BR0016136A - Processos para a preparação do (s) -enanciÈmero de um composto, e de um composto, e, composto - Google Patents
Processos para a preparação do (s) -enanciÈmero de um composto, e de um composto, e, compostoInfo
- Publication number
- BR0016136A BR0016136A BR0016136-5A BR0016136A BR0016136A BR 0016136 A BR0016136 A BR 0016136A BR 0016136 A BR0016136 A BR 0016136A BR 0016136 A BR0016136 A BR 0016136A
- Authority
- BR
- Brazil
- Prior art keywords
- compound
- preparation
- finance
- processes
- useful
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 3
- -1 and Chemical class 0.000 title 1
- 208000031773 Insulin resistance syndrome Diseases 0.000 abstract 2
- FMJUDUJLTNVWCH-UHFFFAOYSA-N 2-ethoxy-3-(4-hydroxyphenyl)propanoic acid Chemical class CCOC(C(O)=O)CC1=CC=C(O)C=C1 FMJUDUJLTNVWCH-UHFFFAOYSA-N 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 230000000144 pharmacologic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
- C07C69/734—Ethers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
- C07C51/377—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by splitting-off hydrogen or functional groups; by hydrogenolysis of functional groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/41—Preparation of salts of carboxylic acids
- C07C51/412—Preparation of salts of carboxylic acids by conversion of the acids, their salts, esters or anhydrides with the same carboxylic acid part
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Separation By Low-Temperature Treatments (AREA)
- Electrical Discharge Machining, Electrochemical Machining, And Combined Machining (AREA)
- Crystals, And After-Treatments Of Crystals (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
"PROCESSOS PARA A PREPARAçãO DO (S)-ENANCIÈMERO DE UM COMPOSTO, E DE UM COMPOSTO, E, COMPOSTO". A presente invenção refere-se aos novos métodos de resolução, que são úteis na preparação de intermediários enanciomericamente enriquecidos que por sua vez são úteis na preparação de compostos com um efeito farmacológico sobre a síndrome da resistência à insulina (IRS, insulin resistance syndrome). E um tal processo que a presente invenção intenciona definir, e mais particularmente para a preparação do (S)-enanciómero de certos ácidos 2-etóxi-3-(4-hidroxifenil)propanóicos e seus derivados.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9904415A SE9904415D0 (sv) | 1999-12-03 | 1999-12-03 | New process |
| PCT/SE2000/002382 WO2001040159A1 (en) | 1999-12-03 | 2000-11-29 | New process |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0016136A true BR0016136A (pt) | 2002-08-20 |
Family
ID=20417980
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0016136-5A BR0016136A (pt) | 1999-12-03 | 2000-11-29 | Processos para a preparação do (s) -enanciÈmero de um composto, e de um composto, e, composto |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US7002037B2 (pt) |
| EP (1) | EP1237838B1 (pt) |
| JP (1) | JP2003515578A (pt) |
| KR (1) | KR100794091B1 (pt) |
| CN (1) | CN1213016C (pt) |
| AT (1) | ATE264287T1 (pt) |
| AU (1) | AU765938B2 (pt) |
| BR (1) | BR0016136A (pt) |
| CA (1) | CA2392032C (pt) |
| DE (1) | DE60009953T2 (pt) |
| DK (1) | DK1237838T3 (pt) |
| ES (1) | ES2218258T3 (pt) |
