BG106190A - Method for the preparation of citalopram - Google Patents

Method for the preparation of citalopram

Info

Publication number: BG106190A
Authority: BG; Bulgaria
Prior art keywords: citalopram; preparation; compound; isolation; reaction
Prior art date: 1999-06-25

Application number

BG106190A

Other languages

Bulgarian (bg)

English (en)

Inventor

Hans Petersen

Michael Rock

Original Assignee

H. Lundbeck A/S

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-06-25

Filing date

2001-12-07

Publication date

2002-08-30

2001-12-07 Application filed by H. Lundbeck A/S filed Critical H. Lundbeck A/S

2002-08-30 Publication of BG106190A publication Critical patent/BG106190A/xx

Links

WSEQXVZVJXJVFP-HXUWFJFHSA-N (R)-citalopram Chemical compound C1([C@@]2(C3=CC=C(C=C3CO2)C#N)CCCN(C)C)=CC=C(F)C=C1 WSEQXVZVJXJVFP-HXUWFJFHSA-N 0.000 title abstract 3
229960001653 citalopram Drugs 0.000 title abstract 3
238000000034 method Methods 0.000 title abstract 2
238000002360 preparation method Methods 0.000 title abstract 2
-1 5-cyano compound Chemical class 0.000 abstract 1
XFXPMWWXUTWYJX-UHFFFAOYSA-N Cyanide Chemical compound N#[C-] XFXPMWWXUTWYJX-UHFFFAOYSA-N 0.000 abstract 1
PXHVJJICTQNCMI-UHFFFAOYSA-N Nickel Chemical compound [Ni] PXHVJJICTQNCMI-UHFFFAOYSA-N 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
238000002955 isolation Methods 0.000 abstract 1

Classifications

- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J31/00—Catalysts comprising hydrides, coordination complexes or organic compounds
- B01J31/16—Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes
- B01J31/22—Organic complexes
- B01J31/2282—Unsaturated compounds used as ligands
- B01J31/2295—Cyclic compounds, e.g. cyclopentadienyls
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J31/00—Catalysts comprising hydrides, coordination complexes or organic compounds
- B01J31/16—Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes
- B01J31/24—Phosphines, i.e. phosphorus bonded to only carbon atoms, or to both carbon and hydrogen atoms, including e.g. sp2-hybridised phosphorus compounds such as phosphabenzene, phosphole or anionic phospholide ligands
- B01J31/2404—Cyclic ligands, including e.g. non-condensed polycyclic ligands, the phosphine-P atom being a ring member or a substituent on the ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2231/00—Catalytic reactions performed with catalysts classified in B01J31/00
- B01J2231/40—Substitution reactions at carbon centres, e.g. C-C or C-X, i.e. carbon-hetero atom, cross-coupling, C-H activation or ring-opening reactions
- B01J2231/42—Catalytic cross-coupling, i.e. connection of previously not connected C-atoms or C- and X-atoms without rearrangement
- B01J2231/4205—C-C cross-coupling, e.g. metal catalyzed or Friedel-Crafts type
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2531/00—Additional information regarding catalytic systems classified in B01J31/00
- B01J2531/80—Complexes comprising metals of Group VIII as the central metal
- B01J2531/84—Metals of the iron group
- B01J2531/847—Nickel

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Inorganic Chemistry (AREA)
Materials Engineering (AREA)
Neurology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Bioinformatics & Cheminformatics (AREA)
Epidemiology (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Hospice & Palliative Care (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Furan Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Steroid Compounds (AREA)

BG106190A 1999-06-25 2001-12-07 Method for the preparation of citalopram BG106190A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DKPA199900921		1999-06-25
PCT/DK1999/000643 WO2000011926A2 (en)	1999-06-25	1999-11-19	Method for the preparation of citalopram

Publications (1)

Publication Number	Publication Date
BG106190A true BG106190A (en)	2002-08-30

Family

ID=8099044

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BG106190A BG106190A (en)	1999-06-25	2001-12-07	Method for the preparation of citalopram

Country Status (36)

