BG94402A - Метод за получаване на 2,2-диметил-5-(2,5-диметилфенокси)- пентанова киселина,междинни съединения за получаването й и метод за получаване на междинните съединения - Google Patents
Метод за получаване на 2,2-диметил-5-(2,5-диметилфенокси)- пентанова киселина,междинни съединения за получаването й и метод за получаване на междинните съединенияInfo
- Publication number
- BG94402A BG94402A BG094402A BG9440291A BG94402A BG 94402 A BG94402 A BG 94402A BG 094402 A BG094402 A BG 094402A BG 9440291 A BG9440291 A BG 9440291A BG 94402 A BG94402 A BG 94402A
- Authority
- BG
- Bulgaria
- Prior art keywords
- obtaining
- intermediate compounds
- dimethyl
- dimethylphenoxy
- general formula
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 4
- 150000001875 compounds Chemical class 0.000 title abstract 3
- HEMJJKBWTPKOJG-UHFFFAOYSA-N Gemfibrozil Chemical class CC1=CC=C(C)C(OCCCC(C)(C)C(O)=O)=C1 HEMJJKBWTPKOJG-UHFFFAOYSA-N 0.000 title 1
- 150000002148 esters Chemical class 0.000 abstract 3
- NKTOLZVEWDHZMU-UHFFFAOYSA-N 2,5-xylenol Chemical compound CC1=CC=C(C)C(O)=C1 NKTOLZVEWDHZMU-UHFFFAOYSA-N 0.000 abstract 2
- 125000002947 alkylene group Chemical group 0.000 abstract 2
- 125000005843 halogen group Chemical group 0.000 abstract 2
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical group [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 1
- KZBUYRJDOAKODT-UHFFFAOYSA-N Chlorine Chemical compound ClCl KZBUYRJDOAKODT-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000001447 alkali salts Chemical class 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- 125000005842 heteroatom Chemical group 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 125000001570 methylene group Chemical group [H]C([H])([*:1])[*:2] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/125—Saturated compounds having only one carboxyl group and containing ether groups, groups, groups, or groups
- C07C59/13—Saturated compounds having only one carboxyl group and containing ether groups, groups, groups, or groups containing rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/67—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids
- C07C69/708—Ethers
- C07C69/712—Ethers the hydroxy group of the ester being etherified with a hydroxy compound having the hydroxy group bound to a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/09—Preparation of carboxylic acids or their salts, halides or anhydrides from carboxylic acid esters or lactones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/62—Halogen-containing esters
- C07C69/63—Halogen-containing esters of saturated acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
Изобретението се отнася до метод за получаване на 2,2-диметил-5-/2,5-диметилфенокси/-пентанова киселина с формула който включва взаимодействие на естер с обща формула в която х е халогенен атом и z означава с1-8алкиленова група с права или разклонена верига, по желание заместена с една или две 2,2-диметил-5-халопентаноилоксигрупи, като хало означава хлорен или бромен атом, в алкиленовата група една или две метиленови групи са заместени с хетероатом/и/ или с двувалентна хетероциклена група, с алкална сол на 2,5-диметилфенол с формула или с негов естер, образуван с нисша алканова киселина, и хидролиза на получения арилоксисубституиран естер с обща формула изобретението се отнася и до междинните съединения с обща формула х, в която х и z имат посочените значения, както и до метод за получаването им. 10 претенции
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU902997A HU205891B (en) | 1990-05-11 | 1990-05-11 | Process for producing 2,2-dimethyl-5-/2,5-dimethyl-phenoxy/-pentanoic acid |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BG94402A true BG94402A (bg) | 1993-12-24 |
| BG60580B1 BG60580B1 (bg) | 1995-09-29 |
Family
ID=10962060
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG94402A BG60580B1 (bg) | 1990-05-11 | 1991-05-10 | Метод за получаване на 2,2-диметил-5-(2,5-диметилфенокси)- пентанова киселина,междинни съединения за получаването й и метод за получаване на междинните съединения |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US5155260A (bg) |
| JP (1) | JP2511335B2 (bg) |
| KR (1) | KR910019953A (bg) |