| IL (2) | IL149576A0 (pt) |
| MX (1) | MXPA02005321A (pt) |
| NO (1) | NO20022604L (pt) |
| PT (1) | PT1237838E (pt) |
| SE (1) | SE9904415D0 (pt) |
| TR (1) | TR200401717T4 (pt) |
| WO (1) | WO2001040159A1 (pt) |
| ZA (1) | ZA200203705B (pt) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1280574A (zh) | 1997-10-27 | 2001-01-17 | 雷迪研究基金会 | 新的杂环化合物及其在医药中的应用、它们的制备方法和含有它们的药物组合物 |
| BR9812770A (pt) | 1997-10-27 | 2000-12-12 | Reddy Research Foundation | Compostos bicìclicos, processo para seu preparo e composições farmacêuticas contendo os mesmos |
| US6369067B1 (en) | 1997-10-27 | 2002-04-09 | Dr. Reddy's Research Foundation | Monocyclic compounds and their use in medicine: process for their preparation and pharmaceutical compositions containing them |
| MXPA00004036A (es) | 1997-10-27 | 2006-05-24 | Reddys Lab Ltd Dr | Compuestos triciclicos novedosos y su uso en medicina; proceso para su preparacion y composiciones farmaceuticas que los contienen.. |
| US6440961B1 (en) | 1997-10-27 | 2002-08-27 | Dr. Reddy's Research Foundation | Tricyclic compounds and their use in medicine: process for their preparation and pharmaceutical compositions containing them |
| US6531596B1 (en) | 1998-10-29 | 2003-03-11 | Dr. Reddy's Laboratories Ltd. | Process for the preparation of new antidiabetic agents |
| JP2002528535A (ja) | 1998-10-29 | 2002-09-03 | ドクター・レディーズ・リサーチ・ファウンデーション | 新規抗糖尿病剤製造の改良方法 |
| SE9904415D0 (sv) * | 1999-12-03 | 1999-12-03 | Astra Ab | New process |
| US6897199B2 (en) | 2001-02-05 | 2005-05-24 | Dr. Reddy's Laboratories Ltd. | Pharmaceutically acceptable salts of phenoxazine and phenothiazine compounds |
| US6962940B2 (en) | 2002-03-20 | 2005-11-08 | Celgene Corporation | (+)-2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione: methods of using and compositions thereof |
| US20070142472A1 (en) * | 2003-11-27 | 2007-06-21 | Tohru Yokozawa | Process for producing optically active 3-(4-hydroxyphenyl)proprionic acids |
| DE102004035034A1 (de) * | 2004-07-20 | 2006-02-16 | Degussa Ag | Racematspaltung von p-Hydroxyphenyl-2-alkoxy-propionsäuren |
| ITMI20061297A1 (it) * | 2006-07-04 | 2008-01-05 | Laboratorio Chimico Int Spa | Procedimento per la preparazione della'acido (r)-(-)-3-(carbamoilmetil)-5-metilesanoico e del pregabalin e intermedi di sintesi |
| RU2480453C2 (ru) | 2007-03-08 | 2013-04-27 | Альбирео Аб | Новые соединения |
| JP5416774B2 (ja) * | 2008-08-25 | 2014-02-12 | デュポン・エレクトロニック・ポリマーズ・エル・ピー | 新規プロパノエート及びその製造法 |
| CN101838195B (zh) * | 2009-03-17 | 2014-08-13 | 天士力制药集团股份有限公司 | 光学纯的β-3,4-二羟基苯基乳酸的化学拆分制备法 |
| CN104447294A (zh) * | 2014-11-24 | 2015-03-25 | 苏州乔纳森新材料科技有限公司 | 一种3-环己烯-1-甲酸的手性拆分方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5306725A (en) | 1989-03-01 | 1994-04-26 | Katayama Chemical Inc. | Stabilized isothiazolone liquid formulation |
| CZ1095A3 (en) | 1992-07-03 | 1995-10-18 | Smithkline Beecham Plc | Heterocyclic compounds, process of their preparation, their use for the preparation of a pharmaceutical preparation and the pharmaceutical composition containing thereof |
| US5232945A (en) | 1992-07-20 | 1993-08-03 | Pfizer Inc. | 3-aryl-2-hydroxypropionic acid derivatives and analogs as antihypertensives |
