BE902610A - Nouvelles anthracyclines et leur procede de fabrication. - Google Patents
Nouvelles anthracyclines et leur procede de fabrication.Info
- Publication number
- BE902610A BE902610A BE0/215148A BE215148A BE902610A BE 902610 A BE902610 A BE 902610A BE 0/215148 A BE0/215148 A BE 0/215148A BE 215148 A BE215148 A BE 215148A BE 902610 A BE902610 A BE 902610A
- Authority
- BE
- Belgium
- Prior art keywords
- manufacturing process
- hydrogen atom
- anthracyclines
- novel
- glycosides
- Prior art date
Links
- 229940045799 anthracyclines and related substance Drugs 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 229930182470 glycoside Natural products 0.000 abstract 2
- 150000002338 glycosides Chemical class 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 230000000259 anti-tumor effect Effects 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
- C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Furan Compounds (AREA)
Abstract
Des glycosides d'anthracyclines exercant une activité antitumeur et répondant à la formule générale I ou II : où R1 représente un atome d'hydrogène ou un groupe méthoxy et R2 représente un atome d'hydrogène ou un groupe hydroxy. L'invention concerne également les sels d'addition d'acide pharmaceutiquement acceptables de ces glycosides.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB848414619A GB8414619D0 (en) | 1984-06-08 | 1984-06-08 | Anthracyclines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BE902610A true BE902610A (fr) | 1985-09-30 |
Family
ID=10562109
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BE0/215148A BE902610A (fr) | 1984-06-08 | 1985-06-07 | Nouvelles anthracyclines et leur procede de fabrication. |
Country Status (4)
| Country | Link |
|---|---|
| JP (1) | JPH0631297B2 (fr) |
| BE (1) | BE902610A (fr) |
| DE (1) | DE3520469A1 (fr) |
| GB (1) | GB8414619D0 (fr) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1995016693A3 (fr) * | 1993-12-13 | 1995-07-20 | Pharmacia Spa | Derives de 4'-o-sulfonyl-anthracycline |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9418260D0 (en) * | 1994-09-09 | 1994-10-26 | Erba Carlo Spa | Anthracycline derivatives |
| CN100354561C (zh) | 2001-12-11 | 2007-12-12 | 萱场工业株式会社 | 电磁比例流量控制阀 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4345068A (en) * | 1979-11-22 | 1982-08-17 | Farmitalia Carlo Erba S.P.A. | Process for the preparation of 4'-epidaunorubicin, 3',4'-diepidaunorubicin, their doxorubicin analogs, and intermediates used in said process |
| US4438105A (en) * | 1982-04-19 | 1984-03-20 | Farmaitalia Carlo Erba S.P.A | 4'-Iododerivatives of anthracycline glycosides |
| GB8321676D0 (en) * | 1983-08-11 | 1983-09-14 | Erba Farmitalia | 4'-haloanthrocycline glycosides |
-
1984
- 1984-06-08 GB GB848414619A patent/GB8414619D0/en active Pending
-
1985
- 1985-06-06 JP JP60121633A patent/JPH0631297B2/ja not_active Expired - Lifetime
- 1985-06-07 DE DE19853520469 patent/DE3520469A1/de not_active Ceased
- 1985-06-07 BE BE0/215148A patent/BE902610A/fr not_active IP Right Cessation
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1995016693A3 (fr) * | 1993-12-13 | 1995-07-20 | Pharmacia Spa | Derives de 4'-o-sulfonyl-anthracycline |
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0631297B2 (ja) | 1994-04-27 |
| DE3520469A1 (de) | 1985-12-12 |
| GB8414619D0 (en) | 1984-07-11 |
| JPS611697A (ja) | 1986-01-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RE | Patent lapsed |
Owner name: FARMITALIA CARLO ERBA S.P.A. Effective date: 19950630 |