BR0015826A - Derivados de benzotiadiazinas, seu processo de preparação e as composições farmacêuticas que os contêm - Google Patents

Derivados de benzotiadiazinas, seu processo de preparação e as composições farmacêuticas que os contêm

Info

Publication number
BR0015826A
BR0015826A BR0015826-7A BR0015826A BR0015826A BR 0015826 A BR0015826 A BR 0015826A BR 0015826 A BR0015826 A BR 0015826A BR 0015826 A BR0015826 A BR 0015826A
Authority
BR
Brazil
Prior art keywords
pharmaceutical compositions
preparation process
compositions containing
benzothiadiazine derivatives
derivatives
Prior art date
Application number
BR0015826-7A
Other languages
English (en)
Inventor
Bernard Pirotte
Pascal De Tullio
Stephane Boverie
Isabelle Kempen
Pierre Lestage
Original Assignee
Servier Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Servier Lab filed Critical Servier Lab
Publication of BR0015826A publication Critical patent/BR0015826A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/15—Six-membered rings
    • C07D285/16—Thiadiazines; Hydrogenated thiadiazines
    • C07D285/18—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines
    • C07D285/20—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines condensed with carbocyclic rings or ring systems
    • C07D285/22—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D285/24—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with oxygen atoms directly attached to the ring sulfur atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)

Abstract

"DERIVADOS DE BENZOTIADIAZINAS, SEU PROCESSO DE PREPARAçãO E AS COMPOSIçõES FARMACêUTICAS QUE OS CONTêM". Composto de fórmula (I) na qual X representa um átomo de flúor, de bromo ou de iodo ou um grupamento metila, R~ 1~ e R~ 2~, idênticos ou diferentes, representam cada um deles um átomo de hidrogênio ou um grupamento alquila, seus isómeros quando eles existem, assim como seus sais de adição a um ácido farmaceuticamente aceitável.
BR0015826-7A 1999-11-30 2000-11-28 Derivados de benzotiadiazinas, seu processo de preparação e as composições farmacêuticas que os contêm BR0015826A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9915034A FR2801587B1 (fr) 1999-11-30 1999-11-30 Nouveaux derives de benzothiadiazines, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
PCT/FR2000/003313 WO2001040210A1 (fr) 1999-11-30 2000-11-28 Nouveaux derives de benzothiadiazines, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
BR0015826A true BR0015826A (pt) 2002-07-30

Family

ID=9552685

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0015826-7A BR0015826A (pt) 1999-11-30 2000-11-28 Derivados de benzotiadiazinas, seu processo de preparação e as composições farmacêuticas que os contêm

Country Status (24)

