BG105128A - Therapeutic combinations of selective estrogen receptor modulators (serm) and growth hormone secretagogues (ghs) for treating musculoskeletal frailty - Google Patents

Therapeutic combinations of selective estrogen receptor modulators (serm) and growth hormone secretagogues (ghs) for treating musculoskeletal frailty

Info

Publication number: BG105128A
Authority: BG; Bulgaria
Prior art keywords: ghs; serm; growth hormone; compositions; estrogen receptor
Prior art date: 1998-06-16

Application number

BG105128A

Other languages

Bulgarian (bg)

English (en)

Inventor

Hua KE

Mei Li

Lydia PAN

David Thompson

Original Assignee

Pfizer Products Inc.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-06-16

Filing date

2001-01-08

Publication date

2001-11-30

2001-01-08 Application filed by Pfizer Products Inc. filed Critical Pfizer Products Inc.

2001-11-30 Publication of BG105128A publication Critical patent/BG105128A/xx

Links

208000036119 Frailty Diseases 0.000 title abstract 2
206010003549 asthenia Diseases 0.000 title abstract 2
239000003324 growth hormone secretagogue Substances 0.000 title 1
239000000333 selective estrogen receptor modulator Substances 0.000 title 1
229940095743 selective estrogen receptor modulator Drugs 0.000 title 1
230000001225 therapeutic effect Effects 0.000 title 1
239000000203 mixture Substances 0.000 abstract 4
150000003839 salts Chemical class 0.000 abstract 2
208000001132 Osteoporosis Diseases 0.000 abstract 1
210000000988 bone and bone Anatomy 0.000 abstract 1
GXESHMAMLJKROZ-IAPPQJPRSA-N lasofoxifene Chemical compound C1([C@@H]2[C@@H](C3=CC=C(C=C3CC2)O)C=2C=CC(OCCN3CCCC3)=CC=2)=CC=CC=C1 GXESHMAMLJKROZ-IAPPQJPRSA-N 0.000 abstract 1
210000003205 muscle Anatomy 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Physical Education & Sports Medicine (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Orthopedic Medicine & Surgery (AREA)
Rheumatology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

BG105128A 1998-06-16 2001-01-08 Therapeutic combinations of selective estrogen receptor modulators (serm) and growth hormone secretagogues (ghs) for treating musculoskeletal frailty BG105128A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US8942498P	1998-06-16	1998-06-16
PCT/IB1999/000796 WO1999065488A1 (en)	1998-06-16	1999-05-03	Therapeutic combinations of (selective) estrogen receptor modulators (serm) and growth hormone secretagogues (ghs) for treating musculoskeletal frailty

Publications (1)

Publication Number	Publication Date
BG105128A true BG105128A (en)	2001-11-30

Family

ID=22217565

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BG105128A BG105128A (en)	1998-06-16	2001-01-08	Therapeutic combinations of selective estrogen receptor modulators (serm) and growth hormone secretagogues (ghs) for treating musculoskeletal frailty

Country Status (29)

Country	Link
EP (1)	EP1085867A1 (id)
JP (1)	JP2002518328A (id)
KR (1)	KR20010052817A (id)
CN (1)	CN1305378A (id)
AP (1)	AP9901581A0 (id)
AR (1)	AR018868A1 (id)
AU (1)	AU3342099A (id)
BG (1)	BG105128A (id)
BR (1)	BR9911357A (id)
CA (1)	CA2335112A1 (id)
CO (1)	CO5070586A1 (id)
EA (1)	EA200001189A1 (id)
GT (1)	GT199900083A (id)
HR (1)	HRP20000857A2 (id)
HU (1)	HUP0102395A2 (id)
ID (1)	ID26726A (id)
IL (1)	IL139587A0 (id)
IS (1)	IS5727A (id)
MA (1)	MA26648A1 (id)
NO (1)	NO20006381L (id)
OA (1)	OA11569A (id)
PA (1)	PA8472101A1 (id)
PE (1)	PE20000633A1 (id)
PL (1)	PL345064A1 (id)
SK (1)	SK18902000A3 (id)
TN (1)	TNSN99118A1 (id)
UY (1)	UY25557A1 (id)
WO (1)	WO1999065488A1 (id)
ZA (1)	ZA993973B (id)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1004306A3 (en) *	1998-08-06	2000-06-07	Pfizer Products Inc.	Estrogen agonists/antagonists
CA2420535A1 (en) *	2000-08-30	2002-03-07	Mary Tanya Am Ende	Sustained release formulations for growth hormone secretagogues
IL145106A0 (en) *	2000-08-30	2002-06-30	Pfizer Prod Inc	Intermittent administration of a geowth hormone secretagogue
MXPA04005112A (es) *	2001-11-29	2005-04-29	Gtx Inc	Prevencion y tratamiento de osteoporosis inducida por privacion de androgeno.
US7524866B2 (en)	2001-11-29	2009-04-28	Gtx, Inc.	Prevention and treatment of androgen—deprivation induced osteoporosis
US7476653B2 (en)	2003-06-18	2009-01-13	Tranzyme Pharma, Inc.	Macrocyclic modulators of the ghrelin receptor
CU23558A1 (es)	2006-02-28	2010-07-20	Ct Ingenieria Genetica Biotech	Compuestos análogos a los secretagogos peptidicos de la hormona de crecimiento
ES2602789T3 (es)	2007-02-09	2017-02-22	Ocera Therapeutics, Inc.	Productos intermedios conectores para la síntesis de moduladores macrocíclicos del receptor de la grelina

