BR0108087A - Método e composições para o tratamento de uma doença inflamatória - Google Patents

Método e composições para o tratamento de uma doença inflamatória

Info

Publication number
BR0108087A
BR0108087A BR0108087-3A BR0108087A BR0108087A BR 0108087 A BR0108087 A BR 0108087A BR 0108087 A BR0108087 A BR 0108087A BR 0108087 A BR0108087 A BR 0108087A
Authority
BR
Brazil
Prior art keywords
treatment
inflammatory disease
compositions
inhibitor
phosphodistearase
Prior art date
Application number
BR0108087-3A
Other languages
English (en)
Inventor
Elizabeth T Keating
James M Kanagy
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of BR0108087A publication Critical patent/BR0108087A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

"MéTODO E COMPOSIçõES PARA O TRATAMENTO DE UMA DOENçA INFLAMATóRIA". Essa invenção se refere ao tratamento de uma doença inflamatória mediante a administração de um inibidor de fosfodiestearase 4 em combinação com um inibidor da síntese de prostaglandina, as NSAIDs sendo exemplares.
BR0108087-3A 2000-02-08 2001-02-08 Método e composições para o tratamento de uma doença inflamatória BR0108087A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US18087900P 2000-02-08 2000-02-08
PCT/US2001/003972 WO2001058441A1 (en) 2000-02-08 2001-02-08 Method and compositions for treating an inflammatory disease

Publications (1)

Publication Number Publication Date
BR0108087A true BR0108087A (pt) 2002-10-29

Family

ID=22662062

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0108087-3A BR0108087A (pt) 2000-02-08 2001-02-08 Método e composições para o tratamento de uma doença inflamatória

Country Status (16)

Country Link
EP (1) EP1253919A4 (pt)
JP (1) JP2003522142A (pt)
KR (1) KR20020073577A (pt)
CN (1) CN1398181A (pt)
AU (1) AU7205701A (pt)
BR (1) BR0108087A (pt)
CA (1) CA2398184A1 (pt)
CZ (1) CZ20022682A3 (pt)
HK (1) HK1051319A1 (pt)
HU (1) HUP0300689A3 (pt)
IL (1) IL150963A0 (pt)
MX (1) MXPA02007688A (pt)
NO (1) NO20023737L (pt)
PL (1) PL356447A1 (pt)
WO (1) WO2001058441A1 (pt)
ZA (1) ZA200206252B (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7338971B2 (en) * 2001-08-30 2008-03-04 El-Naggar Mawaheb M Treatment of inflammatory, cancer, and thrombosis disorders
MXPA04002562A (es) * 2001-09-19 2004-05-31 Altana Pharma Ag Combinacion de un pde-4 y nsaid.
US20040259863A1 (en) * 2001-10-31 2004-12-23 Hans-Michael Eggenweiler Type 4 phosphodiesterase inhibitors and uses thereof
WO2004098605A1 (en) * 2003-05-12 2004-11-18 Altana Pharma Ag Pharmaceutical composition comprising a pde4 inhibitor and il-1 trap
WO2005020926A2 (en) * 2003-08-28 2005-03-10 Pharmacia Corporation Treatment or prevention of vascular disorders with cox-2 inhibitors in combination with cyclic amp-specific phosphodiesterase inhibitors
CA2753597A1 (en) * 2009-02-27 2010-09-02 Boehringer Ingelheim International Gmbh Drug combinations containing pde4-inhibitors and nsaids
CA2753604A1 (en) * 2009-02-27 2010-09-02 Boehringer Ingelheim International Gmbh Drug combinations containing pde4-inhibitors and nsaids
RS55856B1 (sr) 2010-07-14 2017-08-31 Novartis Ag Heterociklična jedinjenja agonisti ip receptora
CN104053659B (zh) 2012-01-13 2016-11-09 诺华股份有限公司 用于治疗肺动脉高压(pah)及相关病症的作为ip 受体激动剂的稠合的吡咯类
EP2956455B1 (en) 2013-02-13 2017-05-17 Novartis AG Ip receptor agonist heterocyclic compounds