Country	Link
US (1)	US6750358B2 (is)
EP (1)	EP1105382B1 (is)
JP (1)	JP3389571B2 (is)
KR (1)	KR100491369B1 (is)
CN (1)	CN1129593C (is)
AR (1)	AR020573A1 (is)
AT (3)	ATE213237T1 (is)
AU (2)	AU1374800A (is)
BG (1)	BG106190A (is)
BR (1)	BR9917367A (is)
CA (1)	CA2290125C (is)
CH (1)	CH691304A5 (is)
CZ (1)	CZ292174B6 (is)
DE (2)	DE19983486C2 (is)
DK (1)	DK1105382T3 (is)
EA (1)	EA002661B1 (is)
ES (1)	ES2172356T3 (is)
FI (1)	FI108538B (is)
GB (1)	GB2354240B (is)
HK (1)	HK1047745B (is)
HU (1)	HUP0103417A3 (is)
IL (1)	IL145960A0 (is)
IS (1)	IS5862A (is)
IT (1)	ITMI991579A1 (is)
MX (1)	MXPA01010986A (is)
NO (1)	NO20010318L (is)
NZ (1)	NZ514982A (is)
PL (1)	PL345971A1 (is)
PT (1)	PT1105382E (is)
SE (1)	SE516689C2 (is)
SI (1)	SI1105382T1 (is)
SK (1)	SK18412001A3 (is)
TR (1)	TR200103700T2 (is)
UA (1)	UA62023C2 (is)
WO (1)	WO2000011926A2 (is)
ZA (1)	ZA200108855B (is)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
TR200101796T2 (tr)	1998-12-23	2001-11-21	H. Lundbeck A/S	5-Siyanofitalitin preparasyonuna yönelik metot
AR022329A1 (es)	1999-01-29	2002-09-04	Lundbeck & Co As H	Metodo para la preparacion de 5-cianoftalida
AU759716B2 (en)	1999-04-14	2003-04-17	H. Lundbeck A/S	Method for the preparation of citalopram
ITMI991581A1 (it) *	1999-06-25	2001-01-15	Lundbeck & Co As H	Metodo per la preparazione di citalopram
ITMI991579A1 (it)	1999-06-25	2001-01-15	Lundbeck & Co As H	Metodo per la preparazione di citalopram
CH692298A5 (de)	1999-10-25	2002-04-30	Lundbeck & Co As H	Verfahren zur Herstellung von Zwischenstufen für die Citalopramsynthese sowie zur Herstellung von Escitalopram.
TR200401456T1 (tr)	1999-10-25	2005-04-21	H. Lundbeck A/S	Sitalopram hazırlanması için yöntem.
AR026063A1 (es)	1999-11-01	2002-12-26	Lundbeck & Co As H	Metodo para la preparacion de 5-carboxiftalida.
EA004742B1 (ru)	1999-12-28	2004-08-26	Х.Лундбекк А/С	Способ получения циталопрама
BR9917604A (pt)	1999-12-30	2002-12-31	Lundbeck & Co As H	Método para preparação de citalopram
HUP0300343A2 (hu)	2000-01-14	2003-06-28	H. Lundbeck A/S	Eljárás 5-cianoftalid előállítására
NL1017415C1 (nl)	2000-02-24	2001-05-18	Lundbeck & Co As H	Werkwijze voor de bereiding van Citalopram.
IES20010157A2 (en)	2000-03-03	2002-03-06	Lundbeck & Co As H	Method for the preparation of citalopram
GB0005477D0 (en)	2000-03-07	2000-04-26	Resolution Chemicals Limited	Process for the preparation of citalopram
GB2357762B (en) *	2000-03-13	2002-01-30	Lundbeck & Co As H	Crystalline base of citalopram
PL360110A1 (en)	2000-03-13	2004-09-06	H.Lundbeck A/S	Method for the preparation of citalopram
CN1427835A (zh) *	2000-03-13	2003-07-02	H·隆德贝克有限公司	5－取代的1－(4－氟苯基)－1,3－二氢异苯并呋喃的分步烷基化
NL1017500C1 (nl)	2000-03-13	2001-04-26	Lundbeck & Co As H	Werkwijze voor de bereiding van Citalopram.
TR200202155T2 (tr)	2000-03-14	2002-12-23	H. Lundbeck A/S	Sitalopramin preparasyon metodu
CZ20023406A3 (cs) *	2000-03-16	2003-01-15	H. Lundbeck A/S	Způsob výroby 5-kyano-1-(4-fluorfenyl)-1,3-dihydroisobenzofuranu
