BR0008657A - Comprimidos deglutìveis com teor elevado den-acetilcisteì na e processo para a preparação dosmesmos - Google Patents

Comprimidos deglutìveis com teor elevado den-acetilcisteì na e processo para a preparação dosmesmos

Info

Publication number
BR0008657A
BR0008657A BR0008657-6A BR0008657A BR0008657A BR 0008657 A BR0008657 A BR 0008657A BR 0008657 A BR0008657 A BR 0008657A BR 0008657 A BR0008657 A BR 0008657A
Authority
BR
Brazil
Prior art keywords
acetylcysteine
preparing
same
high den
swallow tablets
Prior art date
Application number
BR0008657-6A
Other languages
English (en)
Inventor
Franco Castegini
Alessandro Grassano
Riccardo Barina
Italo Zuliani
Giovanni Gurrieri
Original Assignee
Zambon Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zambon Spa filed Critical Zambon Spa
Publication of BR0008657A publication Critical patent/BR0008657A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/10—Expectorants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/12—Mucolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

"COMPRIMIDOS DEGLUTìVEIS COM TEOR ELEVADO DEN-ACETILCISTEìNA E PROCESSO PARA A PREPARAçãO DOSMESMOS". é descrito um comprimido deglutível que contém80-95% de N-acetilcisteína em peso, 0,5-4% em peso em relação àNacetilcisteína de um aglutinante e ainda excipientesfarmaceuticamente aceitáveis, tais como diluentes,desagregadores, lubrificantes, opcionalmente na presença de umagente circulante e de uma camada de revestimento de película.
BR0008657-6A 1999-04-06 2000-03-21 Comprimidos deglutìveis com teor elevado den-acetilcisteì na e processo para a preparação dosmesmos BR0008657A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT1999MI000704A IT1311907B1 (it) 1999-04-06 1999-04-06 Compresse deglutibili ad alto contenuto di n-acetilcisteina.
PCT/EP2000/002464 WO2000059500A1 (en) 1999-04-06 2000-03-21 Swallowable tablets with high content of n-acetylcysteine

Publications (1)

Publication Number Publication Date
BR0008657A true BR0008657A (pt) 2001-12-18

Family

ID=11382595

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0008657-6A BR0008657A (pt) 1999-04-06 2000-03-21 Comprimidos deglutìveis com teor elevado den-acetilcisteì na e processo para a preparação dosmesmos

Country Status (15)

Country Link
EP (1) EP1165065B1 (pt)
CN (1) CN1159004C (pt)
AT (1) ATE239463T1 (pt)
AU (1) AU4106800A (pt)
BR (1) BR0008657A (pt)
CA (1) CA2361843C (pt)
CO (1) CO4970828A1 (pt)
DE (1) DE60002570T2 (pt)
DK (1) DK1165065T3 (pt)
EA (1) EA003878B1 (pt)
ES (1) ES2197087T3 (pt)
HU (1) HU228823B1 (pt)
IT (1) IT1311907B1 (pt)
PT (1) PT1165065E (pt)
WO (1) WO2000059500A1 (pt)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0209265D0 (en) 2002-04-23 2002-06-05 Novartis Ag Organic compounds
US20060099253A1 (en) * 2004-10-20 2006-05-11 Wyeth Antibiotic product formulation
US7993578B2 (en) 2004-10-29 2011-08-09 Depuy Spine, Inc. Methods and kits for aseptic filling of products
US8513261B2 (en) * 2009-03-13 2013-08-20 Toyama Chemical Co., Ltd. Tablet and granulated powder containing 6-fluoro-3-hydroxy-2-pyrazinecarboxamide
EP2453743B1 (en) * 2009-07-15 2017-04-12 The Board of Trustees of The Leland Stanford Junior University N-acetyl cysteine compositions and their use in improving the therapeutic efficacy of acetaminophen
IT1399492B1 (it) * 2010-04-13 2013-04-19 Alpex Pharma Sa Composizioni farmaceutiche effervescenti contenenti n-acetilcisteina.
CN102028657B (zh) * 2010-12-02 2012-05-23 海南美兰史克制药有限公司 乙酰半胱氨酸脂质体固体制剂
CN102144978B (zh) * 2011-04-11 2013-03-13 南京正科制药有限公司 一种乙酰半胱氨酸颗粒及其制备工艺
CN102743369A (zh) * 2012-06-19 2012-10-24 苏州朗易生物医药研究有限公司 一种乙酰半胱氨酸的药物组合物及其制备方法
ITMI20130874A1 (it) * 2013-05-29 2014-11-30 Zambon Spa Compresse deglutibili di n-acetilcisteina
CN104784116B (zh) * 2015-04-15 2017-05-24 武汉诺贝药业有限公司 一种n‑乙酰半胱氨酸口服制剂
CA2937365C (en) 2016-03-29 2018-09-18 F. Hoffmann-La Roche Ag Granulate formulation of 5-methyl-1-phenyl-2-(1h)-pyridone and method of making the same
US20250235416A1 (en) * 2017-09-20 2025-07-24 Nacuity Pharmaceuticals, Inc. Method for preparation of n-acetyl cysteine amide, derivatives and tablets thereof
CN110292569B (zh) * 2019-07-15 2021-11-02 广东人人康药业有限公司 一种乙酰半胱氨酸胶囊及其制备方法
CN112843008A (zh) * 2021-02-07 2021-05-28 广东赛康制药厂有限公司 一种乙酰半胱氨酸片及其制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL88150A0 (en) * 1987-11-02 1989-06-30 Merck & Co Inc Pharmaceutical tablet compositions containing phthalizine acetic acid compounds
DK0481294T4 (da) * 1990-10-19 2001-06-18 Spirig Ag Fast, hurtigt-opløseligt lægemiddelpræparat indeholdende N-acetylcystein
ZA963590B (en) * 1995-05-10 1996-11-19 Adcock Ingram Ltd Pharmaceutical composition