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4061779A (en) * 1973-09-11 1977-12-06 Beecham Group Limited Naphthalene derivatives having anti-inflammatory activity
GB9108128D0 (en) * 1991-04-15 1991-06-05 Zambeletti Spa L Novel formulation
HU225869B1 (en) * 1992-04-02 2007-11-28 Smithkline Beecham Corp Compounds with antiallergic and antiinflammatory activity and pharmaceutical compns. contg. them
US6005118A (en) * 1996-05-03 1999-12-21 Caron; Stephane Methods of preparing 4-cyano-4 (substituted indazole) cyclohexane-carboxylic acids useful as PDE4 inhibitors
FR2753706B1 (fr) * 1996-09-20 1998-10-30 Nouvelles amines cycliques n-substituees, leur procede de preparation et les compositions pharmaceutiques les renfermant

Also Published As

Publication number Publication date
CN1398181A (zh) 2003-02-19
PL356447A1 (en) 2004-06-28
NO20023737D0 (no) 2002-08-07
MXPA02007688A (es) 2002-12-13
KR20020073577A (ko) 2002-09-27
HUP0300689A2 (hu) 2003-07-28
NO20023737L (no) 2002-09-27
CA2398184A1 (en) 2001-08-16
HUP0300689A3 (en) 2003-09-29
WO2001058441A1 (en) 2001-08-16
CZ20022682A3 (cs) 2003-09-17
EP1253919A4 (en) 2007-03-14
EP1253919A1 (en) 2002-11-06
AU7205701A (en) 2001-08-20
HK1051319A1 (zh) 2003-08-01
JP2003522142A (ja) 2003-07-22
IL150963A0 (en) 2003-02-12
ZA200206252B (en) 2003-08-26

Similar Documents

Publication Publication Date Title
DE602004008098D1 (de) Substituierte 2h-ä1,2,4ütriazoloä4,3-aüpyrazine als gsk-3-inhibitoren
DZ3402A1 (fr) Cyclopentanoindoles, compositions contenant ces composes et methodes de traitement
NO20025601D0 (no) Arylmetylaminderivater for anvendelse som tryptaseinhibitorer
HRP20050663A2 (en) Malonamide derivatives as gamma-secretase inhibitors
BR0317822A (pt) Composição fluoroquìmica
BR0010555A (pt) Inibidores de neuraminidases
MA30602B1 (fr) Modulateurs du metabolisme, et traitement de troubles au moyen de ces modulateurs
BR0316532A (pt) Composições farmacêuticas compreendendo, um composto de droga básico, respectivamente um ácido, um tensoativo e um ácido solúvel em água fisiologicamente tolerável, respectivamente, uma base
UY26815A1 (es) Métodos para tratar enfermedades reumáticas al usar una molécula ctla4 soluble
BRPI0509505A (pt) método e kit útil para branqueamento de uma superfìcie dental
SE0301886D0 (sv) New use V
CL2007000789A1 (es) Compuestos derivados de malonamida, inhibidores de la gamma-secretasa; proceso de preparacion; composicion farmaceutica; y su uso en el tratamiento de la enfermedad de alzheimer.
EA201200968A1 (ru) Применение транс-кломифена для предотвращения или лечения диабета 2 типа у мужчин
ECSP067110A (es) Derivados de 2-carbamida-4-feniltiazol, su preparación y su aplicación en terapéutica
ATE554084T1 (de) N-hydroxyacrylamidverbindungen
BRPI0519106A2 (pt) compostos, uso destes, processo para sua fabricaÇço, composiÇÕes farmacÊuticas, mÉtodo para o tratamento e/ou profilaxia de doenÇas que sço associadas com a dpp-iv
AR109263A2 (es) Composición que comprende moxidectina
IS8485A (is) Notkun á setnum 2-amínótetralínum í fyrirbyggjandi meðferð á Parkinsons-veiki
DK1296972T3 (da) Arylmethylamin-derivater til anvendelse som tryptaseinhibitorer
AR050717A1 (es) Composiciones farmaceuticas
PA8542901A1 (es) Uso de (z)-2-ciano-3-hidroxi-but-2-acido enoico-(4-trifluorometilfenil)-amida para tratar la esclerosis multiple
DE60227244D1 (de) Erythropoietin reduziert die chemotherapiebedingte in-vivo-toxizität
BR0305708A (pt) Derivados de benzimidazol para o tratamento de disfunção sexual
PA8531701A1 (es) Derivados de pirimidina
ATE308540T1 (de) Antithrombosemittel

Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]