AR032455A1 (es)	2000-05-12	2003-11-12	Lundbeck & Co As H	Metodo para la preparacion de citalopram, un intermediario empleado en el metodo, un metodo para la preparacion del intermediario empleado en el metodo y composicion farmaceutica antidepresiva
CZ2002832A3 (cs) *	2000-07-06	2002-05-15	H. Lundbeck A/S	Způsob výroby citalopramu
CA2354877C (en) *	2000-08-18	2006-05-02	H. Lundbeck A/S	Method for the preparation of citalopram
NL1017525C1 (nl) *	2000-12-22	2001-04-26	Lundbeck & Co As H	Werkwijze voor de bereiding van zuiver Citalopram
ATE222899T1 (de) *	2000-12-28	2002-09-15	Lundbeck & Co As H	Verfahren zur herstellung von reinem citalopram
EP1355897A1 (en)	2001-01-30	2003-10-29	Orion Corporation Fermion	Process for the preparation of 1-(3-dimethylaminopropyl)-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile
GB0105627D0 (en) *	2001-03-07	2001-04-25	Cipla Ltd	Preparation of phthalanes
WO2002072565A1 (en) *	2001-03-09	2002-09-19	Ranbaxy Laboratories Limited	Process for the preparation of citalopram
BR0206164A (pt)	2001-07-31	2003-10-28	Lundbeck & Co As H	Partìculas cristalinas de oxalato de escitalopram, método para a produção de partìculas cristalinas de oxalato de escitalopram, e, forma de dosagem unitária sólida
AU2003222435A1 (en)	2002-01-07	2003-07-24	Sun Pharmaceutical Industries Limited	Process for the preparation of 1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)- 1,3-dihydro-5-isobenzofuran carbonitrile
AR040970A1 (es)	2002-08-12	2005-04-27	Lundbeck & Co As H	Metodo para la separacion de intermediarios que pueden ser utilizados para la preparacion de escitalopram
US20050154052A1 (en) *	2003-03-24	2005-07-14	Hetero Drugs Limited	Novel crystalline forms of (s)-citalopram oxalate
US7019153B2 (en)	2003-06-10	2006-03-28	Sun Pharmaceutical Industries Limited	Process for hydrogenolysis of [1-(3-dimethylamino)propyl)]-1-(4-fluorophenyl)-1,3-dihydro-5-halo-isobenzofuran acetamido-3-substituted-3-cephem-4-carboxylic acid
TWI339651B (en)	2004-02-12	2011-04-01	Lundbeck & Co As H	Method for the separation of intermediates which may be used for the preparation of escitalopram
JP2006008603A (ja) *	2004-06-25	2006-01-12	Sumitomo Chemical Co Ltd	光学活性シタロプラムの製造方法、その中間体およびその製造方法
US7790935B2 (en)	2004-08-23	2010-09-07	Sun Pharma Global Fze	Process for preparation of citalopram and enantiomers
WO2006103550A1 (en) *	2005-03-31	2006-10-05	Ranbaxy Laboratories Limited	Processes for the preparation of citalopram and its intermediate 5-aminophthalide
TWI358407B (en)	2005-06-22	2012-02-21	Lundbeck & Co As H	Crystalline base of escitalopram and orodispersibl
US7834201B2 (en)	2005-06-22	2010-11-16	H. Lundbeck A/S	Crystalline base of escitalopram and orodispersible tablets comprising escitalopram base
EP2017271A1 (en)	2007-07-06	2009-01-21	Aurobindo Pharma Limited	Process for the preparation of escitalopram

