BG103737A - Метод за получаване на производни на 4н-4-оксо- хинолизин-3-карбоксилна киселина - Google Patents

Метод за получаване на производни на 4н-4-оксо- хинолизин-3-карбоксилна киселина

Info

Publication number
BG103737A
BG103737A BG103737A BG10373799A BG103737A BG 103737 A BG103737 A BG 103737A BG 103737 A BG103737 A BG 103737A BG 10373799 A BG10373799 A BG 10373799A BG 103737 A BG103737 A BG 103737A
Authority
BG
Bulgaria
Prior art keywords
derivatives
preparation
quinolysine
oxo
carboxylic acid
Prior art date
Application number
BG103737A
Other languages
English (en)
Inventor
Wei - Bo WANG
Francis KERDESKY
Chi - Nung HSIAO
Qun Li
Daniel Chu
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Publication of BG103737A publication Critical patent/BG103737A/bg

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
    • C07D455/02—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing not further condensed quinolizine ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Изобретението се отнася до метод за получаване насъединение с формула, в която R1, R2, R3, R4 и R5имат значенията, посочени в описанието, от енаминчрез разширяване на веригата и затваряне на пръстен, последвано от допълнително получаване на производни, третиране с 3-алкоксиакрилоилово съединение, още едно затваряне на пръстен и превръщане на хидроксилната група в отцепваща се.
BG103737A 1997-02-26 1999-09-16 Метод за получаване на производни на 4н-4-оксо- хинолизин-3-карбоксилна киселина BG103737A (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/806,806 US5693813A (en) 1997-02-26 1997-02-26 Process for preparation of 4H-4-oxo-quinolizine-3-carboxylic acid
PCT/US1998/002327 WO1998038191A1 (en) 1997-02-26 1998-02-06 Process for preparation of 4h-4-oxo-quinolizine-3-carboxylic acid derivatives

Publications (1)

Publication Number Publication Date
BG103737A true BG103737A (bg) 2000-06-30

Family

ID=25194886

Family Applications (1)

Application Number Title Priority Date Filing Date
BG103737A BG103737A (bg) 1997-02-26 1999-09-16 Метод за получаване на производни на 4н-4-оксо- хинолизин-3-карбоксилна киселина

Country Status (27)

Country Link
US (1) US5693813A (bg)
EP (1) EP0971919B1 (bg)
JP (1) JP2001513104A (bg)
KR (1) KR20000075700A (bg)
CN (1) CN1248256A (bg)
AR (1) AR011167A1 (bg)
AT (1) ATE207920T1 (bg)
AU (1) AU724353B2 (bg)
BG (1) BG103737A (bg)
BR (1) BR9807726A (bg)
CA (1) CA2281734A1 (bg)
CO (1) CO4920239A1 (bg)
CZ (1) CZ290252B6 (bg)
DE (1) DE69802274T2 (bg)
DK (1) DK0971919T3 (bg)
ES (1) ES2168740T3 (bg)
HU (1) HUP0001323A3 (bg)
IL (1) IL131050A0 (bg)
NO (1) NO994108L (bg)
NZ (1) NZ336876A (bg)
PL (1) PL335373A1 (bg)
PT (1) PT971919E (bg)
SK (1) SK115299A3 (bg)
TR (1) TR199901956T2 (bg)
TW (1) TW444017B (bg)
WO (1) WO1998038191A1 (bg)
ZA (1) ZA98836B (bg)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011031745A1 (en) 2009-09-09 2011-03-17 Achaogen, Inc. Antibacterial fluoroquinolone analogs
CN106432222A (zh) * 2016-09-19 2017-02-22 丹诺医药(苏州）有限公司 8‑氯‑1‑环丙基‑7‑氟‑9‑甲基‑4‑氧‑4‑氢‑喹嗪‑3‑羧酸酯及其制备方法
CN106543170B (zh) * 2016-10-27 2018-02-23 丹诺医药(苏州）有限公司 8‑氯‑1‑环丙基‑7‑氟‑9‑甲基‑4‑氧‑4‑氢‑喹嗪‑3‑羧酸酯及其合成方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5599816A (en) * 1990-05-02 1997-02-04 Abbott Laboratories Quinolizinone type compounds
JP2514136B2 (ja) * 1990-05-02 1996-07-10 アボツト・ラボラトリーズ キノリジノン型化合物
EP0723545B1 (en) * 1993-10-14 2002-05-08 Abbott Laboratories Quinolizinone type compounds
KR19990022524A (ko) * 1995-06-06 1999-03-25 웨인스톡 스티븐 에프. 퀴놀리지논형화합물

Also Published As

Publication number Publication date
SK115299A3 (en) 2000-01-18
AR011167A1 (es) 2000-08-02
WO1998038191A1 (en) 1998-09-03
DE69802274T2 (de) 2002-07-18
HUP0001323A3 (en) 2001-01-29
KR20000075700A (ko) 2000-12-26
HUP0001323A2 (hu) 2000-10-28
ATE207920T1 (de) 2001-11-15
NO994108D0 (no) 1999-08-25
DE69802274D1 (de) 2001-12-06
CZ290252B6 (cs) 2002-06-12
AU724353B2 (en) 2000-09-21
EP0971919A1 (en) 2000-01-19
ZA98836B (en) 1998-08-05
CZ288199A3 (cs) 1999-11-17
CN1248256A (zh) 2000-03-22
PL335373A1 (en) 2000-04-25
US5693813A (en) 1997-12-02
NZ336876A (en) 2000-12-22
AU6271898A (en) 1998-09-18
CO4920239A1 (es) 2000-05-29
TR199901956T2 (xx) 1999-10-21
PT971919E (pt) 2002-04-29
IL131050A0 (en) 2001-01-28
ES2168740T3 (es) 2002-06-16
TW444017B (en) 2001-07-01
NO994108L (no) 1999-10-25
JP2001513104A (ja) 2001-08-28
DK0971919T3 (da) 2002-01-28
BR9807726A (pt) 2000-02-15
EP0971919B1 (en) 2001-10-31
CA2281734A1 (en) 1998-09-03

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