BR0012401A - Preparação percutaneamente absorvìvel, e, composição aceleradora da absorção percutânea do medicamento ácido na forma de sal - Google Patents

Preparação percutaneamente absorvìvel, e, composição aceleradora da absorção percutânea do medicamento ácido na forma de sal

Info

Publication number
BR0012401A
BR0012401A BR0012401-0A BR0012401A BR0012401A BR 0012401 A BR0012401 A BR 0012401A BR 0012401 A BR0012401 A BR 0012401A BR 0012401 A BR0012401 A BR 0012401A
Authority
BR
Brazil
Prior art keywords
salt
percutaneous absorption
preparation
percutaneously absorbable
acid medicine
Prior art date
Application number
BR0012401-0A
Other languages
English (en)
Other versions
BRPI0012401B1 (pt
Inventor
Yasunori Takada
Koji Tanaka
Yasuhiro Ikeura
Original Assignee
Hisamitsu Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hisamitsu Pharmaceutical Co filed Critical Hisamitsu Pharmaceutical Co
Publication of BR0012401A publication Critical patent/BR0012401A/pt
Publication of BRPI0012401B1 publication Critical patent/BRPI0012401B1/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/186—Quaternary ammonium compounds, e.g. benzalkonium chloride or cetrimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7076—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising ingredients of undetermined constitution or reaction products thereof, e.g. rosin or other plant resins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pain & Pain Management (AREA)
  • Botany (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

"PREPARAçãO PERCUTANEAMENTE ABSORVìVEL, E, COMPOSIçãO ACELERADORA DA ABSORçãO PERCUTâNEA DO MEDICAMENTO áCIDO NA FORMA DE SAL". Preparações percutaneamente absorvíveis (preferivelmente não aquosas, particularmente emplastros ou ung³entos do tipo matriz), contendo os medicamentos ácido na forma de sal e caracterizadas por serem melhoradas na absorbilidade percutânea do medicamento pela incorporação de um sal de adição de uma substância básica a elas e por serem pouco irritantes à pele e um acelerador de absorção percutânea para os medicamentos ácidos na forma de sal, contendo um sal de adição de uma substância básica.
BRPI0012401A 1999-07-15 2000-07-11 preparação percutaneamente absorvível, e, composição aceleradora da absorção percutânea do medicamento ácido na forma de sal BRPI0012401B1 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP20134099 1999-07-15
PCT/JP2000/004609 WO2001005381A1 (en) 1999-07-15 2000-07-11 Percutaneously absorbable preparations

Publications (2)

Publication Number Publication Date
BR0012401A true BR0012401A (pt) 2002-05-21
BRPI0012401B1 BRPI0012401B1 (pt) 2016-09-27

Family

ID=16439413

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0012401A BRPI0012401B1 (pt) 1999-07-15 2000-07-11 preparação percutaneamente absorvível, e, composição aceleradora da absorção percutânea do medicamento ácido na forma de sal

Country Status (14)

Country Link
US (1) US7615237B1 (pt)
EP (1) EP1197209B1 (pt)
JP (1) JP4627945B2 (pt)
KR (1) KR100686527B1 (pt)
CN (1) CN1361686A (pt)
AT (1) ATE493121T1 (pt)
AU (1) AU771637B2 (pt)
BR (1) BRPI0012401B1 (pt)
CA (1) CA2379147C (pt)
DE (1) DE60045446D1 (pt)
DK (1) DK1197209T3 (pt)
ES (1) ES2356704T3 (pt)
TW (1) TWI234470B (pt)
WO (1) WO2001005381A1 (pt)

Families Citing this family (21)

