BR0108981A - Combinações de substâncias ativas antiinfecciosas e seu emprego para o tratamento tópico de doenças por fungos das unhas dos pé e das mãos - Google Patents

Combinações de substâncias ativas antiinfecciosas e seu emprego para o tratamento tópico de doenças por fungos das unhas dos pé e das mãos

Info

Publication number
BR0108981A
BR0108981A BR0108981-1A BR0108981A BR0108981A BR 0108981 A BR0108981 A BR 0108981A BR 0108981 A BR0108981 A BR 0108981A BR 0108981 A BR0108981 A BR 0108981A
Authority
BR
Brazil
Prior art keywords
diseases
active substances
topical
combination
toenail
Prior art date
Application number
BR0108981-1A
Other languages
English (en)
Other versions
BR0108981B1 (pt
BRPI0108981B8 (pt
Inventor
Manfred Bohn
Karl Theodor Kraemer
Original Assignee
Aventis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Gmbh filed Critical Aventis Pharma Gmbh
Publication of BR0108981A publication Critical patent/BR0108981A/pt
Publication of BR0108981B1 publication Critical patent/BR0108981B1/pt
Publication of BRPI0108981B8 publication Critical patent/BRPI0108981B8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4196—1,2,4-Triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02—Local antiseptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Cosmetics (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

"COMBINAçõES DE SUBSTâNCIAS ATIVAS ANTIINFECCIOSAS E SEU EMPREGO PARA O TRATAMENTO TóPICO DE DOENçAS POR FUNGOS DAS UNHAS DOS PéS E DAS MãOS". A invenção refere-se a um preparado, contendo uma combinação de substância ativa de um antimicótico tópico e um sistêmico e uma base de laca fisiologicamente inofensiva prestam-se para o tratamento de onicomicoses. De preferência, são aplicados preparados de laca insolúveis na água e uma combinação de pelo menos um antimicótico sistêmico do grupo itraconazol, terbinafin e fluconazol ou seus sais com pelo menos um antimicótico tópico do grupo ciclopirox, 6-(2,4,4-trimetilpentil)-1-hidróxi-4-metil-2-(1H)-piridona, amorolfin e butenafin ou seus sais.
BRPI0108981A 2000-03-09 2001-02-28 preparado contendo combinações de substâncias ativas antimicóticas e um formador de película insolúvel em água BRPI0108981B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10011081A DE10011081A1 (de) 2000-03-09 2000-03-09 Antiinfektive Wirkstoffkombinationen und ihre Verwendung zur topischen Behandlung von Pilzerkrankungen der Fuß- und Fingernägel
DE10011081.9 2000-03-09
PCT/EP2001/002236 WO2001066145A1 (de) 2000-03-09 2001-02-28 Antiinfektive wirkstoffkombinationen und ihre verwendung zur topischen behandlung von pilzerkrankungen der fuss- und fingernägel

Publications (3)

Publication Number Publication Date
BR0108981A true BR0108981A (pt) 2003-06-03
BR0108981B1 BR0108981B1 (pt) 2014-01-07
BRPI0108981B8 BRPI0108981B8 (pt) 2021-05-25

Family

ID=7633836

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0108981A BRPI0108981B8 (pt) 2000-03-09 2001-02-28 preparado contendo combinações de substâncias ativas antimicóticas e um formador de película insolúvel em água

Country Status (29)

