BG102733A - Нови субституирани циклични аминокиселини като фармацевтични средства - Google Patents

Нови субституирани циклични аминокиселини като фармацевтични средства

Info

Publication number
BG102733A
BG102733A BG102733A BG10273398A BG102733A BG 102733 A BG102733 A BG 102733A BG 102733 A BG102733 A BG 102733A BG 10273398 A BG10273398 A BG 10273398A BG 102733 A BG102733 A BG 102733A
Authority
BG
Bulgaria
Prior art keywords
amino acids
cyclic amino
substituted cyclic
pharmaceutical forms
new substituted
Prior art date
Application number
BG102733A
Other languages
English (en)
Other versions
BG63662B1 (bg
Inventor
David HORWELL
Justin Bryans
Clare KNEEN
Andrew Morrell
Giles RATCLIFFE
Johannes Hartenstein
Original Assignee
Warner-Lambert Company Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner-Lambert Company Llc filed Critical Warner-Lambert Company Llc
Publication of BG102733A publication Critical patent/BG102733A/bg
Publication of BG63662B1 publication Critical patent/BG63662B1/bg

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • C07C233/46—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C07C233/47—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A61P25/12—Antiepileptics; Anticonvulsants for grand-mal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/28—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and containing rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Новите субституирани циклични аминокиселини с формула се използват като фармацевтични средства при терапията на епилепсия, припадъци, хипокинезия, мозъчнo-черепни и нервнодегенеративни разстройства, депресии, уплаха, паника, болки и нервнопатологични разстройства. Изобретението се отнася и до методите за получаване на съединенията и междинните продукти.
BG102733A 1996-03-14 1998-08-28 Нови субституирани циклични аминокиселини като фармацевтични средства BG63662B1 (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1343296P 1996-03-14 1996-03-14
PCT/US1997/002295 WO1997033858A1 (en) 1996-03-14 1997-02-18 Novel substituted cyclic amino acids as pharmaceutical agents

Publications (2)

Publication Number Publication Date
BG102733A true BG102733A (bg) 1999-04-30
BG63662B1 BG63662B1 (bg) 2002-08-30

Family

ID=21759938

Family Applications (1)

Application Number Title Priority Date Filing Date
BG102733A BG63662B1 (bg) 1996-03-14 1998-08-28 Нови субституирани циклични аминокиселини като фармацевтични средства

Country Status (29)

Country Link
US (1) US6103932A (bg)
EP (1) EP0888286B1 (bg)
JP (1) JP2000506861A (bg)
KR (1) KR100512506B1 (bg)
AT (1) ATE207878T1 (bg)
AU (1) AU734173B2 (bg)
BG (1) BG63662B1 (bg)
BR (1) BR9708200A (bg)
CA (1) CA2244912C (bg)
CZ (1) CZ293759B6 (bg)
DE (1) DE69707842T2 (bg)
DK (2) DK0888286T3 (bg)
EA (1) EA002765B1 (bg)
EE (1) EE9800309A (bg)
ES (1) ES2167717T3 (bg)
GE (1) GEP20012413B (bg)
HU (1) HU224720B1 (bg)
IL (1) IL125544A (bg)
IS (1) IS1990B (bg)
MX (1) MX9806069A (bg)
NO (1) NO984205L (bg)
NZ (1) NZ331143A (bg)
PL (1) PL185991B1 (bg)
PT (1) PT888286E (bg)
SK (1) SK283295B6 (bg)
TR (1) TR199801807T2 (bg)
UA (1) UA49011C2 (bg)
WO (1) WO1997033858A1 (bg)
ZA (1) ZA972200B (bg)

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Also Published As

Publication number Publication date
TR199801807T2 (xx) 1998-12-21
NO984205L (no) 1998-09-14
CA2244912C (en) 2005-07-12
SK283295B6 (sk) 2003-05-02
EP0888286B1 (en) 2001-10-31
DK0888285T3 (da) 2002-04-08
CA2244912A1 (en) 1997-09-18
PT888286E (pt) 2002-04-29
CZ286398A3 (cs) 1999-03-17
BR9708200A (pt) 1999-07-27
IS4819A (is) 1998-08-10
KR19990087756A (ko) 1999-12-27
NZ331143A (en) 2001-06-29
SK123898A3 (en) 2000-04-10
IL125544A (en) 2002-03-10
DK0888286T3 (da) 2002-02-18
EA002765B1 (ru) 2002-08-29
GEP20012413B (en) 2001-04-25
EE9800309A (et) 1999-02-15
HUP9902136A3 (en) 2000-03-28
EP0888286A1 (en) 1999-01-07
ES2167717T3 (es) 2002-05-16
AU734173B2 (en) 2001-06-07
BG63662B1 (bg) 2002-08-30
ZA972200B (en) 1997-09-17
MX9806069A (es) 1998-11-30
IL125544A0 (en) 1999-03-12
DE69707842D1 (de) 2001-12-06
HUP9902136A2 (hu) 1999-10-28
IS1990B (is) 2005-02-15
PL185991B1 (pl) 2003-09-30
DE69707842T2 (de) 2002-05-16
KR100512506B1 (ko) 2005-12-21
WO1997033858A1 (en) 1997-09-18
HU224720B1 (en) 2006-01-30
EA199800798A1 (ru) 1999-04-29
US6103932A (en) 2000-08-15
NO984205D0 (no) 1998-09-11
PL328816A1 (en) 1999-02-15
JP2000506861A (ja) 2000-06-06
AU2051197A (en) 1997-10-01
CZ293759B6 (cs) 2004-07-14
UA49011C2 (uk) 2002-09-16
ATE207878T1 (de) 2001-11-15

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