BG105710A - 5ht1 antagonists for antidepressant therapy - Google Patents

5ht1 antagonists for antidepressant therapy

Info

Publication number: BG105710A
Authority: BG; Bulgaria
Prior art keywords: antagonists; antidepressant therapy; compounds; antidepressant; therapy
Prior art date: 1998-12-28

Application number

BG105710A

Other languages

Bulgarian (bg)

English (en)

Inventor

Gene BRIGHT

Kishor DESAI

Original Assignee

Pfizer Products Inc.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-12-28

Filing date

2001-07-16

Publication date

2002-02-28

2001-07-16 Application filed by Pfizer Products Inc. filed Critical Pfizer Products Inc.

2002-02-28 Publication of BG105710A publication Critical patent/BG105710A/xx

Links

230000001430 anti-depressive effect Effects 0.000 title 1
239000000935 antidepressant agent Substances 0.000 title 1
229940005513 antidepressants Drugs 0.000 title 1
239000002868 serotonin 5-HT1 receptor antagonist Substances 0.000 title 1
238000002560 therapeutic procedure Methods 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 2

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Epidemiology (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Psychology (AREA)
Diabetes (AREA)
Hospice & Palliative Care (AREA)
Obesity (AREA)
Addiction (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Urology & Nephrology (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Gynecology & Obstetrics (AREA)
Child & Adolescent Psychology (AREA)
Dermatology (AREA)
Hematology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

BG105710A 1998-12-28 2001-07-16 5ht1 antagonists for antidepressant therapy BG105710A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US11395798P	1998-12-28	1998-12-28
PCT/IB1999/001772 WO2000039128A1 (en)	1998-12-28	1999-11-03	5ht1 antagonists for antidepressant therapy

Publications (1)

Publication Number	Publication Date
BG105710A true BG105710A (en)	2002-02-28

Family

ID=22352526

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BG105710A BG105710A (en)	1998-12-28	2001-07-16	5ht1 antagonists for antidepressant therapy

Country Status (43)

Country	Link
US (1)	US6525196B1 (de)
EP (1)	EP1140931B1 (de)
JP (1)	JP2002533463A (de)
KR (1)	KR100417506B1 (de)
CN (1)	CN1332740A (de)
AP (1)	AP2001002188A0 (de)
AR (1)	AR024840A1 (de)
AT (1)	ATE260278T1 (de)
AU (1)	AU761711B2 (de)
BG (1)	BG105710A (de)
BR (1)	BR9916807A (de)
CA (1)	CA2356985C (de)
CO (1)	CO5150179A1 (de)
CR (1)	CR6398A (de)
CZ (1)	CZ291163B6 (de)
DE (1)	DE69915113T2 (de)
DK (1)	DK1140931T3 (de)
DZ (1)	DZ2933A1 (de)
EA (1)	EA003099B1 (de)
EE (1)	EE04439B1 (de)
ES (1)	ES2214892T3 (de)
GE (1)	GEP20043227B (de)
GT (1)	GT199900224A (de)
HR (1)	HRP20010488A2 (de)
HU (1)	HUP0104852A3 (de)
ID (1)	ID30117A (de)
IL (1)	IL143385A0 (de)
IS (1)	IS5951A (de)
MA (1)	MA26706A1 (de)
NO (1)	NO20013215L (de)
NZ (1)	NZ511964A (de)
OA (1)	OA11742A (de)
PA (1)	PA8486701A1 (de)
PE (1)	PE20001234A1 (de)
PT (1)	PT1140931E (de)
SK (1)	SK9002001A3 (de)
TN (1)	TNSN99218A1 (de)
TR (1)	TR200101979T2 (de)
TW (1)	TW523514B (de)
UA (1)	UA62015C2 (de)
WO (1)	WO2000039128A1 (de)
YU (1)	YU44301A (de)
ZA (1)	ZA200105041B (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2003065970A2 (en) *	2001-02-20	2003-08-14	Royal College Of Surgeons Ie	Treatment of fibromyalgia and related fatigue syndromes using pindolol
GB0203778D0 (en) *	2002-02-18	2002-04-03	Glaxo Group Ltd	Compounds
AP2005003390A0 (en) *	2003-03-12	2005-09-30	Pfizer Prod Inc	Pyridyloxymethyl and benzisoxazole azabicyclic derivatives.
GB0316915D0 (en) *	2003-07-18	2003-08-20	Glaxo Group Ltd	Compounds
WO2005082370A1 (en) *	2004-01-29	2005-09-09	Pfizer Products Inc.	Combinations of an atypical antipsychotic and an aminomethylpyridyloxymethyl/benzisoxazole azabicyclic derivatives for treating cns disorders
AR048112A1 (es) *	2004-03-25	2006-03-29	Solvay Pharm Bv	Derivados de 1-(2h-1-benzopiran-2-on-8-il)-piperazina para el tratamiento de dolor
AR049478A1 (es)	2004-03-25	2006-08-09	Solvay Pharm Bv	Un procedimiento para la preparacion de 3-amino-8-(1-piperazinil)-2h-1-benzopiran-2-ona. sales e hidratos y composiciones farmaceuticas.
BRPI0515143A (pt) *	2004-09-10	2008-07-08	Pfizer Prod Inc	usos de derivados azabicìclicos de piridiloximetila e benzisoxazol para a preparação de uma composição farmacêutica para o tratamento dos distúrbios de humor
JP2008512441A (ja) *	2004-09-10	2008-04-24	ファイザー・プロダクツ・インク	ピリジルオキシメチル、及びベンズイソオキサゾール・アザビシクロ誘導体を使用する、認知障害の治療方法
DE102005026194A1 (de) *	2005-06-06	2006-12-07	Grünenthal GmbH	Substituierte N-Benzo[d]isoxazol-3-yl-amin-Derivate und deren Verwendung zur Herstellung von Arzneimitteln
WO2008019431A1 (en) *	2006-08-14	2008-02-21	Brc Operations Pty Limited	Method and compositions for simultaneously regulating memory and mood
WO2014078568A1 (en)	2012-11-14	2014-05-22	The Johns Hopkins University	Methods and compositions for treating schizophrenia
WO2020183011A1 (en)	2019-03-14	2020-09-17	Institut Curie	Htr1d inhibitors and uses thereof in the treatment of cancer
WO2021127391A1 (en) *	2019-12-20	2021-06-24	The Jackson Laboratory	Molecular targets for addiction

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5157034A (en) *	1991-02-27	1992-10-20	Pfizer Inc.	Neuroleptic perhydro-1H-pyrido[1,2-a]pyrazines
GB9410512D0 (en) *	1994-05-25	1994-07-13	Smithkline Beecham Plc	Novel treatment
US5756496A (en) *	1994-05-28	1998-05-26	Smithkline Beecham P.L.C.	Amide derivatives having 5HT1D-antagonist activity
IL132409A0 (en) *	1997-04-18	2001-03-19	Smithkline Beecham Plc	Indole derivatives having combined 5ht1a 5ht1b and 5ht1d receptor antagonist activity
IT1293807B1 (it) *	1997-08-01	1999-03-10	Recordati Chem Pharm	Derivati 1- (n-fenilaminoalchil) piperazinici sostituiti alla posizione 2 dell'anello fenilico
PA8469101A1 (es) *	1998-04-09	2000-09-29	Pfizer Prod Inc	Ligandos azabiciclicos de receptores 5ht1

1999
- 1999-03-11 UA UA2001064492A patent/UA62015C2/uk unknown
- 1999-04-11 AR ARP990105589A patent/AR024840A1/es unknown
- 1999-11-03 YU YU44301A patent/YU44301A/sh unknown
- 1999-11-03 AP APAP/P/2001/002188A patent/AP2001002188A0/en unknown
- 1999-11-03 AT AT99951040T patent/ATE260278T1/de not_active IP Right Cessation
- 1999-11-03 NZ NZ511964A patent/NZ511964A/en unknown
- 1999-11-03 CZ CZ20012386A patent/CZ291163B6/cs not_active IP Right Cessation
- 1999-11-03 DK DK99951040T patent/DK1140931T3/da active
- 1999-11-03 ID IDW00200101401A patent/ID30117A/id unknown
- 1999-11-03 JP JP2000591039A patent/JP2002533463A/ja active Pending
- 1999-11-03 OA OA1200100172A patent/OA11742A/en unknown
- 1999-11-03 DE DE69915113T patent/DE69915113T2/de not_active Expired - Fee Related
- 1999-11-03 CN CN99815202A patent/CN1332740A/zh active Pending
- 1999-11-03 EE EEP200100346A patent/EE04439B1/xx not_active IP Right Cessation
- 1999-11-03 PT PT99951040T patent/PT1140931E/pt unknown
- 1999-11-03 SK SK900-2001A patent/SK9002001A3/sk unknown
- 1999-11-03 EA EA200100517A patent/EA003099B1/ru not_active IP Right Cessation
- 1999-11-03 TR TR2001/01979T patent/TR200101979T2/xx unknown
- 1999-11-03 GE GEAP19995963A patent/GEP20043227B/en unknown
- 1999-11-03 IL IL14338599A patent/IL143385A0/xx unknown
- 1999-11-03 BR BR9916807-3A patent/BR9916807A/pt not_active Application Discontinuation
- 1999-11-03 WO PCT/IB1999/001772 patent/WO2000039128A1/en not_active Ceased
- 1999-11-03 CA CA002356985A patent/CA2356985C/en not_active Expired - Fee Related
- 1999-11-03 HU HU0104852A patent/HUP0104852A3/hu unknown
- 1999-11-03 KR KR10-2001-7008261A patent/KR100417506B1/ko not_active Expired - Fee Related
- 1999-11-03 AU AU63614/99A patent/AU761711B2/en not_active Ceased
- 1999-11-03 ES ES99951040T patent/ES2214892T3/es not_active Expired - Lifetime
- 1999-11-03 HR HR20010488A patent/HRP20010488A2/hr not_active Application Discontinuation
- 1999-11-03 EP EP99951040A patent/EP1140931B1/de not_active Expired - Lifetime
- 1999-11-04 PE PE1999001116A patent/PE20001234A1/es not_active Application Discontinuation
- 1999-11-05 TW TW088119374A patent/TW523514B/zh not_active IP Right Cessation
- 1999-11-10 DZ DZ990233A patent/DZ2933A1/xx active
- 1999-11-10 MA MA25844A patent/MA26706A1/fr unknown
- 1999-11-17 TN TNTNSN99218A patent/TNSN99218A1/fr unknown
- 1999-11-18 CO CO99072703A patent/CO5150179A1/es unknown
- 1999-12-06 US US09/454,509 patent/US6525196B1/en not_active Expired - Fee Related
- 1999-12-07 PA PA19998486701A patent/PA8486701A1/es unknown
- 1999-12-23 GT GT199900224A patent/GT199900224A/es unknown
2001
- 2001-05-22 IS IS5951A patent/IS5951A/is unknown
- 2001-06-19 CR CR6398A patent/CR6398A/es not_active Application Discontinuation
- 2001-06-20 ZA ZA200105041A patent/ZA200105041B/en unknown
- 2001-06-27 NO NO20013215A patent/NO20013215L/no not_active Application Discontinuation
- 2001-07-16 BG BG105710A patent/BG105710A/xx unknown

Also Published As

Publication number	Publication date
ATE260278T1 (de)	2004-03-15
GT199900224A (es)	2001-06-15
HRP20010488A2 (en)	2002-08-31
YU44301A (sh)	2004-07-15
DE69915113T2 (de)	2004-08-26
OA11742A (en)	2005-05-13
PT1140931E (pt)	2004-05-31
DE69915113D1 (de)	2004-04-01
EE04439B1 (et)	2005-02-15
IL143385A0 (en)	2002-04-21
TNSN99218A1 (fr)	2005-11-10
GEP20043227B (en)	2004-04-26
BR9916807A (pt)	2001-10-23
HUP0104852A3 (en)	2002-12-28
NO20013215L (no)	2001-08-27
CR6398A (es)	2004-03-24
PE20001234A1 (es)	2000-11-07
CZ20012386A3 (cs)	2002-02-13
HUP0104852A2 (hu)	2002-05-29
CZ291163B6 (cs)	2003-01-15
AU6361499A (en)	2000-07-31
US6525196B1 (en)	2003-02-25
PA8486701A1 (es)	2000-09-29
EA200100517A1 (ru)	2001-12-24
WO2000039128A1 (en)	2000-07-06
KR100417506B1 (ko)	2004-02-05
SK9002001A3 (en)	2002-04-04
CO5150179A1 (es)	2002-04-29
AP2001002188A0 (en)	2001-06-30
CA2356985C (en)	2006-08-08
EP1140931A1 (de)	2001-10-10
NZ511964A (en)	2003-08-29
AU761711B2 (en)	2003-06-05
EA003099B1 (ru)	2002-12-26
DK1140931T3 (da)	2004-04-19
CN1332740A (zh)	2002-01-23
TR200101979T2 (tr)	2001-12-21
NO20013215D0 (no)	2001-06-27
EP1140931B1 (de)	2004-02-25
UA62015C2 (en)	2003-12-15
ES2214892T3 (es)	2004-09-16
IS5951A (is)	2001-05-22
KR20010092455A (ko)	2001-10-25
CA2356985A1 (en)	2000-07-06
ZA200105041B (en)	2002-06-20
DZ2933A1 (fr)	2004-03-15
TW523514B (en)	2003-03-11
AR024840A1 (es)	2002-10-30
ID30117A (id)	2001-11-08
MA26706A1 (fr)	2004-12-20
JP2002533463A (ja)	2002-10-08
EE200100346A (et)	2002-12-16

Publication	Publication Date	Title
BG106585A (en)	2003-03-31	Kinase inhibitors as therapeutic agents
AU1529402A (en)	2002-05-27	Piperazinylpyrazines compounds as antagonists of serotonin 5-ht2 receptor
BG106013A (en)	2002-05-31	New compounds and compositions as protease inhibitors
BG103485A (en)	2000-01-31	Ketobanzamides as calpain inhibitors
DE60236600D1 (de)	2010-07-15	Substituierte 1h-dihydropyrazole, ihre herstellung und verwendung
MY127144A (en)	2006-11-30	New anticholinergics which may be used as medicaments as well as processes for preparing them
BG106586A (en)	2003-01-31	Pyrazolopyramidines as therapeutic agents
AP2002002637A0 (en)	2002-09-30	Novel piperazine
ATE413388T1 (de)	2008-11-15	Muskarin antagonisten
ES2243579T3 (es)	2005-12-01	Derivados de pirazolopirideno.
AP2001002188A0 (en)	2001-06-30	5HT1 antagonists for antidepressant therapy.
BG106930A (en)	2003-04-30	Substituted phenyl-piperazine derivatives, their preparation and use
SE9901077D0 (sv)	1999-03-23	Novel use
IL140070A0 (en)	2002-02-10	Benzamide derivatives and pharmaceutical compositions containing the same
MXPA05010651A (es)	2005-12-12	Compuestos de pirazol.
MX9700807A (es)	1997-05-31	Derivados de 3-azabiciclo (3.2.0)heptano n-sustituidos utiles como neurolepticos.
DK1204659T3 (da)	2004-04-05	Serotonerge benzofuraner
MXPA05010650A (es)	2005-12-12	Pirazoles sustituidos.
DE502004007387D1 (de)	2008-07-31	Triazolverbindungen und ihre therapeutische verwendung
MX9603199A (es)	1997-07-31	Antagonistas de receptores a endotelina.
ZA983231B (en)	1999-10-18	Substituted benzyloxyimino compounds.
BG105247A (en)	2001-11-30	N-substituted azabicycloheptane derivatives, production and use thereof
MY136138A (en)	2008-08-29	Hexacyclic compounds
ATE265418T1 (de)	2004-05-15	Neue substituierte 3-phenoxy- und 3- phenylalkyloxy-2-phenyl-propylamine
BG105549A (en)	2001-12-29	Use of n-substituted azabicycloalkane derivatives for treating diseases of the central nervous system