ATA904099A - Verfahren zur herstellung von citalopram - Google Patents

Verfahren zur herstellung von citalopram

Info

Publication number: ATA904099A
Authority: AT; Austria
Prior art keywords: producing citalopram; citalopram; producing
Prior art date: 1999-06-25

Application number

AT0904099A

Other languages

English (en)

Other versions

AT409960B (de

Original Assignee

Lundbeck & Co As H

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-06-25

Filing date

1999-11-19

Publication date

2002-05-15

1999-11-19 Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H

2002-05-15 Publication of ATA904099A publication Critical patent/ATA904099A/de

2002-12-27 Application granted granted Critical

2002-12-27 Publication of AT409960B publication Critical patent/AT409960B/de

Links

WSEQXVZVJXJVFP-UHFFFAOYSA-N 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile Chemical compound O1CC2=CC(C#N)=CC=C2C1(CCCN(C)C)C1=CC=C(F)C=C1 WSEQXVZVJXJVFP-UHFFFAOYSA-N 0.000 title 1
229960001653 citalopram Drugs 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1

Classifications

- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J31/00—Catalysts comprising hydrides, coordination complexes or organic compounds
- B01J31/16—Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes
- B01J31/22—Organic complexes
- B01J31/2282—Unsaturated compounds used as ligands
- B01J31/2295—Cyclic compounds, e.g. cyclopentadienyls
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J31/00—Catalysts comprising hydrides, coordination complexes or organic compounds
- B01J31/16—Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes
- B01J31/24—Phosphines, i.e. phosphorus bonded to only carbon atoms, or to both carbon and hydrogen atoms, including e.g. sp2-hybridised phosphorus compounds such as phosphabenzene, phosphole or anionic phospholide ligands
- B01J31/2404—Cyclic ligands, including e.g. non-condensed polycyclic ligands, the phosphine-P atom being a ring member or a substituent on the ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2231/00—Catalytic reactions performed with catalysts classified in B01J31/00
- B01J2231/40—Substitution reactions at carbon centres, e.g. C-C or C-X, i.e. carbon-hetero atom, cross-coupling, C-H activation or ring-opening reactions
- B01J2231/42—Catalytic cross-coupling, i.e. connection of previously not connected C-atoms or C- and X-atoms without rearrangement
- B01J2231/4205—C-C cross-coupling, e.g. metal catalyzed or Friedel-Crafts type
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2531/00—Additional information regarding catalytic systems classified in B01J31/00
- B01J2531/80—Complexes comprising metals of Group VIII as the central metal
- B01J2531/84—Metals of the iron group
- B01J2531/847—Nickel

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Materials Engineering (AREA)
Inorganic Chemistry (AREA)
Biomedical Technology (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Epidemiology (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Hospice & Palliative Care (AREA)
Rheumatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Steroid Compounds (AREA)
Furan Compounds (AREA)

AT0904099A 1999-06-25 1999-11-19 Verfahren zur herstellung von citalopram AT409960B (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DKPA199900921		1999-06-25
PCT/DK1999/000643 WO2000011926A2 (en)	1999-06-25	1999-11-19	Method for the preparation of citalopram

Publications (2)

Publication Number	Publication Date
ATA904099A true ATA904099A (de)	2002-05-15
AT409960B AT409960B (de)	2002-12-27

Family

ID=8099044

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
AT0904099A AT409960B (de)	1999-06-25	1999-11-19	Verfahren zur herstellung von citalopram
AT99968206T ATE213237T1 (de)	1999-06-25	1999-11-19	Verfahren zur herstellung von citalopram
AT0018501U AT4366U1 (de)	1999-06-25	2001-03-13	Verfahren zur herstellung von citalopram

Family Applications After (2)

Application Number	Title	Priority Date	Filing Date
AT99968206T ATE213237T1 (de)	1999-06-25	1999-11-19	Verfahren zur herstellung von citalopram
AT0018501U AT4366U1 (de)	1999-06-25	2001-03-13	Verfahren zur herstellung von citalopram

Country Status (36)

