BE903701A - Composition aqueuse de cromoglycate de sodium. - Google Patents
Composition aqueuse de cromoglycate de sodium.Info
- Publication number
- BE903701A BE903701A BE0/215905A BE215905A BE903701A BE 903701 A BE903701 A BE 903701A BE 0/215905 A BE0/215905 A BE 0/215905A BE 215905 A BE215905 A BE 215905A BE 903701 A BE903701 A BE 903701A
- Authority
- BE
- Belgium
- Prior art keywords
- sodium cromoglycate
- aqueous composition
- formulation
- cromoglycate
- sodium
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 3
- 229960000265 cromoglicic acid Drugs 0.000 title abstract 2
- IMZMKUWMOSJXDT-UHFFFAOYSA-N cromoglycic acid Chemical group O1C(C(O)=O)=CC(=O)C2=C1C=CC=C2OCC(O)COC1=CC=CC2=C1C(=O)C=C(C(O)=O)O2 IMZMKUWMOSJXDT-UHFFFAOYSA-N 0.000 title abstract 2
- 238000009472 formulation Methods 0.000 abstract 2
- 206010027654 Allergic conditions Diseases 0.000 abstract 1
- 239000013011 aqueous formulation Substances 0.000 abstract 1
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 abstract 1
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 abstract 1
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 abstract 1
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Ophthalmology & Optometry (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Otolaryngology (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Detergent Compositions (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Steroid Compounds (AREA)
Abstract
Composition aqueuse de cromoglycate de sodium qui a une viscosité de 2 à 300mPa.s et contient de préférence de l'hydroxypropylméthylcellulose. Procédé de traitement des affections allergiques de l'oeil et du nez au moyen de la composition. Dans une forme de réalisation préférée, l'hydroxypropylméthylcellulose contient 20 à 30 % de radicaux méthoxy et 4 à 12 % de radicaux hydroxypropoxy et a une température de gélification en milieu aqueux entre 45 et 90 degrés C.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US67428284A | 1984-11-23 | 1984-11-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BE903701A true BE903701A (fr) | 1986-05-22 |
Family
ID=24706028
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BE0/215905A BE903701A (fr) | 1984-11-23 | 1985-11-22 | Composition aqueuse de cromoglycate de sodium. |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP0183457B1 (fr) |
| JP (1) | JPH0639379B2 (fr) |
| AT (1) | ATE71524T1 (fr) |
| AU (2) | AU4999785A (fr) |
| BE (1) | BE903701A (fr) |
| CA (1) | CA1267848A (fr) |
| CH (1) | CH666816A5 (fr) |
| DE (1) | DE3585211D1 (fr) |
| DK (1) | DK541285A (fr) |
| FR (1) | FR2573652B1 (fr) |
| GB (1) | GB2167300B (fr) |
| GR (1) | GR852791B (fr) |
| IE (1) | IE59195B1 (fr) |
| IL (1) | IL77086A0 (fr) |
| LU (1) | LU86172A1 (fr) |
| NZ (1) | NZ214295A (fr) |
| PT (1) | PT81538A (fr) |
| ZA (1) | ZA858914B (fr) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1317226C (fr) * | 1987-05-04 | 1993-05-04 | Phillip E. Pennell | Liquide visco-elastique pour chirurgie ophtalmique et methode d'utilisation |
| ES2012532A6 (es) * | 1988-07-15 | 1990-04-01 | Cusi Lab | Un procedimiento para la preparacion de una solucion acuosa de b-metil-4-(2' -tienilcarbonil)fenilacetato de lisina para aplicacion topica oftalmica. |
| IL97075A0 (en) * | 1990-02-14 | 1992-03-29 | Alcon Lab Inc | Topical pharmaceutical composition containing an alkyl saccharide |
| DE19539532C2 (de) * | 1995-10-24 | 1999-02-25 | Mann Gerhard Chem Pharm Fab | Ophthalmisches Cromoglicat-Gelpräparat |
| WO2000042986A2 (fr) * | 1999-01-19 | 2000-07-27 | Dr. Gerhard Mann Chem.-Pharm. Fabrik Gmbh | Liquide lacrymal artificiel en gel |
| JP5364658B2 (ja) * | 2000-07-21 | 2013-12-11 | ロート製薬株式会社 | 点眼剤 |
| JP2002097129A (ja) * | 2000-07-21 | 2002-04-02 | Rohto Pharmaceut Co Ltd | 点眼剤 |
| WO2005003111A1 (fr) * | 2003-07-04 | 2005-01-13 | Astellas Pharma Inc. | Agent de prevention ou de traitement de la conjonctivite virale |
| FR2860718B1 (fr) * | 2003-10-09 | 2006-02-24 | Jean Pascal Conduzorgues | Nouvelle formulation et ses applications dans le domaines cosmetiques ou pharmaceutiques |
| ES2457442T3 (es) * | 2009-05-08 | 2014-04-25 | Pari Pharma Gmbh | Formulaciones farmacéuticas concentradas estabilizadoras de los mastocitos |