| GB9604242D0 (en) * | 1996-02-28 | 1996-05-01 | Glaxo Wellcome Inc | Chemical compounds |
| MXPA00004036A (es) | 1997-10-27 | 2006-05-24 | Reddys Lab Ltd Dr | Compuestos triciclicos novedosos y su uso en medicina; proceso para su preparacion y composiciones farmaceuticas que los contienen.. |
| SE9801992D0 (sv) | 1998-06-04 | 1998-06-04 | Astra Ab | New 3-aryl-2-hydroxypropionic acid derivative I |
| SE9801990D0 (sv) * | 1998-06-04 | 1998-06-04 | Astra Ab | New 3-aryl propionic acid derivatives and analogs |
| MA26634A1 (fr) | 1998-06-04 | 2004-12-20 | Astra Ab | Nouveaux derives de l'acide 3-aryl propionique et analogues |
| SE9904415D0 (sv) * | 1999-12-03 | 1999-12-03 | Astra Ab | New process |
-
1999
- 1999-12-03 SE SE9904415A patent/SE9904415D0/xx unknown
-
2000
- 2000-11-29 DE DE60009953T patent/DE60009953T2/de not_active Expired - Fee Related
- 2000-11-29 ES ES00983617T patent/ES2218258T3/es not_active Expired - Lifetime
- 2000-11-29 IL IL14957600A patent/IL149576A0/xx active IP Right Grant
- 2000-11-29 DK DK00983617T patent/DK1237838T3/da active
- 2000-11-29 CN CNB008187037A patent/CN1213016C/zh not_active Expired - Fee Related
- 2000-11-29 KR KR1020027007070A patent/KR100794091B1/ko not_active Expired - Fee Related
- 2000-11-29 AT AT00983617T patent/ATE264287T1/de not_active IP Right Cessation
- 2000-11-29 CA CA002392032A patent/CA2392032C/en not_active Expired - Fee Related
- 2000-11-29 WO PCT/SE2000/002382 patent/WO2001040159A1/en not_active Ceased
- 2000-11-29 MX MXPA02005321A patent/MXPA02005321A/es active IP Right Grant
- 2000-11-29 AU AU20349/01A patent/AU765938B2/en not_active Ceased
- 2000-11-29 TR TR2004/01717T patent/TR200401717T4/xx unknown
- 2000-11-29 JP JP2001541849A patent/JP2003515578A/ja not_active Withdrawn
- 2000-11-29 US US10/148,818 patent/US7002037B2/en not_active Expired - Fee Related
- 2000-11-29 PT PT00983617T patent/PT1237838E/pt unknown
- 2000-11-29 EP EP00983617A patent/EP1237838B1/en not_active Expired - Lifetime
- 2000-11-29 BR BR0016136-5A patent/BR0016136A/pt not_active Application Discontinuation
-
2002
- 2002-05-09 IL IL149576A patent/IL149576A/en not_active IP Right Cessation
- 2002-05-09 ZA ZA200203705A patent/ZA200203705B/xx unknown
- 2002-05-31 NO NO20022604A patent/NO20022604L/no not_active Application Discontinuation
-
2005
- 2005-11-18 US US11/282,247 patent/US20060069283A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| MXPA02005321A (es) | 2002-12-06 |
| CN1433393A (zh) | 2003-07-30 |
| US20060069283A1 (en) | 2006-03-30 |
| AU765938B2 (en) | 2003-10-02 |
| US7002037B2 (en) | 2006-02-21 |
| AU2034901A (en) | 2001-06-12 |
| ZA200203705B (en) | 2003-10-29 |
| ATE264287T1 (de) | 2004-04-15 |
| NO20022604D0 (no) | 2002-05-31 |
| ES2218258T3 (es) | 2004-11-16 |
| JP2003515578A (ja) | 2003-05-07 |
| EP1237838B1 (en) | 2004-04-14 |
| CN1213016C (zh) | 2005-08-03 |
| SE9904415D0 (sv) | 1999-12-03 |
| CA2392032C (en) | 2008-10-28 |
| DE60009953D1 (de) | 2004-05-19 |
| KR20020058071A (ko) | 2002-07-12 |
| IL149576A0 (en) | 2002-11-10 |
| KR100794091B1 (ko) | 2008-01-10 |
| IL149576A (en) | 2007-09-20 |
| EP1237838A1 (en) | 2002-09-11 |
| US20030139474A1 (en) | 2003-07-24 |
| PT1237838E (pt) | 2004-08-31 |
| DK1237838T3 (da) | 2004-07-12 |
| DE60009953T2 (de) | 2005-03-31 |
