BG60647B1 - Инденоиндолови съединения - Google Patents

Инденоиндолови съединения Download PDF

Info

Publication number
BG60647B1
BG60647B1 BG95666A BG9566691A BG60647B1 BG 60647 B1 BG60647 B1 BG 60647B1 BG 95666 A BG95666 A BG 95666A BG 9566691 A BG9566691 A BG 9566691A BG 60647 B1 BG60647 B1 BG 60647B1
Authority
BG
Bulgaria
Prior art keywords
group
lower alkyl
hydrogen
formula
alkyl group
Prior art date
Application number
BG95666A
Other languages
Bulgarian (bg)
English (en)
Inventor
Malcolm Sainsbury
Howard G Shertzer
Original Assignee
Univ Bath
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Bath filed Critical Univ Bath
Publication of BG60647B1 publication Critical patent/BG60647B1/bg

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/94—[b, c]- or [b, d]-condensed containing carbocyclic rings other than six-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/58—[b]- or [c]-condensed
    • C07D209/70—[b]- or [c]-condensed containing carbocyclic rings other than six-membered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Hospice & Palliative Care (AREA)
  • Diabetes (AREA)
  • Vascular Medicine (AREA)
  • Psychiatry (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Anti-Oxidant Or Stabilizer Compositions (AREA)
BG95666A 1989-06-22 1991-12-20 Инденоиндолови съединения BG60647B1 (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE8902273A SE8902273D0 (sv) 1989-06-22 1989-06-22 Indenoindole compounds i
PCT/GB1990/000948 WO1990015800A1 (en) 1989-06-22 1990-06-20 Indenoindole compounds

Publications (1)

Publication Number Publication Date
BG60647B1 true BG60647B1 (bg) 1995-11-30

Family

ID=20376369

Family Applications (1)

Application Number Title Priority Date Filing Date
BG95666A BG60647B1 (bg) 1989-06-22 1991-12-20 Инденоиндолови съединения

Country Status (27)

Country Link
US (1) US5185360A (is)
EP (1) EP0404536A1 (is)
JP (1) JPH04506515A (is)
KR (1) KR920702680A (is)
CN (1) CN1049156A (is)
AU (1) AU644082B2 (is)
BG (1) BG60647B1 (is)
CA (1) CA2062830A1 (is)
DD (1) DD298388A5 (is)
FI (1) FI915998A7 (is)
HR (1) HRP920897A2 (is)
HU (1) HUT59096A (is)
IE (1) IE902246A1 (is)
IL (1) IL94829A0 (is)
IS (1) IS3589A7 (is)
JO (2) JO1622B1 (is)
LT (1) LTIP911A (is)
MX (1) MX21243A (is)
NO (1) NO915050L (is)
NZ (1) NZ234174A (is)
PL (1) PL166155B1 (is)
PT (1) PT94467A (is)
SE (1) SE8902273D0 (is)
TW (1) TW198025B (is)
WO (1) WO1990015800A1 (is)
YU (1) YU122290A (is)
ZA (1) ZA904826B (is)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9202736D0 (sv) * 1992-09-22 1992-09-22 Asea Brown Boveri Elektrisk ledare med isolering
SE9302431D0 (sv) * 1993-07-16 1993-07-16 Ab Astra Use of indenoindole compounds
CA2128283A1 (fr) * 1993-07-20 1995-01-21 Paul Caubere (thia)cycloalkyl¬b|indoles, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2720064B1 (fr) * 1994-05-19 1996-06-28 Adir Thiacycloalkyl [b] indoles, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.
US6069153A (en) * 1998-05-12 2000-05-30 American Home Products Corporation Indenoindoles and benzocarbazoles as estrogenic agents
US6288099B1 (en) 1998-12-04 2001-09-11 American Home Products Corporation Substituted benzofuranoindoles and indenoindoles as novel potassium channel openers
CA2350590A1 (en) * 1998-12-04 2000-06-15 John A. Butera Substituted benzofuranoindoles and indenoindoles as novel potassium channel openers
FR2826009B1 (fr) * 2001-06-13 2003-08-15 Servier Lab Nouveaux derives d'indenoindolones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
DE10210623A1 (de) 2002-03-11 2003-09-25 Haarmann & Reimer Gmbh Alkoxy-substituierte Indane und deren Herstellung
MX2008000462A (es) 2005-07-14 2008-03-10 Irm Llc Compuestos heterotetraciclicos como mimeticos de tpo.
CN105745301B (zh) * 2013-11-20 2020-04-21 东进世美肯株式会社 新型发光化合物以及包含其的有机发光元件

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3478208A (en) * 1967-01-04 1969-11-11 Atomic Energy Commission 2-aryl indoles and methods for their use
US3714148A (en) * 1968-10-15 1973-01-30 Sumitomo Chemical Co Process for preparing dibenzazocine derivatives and salts thereof
JPS6256471A (ja) * 1985-09-05 1987-03-12 Teikoku Hormone Mfg Co Ltd 含窒素四環式化合物

Also Published As

Publication number Publication date
NZ234174A (en) 1992-12-23
WO1990015800A1 (en) 1990-12-27
EP0404536A1 (en) 1990-12-27
PL285753A1 (en) 1991-03-25
AU5829990A (en) 1991-01-08
KR920702680A (ko) 1992-10-06
JO1629B1 (en) 1991-11-27
IS3589A7 (is) 1990-12-23
ZA904826B (en) 1991-04-24
MX21243A (es) 1994-01-31
IE902246A1 (en) 1991-01-16
DD298388A5 (de) 1992-02-20
CN1049156A (zh) 1991-02-13
IL94829A0 (en) 1991-04-15
US5185360A (en) 1993-02-09
JO1622B1 (en) 1991-11-27
LTIP911A (en) 1995-03-27
SE8902273D0 (sv) 1989-06-22
NO915050D0 (no) 1991-12-20
HU904780D0 (en) 1992-03-30
CA2062830A1 (en) 1990-12-23
PT94467A (pt) 1991-02-08
TW198025B (is) 1993-01-11
IE902246L (en) 1990-12-22
AU644082B2 (en) 1993-12-02
YU122290A (sh) 1992-09-07
HRP920897A2 (hr) 1994-04-30
HUT59096A (en) 1992-04-28
NO915050L (no) 1992-02-21
JPH04506515A (ja) 1992-11-12
FI915998A0 (fi) 1991-12-19
PL166155B1 (pl) 1995-04-28
FI915998A7 (fi) 1991-12-19

Similar Documents

Publication Publication Date Title
DE69836332T2 (de) Benzyliden-1,3-dihydro-indol-2-on-derivate als inhibitoren von rezeptor tyrosin kinasen, insbesondere von raf kinasen
HUE030848T2 (hu) Benzilidén-guanidin-származékok és terápiás alkalmazásuk fehérjék hibás feltekeredésével összefüggõ betegségek kezelésében
US12410142B2 (en) Substituted imidazole salt compounds, preparation method thereof, pharmaceutical composition thereof and application thereof
WO2016091042A1 (zh) 吡啶甲酰胺类衍生物、其制备方法及其在医药上的应用
BG60647B1 (bg) Инденоиндолови съединения
JP3064411B2 (ja) インデノインドール化合物▲ｉｉ▼
JPS63141955A (ja) トリベンジルアミン誘導体
AP339A (en) Indenoindoles compounds.
WO2023186137A1 (zh) 吲哚酮衍生物及其在医药上的应用
CN103044460A (zh) 3,5,7-三苯基-5H-噻唑并[3,2-a]嘧啶类衍生物及应用
JPS63264580A (ja) ３−（２−ハロアルキル）−１，４−オキサチインおよび２−（２−ハロアルキル）−１，４−ジチイン
EP0425282A2 (en) Triazolo derivatives and process for their preparation
KR102421065B1 (ko) 새로운 퀴논-인돌리진 하이브리드 유도체 제조방법 및 이를 포함하는 항암제 조성물
JP5371763B2 (ja) プロテインキナーゼｃｋ２の新規阻害物質としての置換インデノ［１，２−ｂ］インドール誘導体及び腫瘍治療剤、細胞増殖抑制剤及び診断剤としてのその使用
EP4737452A1 (en) Novel pyrimidine derivatives
BR112015016433B1 (pt) Uso de um composto de formula (i) para tratar um disturbio associado com a tensão do dobramento incorreto da proteína
KR20200023236A (ko) 벤조산 유도체 및 이를 유효성분으로 함유하는 자가면역질환 예방 또는 치료용 조성물
KR20040086352A (ko) 3-아릴-2,5-다이하이드록시-1,4-벤조퀴논 유도체, 이의제조 방법 및 이를 포함하는 약제 조성물
HK40039902A (en) Compounds for treatment of cardiac arrhythmias and heart failure