BE903699A - Nouveaux derives d'imidazopyridazine, leur procede de production et composition pharmaceutique les contenant. - Google Patents
Nouveaux derives d'imidazopyridazine, leur procede de production et composition pharmaceutique les contenant.Info
- Publication number
- BE903699A BE903699A BE0/215903A BE215903A BE903699A BE 903699 A BE903699 A BE 903699A BE 0/215903 A BE0/215903 A BE 0/215903A BE 215903 A BE215903 A BE 215903A BE 903699 A BE903699 A BE 903699A
- Authority
- BE
- Belgium
- Prior art keywords
- pharmaceutical composition
- composition containing
- production process
- atom
- imidazopyridazine derivatives
- Prior art date
Links
- 150000005233 imidazopyridazines Chemical class 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 229910003827 NRaRb Inorganic materials 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000000840 anti-viral effect Effects 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000005842 heteroatom Chemical group 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 125000006239 protecting group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Virology (AREA)
- Oncology (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Composés de formule ci-dessous, dans laquelle R1, R3 et R4 représentent chacun, indépendamment, H ou un groupe protecteur ; R2 est un atome d'halogène ou un groupe -NRaRb (dans lequel Ra et Rb, identiques ou différents, représentent chacun un atome H ou un groupe alkyle ; ou bien Ra et Rb peuvent former conjointement avec l'atome d'azote auquel ils sont liés un noyau hétérocyclique pouvant contenir un autre hétéro-atome), et leurs équivalents physiologiques ainsi que leurs sels d'addition d'acides. Les composés exercent une activité anti-virale.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB848429694A GB8429694D0 (en) | 1984-11-23 | 1984-11-23 | Chemical compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BE903699A true BE903699A (fr) | 1986-05-22 |
Family
ID=10570196
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BE0/215903A BE903699A (fr) | 1984-11-23 | 1985-11-22 | Nouveaux derives d'imidazopyridazine, leur procede de production et composition pharmaceutique les contenant. |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US4690917A (fr) |
| JP (1) | JPS61165385A (fr) |
| KR (1) | KR860004078A (fr) |
| CN (1) | CN85109195A (fr) |
| AU (1) | AU5029985A (fr) |
| BE (1) | BE903699A (fr) |
| DE (1) | DE3541358A1 (fr) |
| DK (1) | DK540185A (fr) |
| ES (2) | ES8704947A1 (fr) |
| FI (1) | FI854619A7 (fr) |
| FR (1) | FR2573764A1 (fr) |
| GB (2) | GB8429694D0 (fr) |
| GR (1) | GR852829B (fr) |
| IT (1) | IT1181736B (fr) |
| LU (1) | LU86178A1 (fr) |
| NL (1) | NL8503225A (fr) |
| NO (1) | NO854692L (fr) |
| PT (1) | PT81540B (fr) |
| SE (1) | SE8505534L (fr) |
| ZA (1) | ZA858964B (fr) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5137876A (en) * | 1990-10-12 | 1992-08-11 | Merck & Co., Inc. | Nucleoside antiviral and anti-inflammatory compounds and compositions and methods for using same |
| WO2000020033A1 (fr) * | 1998-10-05 | 2000-04-13 | Eisai Co., Ltd. | Comprimes se delitant immediatement dans la cavite buccale |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3998999A (en) * | 1975-10-20 | 1976-12-21 | Hoffmann-La Roche Inc. | Process for preparing pyrazomycin and pyrazomycin B |
| US4092472A (en) * | 1976-07-30 | 1978-05-30 | University Of Utah | 2,4-Dichloro-5-(β-D-ribofuranosyl) pyrimidines and substituted derivatives |
| US4096321A (en) * | 1976-11-22 | 1978-06-20 | Hoffmann-La Roche Inc. | Process to produce oxazinomycin and intermediates |
| GB1583911A (en) * | 1977-02-09 | 1981-02-04 | Allen & Hanburys Ltd | Imidazopyridazines and their use as therapeutic agents |
| US4584369A (en) * | 1981-07-31 | 1986-04-22 | Sloan-Kettering Institute For Cancer Research | Anti-leukemic beta-glycosyl C-nucleosides |
-
1984
- 1984-11-23 GB GB848429694A patent/GB8429694D0/en active Pending
-
1985
- 1985-11-21 FR FR8517238A patent/FR2573764A1/fr active Pending
- 1985-11-22 BE BE0/215903A patent/BE903699A/fr not_active IP Right Cessation
- 1985-11-22 LU LU86178A patent/LU86178A1/de unknown
- 1985-11-22 NL NL8503225A patent/NL8503225A/nl not_active Application Discontinuation
- 1985-11-22 ES ES549190A patent/ES8704947A1/es not_active Expired
- 1985-11-22 AU AU50299/85A patent/AU5029985A/en not_active Abandoned
- 1985-11-22 NO NO854692A patent/NO854692L/no unknown
- 1985-11-22 JP JP60261614A patent/JPS61165385A/ja active Pending
- 1985-11-22 FI FI854619A patent/FI854619A7/fi not_active Application Discontinuation
- 1985-11-22 ZA ZA858964A patent/ZA858964B/xx unknown
- 1985-11-22 SE SE8505534A patent/SE8505534L/xx not_active Application Discontinuation
- 1985-11-22 DE DE19853541358 patent/DE3541358A1/de not_active Withdrawn
- 1985-11-22 PT PT81540A patent/PT81540B/pt unknown
- 1985-11-22 GR GR852829A patent/GR852829B/el unknown
- 1985-11-22 KR KR1019850008735A patent/KR860004078A/ko not_active Withdrawn
- 1985-11-22 GB GB08528766A patent/GB2167419B/en not_active Expired
- 1985-11-22 DK DK540185A patent/DK540185A/da not_active Application Discontinuation
- 1985-11-22 US US06/800,667 patent/US4690917A/en not_active Expired - Fee Related
- 1985-11-22 CN CN198585109195A patent/CN85109195A/zh active Pending
- 1985-11-22 IT IT48819/85A patent/IT1181736B/it active
-
1986
- 1986-07-16 ES ES556894A patent/ES8707254A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| NL8503225A (nl) | 1986-06-16 |
| KR860004078A (ko) | 1986-06-16 |
| SE8505534D0 (sv) | 1985-11-22 |
| FI854619L (fi) | 1986-05-24 |
| FI854619A0 (fi) | 1985-11-22 |
| ES556894A0 (es) | 1987-07-16 |
| FR2573764A1 (fr) | 1986-05-30 |
| GB8528766D0 (en) | 1985-12-24 |
| IT8548819A0 (it) | 1985-11-22 |
| GR852829B (fr) | 1986-03-21 |
| GB2167419B (en) | 1988-03-23 |
| JPS61165385A (ja) | 1986-07-26 |
| ES8704947A1 (es) | 1987-04-16 |
| FI854619A7 (fi) | 1986-05-24 |
| PT81540B (en) | 1987-09-21 |
| AU5029985A (en) | 1986-05-29 |
| DK540185D0 (da) | 1985-11-22 |
| GB2167419A (en) | 1986-05-29 |
| DK540185A (da) | 1986-05-24 |
| ES8707254A1 (es) | 1987-07-16 |
| PT81540A (en) | 1985-12-01 |
| ES549190A0 (es) | 1987-04-16 |
| GB8429694D0 (en) | 1985-01-03 |
| CN85109195A (zh) | 1986-11-05 |
| DE3541358A1 (de) | 1986-05-28 |
| LU86178A1 (de) | 1986-06-04 |
| IT1181736B (it) | 1987-09-30 |
| ZA858964B (en) | 1987-07-29 |
| SE8505534L (sv) | 1986-05-24 |
| NO854692L (no) | 1986-05-26 |
| US4690917A (en) | 1987-09-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RE | Patent lapsed |
Owner name: GLAXO GROUP LTD Effective date: 19881130 |