BR0011449A - Método para detectar sìfilis usando antìgenos sintéticos - Google Patents

Método para detectar sìfilis usando antìgenos sintéticos

Info

Publication number
BR0011449A
BR0011449A BR0011449-9A BR0011449A BR0011449A BR 0011449 A BR0011449 A BR 0011449A BR 0011449 A BR0011449 A BR 0011449A BR 0011449 A BR0011449 A BR 0011449A
Authority
BR
Brazil
Prior art keywords
antigen composition
pallidum
synthetic antigens
syphilis
infection
Prior art date
Application number
BR0011449-9A
Other languages
English (en)
Other versions
BR0011449B1 (pt
BRPI0011449B8 (pt
Inventor
Victoria Pope
Arnold R Castro
William E Morrill
Original Assignee
Us Health
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Us Health filed Critical Us Health
Publication of BR0011449A publication Critical patent/BR0011449A/pt
Publication of BR0011449B1 publication Critical patent/BR0011449B1/pt
Publication of BRPI0011449B8 publication Critical patent/BRPI0011449B8/pt

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/571—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses for venereal disease, e.g. syphilis, gonorrhoea
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • G01N2333/20—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Spirochaetales (O), e.g. Treponema, Leptospira
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2405/00—Assays, e.g. immunoassays or enzyme assays, involving lipids
    • G01N2405/04—Phospholipids, i.e. phosphoglycerides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Patente de Invenção: "MéTODO PARA DETECTAR SìFILIS USANDO ANTìGENOS SINTéTICOS". A presente invenção se refere a uma composição de antígeno e a um método para detecção de anticorpos ao Treponema pallidum e também à diagnose de sífilis. A composição de antígeno contém cardiolipina sintética e lecitina sintética. A composição de antígeno pode adicionalmente conter colesterol e um álcool. A composição de antígeno é de utilidade como um imunoreagente em imunoensaios para a detecção de anticorpos associados à infecção causada por T. pallidum. Os métodos são sensíveis e específicos para infecção causada pela T. pallidum.
BRPI0011449A 1999-06-09 2000-06-08 composição de antígeno compreendendo tetramiristoil cardiolipina e 1-palmitoil-2-oleil-sn-glicero-3-fosfocolina e método para detectar anticorpos anti-lipoidais em uma amostra humana biológica in vitro BRPI0011449B8 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13819299P 1999-06-09 1999-06-09
PCT/US2000/015828 WO2000075666A1 (en) 1999-06-09 2000-06-08 Method for detecting syphilis using synthetic antigens

Publications (3)

Publication Number Publication Date
BR0011449A true BR0011449A (pt) 2002-03-19
BR0011449B1 BR0011449B1 (pt) 2013-12-03
BRPI0011449B8 BRPI0011449B8 (pt) 2021-05-25

Family

ID=22480887

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0011449A BRPI0011449B8 (pt) 1999-06-09 2000-06-08 composição de antígeno compreendendo tetramiristoil cardiolipina e 1-palmitoil-2-oleil-sn-glicero-3-fosfocolina e método para detectar anticorpos anti-lipoidais em uma amostra humana biológica in vitro

Country Status (10)

