BG103633A - 2-амино-6-(2-заместени-4-фенокси)-заместени пиридини - Google Patents
2-амино-6-(2-заместени-4-фенокси)-заместени пиридини Download PDFInfo
- Publication number
- BG103633A BG103633A BG103633A BG10363399A BG103633A BG 103633 A BG103633 A BG 103633A BG 103633 A BG103633 A BG 103633A BG 10363399 A BG10363399 A BG 10363399A BG 103633 A BG103633 A BG 103633A
- Authority
- BG
- Bulgaria
- Prior art keywords
- alkyl
- formula
- group
- nmr
- nitrogen
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/73—Unsubstituted amino or imino radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Ophthalmology & Optometry (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Rheumatology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Addiction (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3753397P | 1997-02-10 | 1997-02-10 | |
| PCT/IB1998/000112 WO1998034919A1 (en) | 1997-02-10 | 1998-01-29 | 2-amino-6-(2-substituted-4-phenoxy)-substituted-pyridines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BG103633A true BG103633A (bg) | 2000-11-30 |
Family
ID=21894849
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG103633A BG103633A (bg) | 1997-02-10 | 1999-08-03 | 2-амино-6-(2-заместени-4-фенокси)-заместени пиридини |
Country Status (44)
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20010049379A1 (en) | 1997-08-27 | 2001-12-06 | Lowe John Adams | 2-aminopyridines containing fused ring substituents |
| AU765851B2 (en) * | 1998-06-03 | 2003-10-02 | Pfizer Products Inc. | 2-aminopyridines containing fused ring substituents as nitric oxide synthase inhibitors |
| EA200100125A1 (ru) * | 1998-08-11 | 2001-08-27 | Пфайзер Продактс Инк. | Новое фармацевтическое применение ингибиторов соа |
| US7115557B2 (en) | 1998-09-25 | 2006-10-03 | Sciaticon Ab | Use of certain drugs for treating nerve root injury |
| SE9803710L (sv) | 1998-09-25 | 2000-03-26 | A & Science Invest Ab | Användning av vissa substanser för behandling av nervrotsskador |
| TR200102481T2 (tr) | 1999-02-25 | 2002-01-21 | Pfizer Products Inc. | Fazlı zincir muadili içeren 2-aminopiridinler. |
| FR2812635B1 (fr) * | 2000-08-01 | 2002-10-11 | Aventis Pharma Sa | Nouveaux composes heterocycliques, preparation et utilisation comme medicaments notamment comme anti- bacteriens |
| GB0019006D0 (en) * | 2000-08-04 | 2000-09-20 | Astrazeneca Ab | Novel compounds |
| US20030232739A1 (en) * | 2001-08-15 | 2003-12-18 | Pfizer Inc. | Pharmaceutical combinations comprising a NOS inhibitor and an NMDA receptor antagonist |
| US20030045449A1 (en) * | 2001-08-15 | 2003-03-06 | Pfizer, Inc. | Pharmaceutical combinations for the treatment of neurodegenerative diseases |
| DOP2002000467A (es) * | 2001-10-10 | 2003-04-15 | Pfizer Prod Inc | 2-amino-6 (fenilo sustituido en las posiciones 2,4,5)-piridinas |
| US6803470B2 (en) | 2001-10-10 | 2004-10-12 | Pfizer Inc | 2-amino-6-(2,4,5-substituted-phenyl)-pyridines |
| US7045652B2 (en) * | 2002-07-03 | 2006-05-16 | Pfizer Inc | Processes for preparing substituted aryl boronic acids |
| US20040092741A1 (en) * | 2002-11-08 | 2004-05-13 | Pfizer Inc | Substituted pyridines via boronic acid coupling |
| WO2005007627A1 (ja) * | 2003-07-18 | 2005-01-27 | Nihon Nohyaku Co., Ltd. | フェニルピリジン誘導体、その中間体及びこれを有効成分とする除草剤 |
| CA2598484A1 (en) * | 2005-02-21 | 2006-08-24 | Proximagen Ltd. | Inhibition or treatment of dyskinesia |
| GB0607196D0 (en) * | 2006-04-11 | 2006-05-17 | Prosidion Ltd | G-protein coupled receptor agonists |
| WO2008080938A1 (en) * | 2006-12-28 | 2008-07-10 | Basf Se | Use 2-substituted pyridines for cancer treatment |
| UA105182C2 (ru) | 2008-07-03 | 2014-04-25 | Ньюрексон, Інк. | Бензоксазины, бензотиазины и родственные соединения, которые имеют ингибирующую nos активность |
| EP2963027B1 (en) | 2013-02-28 | 2018-12-26 | TiumBio Co., Ltd. | Tricyclic compound and use thereof |
| AU2014346483B2 (en) * | 2013-11-07 | 2019-01-17 | The University Of Kansas | Biphenylamide derivative Hsp90 inhibitors |
| CN106573892B (zh) * | 2014-08-13 | 2019-10-25 | 明治制果药业株式会社 | 结晶性抗白癣菌药及其制备方法 |