| NO20022604L (no) | 2002-07-11 |
| TR200401717T4 (tr) | 2004-09-21 |
| CA2392032A1 (en) | 2001-06-07 |
| WO2001040159A1 (en) | 2001-06-07 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BR0016136A (pt) | Processos para a preparação do (s) -enanciÈmero de um composto, e de um composto, e, composto | |
| CY1125885T1 (el) | Τροποποιημενο πολυπεπτιδιο παραγοντα ix, οι χρησεις του και μια μεθοδος για την παραγωγη του | |
| NO20071498L (no) | Substituerte acylhydroksamsyrer samt fremgangsmate for a redusere TNFa-nivaet | |
| GT200100183A (es) | Derivados de quinolina y quinazolina. | |
| BRPI0513029A (pt) | método para produzir uma proteìna de eritropoietina carbamilada, proteìna de eritropoietina carbamilada, composto, composição farmacêutica, métodos de tratamento de uma doença ou condição crÈnica, sub-crÈnica e aguda e de tratamento de uma doença do sistema nervoso central ou sistema nervoso periférico, e, uso de um composto | |
| BRPI0413490A (pt) | novos compostos | |
| BRPI0415288A (pt) | composto, composição farmacêutica, método para tratar ou prevenir doenças, e, método para preparar o composto | |
| BR0309659A (pt) | Método para produzir vìrus de uma cultura de células, composição, e, método para produzir reovìrus infeccioso | |
| ATE444746T1 (de) | Eine herstellungsmethode von entacapon- enthaltenden granulaten für orale dosierformen | |
| CY1116498T1 (el) | Διεργασια για την παρασκευη (r)-(-)-3-(καρβαμοϋλομεθυλ)-5-μεθυλεξανοϊκου οξεος και πρεγκαμπαλινης και συνθεση ενδιαμεσων | |
| BRPI0518647A2 (pt) | processo para a produÇço de um composto, e, composto | |
| AR052879A1 (es) | Procedimiento para preparar derivados de beta aminoacidos quirales por hidrogenacion asimetrica | |
| HUP0203914A2 (en) | High order nucleic acid based structures | |
| BR0015202A (pt) | Processo para a purificação de uma solução contendo aminoácido por meio de eletrodiálise, e processo integrado para a produção de um aminoácido livre | |
| BR0012631A (pt) | Processo para a preparação de compostos de amina | |
| DK0748326T3 (da) | Optisk aktive diphosphiner og fremstilling heraf ved spaltning af den racemiske blanding | |
| BR0315836A (pt) | Derivados de [6,7-dihidro-5h-imidazol[1,2-alfa]imadazol-3-sulfonila mino]-propionamida, composição farmacêutica, uso do mesmo, bem como processo para sua preparação | |
| BR0001342A (pt) | Processo para a produção de l-aminoácidos por meio de fermentação usando bactérias corineformes | |
| BR9808500A (pt) | Composições de beta cetoésteres e método de produção | |
| DE502005011199D1 (de) | Herstellung eines von willenbrand faktor-präparates mit hoher spezifischer aktivität | |
| EA200801348A1 (ru) | Способ получения промежуточных соединений хлорамфеникола или его аналогов | |
| Kemperman et al. | Clathration-induced asymmetric transformation of cefadroxil | |
| EA200700332A1 (ru) | Новые полиморфы атовахона и способ их получения | |
| BR0212272A (pt) | Processo enzimático para a resolução enantiomérica de aminoácidos | |
| WO2004081220A3 (en) | A process for enzymatically resolving an enantiomeric mixture of alpha-hydroxy acids |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
| B11B | Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements |