BG100474A - О-арил, о-алкил, о-алкенил и о-алкинил-макролидис имуносупресивно действие - Google Patents

О-арил, о-алкил, о-алкенил и о-алкинил-макролидис имуносупресивно действие

Info

Publication number
BG100474A
BG100474A BG100474A BG10047496A BG100474A BG 100474 A BG100474 A BG 100474A BG 100474 A BG100474 A BG 100474A BG 10047496 A BG10047496 A BG 10047496A BG 100474 A BG100474 A BG 100474A
Authority
BG
Bulgaria
Prior art keywords
macrolidis
arlyl
alkynyl
alkenyl
alkyl
Prior art date
Application number
BG100474A
Other languages
Bulgarian (bg)
English (en)
Inventor
Mark Goulet
Helen Organ
William Parsons
Peter Sinclair
Frederick Wong
Original Assignee
Merck & Co. Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co. Inc. filed Critical Merck & Co. Inc.
Publication of BG100474A publication Critical patent/BG100474A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/16—Peri-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/18—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Color Printing (AREA)
BG100474A 1993-10-04 1996-04-03 О-арил, о-алкил, о-алкенил и о-алкинил-макролидис имуносупресивно действие BG100474A (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/132,072 US5565560A (en) 1991-05-13 1993-10-04 O-Aryl,O-alkyl,O-alkenyl and O-alkynylmacrolides having immunosuppressive activity
PCT/US1994/011114 WO1995009857A1 (en) 1993-10-04 1994-09-30 O-aryl, o-alkyl, o-alkenyl and o-alkynyl-macrolides having immunosuppressive activity

Publications (1)

Publication Number Publication Date
BG100474A true BG100474A (bg) 1996-12-31

Family

ID=22452330

Family Applications (1)

Application Number Title Priority Date Filing Date
BG100474A BG100474A (bg) 1993-10-04 1996-04-03 О-арил, о-алкил, о-алкенил и о-алкинил-макролидис имуносупресивно действие

Country Status (18)

Country Link
US (2) US5565560A (pt)
EP (1) EP0722448A4 (pt)
JP (1) JPH09503507A (pt)
KR (1) KR960704896A (pt)
CN (1) CN1137275A (pt)
AU (1) AU690157B2 (pt)
BG (1) BG100474A (pt)
BR (1) BR9407720A (pt)
CA (1) CA2172124A1 (pt)
CZ (1) CZ99396A3 (pt)
FI (1) FI961496A7 (pt)
HU (1) HUT74591A (pt)
LV (1) LV11547B (pt)
NO (1) NO961345L (pt)
NZ (1) NZ275203A (pt)
PL (1) PL313870A1 (pt)
SK (1) SK43096A3 (pt)
WO (1) WO1995009857A1 (pt)

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US7265150B1 (en) 1998-08-14 2007-09-04 Gpi Nil Holdings Inc. Carboxylic acids and carboxylic acid isosteres of N-heterocyclic compounds for vision and memory disorders
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US6218423B1 (en) 1998-08-14 2001-04-17 Gpi Nil Holdings, Inc. Pyrrolidine derivatives for vision and memory disorders
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US6506788B1 (en) 1998-08-14 2003-01-14 Gpi Nil Holdings, Inc. N-linked urea or carbamate of heterocyclic thioesters for vision and memory disorders
AU2002322720B2 (en) 2001-07-25 2008-11-13 Raptor Pharmaceutical Inc. Compositions and methods for modulating blood-brain barrier transport
AU2007237187B2 (en) * 2002-07-16 2010-08-05 Biotica Technology Limited Production of polyketides
DK1539157T3 (da) 2002-09-18 2013-10-07 Univ Pennsylvania Fremgangsmåde til hæmning af choroidal neovaskularisering
DE10250870A1 (de) * 2002-10-31 2004-05-13 Switch Biotech Ag Zusammensetzung enthaltend Aktivatoren von IK-Kaliumkanälen und Calcineurin-Antagonisten und deren Verwendung
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WO2006115509A2 (en) 2004-06-24 2006-11-02 Novartis Vaccines And Diagnostics Inc. Small molecule immunopotentiators and assays for their detection
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Also Published As

Publication number Publication date
WO1995009857A1 (en) 1995-04-13
SK43096A3 (en) 1996-10-02
AU8073794A (en) 1995-05-01
EP0722448A4 (en) 1998-04-29
US5532248A (en) 1996-07-02
CA2172124A1 (en) 1995-04-13
FI961496L (fi) 1996-04-03
US5565560A (en) 1996-10-15
CN1137275A (zh) 1996-12-04
AU690157B2 (en) 1998-04-23
FI961496A0 (fi) 1996-04-03
PL313870A1 (en) 1996-07-22
NO961345D0 (no) 1996-04-02
HUT74591A (en) 1997-01-28
LV11547A (lv) 1996-10-20
JPH09503507A (ja) 1997-04-08
LV11547B (en) 1997-02-20
BR9407720A (pt) 1997-03-04
NO961345L (no) 1996-06-03
EP0722448A1 (en) 1996-07-24
HU9600870D0 (en) 1996-06-28
FI961496A7 (fi) 1996-04-03
NZ275203A (en) 1998-01-26
CZ99396A3 (en) 1996-09-11
KR960704896A (ko) 1996-10-09

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