Country	Link
US (1)	US6750358B2 (de)
EP (1)	EP1105382B1 (de)
JP (1)	JP3389571B2 (de)
KR (1)	KR100491369B1 (de)
CN (1)	CN1129593C (de)
AR (1)	AR020573A1 (de)
AT (3)	AT409960B (de)
AU (2)	AU1374800A (de)
BG (1)	BG106190A (de)
BR (1)	BR9917367A (de)
CA (1)	CA2290125C (de)
CH (1)	CH691304A5 (de)
CZ (1)	CZ292174B6 (de)
DE (2)	DE69900891D1 (de)
DK (1)	DK1105382T3 (de)
EA (1)	EA002661B1 (de)
ES (1)	ES2172356T3 (de)
FI (1)	FI108538B (de)
GB (1)	GB2354240B (de)
HK (1)	HK1047745B (de)
HU (1)	HUP0103417A3 (de)
IL (1)	IL145960A0 (de)
IS (1)	IS5862A (de)
IT (1)	ITMI991579A1 (de)
MX (1)	MXPA01010986A (de)
NO (1)	NO20010318L (de)
NZ (1)	NZ514982A (de)
PL (1)	PL345971A1 (de)
PT (1)	PT1105382E (de)
SE (1)	SE516689C2 (de)
SI (1)	SI1105382T1 (de)
SK (1)	SK18412001A3 (de)
TR (1)	TR200103700T2 (de)
UA (1)	UA62023C2 (de)
WO (1)	WO2000011926A2 (de)
ZA (1)	ZA200108855B (de)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
HK1043130B (zh)	1998-12-23	2005-03-04	H‧隆德贝克有限公司	制备5-氰基2-苯并[c]呋喃酮的方法
AR022329A1 (es)	1999-01-29	2002-09-04	Lundbeck & Co As H	Metodo para la preparacion de 5-cianoftalida
IL145615A0 (en)	1999-04-14	2002-06-30	Lundbeck & Co As H	Method for the preparation of citalopram
ITMI991581A1 (it) *	1999-06-25	2001-01-15	Lundbeck & Co As H	Metodo per la preparazione di citalopram
ITMI991579A1 (it)	1999-06-25	2001-01-15	Lundbeck & Co As H	Metodo per la preparazione di citalopram
GB2360281B (en)	1999-10-25	2002-01-16	Lundbeck & Co As H	Method for the preparation of citalopram
HK1043129B (zh)	1999-10-25	2004-10-21	H‧隆德贝克有限公司	西酞普蘭的製備方法
AR026063A1 (es)	1999-11-01	2002-12-26	Lundbeck & Co As H	Metodo para la preparacion de 5-carboxiftalida.
NZ519739A (en)	1999-12-28	2004-03-26	H	Method for the preparation of citalopram
PT1246813E (pt)	1999-12-30	2004-02-27	Lundbeck & Co As H	Metodo para a preparacao de citalopram
WO2001051477A1 (en)	2000-01-14	2001-07-19	H. Lundbeck A/S	Method for the preparation of 5-cyanophthalide
NL1017415C1 (nl)	2000-02-24	2001-05-18	Lundbeck & Co As H	Werkwijze voor de bereiding van Citalopram.
IES20010157A2 (en)	2000-03-03	2002-03-06	Lundbeck & Co As H	Method for the preparation of citalopram
GB0005477D0 (en)	2000-03-07	2000-04-26	Resolution Chemicals Limited	Process for the preparation of citalopram
BR0109364A (pt)	2000-03-13	2002-12-24	Lundbeck & Co As H	Métodos para fabricação de citalopram através de alquilação escalonada de 5-substituìda 1- (4-fluorofenil) - 1,3- diidroisobenzofuranos e citalopram
GB2357762B (en) *	2000-03-13	2002-01-30	Lundbeck & Co As H	Crystalline base of citalopram
NL1017500C1 (nl)	2000-03-13	2001-04-26	Lundbeck & Co As H	Werkwijze voor de bereiding van Citalopram.
SK14602002A3 (sk)	2000-03-13	2003-02-04	H. Lundbeck A/S	Spôsob výroby citalopramu a medziprodukty
IL151488A0 (en)	2000-03-14	2003-04-10	Lundbeck & Co As H	Method for the preparation of citalopram
TR200202168T2 (tr) *	2000-03-16	2002-12-23	H. Lundbeck A/S	5-Siyano-1-(4-Florofenil)-1,3-Dihidroizobenzofuranların preparasyon metodu
AR032455A1 (es)	2000-05-12	2003-11-12	Lundbeck & Co As H	Metodo para la preparacion de citalopram, un intermediario empleado en el metodo, un metodo para la preparacion del intermediario empleado en el metodo y composicion farmaceutica antidepresiva
SK3362002A3 (en) *	2000-07-06	2002-08-06	Lundbeck & Co As H	Method for the preparation of citalopram
IL144816A (en) *	2000-08-18	2005-09-25	Lundbeck & Co As H	Method for the preparation of citalopram
TR200201166T1 (tr) *	2000-12-22	2002-10-21	H.Lundbecks A/S	Saf sitalopram hazırlanması için yöntem
JP2003519121A (ja) *	2000-12-28	2003-06-17	ハー・ルンドベック・アクチエゼルスカベット	純粋なシタロプラムの製造方法
CA2435925A1 (en)	2001-01-30	2002-08-08	Orion Corporation Fermion	Process for the preparation of 1-(3-dimethylaminopropyl)-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile
GB0105627D0 (en) *	2001-03-07	2001-04-25	Cipla Ltd	Preparation of phthalanes
HRP20030811A2 (en) *	2001-03-09	2005-08-31	Ranbaxy Laboratories Limited	Process for the preparation of citalopram
ATE352546T1 (de) *	2001-07-31	2007-02-15	Lundbeck & Co As H	Kristalline zusammensetzung enthaltend escitalopram
WO2003057132A2 (en)	2002-01-07	2003-07-17	Sun Pharmaceutical Industries Limited	Process for the preparation of 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)- 1,3-dihydro-5-isobenzofuran carbonitrile
AR040970A1 (es)	2002-08-12	2005-04-27	Lundbeck & Co As H	Metodo para la separacion de intermediarios que pueden ser utilizados para la preparacion de escitalopram
AU2003223105A1 (en) *	2003-03-24	2004-10-18	Hetero Drugs Limited	Novel crystalline forms of (s)-citalopram oxalate
EP1486492A3 (de) *	2003-06-10	2005-02-23	Sun Pharmaceuticals Industries Ltd.	Ein Verfahren zur Hydrogenolyse von [1-(3-dimethylamino)propyl)]-1-(4-fluorophenyl)-1,3-dihydro-5-halo-isobenzofuran
TWI339651B (en)	2004-02-12	2011-04-01	Lundbeck & Co As H	Method for the separation of intermediates which may be used for the preparation of escitalopram
JP2006008603A (ja) *	2004-06-25	2006-01-12	Sumitomo Chemical Co Ltd	光学活性シタロプラムの製造方法、その中間体およびその製造方法
KR101166280B1 (ko)	2004-08-23	2013-11-27	썬 파마 글로벌 에프제트이	시탈로프램 및 에난티오머의 제조 방법
WO2006103550A1 (en) *	2005-03-31	2006-10-05	Ranbaxy Laboratories Limited	Processes for the preparation of citalopram and its intermediate 5-aminophthalide
TWI358407B (en)	2005-06-22	2012-02-21	Lundbeck & Co As H	Crystalline base of escitalopram and orodispersibl
US7834201B2 (en)	2005-06-22	2010-11-16	H. Lundbeck A/S	Crystalline base of escitalopram and orodispersible tablets comprising escitalopram base
EP2017271A1 (de)	2007-07-06	2009-01-21	Aurobindo Pharma Limited	Verfahren zur Herstellung von Escitalopram