| CN106265640B (zh) * | 2016-08-11 | 2019-05-14 | 吉林大学 | Appa在制备治疗糖尿病肾病药物中的应用 |
| CN108069831B (zh) * | 2018-01-25 | 2020-11-24 | 上海恩氟佳科技有限公司 | 一种合成2,3-二甲基-4-氟苯酚的方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1994014780A1 (en) * | 1992-12-18 | 1994-07-07 | The Wellcome Foundation Limited | Pyrimidine, pyridine, pteridinone and indazole derivatives as enzyme inhibitors |
| EP0724570B1 (en) * | 1993-10-21 | 1999-03-03 | G.D. Searle & Co. | Amidino derivatives useful as nitric oxide synthase inhibitors |
| AU4515696A (en) * | 1994-12-12 | 1996-07-03 | Merck & Co., Inc. | Substituted 2-aminopyridines as inhibitors of nitric oxide synthase |
| PT891332E (pt) * | 1996-03-29 | 2004-07-30 | Pfizer | Derivados de 6-fenilpiridil-2-amina |
-
1998
- 1998-01-29 JP JP53404898A patent/JP3505189B2/ja not_active Expired - Fee Related
- 1998-01-29 HU HU0000762A patent/HUP0000762A3/hu unknown
- 1998-01-29 AU AU55727/98A patent/AU744313B2/en not_active Ceased
- 1998-01-29 WO PCT/IB1998/000112 patent/WO1998034919A1/en not_active Ceased
- 1998-01-29 CN CNA2004100073282A patent/CN1523015A/zh active Pending
- 1998-01-29 KR KR10-1999-7007065A patent/KR100460399B1/ko not_active Expired - Fee Related
- 1998-01-29 DK DK98900635T patent/DK0958282T3/da active
- 1998-01-29 EA EA199900632A patent/EA003834B1/ru not_active IP Right Cessation
- 1998-01-29 AT AT98900635T patent/ATE271544T1/de not_active IP Right Cessation
- 1998-01-29 NZ NZ518345A patent/NZ518345A/en unknown
- 1998-01-29 SI SI9830699T patent/SI0958282T1/xx unknown
- 1998-01-29 TR TR1999/01917T patent/TR199901917T2/xx unknown
- 1998-01-29 IL IL13089898A patent/IL130898A0/xx unknown
- 1998-01-29 UA UA99084543A patent/UA64740C2/uk unknown
- 1998-01-29 YU YU35699A patent/YU35699A/sh unknown
- 1998-01-29 EP EP98900635A patent/EP0958282B1/en not_active Expired - Lifetime
- 1998-01-29 NZ NZ336623A patent/NZ336623A/xx unknown
- 1998-01-29 CN CN98802392A patent/CN1246848A/zh active Pending
- 1998-01-29 PL PL98335161A patent/PL335161A1/xx unknown
- 1998-01-29 CN CNA031086047A patent/CN1515554A/zh active Pending
- 1998-01-29 BR BR9811093-4A patent/BR9811093A/pt not_active Application Discontinuation
- 1998-01-29 CZ CZ19992769A patent/CZ292135B6/cs not_active IP Right Cessation
- 1998-01-29 PT PT98900635T patent/PT958282E/pt unknown
- 1998-01-29 ES ES98900635T patent/ES2224354T3/es not_active Expired - Lifetime
- 1998-01-29 DE DE69825147T patent/DE69825147T2/de not_active Expired - Fee Related
- 1998-01-29 CA CA002277990A patent/CA2277990C/en not_active Expired - Fee Related
- 1998-01-29 SK SK1011-99A patent/SK101199A3/sk unknown
- 1998-02-03 TW TW087101311A patent/TW458969B/zh not_active IP Right Cessation
- 1998-02-05 AP APAP/P/1998/001178A patent/AP833A/en active
- 1998-02-05 PE PE1998000082A patent/PE58599A1/es not_active Application Discontinuation
- 1998-02-06 MY MYPI98000488A patent/MY120976A/en unknown
- 1998-02-06 UY UY24881A patent/UY24881A1/es not_active Application Discontinuation
- 1998-02-09 DZ DZ980024A patent/DZ2414A1/xx active
- 1998-02-09 ZA ZA9801017A patent/ZA981017B/xx unknown
- 1998-02-09 MA MA24958A patent/MA27676A1/fr unknown
- 1998-02-09 HN HN1998000030A patent/HN1998000030A/es unknown
- 1998-02-09 AR ARP980100551A patent/AR011117A1/es not_active Application Discontinuation
- 1998-02-09 TN TNTNSN98024A patent/TNSN98024A1/fr unknown
- 1998-02-10 HR HR60/037,533A patent/HRP980069A2/hr not_active Application Discontinuation
- 1998-02-10 PA PA19988446301A patent/PA8446301A1/es unknown
- 1998-02-10 CO CO98006875A patent/CO4920225A1/es unknown
- 1998-02-11 GT GT199800032A patent/GT199800032A/es unknown
- 1998-07-31 US US09/127,158 patent/US20010007873A1/en not_active Abandoned
-
1999
- 1999-07-16 IS IS5118A patent/IS5118A/is unknown
- 1999-08-03 BG BG103633A patent/BG103633A/bg unknown
- 1999-08-06 OA OA9900173A patent/OA11084A/en unknown
- 1999-08-09 NO NO19993823A patent/NO314803B1/no unknown
-
2003
- 2003-02-20 US US10/371,357 patent/US20030162765A1/en not_active Abandoned
Also Published As
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