Country Link
US (1) US6894043B1 (pt)
EP (1) EP1233953B1 (pt)
JP (1) JP2003515599A (pt)
KR (1) KR100477385B1 (pt)
CN (1) CN1162414C (pt)
AT (1) ATE240306T1 (pt)
AU (1) AU772641B2 (pt)
BR (1) BR0015826A (pt)
CA (1) CA2392929A1 (pt)
DE (1) DE60002755T2 (pt)
DK (1) DK1233953T3 (pt)
EA (1) EA004053B1 (pt)
ES (1) ES2199188T3 (pt)
FR (1) FR2801587B1 (pt)
HK (1) HK1052697B (pt)
HU (1) HUP0204154A3 (pt)
MX (1) MXPA02004593A (pt)
NO (1) NO20022552L (pt)
NZ (1) NZ519271A (pt)
PL (1) PL355722A1 (pt)
PT (1) PT1233953E (pt)
SI (1) SI1233953T1 (pt)
WO (1) WO2001040210A1 (pt)
ZA (1) ZA200203305B (pt)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2833950B1 (fr) 2001-12-21 2005-12-16 Servier Lab Nouveaux derives de benzothiazine et de benzothiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2854634B1 (fr) * 2003-05-05 2005-07-08 Servier Lab Nouveaux derives de thiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2865474B1 (fr) * 2004-01-26 2008-06-13 Servier Lab Nouveaux derives de benzothiazines fluorees, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
JP2008510835A (ja) * 2004-08-25 2008-04-10 エッセンシャリス，インク． カリウムａｔｐチャンネル開放因子の製剤処方、及びその使用
US20060063707A1 (en) * 2004-09-17 2006-03-23 Lifelike Biomatic, Inc. Compositions for enhancing memory and methods therefor
FR2877338B1 (fr) * 2004-11-03 2007-01-26 Servier Lab Nouveaux derives de benzothiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2877342B1 (fr) * 2004-11-03 2007-01-26 Servier Lab Nouveaux derives de benzothiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2879201B1 (fr) * 2004-12-10 2007-02-16 Servier Lab Nouveaux derives de benzothiazine et benzothiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
WO2007081521A2 (en) 2006-01-05 2007-07-19 Essentialis, Inc. Salts of potassium atp channel openers and uses thereof
KR100787130B1 (ko) * 2006-03-23 2007-12-21 한국화학연구원 신규의 치환된 1,1-다이옥소-벤조[1,2,4]티아디아진-3-온, 이의 제조방법 및 이를 포함하는 약학적 조성물
CN101795691A (zh) * 2007-07-02 2010-08-04 伊森舍丽斯有限公司 钾atp通道开放剂的盐及其用途
US20110218190A1 (en) * 2008-11-10 2011-09-08 The Regents Of The University Of California Therapeutic uses of ampa receptor modulators for treatment of motor dysfunction
WO2012020848A1 (en) 2010-08-10 2012-02-16 Takeda Pharmaceutical Company Limited Heterocyclic compound and use thereof
CN102600171A (zh) * 2010-10-27 2012-07-25 北京理工大学 一类苯并噻二嗪和吡啶并噻二嗪衍生物作为醛糖还原酶抑制剂的结构、合成方法及用途
JP6649377B2 (ja) * 2014-11-03 2020-02-19 ザ ジェネラル ホスピタル コーポレイション ミクロ流体装置による粒子の複合式分類および濃縮
TWI873185B (zh) 2019-09-16 2025-02-21 日商武田藥品工業股份有限公司 唑稠合之嗒-3(2h)-酮衍生物
CN111518058B (zh) * 2020-05-29 2021-03-09 四川大学华西医院 一种噁噻嗪类化合物及其用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2690160A1 (fr) * 1992-04-15 1993-10-22 Rhone Poulenc Rorer Sa Application de dérivés d'acide 2H-1,2,4-benzothiadiazine-1,1-dioxyde-3-carboxylique à la préparation de médicaments, les produits nouveaux, leur préparation et les médicaments les contenant.
HUT70955A (en) * 1992-04-15 1995-11-28 Rhone Poulenc Rorer Sa 3,4-dihydro-1,1-dioxo-2h-1,2,4-benzothiadiazine-3-carboxylic acid derivatives, preparation thereof and drugs containing same
FR2710062B1 (fr) * 1993-09-17 1995-12-01 Rhone Poulenc Rorer Sa Dérivés d'acide 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxyde-3-carboxylique, leur préparation et les médicaments les contenant.
AU4345297A (en) * 1996-09-17 1998-04-14 Regents Of The University Of California, The Benzothiadiazide derivatives and their use as allosteric up-modulators of the ampa receptor

Also Published As

Publication number Publication date
FR2801587A1 (fr) 2001-06-01
CN1402717A (zh) 2003-03-12
AU1870401A (en) 2001-06-12
DE60002755D1 (de) 2003-06-18
KR20020058047A (ko) 2002-07-12
NO20022552D0 (no) 2002-05-29
EA004053B1 (ru) 2003-12-25
HUP0204154A2 (hu) 2003-03-28
DK1233953T3 (da) 2003-08-11
EP1233953A1 (fr) 2002-08-28
FR2801587B1 (fr) 2002-01-11
US6894043B1 (en) 2005-05-17
EA200200489A1 (ru) 2002-10-31
DE60002755T2 (de) 2004-04-29
JP2003515599A (ja) 2003-05-07
HUP0204154A3 (en) 2006-01-30
ATE240306T1 (de) 2003-05-15
HK1052697B (zh) 2005-02-08
NZ519271A (en) 2004-02-27
EP1233953B1 (fr) 2003-05-14
HK1052697A1 (en) 2003-09-26
PL355722A1 (en) 2004-05-17
AU772641B2 (en) 2004-05-06
WO2001040210A1 (fr) 2001-06-07
SI1233953T1 (en) 2003-10-31
NO20022552L (no) 2002-07-11
PT1233953E (pt) 2003-08-29
ZA200203305B (en) 2003-06-25
KR100477385B1 (ko) 2005-03-17
ES2199188T3 (es) 2004-02-16
CN1162414C (zh) 2004-08-18
MXPA02004593A (es) 2002-09-02
CA2392929A1 (fr) 2001-06-07

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 6A,7A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO PUBLICADO NA RPI 1962 DE 12/08/2008.