BR0109176A - Método para preparação de citalopram e composto da fórmula - Google Patents

Método para preparação de citalopram e composto da fórmula

Info

Publication number
BR0109176A
BR0109176A BR0109176-0A BR0109176A BR0109176A BR 0109176 A BR0109176 A BR 0109176A BR 0109176 A BR0109176 A BR 0109176A BR 0109176 A BR0109176 A BR 0109176A
Authority
BR
Brazil
Prior art keywords
compound
formula
citalopram
preparing citalopram
preparing
Prior art date
Application number
BR0109176-0A
Other languages
English (en)
Inventor
Hans Petersen
Original Assignee
Lundbeck & Co As H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H
Publication of BR0109176A publication Critical patent/BR0109176A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Furan Compounds (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

"MéTODO PARA PREPARAçãO DE CITALOPRAM E COMPOSTO DA FóRMULA". A presente invenção refere-se a um método para preparação de citalopram por alquilação de um derivado de 1-(4-fluorofenil)-1,3-diidroisobenzofurano.
BR0109176-0A 2000-03-13 2001-03-13 Método para preparação de citalopram e composto da fórmula BR0109176A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA200000401 2000-03-13
DKPA200000415 2000-03-14
PCT/DK2001/000168 WO2001068631A1 (en) 2000-03-13 2001-03-13 Method for the preparation of citalopram

Publications (1)

Publication Number Publication Date
BR0109176A true BR0109176A (pt) 2003-04-22

Family

ID=26068790

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0109176-0A BR0109176A (pt) 2000-03-13 2001-03-13 Método para preparação de citalopram e composto da fórmula

Country Status (22)

Country Link
US (2) US6762308B2 (pt)
EP (1) EP1265883A1 (pt)
JP (1) JP2003527387A (pt)
KR (1) KR20020080481A (pt)
CN (1) CN1429219A (pt)
AU (1) AU2001242298A1 (pt)
BG (1) BG107047A (pt)
BR (1) BR0109176A (pt)
CA (1) CA2402388A1 (pt)
CZ (1) CZ20023384A3 (pt)
EA (1) EA200200969A1 (pt)
HR (1) HRP20020744A2 (pt)
HU (1) HUP0300274A2 (pt)
IL (1) IL151490A0 (pt)
IS (1) IS6529A (pt)
MX (1) MXPA02008869A (pt)
NO (1) NO20024213L (pt)
NZ (1) NZ521201A (pt)
PL (1) PL360110A1 (pt)
SK (1) SK14602002A3 (pt)
TR (1) TR200202166T2 (pt)
WO (1) WO2001068631A1 (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL145615A0 (en) * 1999-04-14 2002-06-30 Lundbeck & Co As H Method for the preparation of citalopram
IES20010157A2 (en) 2000-03-03 2002-03-06 Lundbeck & Co As H Method for the preparation of citalopram
BR0109364A (pt) 2000-03-13 2002-12-24 Lundbeck & Co As H Métodos para fabricação de citalopram através de alquilação escalonada de 5-substituìda 1- (4-fluorofenil) - 1,3- diidroisobenzofuranos e citalopram
SK14602002A3 (sk) 2000-03-13 2003-02-04 H. Lundbeck A/S Spôsob výroby citalopramu a medziprodukty
NL1017500C1 (nl) 2000-03-13 2001-04-26 Lundbeck & Co As H Werkwijze voor de bereiding van Citalopram.
IL151488A0 (en) 2000-03-14 2003-04-10 Lundbeck & Co As H Method for the preparation of citalopram
AR032455A1 (es) 2000-05-12 2003-11-12 Lundbeck & Co As H Metodo para la preparacion de citalopram, un intermediario empleado en el metodo, un metodo para la preparacion del intermediario empleado en el metodo y composicion farmaceutica antidepresiva
AR040970A1 (es) 2002-08-12 2005-04-27 Lundbeck & Co As H Metodo para la separacion de intermediarios que pueden ser utilizados para la preparacion de escitalopram
AU2003223105A1 (en) * 2003-03-24 2004-10-18 Hetero Drugs Limited Novel crystalline forms of (s)-citalopram oxalate
TWI339651B (en) 2004-02-12 2011-04-01 Lundbeck & Co As H Method for the separation of intermediates which may be used for the preparation of escitalopram
US7613106B2 (en) * 2005-01-04 2009-11-03 Avaya Inc. Dial plan transparency for fragmented networks
GB0601286D0 (en) 2006-01-23 2006-03-01 Sandoz Ag Asymmetric synthesis

Family Cites Families (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1143703A (pt) 1965-03-18
GB1526331A (en) 1976-01-14 1978-09-27 Kefalas As Phthalanes
GB8419963D0 (en) 1984-08-06 1984-09-12 Lundbeck & Co As H Intermediate compound and method
GB8814057D0 (en) 1988-06-14 1988-07-20 Lundbeck & Co As H New enantiomers & their isolation
US5296507A (en) 1990-09-06 1994-03-22 H.Lundbeck A/S Treatment of cerbrovascular disorders
DE19626659A1 (de) 1996-07-03 1998-01-08 Basf Ag Verfahren zur Herstellung von Phthaliden
DE19627697A1 (de) 1996-07-10 1998-01-15 Basf Ag Verfahren zur Herstellung von Phthaliden
JP3526581B2 (ja) 1997-07-08 2004-05-17 ハー・ルンドベック・アクティーゼルスカブ シタロプラムの製造方法
UA62985C2 (en) 1997-11-10 2004-01-15 Lunnbeck As H A method for the preparation of citalopram
CN1286687A (zh) 1997-11-11 2001-03-07 H·隆德贝克有限公司 制备西酞普兰的方法
WO2000023431A1 (en) 1998-10-20 2000-04-27 H. Lundbeck A/S Method for the preparation of citalopram
HK1043130B (zh) 1998-12-23 2005-03-04 H‧隆德贝克有限公司 制备5-氰基2-苯并[c]呋喃酮的方法
AR022329A1 (es) 1999-01-29 2002-09-04 Lundbeck & Co As H Metodo para la preparacion de 5-cianoftalida
IL145615A0 (en) 1999-04-14 2002-06-30 Lundbeck & Co As H Method for the preparation of citalopram
ITMI991579A1 (it) 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
ITMI991581A1 (it) 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
GB2360281B (en) 1999-10-25 2002-01-16 Lundbeck & Co As H Method for the preparation of citalopram
US6310222B1 (en) 1999-11-01 2001-10-30 Sumika Fine Chemicals Co., Ltd. Production method of 5-phthalancarbonitrile compound, intermediate therefor and production method of the intermediate
AR026063A1 (es) 1999-11-01 2002-12-26 Lundbeck & Co As H Metodo para la preparacion de 5-carboxiftalida.
NZ519739A (en) 1999-12-28 2004-03-26 H Method for the preparation of citalopram
PT1246813E (pt) 1999-12-30 2004-02-27 Lundbeck & Co As H Metodo para a preparacao de citalopram
WO2001051477A1 (en) 2000-01-14 2001-07-19 H. Lundbeck A/S Method for the preparation of 5-cyanophthalide
US6433196B1 (en) 2000-02-17 2002-08-13 Sumika Fine Chemicals Co., Ltd. Production method of citalopram, intermediate therefor and production method of the intermediate
NL1017415C1 (nl) 2000-02-24 2001-05-18 Lundbeck & Co As H Werkwijze voor de bereiding van Citalopram.
IES20010143A2 (en) 2000-02-24 2001-07-25 Lundbeck & Co As H Method for the preparation of citalopram
IES20010157A2 (en) 2000-03-03 2002-03-06 Lundbeck & Co As H Method for the preparation of citalopram
GB0005477D0 (en) 2000-03-07 2000-04-26 Resolution Chemicals Limited Process for the preparation of citalopram
NL1017500C1 (nl) 2000-03-13 2001-04-26 Lundbeck & Co As H Werkwijze voor de bereiding van Citalopram.
SK14602002A3 (sk) 2000-03-13 2003-02-04 H. Lundbeck A/S Spôsob výroby citalopramu a medziprodukty
IL151488A0 (en) 2000-03-14 2003-04-10 Lundbeck & Co As H Method for the preparation of citalopram
TR200202168T2 (tr) 2000-03-16 2002-12-23 H. Lundbeck A/S 5-Siyano-1-(4-Florofenil)-1,3-Dihidroizobenzofuranların preparasyon metodu
SK3362002A3 (en) 2000-07-06 2002-08-06 Lundbeck & Co As H Method for the preparation of citalopram
IL144816A (en) 2000-08-18 2005-09-25 Lundbeck & Co As H Method for the preparation of citalopram
TR200201166T1 (tr) 2000-12-22 2002-10-21 H.Lundbecks A/S Saf sitalopram hazırlanması için yöntem
JP2003519121A (ja) 2000-12-28 2003-06-17 ハー・ルンドベック・アクチエゼルスカベット 純粋なシタロプラムの製造方法

Also Published As

Publication number Publication date
HRP20020744A2 (en) 2004-12-31
US20040215025A1 (en) 2004-10-28
NO20024213D0 (no) 2002-09-04
HUP0300274A2 (hu) 2003-06-28
WO2001068631A1 (en) 2001-09-20
US20030092919A1 (en) 2003-05-15
EA200200969A1 (ru) 2003-02-27
CA2402388A1 (en) 2001-09-20
US6762308B2 (en) 2004-07-13
JP2003527387A (ja) 2003-09-16
EP1265883A1 (en) 2002-12-18
US6992198B2 (en) 2006-01-31
TR200202166T2 (tr) 2002-12-23
IL151490A0 (en) 2003-04-10
MXPA02008869A (es) 2003-02-10
NO20024213L (no) 2002-11-13
KR20020080481A (ko) 2002-10-23
CN1429219A (zh) 2003-07-09
AU2001242298A1 (en) 2001-09-24
IS6529A (is) 2002-08-27
PL360110A1 (en) 2004-09-06
SK14602002A3 (sk) 2003-02-04
CZ20023384A3 (cs) 2003-01-15
NZ521201A (en) 2004-02-27
BG107047A (en) 2003-04-30

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 5A, 6A E 7A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO PUBLICADO NA RPI 1963 DE 19.08.2008.