Ltd. Composes de 11a-azalide et methode de production de ces composes

Also Published As

Publication number Publication date
EP1044207A1 (fr) 2000-10-18
NO20003347D0 (no) 2000-06-27
CN1284081A (zh) 2001-02-14
ZA9811939B (en) 2000-06-30
AU756409B2 (en) 2003-01-09
BG104644A (en) 2001-01-31
UY25330A1 (es) 2000-12-29
WO1999035156A1 (fr) 1999-07-15
CA2316919C (fr) 2004-10-26
AU1444799A (en) 1999-07-26
PL341642A1 (en) 2001-04-23
HRP20000442A2 (en) 2001-04-30
AR014948A1 (es) 2001-04-11
JP2002500230A (ja) 2002-01-08
NO20003347L (no) 2000-08-28
CA2316919A1 (fr) 1999-07-15
KR100352809B1 (ko) 2002-11-01
UY25574A1 (es) 1999-09-27
WO1999035156B1 (fr) 1999-10-21
IS5528A (is) 2000-06-09
PE20000049A1 (es) 2000-02-07
HUP0100420A2 (hu) 2001-07-30
EA200000594A1 (ru) 2001-04-23
TW520374B (en) 2003-02-11
NZ504986A (en) 2003-03-28
CO4970821A1 (es) 2000-11-07
CZ20002458A3 (cs) 2001-10-17
US20040092459A1 (en) 2004-05-13
AR020851A2 (es) 2002-05-29
TNSN98238A1 (fr) 2005-03-15
AP9801420A0 (en) 1998-12-31
US6472371B1 (en) 2002-10-29
GT199800206A (es) 2000-06-21
US7015203B2 (en) 2006-03-21
HUP0100420A3 (en) 2003-07-28
KR20010024818A (ko) 2001-03-26
PA8465301A1 (es) 2000-09-29
DZ2698A1 (fr) 2003-03-29
YU41500A (sh) 2003-02-28
SK9782000A3 (en) 2001-12-03
IL137024A0 (en) 2001-06-14
AR019787A2 (es) 2002-03-13
OA11438A (en) 2004-04-30
AR020551A2 (es) 2002-05-15
BR9814601A (pt) 2000-10-17

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