Country Link
EP (1) EP1185872B1 (pt)
JP (1) JP4531314B2 (pt)
CN (1) CN1195986C (pt)
AT (1) ATE316245T1 (pt)
AU (1) AU771548B2 (pt)
BR (1) BRPI0011449B8 (pt)
CA (1) CA2375448C (pt)
DE (1) DE60025605T2 (pt)
RU (1) RU2244933C2 (pt)
WO (1) WO2000075666A1 (pt)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10250368A1 (de) * 2002-10-29 2004-05-19 Viramed Biotech Ag Mittel und Verfahren zur Diagnose einer Treponemainfektion
RU2270450C1 (ru) * 2004-08-20 2006-02-20 Государственное образовательное учреждение высшего профессионального образования "Пермская государственная медицинская академия Министерства Здравоохранения Российской Федерации" Способ диагностики сифилиса
BRPI0611866B8 (pt) 2005-06-21 2021-07-27 The Government Of The Us Secretary Of The Department Of Health And Human Services Centers For Diseas dispositivo de fluxo lateral de imunoensaio, dispositivo de fluxo direto de imunoensaio, método para detectar anticorpos antilipoidais em um sujeito, método para para diagnosticar sífilis em um sujeito e métodos para imobilizar cardiolipina imunorreativa sobre um substrato microporoso
US8148057B2 (en) 2005-06-21 2012-04-03 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services, Centers For Disease Control And Prevention Methods, immunoassays and devices for detection of anti-lipoidal antibodies
JP4837743B2 (ja) 2005-11-18 2011-12-14 アメリカ合衆国 修飾カルジオリピンおよびその使用法
US8778619B2 (en) 2005-11-18 2014-07-15 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Oxidized cardiolipin and uses to detect cardiolipin antibodies
JP4629563B2 (ja) * 2005-12-07 2011-02-09 積水メディカル株式会社 抗リン脂質抗体測定試薬
CA2631636C (en) * 2005-12-07 2014-06-03 Sekisui Medical Co., Ltd. Reagent for assaying antiphospholipid antibody and reagent for assaying anti-treponema pallidum antibody
RU2327170C2 (ru) * 2006-02-27 2008-06-20 Закрытое акционерное общество "ДиТест" Способ комплексной диагностики вирусного гепатита в, вирусного гепатита с, вич-инфекции и сифилиса
RU2394496C1 (ru) * 2009-03-11 2010-07-20 Федеральное Государственное Учреждение "Государственный Научный Центр Дерматовенерологии Федерального Агентства По Высокотехнологичной Медицинской Помощи" Способ диагностики сифилиса путем одновременного определения реагиновых и трепонемоспецифических антител к t.pallidum на микроскопных альдегидных слайдах
RU2421730C1 (ru) * 2010-04-09 2011-06-20 Государственное образовательное учреждение высшего профессионального образования "Красноярский государственный медицинский университет имени профессора В.Ф. Войно-Ясенецкого Министерства здравоохранения и социального развития Российской Федерации" Способ диагностики раннего врожденного сифилиса скрытого
CN102095861A (zh) * 2011-01-25 2011-06-15 厦门大学附属中山医院 梅毒特异性总抗体和心磷脂抗体免疫印迹试剂盒及其制备
RU2474820C2 (ru) * 2011-04-11 2013-02-10 Виктория Олеговна Пожарская Способ контроля эффективности лечения сифилиса
US8945827B2 (en) 2013-03-13 2015-02-03 Awareness Technology, Inc. Serological methods and diagnostic tests for syphilis antibodies
CN104049081B (zh) * 2013-03-13 2016-03-09 意识科技股份有限公司 针对梅毒抗体的血清学方法和诊断测试
GB201400819D0 (en) 2014-01-17 2014-03-05 Sec Dep For Health The Mycobacterial antigen composition
CN107533060B (zh) 2015-03-10 2019-11-05 生物辐射实验室股份有限公司 组合密螺旋体和非密螺旋体梅毒测试
CN116449007B (zh) * 2022-12-28 2026-06-05 珠海丽珠试剂股份有限公司 梅毒螺旋体抗体检测试剂盒及其应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1053504A (pt) * 1964-03-17 1967-01-04
EP0009088A1 (de) * 1978-09-18 1980-04-02 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Reagenz zur Bestimmung von Wassermann-Antikörpern, Verfahren zu dessen Herstellung, Anwendung und Verwendung dieses Reagenzes zur Bestimmung von Wassermann-Antikörpern sowie entsprechende Reagenziengarnitur

Also Published As

Publication number Publication date
BR0011449B1 (pt) 2013-12-03
RU2244933C2 (ru) 2005-01-20
JP4531314B2 (ja) 2010-08-25
ATE316245T1 (de) 2006-02-15
CN1353815A (zh) 2002-06-12
AU5475600A (en) 2000-12-28
CN1195986C (zh) 2005-04-06
AU771548B2 (en) 2004-03-25
EP1185872B1 (en) 2006-01-18
WO2000075666A1 (en) 2000-12-14
CA2375448A1 (en) 2000-12-14
DE60025605D1 (de) 2006-04-06
DE60025605T2 (de) 2006-11-09
JP2003501662A (ja) 2003-01-14
CA2375448C (en) 2009-04-07
EP1185872A1 (en) 2002-03-13
BRPI0011449B8 (pt) 2021-05-25

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B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
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B09A Decision: intention to grant [chapter 9.1 patent gazette]
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