BR0000073A - Produção de ácido l- ascórbico e ácido d-eritórbico - Google Patents
Produção de ácido l- ascórbico e ácido d-eritórbicoInfo
- Publication number
- BR0000073A BR0000073A BR0000073-6A BR0000073A BR0000073A BR 0000073 A BR0000073 A BR 0000073A BR 0000073 A BR0000073 A BR 0000073A BR 0000073 A BR0000073 A BR 0000073A
- Authority
- BR
- Brazil
- Prior art keywords
- acid
- keto
- erythorbic
- contacting
- production
- Prior art date
Links
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 title abstract 8
- CIWBSHSKHKDKBQ-DUZGATOHSA-N D-isoascorbic acid Chemical compound OC[C@@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-DUZGATOHSA-N 0.000 title abstract 3
- 239000002211 L-ascorbic acid Substances 0.000 title abstract 2
- 235000000069 L-ascorbic acid Nutrition 0.000 title abstract 2
- 229960005070 ascorbic acid Drugs 0.000 title abstract 2
- VBUYCZFBVCCYFD-JJYYJPOSSA-N 2-dehydro-D-gluconic acid Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)C(=O)C(O)=O VBUYCZFBVCCYFD-JJYYJPOSSA-N 0.000 abstract 2
- VBUYCZFBVCCYFD-NUNKFHFFSA-N 2-dehydro-L-idonic acid Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)C(=O)C(O)=O VBUYCZFBVCCYFD-NUNKFHFFSA-N 0.000 abstract 2
- VBUYCZFBVCCYFD-UHFFFAOYSA-N D-arabino-2-Hexulosonic acid Natural products OCC(O)C(O)C(O)C(=O)C(O)=O VBUYCZFBVCCYFD-UHFFFAOYSA-N 0.000 abstract 2
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 abstract 2
- 108090000790 Enzymes Proteins 0.000 abstract 2
- 102000004190 Enzymes Human genes 0.000 abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- 229930003268 Vitamin C Natural products 0.000 abstract 2
- 230000001476 alcoholic effect Effects 0.000 abstract 2
- 239000003960 organic solvent Substances 0.000 abstract 2
- 235000019154 vitamin C Nutrition 0.000 abstract 2
- 239000011718 vitamin C Substances 0.000 abstract 2
- 101000693619 Starmerella bombicola Lactone esterase Proteins 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 239000003963 antioxidant agent Substances 0.000 abstract 1
- 230000003078 antioxidant effect Effects 0.000 abstract 1
- 235000006708 antioxidants Nutrition 0.000 abstract 1
- 159000000007 calcium salts Chemical class 0.000 abstract 1
- 239000002778 food additive Substances 0.000 abstract 1
- 235000013373 food additive Nutrition 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 159000000000 sodium salts Chemical class 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/02—Oxygen as only ring hetero atoms
- C12P17/04—Oxygen as only ring hetero atoms containing a five-membered hetero ring, e.g. griseofulvin, vitamin C
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Patente de Invenção: <B>''PRODUçãO DE áCIDO L-ASCóRBICO E áCIDO D-ERITóRBICO''<D>. Um processo para produzir ácido L-ascórbico (vitamina C) a partir de ácido 2 - ceto - L - gulónico ou de ácido D-eritórbico de ácido 2 - ceto - D - glucónico compreende contactar ácido 2 - ceto - L - gulónico ou ácido 2 - ceto - D - glucónico, respectivamente, em solução com uma lactonase, particularmente uma pertencente à classe de enzima EC 3.1.1.x de acordo com a classificação da Nomenclatura de Enzimas. O solvente para esta reação pode ser água, um álcool aquoso, um solvente orgânico não alcoólico ou uma mistura de um álcool aquoso e um solvente orgânico não alcoólico. O contato é, geralmente realizado em uma faixa de temperatura de 0°C a 120°C e uma faixa de pH de 1,5 a 12. Em cada caso o material inicial pode estar na forma do ácido livre, do sal de sódio ou do sal de cálcio. A vitamina C, assim produzida, possui usos bem conhecidos, e o ácido D-eritórbico alternativamente produzido é útil como antioxidante para aditivos de alimentos.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP99100785 | 1999-01-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0000073A true BR0000073A (pt) | 2000-09-26 |
Family
ID=8237360
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0000073-6A BR0000073A (pt) | 1999-01-18 | 2000-01-17 | Produção de ácido l- ascórbico e ácido d-eritórbico |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6146860A (pt) |
| JP (1) | JP2000210094A (pt) |
| KR (1) | KR20000053496A (pt) |
| CN (1) | CN1219070C (pt) |
| AT (1) | ATE323172T1 (pt) |
| BR (1) | BR0000073A (pt) |
| CA (1) | CA2296020A1 (pt) |
| DE (1) | DE60027218D1 (pt) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU781277B2 (en) * | 2000-08-23 | 2005-05-12 | Dsm Ip Assets B.V. | Microbial production of L-ascorbic acid and D-erythorbic acid |
| CN1318600C (zh) * | 2001-11-09 | 2007-05-30 | Dsmip资产有限公司 | 生产l－抗坏血酸和d－异抗坏血酸的酶方法 |
| WO2004029268A1 (en) * | 2002-09-27 | 2004-04-08 | Dsm Ip Assets B.V. | Microbial production of vitamin c |
| US20040197299A1 (en) * | 2003-01-16 | 2004-10-07 | Societe L'oreal, S.A. | Topically applicable cosmetic/dermatological compositions comprising hydrolase polypeptides having amidase activity and/or products modulating the activity thereof |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4259443A (en) * | 1979-02-05 | 1981-03-31 | Bernard Wolnak And Associates, Inc. | Synthesis of ascorbic acid from lactose |
| DE19604798A1 (de) * | 1996-02-09 | 1997-08-14 | Herbstreith & Fox Kg Pektin Fa | Herstellung von L-Ascorbinsäure |
| US5817490A (en) * | 1996-05-17 | 1998-10-06 | Eastman Chemical Company | Enzymatic process for the manufacture of ascorbic acid 2-keto-L-gulonic acid and esters of 2-keto-L-gulonic acid |
| IL119731A0 (en) * | 1996-12-01 | 1997-03-18 | Yissum Res Dev Co | A process for the production of erythorbic acid |
-
2000
- 2000-01-13 CA CA002296020A patent/CA2296020A1/en not_active Abandoned
- 2000-01-13 AT AT00100617T patent/ATE323172T1/de not_active IP Right Cessation
- 2000-01-13 DE DE60027218T patent/DE60027218D1/de not_active Expired - Lifetime
- 2000-01-14 KR KR1020000001735A patent/KR20000053496A/ko not_active Abandoned
- 2000-01-14 JP JP2000005393A patent/JP2000210094A/ja not_active Withdrawn
- 2000-01-17 CN CNB001009907A patent/CN1219070C/zh not_active Expired - Fee Related
- 2000-01-17 BR BR0000073-6A patent/BR0000073A/pt not_active Application Discontinuation
- 2000-01-18 US US09/484,966 patent/US6146860A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CA2296020A1 (en) | 2000-07-18 |
| JP2000210094A (ja) | 2000-08-02 |
| US6146860A (en) | 2000-11-14 |
| ATE323172T1 (de) | 2006-04-15 |
| CN1263950A (zh) | 2000-08-23 |
| CN1219070C (zh) | 2005-09-14 |
| DE60027218D1 (de) | 2006-05-24 |
| KR20000053496A (ko) | 2000-08-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA10 | Dismissal: dismissal - article 33 of industrial property law | ||
| B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] |