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1143703A (de)	1965-03-18
GB1526331A (en) *	1976-01-14	1978-09-27	Kefalas As	Phthalanes
GB8419963D0 (en)	1984-08-06	1984-09-12	Lundbeck & Co As H	Intermediate compound and method
GB8814057D0 (en)	1988-06-14	1988-07-20	Lundbeck & Co As H	New enantiomers & their isolation
CA2010159A1 (en)	1989-02-21	1990-08-21	James J. Maul	Cyanation of haloaromatics utilizing catalysts generated in situ starting with nic1 or nic1 6h 0
US5296507A (en)	1990-09-06	1994-03-22	H.Lundbeck A/S	Treatment of cerbrovascular disorders
DE19626659A1 (de)	1996-07-03	1998-01-08	Basf Ag	Verfahren zur Herstellung von Phthaliden
DE19627697A1 (de)	1996-07-10	1998-01-15	Basf Ag	Verfahren zur Herstellung von Phthaliden
DE19706648A1 (de)	1997-02-20	1998-08-27	Bayer Ag	Verfahren zur Herstellung von aromatischen Nitrilen
JP3526581B2 (ja)	1997-07-08	2004-05-17	ハー・ルンドベック・アクティーゼルスカブ	シタロプラムの製造方法
UA62985C2 (en)	1997-11-10	2004-01-15	Lunnbeck As H	A method for the preparation of citalopram
CN1286687A (zh)	1997-11-11	2001-03-07	H·隆德贝克有限公司	制备西酞普兰的方法
WO2000023431A1 (en)	1998-10-20	2000-04-27	H. Lundbeck A/S	Method for the preparation of citalopram
HK1043130B (zh)	1998-12-23	2005-03-04	H‧隆德贝克有限公司	制备5-氰基2-苯并[c]呋喃酮的方法
AR022329A1 (es)	1999-01-29	2002-09-04	Lundbeck & Co As H	Metodo para la preparacion de 5-cianoftalida
DE10015280A1 (de)	1999-03-29	2001-01-04	Nissan Chemical Ind Ltd	Verfahren zur Herstellung von Benzonitrilverbindungen
IL145615A0 (en)	1999-04-14	2002-06-30	Lundbeck & Co As H	Method for the preparation of citalopram
ITMI991579A1 (it)	1999-06-25	2001-01-15	Lundbeck & Co As H	Metodo per la preparazione di citalopram
ITMI991581A1 (it)	1999-06-25	2001-01-15	Lundbeck & Co As H	Metodo per la preparazione di citalopram
GB2360281B (en)	1999-10-25	2002-01-16	Lundbeck & Co As H	Method for the preparation of citalopram
US6310222B1 (en)	1999-11-01	2001-10-30	Sumika Fine Chemicals Co., Ltd.	Production method of 5-phthalancarbonitrile compound, intermediate therefor and production method of the intermediate
GB0005477D0 (en)	2000-03-07	2000-04-26	Resolution Chemicals Limited	Process for the preparation of citalopram
TR200201166T1 (tr)	2000-12-22	2002-10-21	H.Lundbecks A/S	Saf sitalopram hazırlanması için yöntem
JP2003519121A (ja)	2000-12-28	2003-06-17	ハー・ルンドベック・アクチエゼルスカベット	純粋なシタロプラムの製造方法