| JP2013231185A (ja) * | 2013-06-12 | 2013-11-14 | Pfizer Products Inc | ヒドロキシプロピルメチルセルロース硬カプセルおよび製造方法 |
| EP3725311A1 (fr) | 2014-02-10 | 2020-10-21 | Respivant Sciences GmbH | Procédés de traitement de maladies pulmonaires à l'aide de stabilisateurs de mastocytes |
| EP3653207A1 (fr) | 2014-02-10 | 2020-05-20 | Respivant Sciences GmbH | Traitement de troubles systémiques par stabilisateurs de mastocytes |
| US10265296B2 (en) | 2015-08-07 | 2019-04-23 | Respivant Sciences Gmbh | Methods for the treatment of systemic disorders treatable with mast cell stabilizers, including mast cell related disorders |
| EP3331522A1 (fr) | 2015-08-07 | 2018-06-13 | Patara Pharma LLC | Méthodes de traitement de troubles liés aux mastocytes par des stabilisateurs de mastocytes |
| CN110139646A (zh) | 2016-08-31 | 2019-08-16 | 瑞思皮万特科学有限责任公司 | 用于治疗由特发性肺纤维化引起的慢性咳嗽的色甘酸组合物 |
| WO2018067341A1 (fr) | 2016-10-07 | 2018-04-12 | Patara Pharma, LLC | Compositions à base de cromolyne pour le traitement d'une fibrose pulmonaire |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1473318A (en) * | 1973-05-25 | 1977-05-11 | Fisons Ltd | Solution of 1,3-bis-2-carboxychromon-5-yloxy-propan-2-ol or salts thereof |
| US4053628A (en) * | 1971-05-12 | 1977-10-11 | Fisons Limited | Composition |
| FR2230358A2 (en) * | 1973-05-25 | 1974-12-20 | Fisons Ltd | Cromoglycate contg. solns. - contg. a second therapeutically active cpd. e.g. an antihistamine |
| IL48360A (en) * | 1974-11-09 | 1978-12-17 | Fisons Ltd | Pharmaceutical compositions for the treatment of aphthous stomatitis comprising 1,3-bis-(2-carboxychromon-5-yloxy)-2-carboxychromon-5-yloxy)-2-hydroxypropane |
| US4268519A (en) * | 1979-06-05 | 1981-05-19 | Fisons Limited | Method of treating otitis media |
| JPS5756448A (en) * | 1980-09-22 | 1982-04-05 | Mitsui Toatsu Chem Inc | Preparation of aromatic isocyanate |
-
1985
- 1985-11-15 GB GB08528190A patent/GB2167300B/en not_active Expired
- 1985-11-18 DE DE8585308367T patent/DE3585211D1/de not_active Expired - Fee Related
- 1985-11-18 EP EP85308367A patent/EP0183457B1/fr not_active Expired - Lifetime
- 1985-11-18 AT AT85308367T patent/ATE71524T1/de not_active IP Right Cessation
- 1985-11-18 IL IL77086A patent/IL77086A0/xx unknown
- 1985-11-18 AU AU49997/85A patent/AU4999785A/en not_active Abandoned
- 1985-11-20 ZA ZA858914A patent/ZA858914B/xx unknown
- 1985-11-20 LU LU86172A patent/LU86172A1/fr unknown
- 1985-11-20 GR GR852791A patent/GR852791B/el unknown
- 1985-11-21 CH CH4978/85A patent/CH666816A5/fr not_active IP Right Cessation
- 1985-11-22 PT PT81538A patent/PT81538A/pt unknown
- 1985-11-22 JP JP60261615A patent/JPH0639379B2/ja not_active Expired - Lifetime
- 1985-11-22 DK DK541285A patent/DK541285A/da not_active Application Discontinuation
- 1985-11-22 NZ NZ214295A patent/NZ214295A/xx unknown
- 1985-11-22 BE BE0/215905A patent/BE903701A/fr not_active IP Right Cessation
- 1985-11-22 IE IE294285A patent/IE59195B1/en not_active IP Right Cessation
- 1985-11-22 CA CA000496016A patent/CA1267848A/fr not_active Expired - Fee Related
- 1985-11-22 FR FR8517331A patent/FR2573652B1/fr not_active Expired
-
1989
- 1989-11-02 AU AU44311/89A patent/AU4431189A/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| GR852791B (fr) | 1986-03-21 |
| AU4999785A (en) | 1986-05-29 |
| GB8528190D0 (en) | 1985-12-18 |
| AU4431189A (en) | 1990-02-22 |
| EP0183457A2 (fr) | 1986-06-04 |
| CA1267848A (fr) | 1990-04-17 |
| IE852942L (en) | 1986-05-23 |
| ATE71524T1 (de) | 1992-02-15 |
| JPH0639379B2 (ja) | 1994-05-25 |
| DE3585211D1 (de) | 1992-02-27 |
| IE59195B1 (en) | 1994-01-26 |
| DK541285A (da) | 1986-05-24 |
| EP0183457B1 (fr) | 1992-01-15 |
| GB2167300A (en) | 1986-05-29 |
| ZA858914B (en) | 1987-07-29 |
| CH666816A5 (fr) | 1988-08-31 |
| IL77086A0 (en) | 1986-04-29 |
| PT81538A (en) | 1985-12-01 |
| LU86172A1 (fr) | 1986-03-24 |
| FR2573652A1 (fr) | 1986-05-30 |
| GB2167300B (en) | 1988-11-23 |
| DK541285D0 (da) | 1985-11-22 |
| FR2573652B1 (fr) | 1988-09-02 |
| EP0183457A3 (en) | 1987-04-15 |
| JPS61143318A (ja) | 1986-07-01 |
| NZ214295A (en) | 1988-07-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RE | Patent lapsed |
Owner name: FISONS P.L.C. Effective date: 19931130 |