Country Link
US (2) US20010046478A1 (pt)
EP (1) EP1267932B1 (pt)
JP (1) JP4843176B2 (pt)
KR (1) KR100766738B1 (pt)
CN (1) CN1216642C (pt)
AT (1) ATE259660T1 (pt)
AU (2) AU2001246484B2 (pt)
BR (1) BRPI0108981B8 (pt)
CA (1) CA2402267C (pt)
CZ (1) CZ298718B6 (pt)
DE (2) DE10011081A1 (pt)
DK (1) DK1267932T3 (pt)
EE (1) EE04994B1 (pt)
ES (1) ES2211792T3 (pt)
HK (1) HK1054197B (pt)
HR (1) HRP20020731B1 (pt)
HU (1) HU228788B1 (pt)
IL (2) IL151519A0 (pt)
ME (2) MEP28808A (pt)
MX (1) MXPA02008292A (pt)
NO (1) NO330245B1 (pt)
NZ (1) NZ521226A (pt)
PL (1) PL200700B1 (pt)
PT (1) PT1267932E (pt)
RS (1) RS50450B (pt)
RU (1) RU2261701C2 (pt)
SK (1) SK287076B6 (pt)
WO (1) WO2001066145A1 (pt)
ZA (1) ZA200207213B (pt)

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KR101580077B1 (ko) * 2015-03-28 2015-12-24 한국콜마주식회사 시크로피록스 함유 네일락카 조성물
WO2017029387A1 (en) * 2015-08-20 2017-02-23 Galderma Sa Method of improving visual appearance of nails affected by onychomycosis
BR112018075998A2 (pt) * 2016-06-13 2019-04-02 Vyome Therapeutics Limited. composições antifúngicas sinérgicas e métodos das mesmas
WO2017216722A2 (en) * 2016-06-13 2017-12-21 Vyome Biosciences Pvt. Ltd. Synergistic antifungal compositions and methods thereof
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US20220211717A1 (en) * 2021-01-04 2022-07-07 Garry Alan Katz Topical treatment of fungal infections of the hair, skin, and nails
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Also Published As

Publication number Publication date
CZ20023001A3 (cs) 2002-11-13
CA2402267C (en) 2009-10-20
RS50450B (sr) 2010-03-02
HK1054197A1 (en) 2003-11-21
JP4843176B2 (ja) 2011-12-21
HRP20020731B1 (en) 2011-07-31
BR0108981B1 (pt) 2014-01-07
JP2003525910A (ja) 2003-09-02
WO2001066145A1 (de) 2001-09-13
DK1267932T3 (da) 2004-06-01
BRPI0108981B8 (pt) 2021-05-25
YU64702A (sh) 2005-09-19
EE200200482A (et) 2004-02-16
HUP0300135A3 (en) 2005-04-28
IL151519A0 (en) 2003-04-10
ES2211792T3 (es) 2004-07-16
HK1054197B (zh) 2005-12-16
EE04994B1 (et) 2008-04-15
DE10011081A1 (de) 2001-09-13
PL200700B1 (pl) 2009-01-30
HU228788B1 (en) 2013-05-28
PT1267932E (pt) 2004-07-30
EP1267932B1 (de) 2004-02-18
KR100766738B1 (ko) 2007-10-15
AU2001246484B2 (en) 2005-04-14
PL359705A1 (en) 2004-09-06
CZ298718B6 (cs) 2008-01-09
ME00177B (me) 2011-02-10
SK12762002A3 (sk) 2003-04-01
HUP0300135A2 (hu) 2003-06-28
MXPA02008292A (es) 2002-12-09
MEP28808A (bs) 2010-10-10
RU2261701C2 (ru) 2005-10-10
CN1416353A (zh) 2003-05-07
US20030086881A1 (en) 2003-05-08
CA2402267A1 (en) 2001-09-13
NZ521226A (en) 2004-08-27
HRP20020731A2 (en) 2004-12-31
NO330245B1 (no) 2011-03-14
ATE259660T1 (de) 2004-03-15
CN1216642C (zh) 2005-08-31
DE50101510D1 (de) 2004-03-25
ZA200207213B (en) 2003-02-26
IL151519A (en) 2011-07-31
KR20030016237A (ko) 2003-02-26
AU4648401A (en) 2001-09-17
EP1267932A1 (de) 2003-01-02
US20010046478A1 (en) 2001-11-29
NO20024271L (no) 2002-10-18
NO20024271D0 (no) 2002-09-06
SK287076B6 (sk) 2009-11-05

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