1999
- 1999-07-15 IT IT1999MI001579A patent/ITMI991579A1/it unknown
- 1999-11-19 WO PCT/DK1999/000643 patent/WO2000011926A2/en not_active Ceased
- 1999-11-19 AU AU13748/00A patent/AU1374800A/en active Pending
- 1999-11-19 DE DE69900891T patent/DE69900891D1/de not_active Expired - Lifetime
- 1999-11-19 AU AU2001100433A patent/AU2001100433B4/en not_active Ceased
- 1999-11-19 BR BR9917367-0A patent/BR9917367A/pt not_active IP Right Cessation
- 1999-11-19 MX MXPA01010986A patent/MXPA01010986A/es not_active IP Right Cessation
- 1999-11-19 JP JP2000567065A patent/JP3389571B2/ja not_active Expired - Fee Related
- 1999-11-19 EP EP99968206A patent/EP1105382B1/de not_active Expired - Lifetime
- 1999-11-19 AT AT0904099A patent/AT409960B/de not_active IP Right Cessation
- 1999-11-19 EA EA200101071A patent/EA002661B1/ru not_active IP Right Cessation
- 1999-11-19 SI SI9930039T patent/SI1105382T1/xx unknown
- 1999-11-19 SK SK1841-2001A patent/SK18412001A3/sk unknown
- 1999-11-19 CZ CZ2001319A patent/CZ292174B6/cs not_active IP Right Cessation
- 1999-11-19 DK DK99968206T patent/DK1105382T3/da active
- 1999-11-19 PL PL99345971A patent/PL345971A1/xx not_active Application Discontinuation
- 1999-11-19 HU HU0103417A patent/HUP0103417A3/hu unknown
- 1999-11-19 AT AT99968206T patent/ATE213237T1/de not_active IP Right Cessation
- 1999-11-19 IL IL14596099A patent/IL145960A0/xx unknown
- 1999-11-19 ES ES99968206T patent/ES2172356T3/es not_active Expired - Lifetime
- 1999-11-19 PT PT99968206T patent/PT1105382E/pt unknown
- 1999-11-19 HK HK02109330.8A patent/HK1047745B/zh not_active IP Right Cessation
- 1999-11-19 TR TR2001/03700T patent/TR200103700T2/xx unknown
- 1999-11-19 KR KR10-2001-7013971A patent/KR100491369B1/ko not_active Expired - Fee Related
- 1999-11-19 GB GB0101508A patent/GB2354240B/en not_active Expired - Fee Related
- 1999-11-19 NZ NZ514982A patent/NZ514982A/xx unknown
- 1999-11-19 CN CN99816768A patent/CN1129593C/zh not_active Expired - Fee Related
- 1999-11-19 CH CH00307/01A patent/CH691304A5/de not_active IP Right Cessation
- 1999-11-19 UA UA2001117897A patent/UA62023C2/uk unknown
- 1999-11-19 DE DE19983486T patent/DE19983486C2/de not_active Expired - Fee Related
- 1999-11-22 CA CA002290125A patent/CA2290125C/en not_active Expired - Fee Related
2000
- 2000-06-21 AR ARP000103080A patent/AR020573A1/es unknown
2001
- 2001-01-19 NO NO20010318A patent/NO20010318L/no unknown
- 2001-01-24 SE SE0100194A patent/SE516689C2/sv not_active IP Right Cessation
- 2001-01-25 FI FI20010154A patent/FI108538B/fi not_active IP Right Cessation
- 2001-02-23 IS IS5862A patent/IS5862A/is unknown
- 2001-03-13 AT AT0018501U patent/AT4366U1/de not_active IP Right Cessation
- 2001-10-26 ZA ZA200108855A patent/ZA200108855B/xx unknown
- 2001-11-06 US US10/012,025 patent/US6750358B2/en not_active Expired - Fee Related
- 2001-12-07 BG BG106190A patent/BG106190A/xx unknown