Family Cites Families (24)

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Publication number	Priority date	Publication date	Assignee	Title
GB1143702A (is)	1965-03-18
GB1526331A (en) *	1976-01-14	1978-09-27	Kefalas As	Phthalanes
GB8419963D0 (en)	1984-08-06	1984-09-12	Lundbeck & Co As H	Intermediate compound and method
GB8814057D0 (en)	1988-06-14	1988-07-20	Lundbeck & Co As H	New enantiomers & their isolation
CA2010159A1 (en)	1989-02-21	1990-08-21	James J. Maul	Cyanation of haloaromatics utilizing catalysts generated in situ starting with nic1 or nic1 6h 0
US5296507A (en)	1990-09-06	1994-03-22	H.Lundbeck A/S	Treatment of cerbrovascular disorders
DE19626659A1 (de)	1996-07-03	1998-01-08	Basf Ag	Verfahren zur Herstellung von Phthaliden
DE19627697A1 (de)	1996-07-10	1998-01-15	Basf Ag	Verfahren zur Herstellung von Phthaliden
DE19706648A1 (de)	1997-02-20	1998-08-27	Bayer Ag	Verfahren zur Herstellung von aromatischen Nitrilen
WO1998019513A2 (en)	1997-07-08	1998-05-14	H. Lundbeck A/S	Method for the preparation of citalopram
UA62985C2 (en)	1997-11-10	2004-01-15	Lunnbeck As H	A method for the preparation of citalopram
EP1042310B1 (en)	1997-11-11	2002-07-31	H. Lundbeck A/S	Method for the preparation of citalopram
CA2291134C (en)	1998-10-20	2006-05-23	H. Lundbeck A/S	Method for the preparation of citalopram
TR200101796T2 (tr)	1998-12-23	2001-11-21	H. Lundbeck A/S	5-Siyanofitalitin preparasyonuna yönelik metot
AR022329A1 (es)	1999-01-29	2002-09-04	Lundbeck & Co As H	Metodo para la preparacion de 5-cianoftalida
US6331628B1 (en)	1999-03-29	2001-12-18	Nissan Chemical Industries, Ltd.	Process for the preparation of benzonitrile compounds
AU759716B2 (en)	1999-04-14	2003-04-17	H. Lundbeck A/S	Method for the preparation of citalopram
ITMI991581A1 (it)	1999-06-25	2001-01-15	Lundbeck & Co As H	Metodo per la preparazione di citalopram
ITMI991579A1 (it)	1999-06-25	2001-01-15	Lundbeck & Co As H	Metodo per la preparazione di citalopram
CH692298A5 (de)	1999-10-25	2002-04-30	Lundbeck & Co As H	Verfahren zur Herstellung von Zwischenstufen für die Citalopramsynthese sowie zur Herstellung von Escitalopram.
US6310222B1 (en)	1999-11-01	2001-10-30	Sumika Fine Chemicals Co., Ltd.	Production method of 5-phthalancarbonitrile compound, intermediate therefor and production method of the intermediate
GB0005477D0 (en)	2000-03-07	2000-04-26	Resolution Chemicals Limited	Process for the preparation of citalopram
NL1017525C1 (nl)	2000-12-22	2001-04-26	Lundbeck & Co As H	Werkwijze voor de bereiding van zuiver Citalopram
ATE222899T1 (de)	2000-12-28	2002-09-15	Lundbeck & Co As H	Verfahren zur herstellung von reinem citalopram

1999
- 1999-07-15 IT IT1999MI001579A patent/ITMI991579A1/it unknown
- 1999-11-19 AT AT99968206T patent/ATE213237T1/de not_active IP Right Cessation
- 1999-11-19 UA UA2001117897A patent/UA62023C2/uk unknown
- 1999-11-19 PL PL99345971A patent/PL345971A1/xx not_active Application Discontinuation
- 1999-11-19 AT AT0904099A patent/AT409960B/de not_active IP Right Cessation
- 1999-11-19 AU AU13748/00A patent/AU1374800A/en active Pending
- 1999-11-19 CN CN99816768A patent/CN1129593C/zh not_active Expired - Fee Related
- 1999-11-19 GB GB0101508A patent/GB2354240B/en not_active Expired - Fee Related
- 1999-11-19 DE DE19983486T patent/DE19983486C2/de not_active Expired - Fee Related
- 1999-11-19 DE DE69900891T patent/DE69900891D1/de not_active Expired - Lifetime
- 1999-11-19 SK SK1841-2001A patent/SK18412001A3/sk unknown
- 1999-11-19 TR TR2001/03700T patent/TR200103700T2/xx unknown
- 1999-11-19 HU HU0103417A patent/HUP0103417A3/hu unknown
- 1999-11-19 SI SI9930039T patent/SI1105382T1/xx unknown
- 1999-11-19 BR BR9917367-0A patent/BR9917367A/pt not_active IP Right Cessation
- 1999-11-19 PT PT99968206T patent/PT1105382E/pt unknown
- 1999-11-19 NZ NZ514982A patent/NZ514982A/xx unknown
- 1999-11-19 KR KR10-2001-7013971A patent/KR100491369B1/ko not_active Expired - Fee Related
- 1999-11-19 DK DK99968206T patent/DK1105382T3/da active
- 1999-11-19 MX MXPA01010986A patent/MXPA01010986A/es not_active IP Right Cessation
- 1999-11-19 CZ CZ2001319A patent/CZ292174B6/cs not_active IP Right Cessation
- 1999-11-19 EP EP99968206A patent/EP1105382B1/en not_active Expired - Lifetime
- 1999-11-19 CH CH00307/01A patent/CH691304A5/de not_active IP Right Cessation
- 1999-11-19 HK HK02109330.8A patent/HK1047745B/zh not_active IP Right Cessation
- 1999-11-19 EA EA200101071A patent/EA002661B1/ru not_active IP Right Cessation
- 1999-11-19 ES ES99968206T patent/ES2172356T3/es not_active Expired - Lifetime
- 1999-11-19 JP JP2000567065A patent/JP3389571B2/ja not_active Expired - Fee Related
- 1999-11-19 WO PCT/DK1999/000643 patent/WO2000011926A2/en not_active Ceased
- 1999-11-19 IL IL14596099A patent/IL145960A0/xx unknown
- 1999-11-19 AU AU2001100433A patent/AU2001100433B4/en not_active Ceased
- 1999-11-22 CA CA002290125A patent/CA2290125C/en not_active Expired - Fee Related
2000
- 2000-06-21 AR ARP000103080A patent/AR020573A1/es unknown
2001
- 2001-01-19 NO NO20010318A patent/NO20010318L/no unknown
- 2001-01-24 SE SE0100194A patent/SE516689C2/sv not_active IP Right Cessation
- 2001-01-25 FI FI20010154A patent/FI108538B/fi not_active IP Right Cessation
- 2001-02-23 IS IS5862A patent/IS5862A/is unknown
- 2001-03-13 AT AT0018501U patent/AT4366U1/de not_active IP Right Cessation
- 2001-10-26 ZA ZA200108855A patent/ZA200108855B/xx unknown
- 2001-11-06 US US10/012,025 patent/US6750358B2/en not_active Expired - Fee Related
- 2001-12-07 BG BG106190A patent/BG106190A/xx unknown