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Publication number Priority date Publication date Assignee Title
JP4865958B2 (ja) * 2001-05-23 2012-02-01 株式会社トクホン 鎮痛抗炎症局所作用型の貼付剤
BRPI0210074B1 (pt) * 2001-05-31 2017-05-30 Hisamitsu Pharmaceutical Co emplastro de anti-inflamatórios não esteroidais percutaneamente absorvível, contendo sais de amônio, promotores de permeação e/ou agentes de solubilização em uma camada de substrato adesivo
TWI327074B (en) * 2003-05-07 2010-07-11 Hisamitsu Pharmaceutical Co Ultra violet shielding patch
WO2006051818A1 (ja) * 2004-11-10 2006-05-18 Hisamitsu Pharmaceutical Co., Inc. 外用製剤及び貼付剤
ES2437077T3 (es) * 2005-07-08 2014-01-08 Senju Pharmaceutical Co., Ltd. Preparado oftálmico de absorción percutánea que comprende olopatadina
CN100420726C (zh) * 2005-09-19 2008-09-24 上海安立霸电器有限公司 医用热熔压敏胶型基质及制备
JP4869697B2 (ja) * 2005-12-08 2012-02-08 日東電工株式会社 外用剤
EP1992363B1 (en) * 2006-02-28 2012-12-19 Hisamitsu Pharmaceutical Co., Inc. Transdermal absorption preparation
DE102006054732B4 (de) * 2006-11-21 2010-12-30 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches System mit Ionenpaar-Mikroreservoiren
CN101652478B (zh) * 2007-10-09 2013-03-27 爱科来株式会社 免疫相关基因的多态性的检测用探针及其用途
AU2008327436B2 (en) 2007-11-22 2013-09-05 Medrx Co., Ltd. External preparation composition comprising fatty acid-based ionic liquid as active ingredient
US20110319399A1 (en) * 2009-03-11 2011-12-29 Kowa Co., Ltd. External preparation containing analgesic/anti-inflammatory agent
CN102341122A (zh) * 2009-03-11 2012-02-01 兴和株式会社 含有镇痛-抗炎症剂的外用剂
JP6131523B2 (ja) * 2011-03-25 2017-05-24 大正製薬株式会社 ロキソプロフェン含有外用剤
JP5878715B2 (ja) * 2011-09-22 2016-03-08 久光製薬株式会社 貼付剤
US8617579B2 (en) * 2012-04-16 2013-12-31 Conopco, Inc. Pre-blended mixtures of specific naturally sourced liquid materials structured with naturally sourced high melting point structuring material
GB201301774D0 (en) * 2013-01-31 2013-03-20 Henry Richard Composition
EP2926832A1 (en) * 2014-03-31 2015-10-07 Sanovel Ilac Sanayi ve Ticaret A.S. Pharmaceutical formulations of loxoprofen for topical use
CN104288167B (zh) * 2014-10-29 2017-08-25 马应龙药业集团股份有限公司 一种治疗痔疮的七叶皂苷钠制剂及其制备方法
CN107921141A (zh) * 2015-08-27 2018-04-17 东洋油墨Sc控股株式会社 贴剂
CN105693556A (zh) * 2016-03-01 2016-06-22 巴斯特医药科技（常州）有限公司 卡巴拉汀酒石酸盐的转化方法及其产物制成的贴片

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Also Published As

Publication number Publication date
DE60045446D1 (de) 2011-02-10
ES2356704T3 (es) 2011-04-12
CA2379147A1 (en) 2001-01-25
KR20020015342A (ko) 2002-02-27
US7615237B1 (en) 2009-11-10
KR100686527B1 (ko) 2007-02-27
CN1361686A (zh) 2002-07-31
CA2379147C (en) 2009-09-01
EP1197209A4 (en) 2005-01-05
AU5852100A (en) 2001-02-05
EP1197209A1 (en) 2002-04-17
JP4627945B2 (ja) 2011-02-09
DK1197209T3 (da) 2011-04-04
AU771637B2 (en) 2004-04-01
EP1197209B1 (en) 2010-12-29
TWI234470B (en) 2005-06-21
WO2001005381A1 (en) 2001-01-25
ATE493121T1 (de) 2011-01-15
BRPI0012401B1 (pt) 2016-09-27

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Legal Events

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B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
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B12B Appeal against refusal [chapter 12.2 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

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B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 27/09/2016, OBSERVADAS AS CONDICOES LEGAIS.

B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

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B24J Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)

Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2628 DE 18-05-2021 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.