BR0010677B1 - processo de purificaÇço de gonadotropinas urinÁrias humanas a partir de gonadotropinas brutas. - Google Patents

processo de purificaÇço de gonadotropinas urinÁrias humanas a partir de gonadotropinas brutas.

Info

Publication number
BR0010677B1
BR0010677B1 BRPI0010677-1A BR0010677A BR0010677B1 BR 0010677 B1 BR0010677 B1 BR 0010677B1 BR 0010677 A BR0010677 A BR 0010677A BR 0010677 B1 BR0010677 B1 BR 0010677B1
Authority
BR
Brazil
Prior art keywords
gonadotropins
crude
purification process
human urinary
menotropins
Prior art date
Application number
BRPI0010677-1A
Other languages
English (en)
Other versions
BR0010677A (pt
BRPI0010677B8 (pt
Inventor
Claudio Fernando Wolfenson Band
Liliana Ester Balanian
Jose Felipe Groisman
Erundina Marta Fasanella
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of BR0010677A publication Critical patent/BR0010677A/pt
Publication of BR0010677B1 publication Critical patent/BR0010677B1/pt
Publication of BRPI0010677B8 publication Critical patent/BRPI0010677B8/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g.hCG [human chorionic gonadotropin]; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Endocrinology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Reproductive Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BRPI0010677A 1999-04-16 2000-04-14 processo de purificação de gonadotropinas urinárias humanas a partir de gonadotropinas brutas. BRPI0010677B8 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12954099P 1999-04-16 1999-04-16
PCT/EP2000/003357 WO2000063248A2 (en) 1999-04-16 2000-04-14 Highly purified gonadotropin compositions and process for preparing them

Publications (3)

Publication Number Publication Date
BR0010677A BR0010677A (pt) 2002-02-05
BR0010677B1 true BR0010677B1 (pt) 2013-04-30
BRPI0010677B8 BRPI0010677B8 (pt) 2021-05-25

Family

ID=22440494

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0010677A BRPI0010677B8 (pt) 1999-04-16 2000-04-14 processo de purificação de gonadotropinas urinárias humanas a partir de gonadotropinas brutas.

Country Status (13)

Country Link
EP (1) EP1169349B1 (pt)
JP (1) JP4574865B2 (pt)
AT (1) ATE358139T1 (pt)
AU (1) AU779005B2 (pt)
BR (1) BRPI0010677B8 (pt)
CA (1) CA2370225C (pt)
CY (1) CY1107666T1 (pt)
DE (1) DE60034117T2 (pt)
DK (1) DK1169349T3 (pt)
ES (1) ES2284494T3 (pt)
MX (1) MXPA01010522A (pt)
PT (1) PT1169349E (pt)
WO (1) WO2000063248A2 (pt)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2544333A1 (en) 2003-12-22 2005-07-14 Ares Trading S.A. Method for purifying fsh
AU2005303818B2 (en) * 2004-11-09 2011-06-23 Ares Trading S.A. Method for purifying FSH
UA87709C2 (ru) * 2004-11-09 2009-08-10 Эйрэс Трейдинг С.А. Способ очищения фолликулостимулирующего гормона
SG155183A1 (en) 2005-08-26 2009-09-30 Ares Trading Sa Process for the preparation of glycosylated interferon beta
EP1960419B1 (en) * 2005-12-09 2016-03-16 Ares Trading S.A. Method for purifying fsh or a fsh mutant
RS52976B (sr) 2007-06-28 2014-02-28 Biogenerix Ag Ćelijski klon koji proizvodi fsh
EP2249869B1 (en) 2008-02-08 2011-09-07 BioGeneriX AG Liquid formulation of fsh
CN101269215B (zh) * 2008-05-15 2011-03-23 上海天伟生物制药有限公司 一种糖蛋白激素组合物
MX2011010480A (es) 2009-04-01 2012-09-07 Biogenerix Ag Metodo para purificar una fsh recombinante.
EP2325194A1 (en) 2009-11-24 2011-05-25 Glycotope GmbH Process for the purification of glycoproteins
CN103159846B (zh) * 2013-04-09 2015-04-22 邹平县滨渤生物科技有限公司 Hmg粗品的制备方法
ES2719748T3 (es) 2014-05-23 2019-07-12 Inst Massone S A Proceso para obtener HMG-UP (gonadotropina menopáusica humana con grado de ultrapureza) y una composición libre de contaminantes
MD3261661T2 (ro) 2015-02-26 2024-04-30 Ferring Bv Menotropină pentru tratarea infertilității
CN108070640B (zh) * 2018-01-12 2021-09-21 浙江省农业科学院 一种与卵泡刺激素剂量呈线性相关的基因的筛选方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1065127A (en) * 1963-03-11 1967-04-12 Serono Ist Farm Pituitary gonadotropic hormone preparation and method for its production
IT1287138B1 (it) * 1996-11-07 1998-08-04 Ibsa Inst Biochimique Sa Procedimento per la separazione e purificazione di fsh e lh

Also Published As

Publication number Publication date
CY1107666T1 (el) 2013-04-18
JP2002542260A (ja) 2002-12-10
BR0010677A (pt) 2002-02-05
DK1169349T3 (da) 2007-07-30
JP4574865B2 (ja) 2010-11-04
AU4549100A (en) 2000-11-02
WO2000063248A2 (en) 2000-10-26
ATE358139T1 (de) 2007-04-15
CA2370225C (en) 2010-06-29
DE60034117D1 (de) 2007-05-10
DE60034117T2 (de) 2007-12-13
AU779005B2 (en) 2004-12-23
PT1169349E (pt) 2007-06-18
ES2284494T3 (es) 2007-11-16
WO2000063248A3 (en) 2001-02-01
EP1169349B1 (en) 2007-03-28
CA2370225A1 (en) 2000-10-26
BRPI0010677B8 (pt) 2021-05-25
EP1169349A2 (en) 2002-01-09
MXPA01010522A (es) 2003-08-19

Similar Documents

Publication Publication Date Title
CY1107666T1 (el) Διαδικασια για την παρασκευη συνθεσεων γοναδοτροπινης
US5362852A (en) Modified peptide derivatives conjugated at 2-hydroxyethylamine moieties
Violette et al. Large-scale discovery of conopeptides and conoproteins in the injectable venom of a fish-hunting cone snail using a combined proteomic and transcriptomic approach
Rattenholl et al. Pro-sequence assisted folding and disulfide bond formation of human nerve growth factor
PL366364A1 (en) Process for producing peptides by using in vitrotranscription/translation system
IL129299A0 (en) Monoclonal antibodies antigens and diagnosis of malignant diseases
MXPA03007619A (es) Nuevas moleculas similares a interferon beta.
EP0695171A1 (en) GONADOTROPINE CONTAINING FREEZER DRIED DROPS
AR038568A1 (es) Anticuerpos anti-a beta y su uso
Wang et al. Revisiting oxytocin through the medium of isonitriles
CY1108460T1 (el) Μεθοδος για τον καθαρισμο ανασυνδυασμενης hcg (ανθρωπινης χοριονικης γοναδοτροπινης) που εχει ειδικη βιοδραστικοτητα
WO2002085311A3 (en) Hcg formulation
Strydom et al. Sensitive analysis of cystine/cysteine using 6-aminoquinolyl-N-hydroxysuccinimidyl carbamate (AQC) derivatives
SK10395A3 (en) Polypeptide and its using
Browning et al. Disulfide scrambling of interleukin-2: HPLC resolution of the three possible isomers
EP1258494A1 (en) Multiprotein complexes from eukaryotes
BR0108553A (pt) HormÈnio luteinizante (lh) purificado
AU2003267551A1 (en) Thieno-pyrrole compounds as antagonists of gonadotropin releasing hormone
ATE472337T1 (de) Pharmazeutische zusammensetzung aus f(ab) 2- fragmenten von antikörpern und verfahren zu ihrer herstellung
Spetzler et al. A novel strategy for the synthesis of the cysteine‐rich protective antigen of the malaria merozoite surface protein (MSP‐1) Knowledge‐based strategy for disulfide formation
BR0211991A (pt) HormÈnio do crescimento humano modificado
Lundquist et al. Synthesis and Human Neurotensin Receptor Binding Activities of Neurotensin (8− 13) Analogues Containing Position 8 α-Azido-N-alkylated Derivatives of Ornithine, Lysine, and Homolysine
Langer et al. A bicyclic cispentacin derivative as a novel reverse turn inducer in a GnRH mimetic
Bishop et al. Dimethyl (methylthio) sulfonium tetrafluoroborate: a reagent for disulfide bond formation in peptides
Guan et al. N-terminus determination: FAD and NADP binding domain mapping of hog liver flavin-containing monooxygenase by tandem mass spectrometry

Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B09X Republication of the decision to grant [chapter 9.1.3 patent gazette]

Free format text: REPUBLICACAO DA PUBLICACAO DE DEFERIMENTO POR TER SIDO EFETUADA COM INCORRECAO.

B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 30/04/2013, OBSERVADAS AS CONDICOES LEGAIS.

B16C Correction of notification of the grant [chapter 16.3 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 14/04/2000 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF

B21A Patent or certificate of addition expired [chapter 21.1 patent gazette]

Free format text: PATENTE EXTINTA EM 14/04/2020