Also Published As

Publication number	Publication date
CZ292174B6 (cs)	2003-08-13
EA002661B1 (ru)	2002-08-29
CN1356993A (zh)	2002-07-03
AU2001100433B4 (en)	2002-01-17
PT1105382E (pt)	2002-07-31
NZ514982A (en)	2004-01-30
SE516689C2 (sv)	2002-02-12
IL145960A0 (en)	2002-07-25
AU1374800A (en)	2000-03-21
SI1105382T1 (en)	2002-06-30
ATA904099A (de)	2002-05-15
SK18412001A3 (sk)	2002-05-09
ITMI991579A1 (it)	2001-01-15
FI108538B (fi)	2002-02-15
AR020573A1 (es)	2002-05-15
EP1105382B1 (en)	2002-02-13
CN1129593C (zh)	2003-12-03
CZ2001319A3 (en)	2001-05-16
NO20010318L (no)	2001-02-20
SE0100194D0 (sv)	2001-01-24
US20020061925A1 (en)	2002-05-23
DE19983486C2 (de)	2002-09-05
BR9917367A (pt)	2002-03-05
ES2172356T3 (es)	2002-09-16
UA62023C2 (en)	2003-12-15
US6750358B2 (en)	2004-06-15
WO2000011926A3 (en)	2000-06-29
SE0100194L (sv)	2001-04-25
AU2001100433A4 (en)	2001-11-01
GB2354240A (en)	2001-03-21
HUP0103417A3 (en)	2003-01-28
ATE213237T1 (de)	2002-02-15
EA200101071A1 (ru)	2002-02-28
CA2290125C (en)	2004-08-10
NO20010318D0 (no)	2001-01-19
EP1105382A2 (en)	2001-06-13
HK1047745B (zh)	2004-09-10
KR20020011982A (ko)	2002-02-09
AT4366U1 (de)	2001-06-25
CH691304A5 (de)	2001-06-29
JP3389571B2 (ja)	2003-03-24
DE19983486T1 (de)	2001-10-18
TR200103700T2 (tr)	2002-05-21
IS5862A (is)	2001-02-23
KR100491369B1 (ko)	2005-05-24
WO2000011926A2 (en)	2000-03-09
GB2354240B (en)	2001-05-23
JP2002523432A (ja)	2002-07-30
MXPA01010986A (es)	2002-06-04
GB0101508D0 (en)	2001-03-07
PL345971A1 (en)	2002-01-14
ZA200108855B (en)	2002-08-28
AT409960B (de)	2002-12-27
DK1105382T3 (da)	2002-05-27
CA2290125A1 (en)	2000-12-25
DE69900891D1 (de)	2002-03-21
ITMI991579A0 (it)	1999-07-15
HK1047745A1 (en)	2003-03-07
FI20010154L (fi)	2001-02-09
HUP0103417A2 (hu)	2002-01-28

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