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
UA51676C2 (uk) *	1995-11-02	2002-12-16	Пфайзер Інк.	(-)цис-6(s)-феніл-5(r)[4-(2-піролідин-1-ілетокси)феніл]-5,6,7,8-тетрагідронафталін-2-ол d-тартрат, спосіб його одержання, спосіб лікування захворювань, що піддаються лікуванню агоністами естрогену, та фармацевтична композиція
TW432073B (en) *	1995-12-28	2001-05-01	Pfizer	Pyrazolopyridine compounds
HN1996000101A (es) *	1996-02-28	1997-06-26	Inc Pfizer	Terapia combinada para la osteoporosis

1999
- 1999-05-03 AU AU33420/99A patent/AU3342099A/en not_active Abandoned
- 1999-05-03 WO PCT/IB1999/000796 patent/WO1999065488A1/en not_active Ceased
- 1999-05-03 IL IL13958799A patent/IL139587A0/xx unknown
- 1999-05-03 EA EA200001189A patent/EA200001189A1/ru unknown
- 1999-05-03 OA OA1200000346A patent/OA11569A/en unknown
- 1999-05-03 CN CN99807381A patent/CN1305378A/zh active Pending
- 1999-05-03 KR KR1020007014140A patent/KR20010052817A/ko not_active Ceased
- 1999-05-03 EP EP99914723A patent/EP1085867A1/en not_active Withdrawn
- 1999-05-03 JP JP2000554368A patent/JP2002518328A/ja active Pending
- 1999-05-03 PL PL99345064A patent/PL345064A1/xx unknown
- 1999-05-03 HU HU0102395A patent/HUP0102395A2/hu unknown
- 1999-05-03 HR HR20000857A patent/HRP20000857A2/hr not_active Application Discontinuation
- 1999-05-03 CA CA002335112A patent/CA2335112A1/en not_active Abandoned
- 1999-05-03 SK SK1890-2000A patent/SK18902000A3/sk unknown
- 1999-05-03 BR BR9911357-0A patent/BR9911357A/pt not_active Application Discontinuation
- 1999-05-03 ID IDW20002604A patent/ID26726A/id unknown
- 1999-05-07 PA PA19998472101A patent/PA8472101A1/es unknown
- 1999-06-10 AP APAP/P/1999/001581A patent/AP9901581A0/en unknown
- 1999-06-11 UY UY25557A patent/UY25557A1/es not_active Application Discontinuation
- 1999-06-11 PE PE1999000522A patent/PE20000633A1/es not_active Application Discontinuation
- 1999-06-14 GT GT199900083A patent/GT199900083A/es unknown
- 1999-06-15 ZA ZA9903973A patent/ZA993973B/xx unknown
- 1999-06-15 AR ARP990102847A patent/AR018868A1/es not_active Application Discontinuation
- 1999-06-15 MA MA25622A patent/MA26648A1/fr unknown
- 1999-06-15 TN TNTNSN99118A patent/TNSN99118A1/fr unknown
- 1999-06-16 CO CO99037624A patent/CO5070586A1/es unknown
2000
- 2000-11-24 IS IS5727A patent/IS5727A/is unknown
- 2000-12-14 NO NO20006381A patent/NO20006381L/no not_active Application Discontinuation
2001
- 2001-01-08 BG BG105128A patent/BG105128A/xx unknown

Also Published As

Publication number	Publication date
SK18902000A3 (sk)	2001-12-03
JP2002518328A (ja)	2002-06-25
PL345064A1 (en)	2001-11-19
IS5727A (is)	2000-11-24
AU3342099A (en)	2000-01-05
BR9911357A (pt)	2001-03-13
HRP20000857A2 (en)	2001-10-31
ZA993973B (en)	2000-12-15
WO1999065488A1 (en)	1999-12-23
CO5070586A1 (es)	2001-08-28
OA11569A (en)	2004-07-01
CA2335112A1 (en)	1999-12-23
NO20006381D0 (no)	2000-12-14
UY25557A1 (es)	2001-01-31
PA8472101A1 (es)	2000-09-29
HUP0102395A2 (hu)	2001-11-28
KR20010052817A (ko)	2001-06-25
AR018868A1 (es)	2001-12-12
CN1305378A (zh)	2001-07-25
PE20000633A1 (es)	2000-07-26
ID26726A (id)	2001-02-01
GT199900083A (es)	2000-12-05
AP9901581A0 (en)	1999-06-30
TNSN99118A1 (fr)	2005-11-10
EP1085867A1 (en)	2001-03-28
NO20006381L (no)	2000-12-14
EA200001189A1 (ru)	2001-06-25
IL139587A0 (en)	2002-02-10
MA26648A1 (fr)	2004-12-20

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