Also Published As

Publication number	Publication date
FI20010154L (fi)	2001-02-09
SI1105382T1 (en)	2002-06-30
AU1374800A (en)	2000-03-21
ATE213237T1 (de)	2002-02-15
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Legal Events

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Publication	Publication Date	Title
ATE237604T1 (de)	2003-05-15	Verfahren zur herstellung von citalopram
DE69900891D1 (de)	2002-03-21	Verfahren zur herstellung von citalopram
ATE235478T1 (de)	2003-04-15	Verfahren zur herstellung von citalopram
ATE230738T1 (de)	2003-01-15	Verfahren zur herstellung von citalopram
ATE363476T1 (de)	2007-06-15	Verfahren zur herstellung von furfural
ATE232524T1 (de)	2003-02-15	Verfahren zur herstellung von citalopram
ATE222900T1 (de)	2002-09-15	Verfahren zur herstellung von 5-cyanophthalid
ATE281448T1 (de)	2004-11-15	Verfahren zur herstellung von citalopram
DE60100016D1 (de)	2002-10-02	Verfahren zur herstellung von reinem citalopram
ATE236145T1 (de)	2003-04-15	Verfahren zur herstellung von 5-cyanophthalid
DE69908824D1 (de)	2003-07-17	Verfahren zur herstellung von bisphenol-a
DE60003264D1 (de)	2003-07-17	Verfahren zur herstellung von glycerylethern
ATE389645T1 (de)	2008-04-15	Verfahren zur herstellung von citalopram
DE50006772D1 (de)	2004-07-15	Verfahren zur herstellung von oxindolen
DE59901552D1 (de)	2002-07-04	Verfahren zur herstellung von polyalkylenarylaten
ATE355268T1 (de)	2006-03-15	Verfahren zur herstellung von citalopram
EP1208106A4 (de)	2003-01-02	Verfahren zur herstellung von aminopropyl- oder aminoalkyl-unktionalisierten polyalkyl- oder aryl-siloxanen
DE60107061D1 (de)	2004-12-16	Verfahren zur herstellung von citalopram
DE50001895D1 (de)	2003-05-28	Verfahren zur herstellung von phosphonomethylglycin
DE60004834D1 (de)	2003-10-02	Verfahren zur herstellung von mikrokapseln
ATE233238T1 (de)	2003-03-15	Verfahren zur herstellung von 3-acyl-indolen
DE50002773D1 (de)	2003-08-07	Verfahren zur herstellung von hydroxymethylpyridinen
DE60011427D1 (de)	2004-07-15	Verfahren zur herstellung von 2-pyridylpiperidin-derivaten
DE50004440D1 (de)	2003-12-18	Verfahren zur herstellung von phosphonomethylglycin
DE60009060D1 (de)	2004-04-22	Verfahren zur herstellung von 2-pyridylpyridin-derivaten