| CN (1) | CN1032134C (bg) |
| AT (1) | AT400716B (bg) |
| BG (1) | BG60580B1 (bg) |
| CA (1) | CA2042304A1 (bg) |
| CH (1) | CH683340A5 (bg) |
| CZ (1) | CZ282906B6 (bg) |
| DE (1) | DE4115540A1 (bg) |
| DK (1) | DK88091A (bg) |
| ES (1) | ES2036438B1 (bg) |
| FI (1) | FI912303A7 (bg) |
| FR (1) | FR2661908B1 (bg) |
| GB (1) | GB2244271B (bg) |
| GR (1) | GR1002053B (bg) |
| HU (2) | HU205891B (bg) |
| IT (1) | IT1253707B (bg) |
| NL (1) | NL9100811A (bg) |
| PL (1) | PL290204A1 (bg) |
| RU (1) | RU2056403C1 (bg) |
| YU (1) | YU48481B (bg) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002543194A (ja) * | 1999-04-28 | 2002-12-17 | ドクター・レディーズ・ラボラトリーズ・リミテッド | 置換二環系ヘテロ環化合物、その製造方法、並びに抗肥満症及び抗高コレステロール血症剤としてのこれらの使用 |
| JP5549230B2 (ja) | 2010-01-13 | 2014-07-16 | 株式会社リコー | 測距装置、測距用モジュール及びこれを用いた撮像装置 |
| JP5809390B2 (ja) | 2010-02-03 | 2015-11-10 | 株式会社リコー | 測距・測光装置及び撮像装置 |
| JP5523993B2 (ja) | 2010-08-31 | 2014-06-18 | 富士フイルム株式会社 | 酸ハロゲン化物の製造方法、及び酸ハロゲン化物 |
| ES3065854T3 (en) | 2011-12-07 | 2026-05-08 | Alnylam Pharmaceuticals Inc | Biodegradable lipids for the delivery of active agents |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3674836A (en) * | 1968-05-21 | 1972-07-04 | Parke Davis & Co | 2,2-dimethyl-{11 -aryloxy-alkanoic acids and salts and esters thereof |
| US3759986A (en) * | 1970-03-30 | 1973-09-18 | Parke Davis & Co | Esters of 2,2-dimethyl-5-(aryloxy)-1-pentanols |
| US3847994A (en) * | 1970-03-30 | 1974-11-12 | Parke Davis & Co | 2,2-dimethyl-5-(aryloxy)-valeraldehydes |
| GB2025942A (en) * | 1978-05-31 | 1980-01-30 | Sori Soc Rech Ind | Phenoxyalkylcarboxylic acids |
| DK305884A (da) * | 1983-06-24 | 1984-12-25 | Yamanouchi Pharma Co Ltd | Phenoxyderivat, fremgangsmaade til fremstilling deraf og farmaceutisk praeparat indeholdende et saadant derivat |
| ES534473A0 (es) * | 1984-07-20 | 1985-06-01 | Valles Rodoreda Enrique | Procedimiento para la obtencion del acido 2, 2-dimetil-5(2, 5-xililoxi) valerico |
| ES8605217A1 (es) * | 1985-12-02 | 1986-03-16 | Servicios Y Suministros Farmac | Procedimiento de obtencion del acido 2,2-dimetil-5-(2,5-di- metil-fenoxi)valerico |
| ES8605216A1 (es) * | 1985-12-02 | 1986-03-16 | Servicios Y Suministros Farmac | Procedimiento para la obtencion del acido 2,2-dimetil-5-(2, 5-dimetil-fenoxi)valerico y sus sales farmaceuticamente aceptables |
| US4665226A (en) * | 1985-12-09 | 1987-05-12 | Warner-Lambert Company | Process for preparing 5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoic acid |
-
1990
- 1990-05-11 HU HU902997A patent/HU205891B/hu not_active IP Right Cessation
- 1990-05-11 HU HU9200347A patent/HU210180B/hu unknown
-
1991
- 1991-05-08 CZ CS911359A patent/CZ282906B6/cs not_active IP Right Cessation
- 1991-05-08 CH CH1387/91A patent/CH683340A5/de not_active IP Right Cessation
- 1991-05-10 KR KR1019910007588A patent/KR910019953A/ko not_active Withdrawn
- 1991-05-10 IT ITMI911290A patent/IT1253707B/it active IP Right Grant
- 1991-05-10 FR FR9105682A patent/FR2661908B1/fr not_active Expired - Fee Related
- 1991-05-10 FI FI912303A patent/FI912303A7/fi not_active Application Discontinuation
- 1991-05-10 RU SU914895518A patent/RU2056403C1/ru active
- 1991-05-10 CN CN91102985A patent/CN1032134C/zh not_active Expired - Fee Related
- 1991-05-10 NL NL9100811A patent/NL9100811A/nl not_active Application Discontinuation
- 1991-05-10 PL PL29020491A patent/PL290204A1/xx unknown
- 1991-05-10 AT AT0096791A patent/AT400716B/de not_active IP Right Cessation
- 1991-05-10 GR GR910100202A patent/GR1002053B/el unknown
- 1991-05-10 JP JP3135444A patent/JP2511335B2/ja not_active Expired - Lifetime
- 1991-05-10 GB GB9110157A patent/GB2244271B/en not_active Expired - Fee Related
- 1991-05-10 DK DK088091A patent/DK88091A/da not_active Application Discontinuation
- 1991-05-10 ES ES09101150A patent/ES2036438B1/es not_active Expired - Fee Related
- 1991-05-10 YU YU81391A patent/YU48481B/sh unknown
- 1991-05-10 BG BG94402A patent/BG60580B1/bg unknown
- 1991-05-10 US US07/698,081 patent/US5155260A/en not_active Expired - Fee Related
- 1991-05-10 CA CA002042304A patent/CA2042304A1/en not_active Abandoned
- 1991-05-13 DE DE4115540A patent/DE4115540A1/de not_active Withdrawn
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