Also Published As

Publication number Publication date
CA2361843C (en) 2008-10-14
HU228823B1 (en) 2013-05-28
EA200100947A1 (ru) 2002-04-25
ES2197087T3 (es) 2004-01-01
WO2000059500A1 (en) 2000-10-12
EA003878B1 (ru) 2003-10-30
DE60002570D1 (de) 2003-06-12
CA2361843A1 (en) 2000-10-12
DK1165065T3 (da) 2003-09-01
PT1165065E (pt) 2003-08-29
ITMI990704A1 (it) 2000-10-06
ATE239463T1 (de) 2003-05-15
EP1165065A1 (en) 2002-01-02
HUP0200646A2 (hu) 2002-07-29
CN1159004C (zh) 2004-07-28
CO4970828A1 (es) 2000-11-07
DE60002570T2 (de) 2004-02-26
AU4106800A (en) 2000-10-23
EP1165065B1 (en) 2003-05-07
IT1311907B1 (it) 2002-03-20
CN1345236A (zh) 2002-04-17

Similar Documents

Publication Publication Date Title
BR0008657A (pt) Comprimidos deglutìveis com teor elevado den-acetilcisteì na e processo para a preparação dosmesmos
ATE189400T1 (de) Knochenwachstumsfördernde zusammensetzung
AR033796A1 (es) Composicion farmaceutica
ES2097826T3 (es) Matriz de liberacion controlada para composiciones farmaceuticas.
ES2127850T3 (es) Sulfonilaminopirimidinas, su obtencion y utilizacion como medicamentos.
BR0211801A (pt) Derivados de 7h-pirrolo[2,3-d]pirimidina
AR085778A2 (es) Forma de dosis solida enterica revestida, que comprende acido micofenolico o sal micofenolato
BR0308212A (pt) Composto, composição farmacêutica, e, uso de um composto
ES2190692A1 (es) Formulacion farmaceutica de amoxicilina y clavulanato de potasio.
PT90478A (pt) Processo para a preparacao de derivados da purina e de composicoes farmaceuticas que os contem
EA200001201A2 (ru) Таблетка с основой, позволяющая осуществлять пролонгированное высвобождение триметазидина после введения оральным путем
BR0311460A (pt) Composição farmacêutica de liberação modificada, uso de uma formulação, e, método para tratar um distúrbio cardiovascular em um paciente
DK616186A (da) Farmaceutisk praeparat med retarderet frigivelse af ibuprofen
BRPI0513673B8 (pt) método para produzir um medicamento para aumentar a eficácia e o transporte dos compostos biologicamente ativos enteralmente administrados, e composição farmacêutica
GEP20043162B (en) Derivatives of Isosorbid Mononitrate, Utilization as Vasodilator Agents with Reduced Tolerance
BRPI0412391A (pt) formulação farmacêutica compreendendo levotiroxina sódica
EA200100540A1 (ru) Фармацевтическая композиция с модифицированным высвобождением сенсибилизатора к инсулину
RU98106625A (ru) Производные колхицина и тиоколхицина, обладающие противовоспалительной и миорелаксирующей активностями
ES2078838A1 (es) Procedimiento para preparar una composicion a base de clozapina.
AR039162A1 (es) Formulaciones de venlafaxina de liberacion extendida
MX9305887A (es) Uso de acido hialuronico y formas para evitar restenosis arterial.
AR008619A1 (es) Utilizacion de la flupirtina para la profilaxis y la terapia de enfermedades que se acompanan de una tasa de mortalidad celular mas alta que lafisiologia y medicamentos que comprenden flupirtina para dicha profilaxis y dicha terapia.
BR9917601A (pt) Composição farmacêutica para inibir a toxidade reprodutora de um macho
BRPI0411749A (pt) método para a inibição do crescimento de bactérias resistentes a antibióticos pelo uso de pentano-1,5-diol
ATE267585T1 (de) Micronisierte pharmazeutische zusammensetzungen

Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B15K Others concerning applications: alteration of classification

Free format text: ALTERADA DA INT.CL: A61K 9/20, A61K 9/36, A61K 31/198, A61K 9/30, A61K 31/185

Ipc: A61K 9/20 (2009.01), A61K 9/36 (2009.01), A61K 31/

B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFERIDO O PEDIDO COM BASE NOS ARTIGOS 8O E 13 DA LPI.

B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL.