BR0012326A - Formulações lìquidas farmacêuticas de gosto mascarado - Google Patents

Formulações lìquidas farmacêuticas de gosto mascarado

Info

Publication number
BR0012326A
BR0012326A BR0012326-9A BR0012326A BR0012326A BR 0012326 A BR0012326 A BR 0012326A BR 0012326 A BR0012326 A BR 0012326A BR 0012326 A BR0012326 A BR 0012326A
Authority
BR
Brazil
Prior art keywords
pharmaceutical formulations
acidic
taste
liquid composition
cellulose ester
Prior art date
Application number
BR0012326-9A
Other languages
English (en)
Inventor
Danny Yu
Edward Roche
Original Assignee
Ortho Mcneil Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Mcneil Pharm Inc filed Critical Ortho Mcneil Pharm Inc
Publication of BR0012326A publication Critical patent/BR0012326A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5383—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Patente de Invenção: "FORMULAçõES LìQUIDAS FARMACêUTICAS DE GOSTO MASCARADO". Uma composição líquida para administração oral compreendendo um medicamento farmaceuticamente ativo revestido com uma quantidade eficaz mascaradora de gosto de uma mistura de um polímero de (a) metacrilato dedimetilaminoetila e éster de ácido metacrílico neutro (MM/MMAE) e (b) um éster de celulose, em um veículo aquoso, onde a razão em peso de polímero do éster de celulose para o MM/MAE é de cerca de 40:60 a cerca de 90:10, preferivelmente cerca de 60:40. A composição líquida utiliza um "revestimento entérico reverso" que é solúvel no pH ácido do estómago, geralmente cerca de 1,0 a 4,0, mas relativamente insolúvel no pH não-ácido da boca. Os revestimentos provêm liberação e absorção rápida da droga, o que é geralmente desejável no caso de formas de dosagens líquidas.
BR0012326-9A 1999-07-09 2000-06-21 Formulações lìquidas farmacêuticas de gosto mascarado BR0012326A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14301999P 1999-07-09 1999-07-09
PCT/US2000/016969 WO2001003698A1 (en) 1999-07-09 2000-06-21 Taste masked pharmaceutical liquid formulations

Publications (1)

Publication Number Publication Date
BR0012326A true BR0012326A (pt) 2002-03-12

Family

ID=22502238

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0012326-9A BR0012326A (pt) 1999-07-09 2000-06-21 Formulações lìquidas farmacêuticas de gosto mascarado

Country Status (25)

Country Link
US (2) US6482823B1 (pt)
EP (1) EP1194153B1 (pt)
JP (1) JP2003504335A (pt)
KR (2) KR100675809B1 (pt)
CN (1) CN1174740C (pt)
AR (1) AR027179A1 (pt)
AT (1) ATE265852T1 (pt)
AU (1) AU773555B2 (pt)
BR (1) BR0012326A (pt)
CA (1) CA2377916C (pt)
DE (1) DE60010464T2 (pt)
DK (1) DK1194153T3 (pt)
EE (1) EE05147B1 (pt)
ES (1) ES2219360T3 (pt)
HR (1) HRP20020119A2 (pt)
HU (1) HUP0201765A3 (pt)
IL (2) IL147510A0 (pt)
MX (1) MXPA02000331A (pt)
NO (1) NO20020086L (pt)
NZ (1) NZ516486A (pt)
PL (1) PL197812B1 (pt)
PT (1) PT1194153E (pt)
SK (1) SK322002A3 (pt)
TR (1) TR200200710T2 (pt)
WO (1) WO2001003698A1 (pt)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2284643T3 (es) * 2000-04-20 2007-11-16 Novartis Ag Composicion de revestimiento enmascarante del sabor.
MXPA03008056A (es) * 2001-03-05 2004-10-15 Johnson & Johnson Composiciones farmaceuticas liquidas con sabor oculto.
US20040013737A1 (en) * 2002-07-19 2004-01-22 Philippe Becourt Taste masked oral composition of telithromycin
WO2004013047A2 (en) * 2002-08-02 2004-02-12 Eggs In The Pipeline, Llc. System for adding consumable enhancing additives to drinking water
US20080020096A1 (en) * 2003-08-01 2008-01-24 Blum Bradley J System for Adding Consumable Enhancing Additives to Drinking Water
EP1669090B1 (en) * 2003-09-12 2016-03-30 Ryukakusan Co. Ltd. Bitterness-masking particulate jelly beverage
US7713482B2 (en) 2003-12-18 2010-05-11 The Clorox Company Control scheme for enhanced filtered water systems
US7378015B2 (en) * 2003-12-18 2008-05-27 The Clorox Company Filtered water enhancements
US8236349B2 (en) 2004-04-12 2012-08-07 Bend Research Inc. Taste-masked drugs in rupturing multiparticulates
JP2006232789A (ja) * 2005-02-28 2006-09-07 Sawai Pharmaceutical Co Ltd 経口製剤用組成物及びその製造方法
US20060216355A1 (en) * 2005-03-28 2006-09-28 Donald Spector Encapsulated pharmaceuticals in a medium having non-encapsulated flavoring agents
US8458475B2 (en) * 2005-06-20 2013-06-04 Authentiform Technologies, L.L.C. Systems and methods for product authentication
US8247018B2 (en) * 2005-06-20 2012-08-21 Authentiform Technologies, Llc Methods for quality control
US7874489B2 (en) * 2005-06-20 2011-01-25 Authentiform Technologies, Llc Product authentication
US20070197469A1 (en) * 2006-02-17 2007-08-23 Murthy Yerramilli V Fluoroquinolone carboxylic acid salt compositions
US7973022B2 (en) * 2006-02-17 2011-07-05 Idexx Laboratories, Inc. Fluoroquinolone carboxylic acid salt compositions
WO2008065504A1 (en) 2006-11-30 2008-06-05 Pfizer Products Inc. Multiparticulates of spray-coated drug and polymer on a meltable core
ES2552723T3 (es) * 2008-05-06 2015-12-01 Dexcel Pharma Technologies Ltd. Formulación de bencimidazol estable
CN101618217B (zh) * 2009-07-27 2011-12-28 洛阳君山制药有限公司 一种安胃片的包衣方法
KR101636958B1 (ko) * 2009-09-11 2016-07-06 주식회사 대웅제약 우루소데옥시콜린산-합성하이드로탈사이트-유드라짓 혼성체, 이를 함유하는 약학 조성물 및 그 제조방법
CA2783877A1 (en) * 2009-12-10 2011-06-16 A. Mark Schobel Ph sensitive compounds in taste masking within oral thin film strips
EP2512460A4 (en) * 2009-12-18 2015-01-21 Exodos Life Sciences Ltd Partnership METHOD AND COMPOSITIONS FOR STABLE LIQUID ACTIVE FORMULATIONS
US9053364B2 (en) 2012-10-30 2015-06-09 Authentiform, LLC Product, image, or document authentication, verification, and item identification
ES2761265T3 (es) 2013-03-15 2020-05-19 Aprecia Pharmaceuticals LLC Forma de dosificación de oxcarbazepina rápidamente dispersable
JP6466399B2 (ja) 2013-03-15 2019-02-06 アプレシア・ファーマスーティカルズ・カンパニー トピラマートの急速分散性の剤形
JP7418958B2 (ja) 2016-03-17 2024-01-22 チオジェネシス セラピューティクス， インコーポレイテッド システアミンの制御放出のための組成物及びシステアミン感受性障害の全身治療
KR102088315B1 (ko) 2017-10-23 2020-03-13 주식회사 웅진릴리에뜨 장용성 캡슐의 이취 마스킹 방법 및 이를 이용한 이취의 마스킹 처리가 이루어진 장용성 캡슐
RU2020127753A (ru) * 2018-01-22 2022-02-24 Джонсон энд Джонсон Консьюмер Инк. Перфорированные капсулы
EP3883546A1 (en) 2018-11-21 2021-09-29 Rosemont Pharmaceuticals Ltd Oral topiramate suspension formulations with extended shelf stability and enhanced bioavailability
CN117503701A (zh) * 2023-12-08 2024-02-06 斯坦德医药研发(江苏)有限公司 左氧氟沙星口服混悬液制剂及制剂制造方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62226926A (ja) 1986-03-27 1987-10-05 Teisan Seiyaku Kk 持続性複合顆粒剤
US5065094A (en) 1990-08-07 1991-11-12 Seagate Technology, Inc. Two terminal magnetoresistive sensor having DC blocking capacitor
FR2665635A1 (fr) * 1990-08-10 1992-02-14 Merck Sharp & Dohme Composition pharmaceutique fluide a base d'un complexe metallique et son procede de preparation.
CA2068402C (en) * 1991-06-14 1998-09-22 Michael R. Hoy Taste mask coatings for preparation of chewable pharmaceutical tablets
US5599556A (en) 1991-12-31 1997-02-04 Abbott Laboratories Prolamine coatings for taste masking
DE4200821A1 (de) * 1992-01-15 1993-07-22 Bayer Ag Geschmacksmaskierte pharmazeutische mittel
FR2694751B1 (fr) 1992-08-14 1994-11-25 Bouchara Sa Nouveaux dérivés sulfonamides, leurs procédés de préparation et les compositions en renfermant.
US5614222A (en) * 1994-10-25 1997-03-25 Kaplan; Milton R. Stable aqueous drug suspensions and methods for preparation thereof

Also Published As

Publication number Publication date
ES2219360T3 (es) 2004-12-01
IL147510A (en) 2007-06-03
PL197812B1 (pl) 2008-04-30
EP1194153B1 (en) 2004-05-06
CN1174740C (zh) 2004-11-10
US6482823B1 (en) 2002-11-19
PL352761A1 (en) 2003-09-08
HUP0201765A3 (en) 2004-05-28
KR20020029668A (ko) 2002-04-19
CA2377916C (en) 2008-03-11
EE200200012A (et) 2003-02-17
US6586012B2 (en) 2003-07-01
ATE265852T1 (de) 2004-05-15
IL147510A0 (en) 2002-08-14
KR100675809B1 (ko) 2007-02-01
MXPA02000331A (es) 2002-06-21
DK1194153T3 (da) 2004-08-02
US20030064107A1 (en) 2003-04-03
EE05147B1 (et) 2009-04-15
NZ516486A (en) 2003-10-31
SK322002A3 (en) 2003-02-04
EP1194153A1 (en) 2002-04-10
AU773555B2 (en) 2004-05-27
KR20020031382A (ko) 2002-05-01
HUP0201765A2 (hu) 2002-11-28
HRP20020119A2 (en) 2003-12-31
DE60010464T2 (de) 2005-05-12
PT1194153E (pt) 2004-09-30
CA2377916A1 (en) 2001-01-18
NO20020086D0 (no) 2002-01-08
DE60010464D1 (de) 2004-06-09
AR027179A1 (es) 2003-03-19
WO2001003698A1 (en) 2001-01-18
AU5880200A (en) 2001-01-30
NO20020086L (no) 2002-03-05
CN1360504A (zh) 2002-07-24
TR200200710T2 (tr) 2002-08-21
JP2003504335A (ja) 2003-02-04

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Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFIRO O PEDIDO DE ACORDO COM O(S) ARTIGO(S) 8O E 13 DA LPI

B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL.